Cerebellum

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  Subject Areas on Research

  • 2-[18F]F-A-85380: a PET radioligand for alpha4beta2 nicotinic acetylcholine receptors. 
  • A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice. 
  • A framework for using signal, noise, and variation to determine whether the brain controls movement synergies or single muscles. 
  • A neural network approach to hippocampal function in classical conditioning. 
  • A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum. 
  • A recurrent cerebellar lesion in a young boy. 
  • A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. 
  • AHI1 mutations cause both retinal dystrophy and renal cystic disease in Joubert syndrome. 
  • ATM binds to beta-adaptin in cytoplasmic vesicles. 
  • Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. 
  • Abnormal cerebellar signaling induces dystonia in mice. 
  • Abnormalities of the corpus callosum in nonpsychotic children with chromosome 22q11 deletion syndrome. 
  • Acquisition of neural learning in cerebellum and cerebral cortex for smooth pursuit eye movements. 
  • Acute exposure to sarin increases blood brain barrier permeability and induces neuropathological changes in the rat brain: dose-response relationships. 
  • Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS alpha 7 nicotinic acetylcholine receptors. 
  • Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease. 
  • Alterations of excitatory amino acid receptors in the brain of manganese-treated mice. 
  • Altered cerebellar-cerebral functional connectivity in geriatric depression. 
  • Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally. 
  • Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients. 
  • Altered gabaa receptor subunit and splice variant expression in rats treated with chronic intermittent ethanol. 
  • Alternative splicing of the GABA(A) receptor alpha 4 subunit creates a severely truncated mRNA. 
  • Amelioration of the behavioral phenotype in genetically ataxic mice through bilateral intracerebellar grafting of fetal Purkinje cells. 
  • An animal model of MYC-driven medulloblastoma. 
  • An in vitro bioassay for neurite growth using cryostat sections of nervous tissue as a substratum. 
  • An intermediate filament-associated protein, p50, recognized by monoclonal antibodies. 
  • Analysis of gene expression in the normal and malignant cerebellum. 
  • Analysis of the expression, distribution and function of cyclin dependent kinase 5 (cdk5) in developing cerebellar macroneurons. 
  • Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments. 
  • AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing. 
  • Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse. 
  • Apolipoprotein-E allele-specific regulation of nitric oxide production. 
  • Argyrophilic plaque-like deposits in children. 
  • Association between blood lead and walking speed in the National Health and Nutrition Examination Survey (NHANES 1999-2002). 
  • Attention, configuration, and hippocampal function. 
  • Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. 
  • BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV. 
  • Behavioral characterization of P311 knockout mice. 
  • Beta-2 adrenergic control of ornithine decarboxylase activity in brain regions of the developing rat. 
  • Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF). 
  • Blood flow and metabolism in heterotopic cerebellar grafts during hypoglycemia. 
  • Brain structural abnormalities in young children with autism spectrum disorder. 
  • Brain-derived neurotrophic factor attenuates mouse cerebellar granule cell GABA(A) receptor-mediated responses via postsynaptic mechanisms. 
  • C-fos mRNA induction in the central and peripheral nervous systems of diisopropyl phosphorofluoridate (DFP)-treated hens. 
  • CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. 
  • Carcinomatous cerebellar degeneration, encephalomyelitis, and sensory neuropathy (radiculitis). Report of a case incorporating both purely degenerative and intense inflammatory changes, with special prominence of the latter in the putamen. 
  • Caught in the matrix: how vitronectin controls neuronal differentiation. 
  • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. 
  • Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions. 
  • Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. 
  • Cerebellar LTD: a molecular mechanism of behavioral learning? 
  • Cerebellar activity and disturbed time sense after THC. 
  • Cerebellar and cerebral electroencephalogram during the high pressure nervous syndrome (HPNS) in rats. 
  • Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice. 
  • Cerebellar flocculus hypothesis. 
  • Cerebellar hemorrhage as evaluated by computerized tomography. 
  • Cerebellar learning using perturbations. 
  • Cerebellar networks in individuals at ultra high-risk of psychosis: impact on postural sway and symptom severity. 
  • Cerebellar vermal volumes and behavioral correlates in children with autism spectrum disorder. 
  • Cerebellar vermian defects: antenatal sonographic appearance and clinical significance. 
  • Cerebellar vermis hypoplasia in a case of cri-du-chat syndrome. 
  • Cerebellar volumes in pediatric maltreatment-related posttraumatic stress disorder. 
  • Cerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism. 
  • Changes in the responses of Purkinje cells in the floccular complex of monkeys after motor learning in smooth pursuit eye movements. 
  • Characterization and distribution of protein kinase C isoforms in human skin fibroblasts. 
  • Characterization of cardiac A1 adenosine receptors by ligand binding and photoaffinity labeling. 
  • Characterization of the radioiodinated analogue of SCH 23390: in vitro and in vivo D-1 dopamine receptor binding studies. 
