Cell Transformation, Viral
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Subject Areas on Research
- A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein.
- A genetically tractable model of human glioma formation.
- A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis.
- A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice.
- A research for the relationship between human papillomavirus and human uterine cervical carcinoma. II. Molecular genetic and ultrastructural study on the transforming activity of recombinant retrovirus containing human papillomavirus type 16 subgenomic sequences.
- A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus.
- A viral microRNA functions as an orthologue of cellular miR-155.
- Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells.
- Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.
- Alterations within pp59v-rel-containing protein complexes following the stimulation of REV-T-transformed lymphoid cells with zinc.
- An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells.
- Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation.
- Antibodies to human T-cell lymphotropic virus-I membrane antigens and inverted T4/T8 ratios in hemophiliacs.
- Antibody-dependent enhancement of simian immunodeficiency virus (SIV) infection in vitro by plasma from SIV-infected rhesus macaques.
- Calmodulin is involved in regulation of cell proliferation.
- Carcinogenesis in urogenital sites.
- Characterization of antigens in SSV nonproducer cells.
- Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture.
- Clonal isolate of the simian sarcoma virus codes for a Gag-related 65,000-dalton protein.
- Complement receptor expression by neoplastic and normal human cells.
- DNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor.
- Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand...
- Detection of a transformation-specific glycopeptide in SSV-infected cells.
- Development of suppressor T lymphocytes for Epstein-Barr virus-induced B-lymphocyte outgrowth during acute infectious mononucleosis: assessment by two quantitative systems.
- Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.
- Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines.
- Differential properties among clones of simian virus 40-transformed human epithelial cells.
- Differential retention of rhodamine 123 by avian sarcoma virus-induced glioma and normal brain tissue of the rat in vivo.
- Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.
- Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line.
- Dynamic Epstein-Barr virus gene expression on the path to B-cell transformation.
- Effect of intron size on splicing efficiency in retroviral transcripts.
- Effects of the src gene product on microfilament and microtubule organization in avian and mammalian cells infected with the same temperature-sensitive mutant of Rous sarcoma virus.
- Endogenous avian retroviruses contain deficient promoter and leader sequences.
- Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
- Epstein Barr virus binding induces internalization of the C3d receptor: a novel immunotoxin delivery system.
- Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency.
- Expression of major histocompatibility complex class I antigens in normal and transformed rat thyroid epithelial cell lines.
- F-actin aggregates in transformed cells.
- Function of cytoplasmic fibers in syncytia.
- Fusion of the termini of the murine cytomegalovirus genome after infection.
- HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression.
- Herpesvirus saimiri transformation of HIV type 1 suppressive CD8+ lymphocytes from an HIV type 1-infected asymptomatic individual.
- Identification of a 20,000-dalton protein in SSV-transformed nonproducer cells.
- In-vitro infection of chronic lymphocytic leukemia cells by Epstein-Barr virus (EBV).
- Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a.
- Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.
- Inhibition of Neu-induced mammary carcinogenesis in transgenic mice expressing ERΔ3, a dominant negative estrogen receptor α variant.
- Ion fluxes and differentiation in transformed cell lines.
- Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.
- Localization and characterization of the src-gene product of Rous sarcoma virus.
- MDM2-dependent inhibition of p53 is required for Epstein-Barr virus B-cell growth transformation and infected-cell survival.
- Metabolic stress is a barrier to Epstein-Barr virus-mediated B-cell immortalization.
- Mutants of Fujinami sarcoma virus which are temperature sensitive for cellular transformation and protein kinase activity.
- Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism.
- Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.
- Porphyromonas gingivalis-mediated Epithelial Cell Entry of HIV-1.
- Post-transplantation B cell function in different molecular types of SCID.
- Production of a human monoclonal antibody to HLA by human-human hybridoma technology. A preliminary report.
- Qa-1, a nonclassical MHC molecule with immunomodulatory functions, is ubiquitously expressed in the immune-privileged anterior chamber of the eye.
- RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells.
- Rapid analysis of small nucleic acid samples by gel electrophoresis.
- Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells.
- Regulation of E2A gene expression in B-lymphocyte development.
- Regulation of intracellular levels of calmodulin and tubulin in normal and transformed cells.
- Replication of the vesicular stomatitis virus genome in permissive and nonpermissive host cells.
- Retroviral protein P15E and tumorigenesis. Expression is neither required nor sufficient for tumor development.
- Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus.
- Reversion from deficiency of galactose-1-phosphate uridylytransferase (GALT) in an SV40-transformed human fibroblast line.
- Role of the ABL oncogene tyrosine kinase activity in human leukaemia.
- Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40.
- Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.
- Structure and morphogenesis of type-C retroviruses.
- Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
- The DNA damage response in viral-induced cellular transformation.
- The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes.
- The relationship of modulation of major histocompatibility complex class I antigens to retrovirus transformation in rat cell lines.
- The role of the subependymal plate in glial tumorigenesis.
- The viral and cellular microRNA targetome in lymphoblastoid cell lines.
- To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis.
- Transactivation of BKV and SV40 early promoters by BKV and SV40 T-antigens.
- Transcription in mouse embryo cells permissively infected by murine cytomegalovirus.
- Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis.
- Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers.
- Transformation of hairy cell leukemia to EBV genome-containing aggressive B cell lymphoma.
- Vaccinia virus directs the synthesis of early mRNAs containing 5' poly(A) sequences.
- Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus.
- p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells.
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Keywords of People
- Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology