Central Nervous System Diseases

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  Subject Areas on Research

  • A differential diagnosis of central nervous system demyelination: beyond multiple sclerosis. 
  • Adverse events after discontinuing medications in elderly outpatients. 
  • Behavioral evaluation of perinatal PCB exposure in rhesus monkeys: fixed-interval performance and reinforcement-omission. 
  • Biomaterials for the central nervous system. 
  • Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. 
  • Cardiopulmonary bypass and the central nervous system: potential for cerebral protection. 
  • Cell therapy for diverse central nervous system disorders: inherited metabolic diseases and autism. 
  • Central nervous system leukaemia. 
  • Central nervous system metastases in malignant melanoma. 
  • Central nervous system toxicity following the administration of levobupivacaine for lumbar plexus block: A report of two cases. 
  • Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria. 
  • Clinical and imaging manifestations of pediatric sarcoidosis. 
  • Clinical applications involving CNS gene transfer. 
  • Clinical proton MR spectroscopy in central nervous system disorders. 
  • Contrast-enhanced MR imaging of neurocutaneous melanosis. 
  • Cytogenetics and molecular genetics: their status and role in understanding the behavior of central nervous system neoplasms. 
  • Degeneration of the central nervous system associated with celiac disease. 
  • Delayed onset of neurosarcoidosis after concurrent ipilimumab/nivolumab therapy. 
  • Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators. 
  • Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography. 
  • Differentiation of central nervous system lesions in AIDS patients using positron emission tomography (PET). 
  • Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. 
  • Dizziness in a community elderly population. 
  • ECT and seizure threshold: effects of stimulus wave form and electrode placement. 
  • Epidemiology and Characteristics of Neurosurgical Conditions at Mbarara Regional Referral Hospital. 
  • Evaluation of optic nerve development in preterm and term infants using handheld spectral-domain optical coherence tomography. 
  • Extra-intestinal manifestations of salmonella infections. 
  • Familial aggregation of multiple myeloma and central nervous system diseases. 
  • Fetal mechanisms in neurodevelopmental disorders. 
  • Finite element analysis of bioelectric phenomena. 
  • Hematopoietic stem-cell transplantation in globoid-cell leukodystrophy. 
  • Iatrogenic Baclofen Neurotoxicity in ESRD: Recognition and Management. 
  • Identifying predictors of central nervous system disease in solid organ transplant recipients with cryptococcosis. 
  • Imaging of Herpesvirus Infections of the CNS. 
  • Immediate and delayed neurotoxicity after mechlorethamine preparation for bone marrow transplantation. 
  • Immune reconstitution inflammatory syndrome involving the central nervous system in a patient with HIV infection: a case report and review of literature. 
  • Interventional neuroradiology--anesthetic considerations. 
  • Islands of Inflammation: Neurosarcoidosis. 
  • Large vessel vasculitis of the central nervous system in systemic lupus erythematosus: report and review of the literature. 
  • Letter: Staphylococcal septicaemia and C.N.S. involvement. 
  • Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis. 
  • Long term effects and quality of life in children and adults after marrow transplantation. 
  • Magnetic resonance imaging in patients with central nervous system pathology: a comparison of OptiMARK (Gd-DTPA-BMEA) and Magnevist (Gd-DTPA). 
  • Medical management of adrenal cortical disease. 
  • Meningeal mycosis fungoides: clinical and cellular characteristics. 
  • Metabolomics: a global biochemical approach to the study of central nervous system diseases. 
  • Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders. 
  • Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. 
  • Miscellaneous vasculitic syndromes including Behçet's disease and central nervous system vasculitis. 
  • Mycophenolate mofetil in the treatment of pediatric autoimmune central nervous system disease. 
  • NIAID Mycoses Study Group Multicenter Trial of Oral Itraconazole Therapy for Invasive Aspergillosis. 
  • Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 levels in human amniotic fluid. 
  • Neuroimaging of AIDS. I. Fungal infections of the central nervous system. 
  • Neurologic complications of Rocky Mountain spotted fever. 
  • Neurologic, neurocognitive, and brain growth outcomes in human immunodeficiency virus-infected children receiving different nucleoside antiretroviral regimens. Pediatric AIDS Clinical Trials Group 152 Study Team. 
  • Pathophysiology of the blood-brain barrier: animal models and methods. 
  • Perfusion MRI: the five most frequently asked clinical questions. 
  • Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study. 
  • Phase II trial of intravenous CI-980 (NSC 370147) in patients with metastatic colorectal carcinoma. Model for prospective evaluation of neurotoxicity. 
  • Practice guidelines for the management of cryptococcal disease. Infectious Diseases Society of America. 
  • Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity. 
  • Primary central nervous system posttransplant lymphoproliferative disorders. 
  • Proceedings of the 2013 CINP summit: innovative partnerships to accelerate CNS drug discovery for improved patient care. 
  • Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease. 
  • Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges. 
  • Re: Toxicity of intrathecal melphalan. 
  • Regulation of synaptic connectivity by glia. 
  • Safety and efficacy of brimonidine in children with glaucoma. 
  • Shared features in the pathobiology of babesiosis and malaria. 
  • Statement of consensus on assessment of neurobehavioral outcomes after cardiac surgery. 
  • Systemic lupus erythematosus. 
  • Ten-year experience with primary ocular 'reticulum cell sarcoma' (large cell non-Hodgkin's lymphoma). 
  • The use of recombinant activated factor VII in three patients with central nervous system hemorrhages associated with factor VII deficiency. 
  • Toxoplasma gondii serology in HIV-infected patients: the development of central nervous system toxoplasmosis in AIDS. 
  • Translational research in acute central nervous system injury: lessons learned and the future. 
  • Treatment of patients with recurrent gliomas with cyclophosphamide and vincristine. 
  • Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: ethical challenges. 
  • Updating Neuroimmune Targets in Central Nervous System Dysfunction. 
  • Vascular Involvement in Neurosarcoidosis: Early Experiences From Intracranial Vessel Wall Imaging. 
  • Viral-Mediated Gene Replacement Therapy in the Developing Central Nervous System: Current Status and Future Directions. 
  • Worldwide Organization of Neurocritical Care: Results from the PRINCE Study Part 1. 
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  Keywords of People

  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering