Cephalosporins

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  Subject Areas on Research

  • A Cephalosporin Prochelator Inhibits New Delhi Metallo-β-lactamase 1 without Removing Zinc. 
  • A five-year multicenter study of the susceptibility of the Bacteroides fragilis group isolates to cephalosporins, cephamins, penicillins, clindamycin, and metronidazole in the United States. 
  • A trial of prophylactic cefamandole in extended gynecologic surgery. 
  • Antibiotic prophylaxis for hemodialysis access placement. 
  • Antibiotic prophylaxis in percutaneous endoscopic gastrostomy. 
  • CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. 
  • CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. 
  • Cefazolin in the treatment of bacterial pneumonia. 
  • Cefepime and Ceftazidime Safety in Hospitalized Infants. 
  • Cefoperazone as a prophylactic agent in abdominal hysterectomy. 
  • Ceftaroline applications for therapy in the United States. 
  • Ceftaroline for complicated skin and skin-structure infections. 
  • Ceftaroline fosamil for treatment of community-acquired pneumonia: findings from FOCUS 1 and 2 and potential role in therapy. 
  • Ceftaroline: a cephalosporin with expanded Gram-positive activity. 
  • Ceftaroline: clinical and microbiology experience with focus on methicillin-resistant Staphylococcus aureus after regulatory approval in the USA. 
  • Ceftobiprole versus daptomycin in Staphylococcus aureus bacteremia: a novel protocol for a double-blind, Phase III trial. 
  • Ceftriaxone once daily for four weeks compared with ceftriaxone plus gentamicin once daily for two weeks for treatment of endocarditis due to penicillin-susceptible streptococci. Endocarditis Treatment Consortium Group. 
  • Cephradine concentrations in serum, pleural fluid, pleura, and lung of normal rabbits. 
  • Clostridium difficile infection in obstetric and gynecologic patients. 
  • Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. 
  • Comparison of in vitro activity of moxalactam (LY127935) with cefazolin, amikacin, tobramycin, carbenicillin, piperacillin, and ticarcillin against 420 blood culture isolates. 
  • Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria. 
  • Determination of an inoculum effect with various cephalosporins among clinical isolates of methicillin-susceptible Staphylococcus aureus. 
  • Dosing antibiotics in neonates: review of the pharmacokinetic data. 
  • Efficacy of anti-pseudomonal antibiotics: need to reconsider the empirical use of cefepime. 
  • Endocarditis caused by Bacillus subtilis. 
  • Evaluation of cefazolin, a new cephalosporin antibiotic. 
  • Evaluation of eight cephalosporins in hamster colitis model. 
  • High-dose cefamandole therapy in obstetric and gynecologic infections. 
  • History of antibiotics. From salvarsan to cephalosporins. 
  • Image of the month. Pyogenic liver abscess. 
  • Impact of education on cephalosporin prescribing patterns. 
  • In vivo activity and pharmacokinetics of ziracin (SCH27899), a new long-acting everninomicin antibiotic, in a murine model of penicillin-susceptible or penicillin-resistant pneumococcal pneumonia. 
  • Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. 
  • Interpretive criteria and quality control limits for ceftibuten disk susceptibility tests. Collaborative Antimicrobial Susceptibility Testing Group. 
  • Moxalactam therapy for obstetric and gynecologic infections. 
  • Neonatal fungal infections: when to treat? 
  • New treatments for methicillin-resistant Staphylococcus aureus. 
  • Outpatient versus inpatient IV antibiotic management for pediatric oncology patients with low risk febrile neutropenia: a randomised trial. 
  • Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies. 
  • Penetration of cephradine into normal, inflammatory, and infected pleural fluids in rabbits. 
  • Pharmacokinetics and Safety of Ceftobiprole in Pediatric Patients. 
  • Pharmacokinetics of cefoperazone, moxalactam, cefotaxime, trimethoprim and sulphamethoxazole in experimental meningitis. 
  • Potential value of cefoperazone in bacterial meningitis: experimental studies. 
  • Prospective randomized double-blind comparison of moxalactam and tobramycin in treatment of urinary tract infections. 
  • Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV. 
  • Rickettsialpox in North Carolina: a case report. 
  • Risk factors for postoperative mediastinitis due to methicillin-resistant Staphylococcus aureus. 
  • Surgical infection prophylaxis prior to left ventricular assist device implantation: A survey of clinical practice. 
  • Susceptibility of Clostridium perfringens isolated from human infections to twenty antibiotics. 
  • TD-1792 versus vancomycin for treatment of complicated skin and skin structure infections. 
  • Tests for 2 x K contingency tables with clustered ordered categorical data. 
  • The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants. 
  • The impact of patient-reported penicillin or cephalosporin allergy on surgical site infections. 
  • The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. 
  • When to suspect fungal infection in neonates: A clinical comparison of Candida albicans and Candida parapsilosis fungemia with coagulase-negative staphylococcal bacteremia.