  • Childhood cerebellar tumours mirror conserved fetal transcriptional programs. 
  • Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice. 
  • Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum. 
  • Combining patch-clamp and optical methods in brain slices. 
  • Compression of the medulla oblongata and acute respiratory failure caused by rupture of a thrombosed large aneurysm of the anterior inferior cerebellar artery. 
  • Consensus paper: Decoding the Contributions of the Cerebellum as a Time Machine. From Neurons to Clinical Applications. 
  • Continuing education course #3: current practices and future trends in neuropathology assessment for developmental neurotoxicity testing. 
  • Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. 
  • Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions. 
  • Cyclophosphamide treatment used to manipulate the immune response for the production of monoclonal antibodies. 
  • De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. 
  • Decreased IGF-I gene expression during the apoptosis of Purkinje cells in pcd mice. 
  • Defects of ocular motility after stereotactic midbrain lesions in man. 
  • Deletion including the oligophrenin-1 gene associated with enlarged cerebral ventricles, cerebellar hypoplasia, seizures and ataxia. 
  • Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions. 
  • Developmental changes of RNA editing of glutamate receptor subunits GluR5 and GluR6: in vivo versus in vitro. 
  • Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation. 
  • Differential alteration of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP). 
  • Diffusion Tensor Imaging Detects Occult Cerebellar Injury in Severe Neonatal Hypoxic-Ischemic Encephalopathy. 
  • Directional organization of eye movement and visual signals in the floccular lobe of the monkey cerebellum. 
  • Diversity of neural responses in the brainstem during smooth pursuit eye movements constrains the circuit mechanisms of neural integration. 
  • Doing without learning: stimulation of the frontal eye fields and floccular complex does not instruct motor learning in smooth pursuit eye movements. 
  • Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity. 
  • Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound. 
  • Early differential induction of C-jun in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP). 
  • Effect of cerebellar ablation on the high pressure nervous syndrome in rats. 
  • Effect of maternal ethanol ingestion on neonatal rat brain and heart ornithine decarboxylase. 
  • Effect of photoperiod reversal on twenty-four hour patterns for GABA levels in rat brain. 
  • Effects of late prenatal or early postnatal ethanol exposure on ornithine decarboxylase activity in brain and heart of developing rats. 
  • Effects of neonatal hypoxia on brain development in the rat: immediate and long-term biochemical alterations in discrete regions. 
  • Effects of neonatal methylmercury exposure on development of nucleic acids and proteins in rat brain: regional specificity. 
  • Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat. 
  • Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network. 
  • Electrical recording with micro- and macroelectrodes from the cerebellum of man. 
  • Elevated intracellular calcium levels in cerebellar granule neurons of weaver mice. 
  • Embarrassed, but not depressed: eye opening lessons for cerebellar learning. 
  • Encoding and decoding of learned smooth-pursuit eye movements in the floccular complex of the monkey cerebellum. 
  • Endoscopic supracerebellar infratentorial approach for pineal cyst resection: technical case report. 
  • Enhanced mRNA expression of neurofilament subunits in the brain and spinal cord of diisopropyl phosphorofluoridate-treated hens. 
  • Error associated with the choice of an aortic cannula in measuring regional cerebral blood flow with microspheres during pulsatile CPB in a neonatal piglet model. 
  • Ethanol exposure alters the phosphorylation of cyclic AMP responsive element binding protein and cyclic AMP responsive element binding activity in rat cerebellum. 
  • Evidence for altered cerebellar vermis neuronal integrity in schizophrenia. 
  • Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome. 
  • Experience-dependent changes in cerebellar contributions to motor sequence learning. 
  • Expression of cyp26b1 during zebrafish early development. 
  • Eye movements and brainstem neuronal responses evoked by cerebellar and vestibular stimulation in chicks. 
  • FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. 
  • FGF14 regulates presynaptic Ca2+ channels and synaptic transmission. 
  • Factors influencing the cell type of brain tumors induced in dogs by Schmidt-Ruppin Rous sarcoma virus. 
  • Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. 
  • Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors. 
  • Fetal terbutaline exposure causes selective postnatal increases in cerebellar alpha-adrenergic receptor binding. 
  • Floccular efferents in the rhesus macaque as revealed by autoradiography and horseradish peroxidase. 
  • Fluorescence imaging of changes in intracellular chloride in living brain slices. 
  • Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. 
  • Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome. 
  • Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length. 
  • Genetic modifiers of the Kv beta2-null phenotype in mice. 
  • Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats. 
  • Graft-induced restoration of function in hereditary cerebellar ataxia. 
  • Grafted cerebellar cells in a mouse model of hereditary ataxia express IGF-I system genes and partially restore behavioral function. 
  • Heroin neuroteratogenicity: targeting adenylyl cyclase as an underlying biochemical mechanism. 
  • High-frequency organization and synchrony of activity in the purkinje cell layer of the cerebellum. 
  • Hippocampectomy disrupts the topography of the rat eyeblink response during acquisition and extinction of classical conditioning. 
  • Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. 
  • Hypotheses about the neural trigger for plasticity in the circuit for the vestibulo-ocular reflex. 
  • Identification and characterization of adrenergic receptors and catecholamine-stimulated adenylate cyclase in hog pial membranes. 
  • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. 
  • Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. 
  • Impact of adolescent nicotine exposure on adenylyl cyclase-mediated cell signaling: enzyme induction, neurotransmitter-specific effects, regional selectivities, and the role of withdrawal. 
  • Impairment in motor learning of somatostatin null mutant mice. 
  • Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. 
  • In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions. 
  • In vivo stereological assessment of human cerebellar volume: effects of gender and age. 
  • Increased alkaline phosphatase specific activity in reeler cerebella. 
  • Increased brain apparent diffusion coefficient in children with neurofibromatosis type 1. 
  • Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. 
  • Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. 
  • Influence of regional iron on the motor impairments of Parkinson's disease: A quantitative susceptibility mapping study. 
  • Infratentorial and supratentorial strokes after a cranioplasty. 
  • Interaction of plasticity and circuit organization during the acquisition of cerebellum-dependent motor learning. 
  • Interactive roles of the cerebellum and striatum in sub-second and supra-second timing: Support for an initiation, continuation, adjustment, and termination (ICAT) model of temporal processing. 
  • Internal models of eye movement in the floccular complex of the monkey cerebellum. 
  • Intraoperative rupture of brainstem cavernous malformation. Case report. 
  • Isolation of neural stem cells from the postnatal cerebellum. 
  • Joubert Syndrome in French Canadians and Identification of Mutations in CEP104. 
  • Joubert syndrome: a haplotype segregation strategy and exclusion of the zinc finger protein of cerebellum 1 (ZIC1) gene. 
  • Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression. 
  • L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow. 
  • Lateralization of prefrontal activity during episodic memory retrieval: evidence for the production-monitoring hypothesis. 
  • Learning. A mechanism of learning found? 
  • Leukoencephalopathy in elderly depressed patients referred for ECT. 
  • Limitations of brain stem auditory evoked potentials for intraoperative monitoring during a posterior fossa operation: case report and technical note. 
  • Limited regional cerebellar dysfunction induces focal dystonia in mice. 
  • Links from complex spikes to local plasticity and motor learning in the cerebellum of awake-behaving monkeys. 
  • Local calcium release in dendritic spines required for long-term synaptic depression. 
  • Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. 
  • Local dendritic Ca2+ signaling induces cerebellar long-term depression. 
  • Localization of calmodulin in rat cerebellum by immunoelectron microscopy. 
  • Localization of neuron-specific enolase (NSE) mRNA in human brain. 
  • Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma. 
  • Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration. 
  • MR of the brain in mitochondrial myopathy. 
  • Magnetic resonance imaging (MRI)--morphometric study. 
  • Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. 
  • Maternal exposure of rats to nicotine via infusion during gestation produces neurobehavioral deficits and elevated expression of glial fibrillary acidic protein in the cerebellum and CA1 subfield in the offspring at puberty. 
  • Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty. 
  • Measurement of evoked potentials during thalamic deep brain stimulation. 
  • Measurement of the transverse cerebellar diameter in preterm neonates and its use in assessment of gestational age. 
  • Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum. 
  • Microwave-stimulated recovery of myosin-V immunoreactivity from formalin-fixed, paraffin-embedded human CNS. 
  • Mild cognitive impairment: evaluation with 4-T functional MR imaging. 
  • Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. 
  • Modes of interactions between signaling pathways. 
  • Modulation of Complex-Spike Duration and Probability during Cerebellar Motor Learning in Visually Guided Smooth-Pursuit Eye Movements of Monkeys. 
  • Molecular biology of adrenergic receptors in the rat and frog central nervous system. 
  • Monoclonal antibodies to epitopes on different regions of the 200 000 dalton neurofilament protein. Probes for the geometry of the filament. 
  • Multiple components in direction learning in smooth pursuit eye movements of monkeys. 
  • Multiple subclasses of Purkinje cells in the primate floccular complex provide similar signals to guide learning in the vestibulo-ocular reflex. 
  • Multitasking on the run. 
  • Mutations in CSPP1, encoding a core centrosomal protein, cause a range of ciliopathy phenotypes in humans. 
  • N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. 
  • N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma. 
  • N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors. 
  • NMDA receptor subtypes at autaptic synapses of cerebellar granule neurons. 
  • Nasal toxicity of manganese sulfate and manganese phosphate in young male rats following subchronic (13-week) inhalation exposure. 
  • Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. 
  • Neonatal organophosphorus pesticide exposure alters the developmental trajectory of cell-signaling cascades controlling metabolism: differential effects of diazinon and parathion. 
  • Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum. 
  • Neonatal polyamine depletion by alpha-difluoromethylornithine: effects on adenylyl cyclase cell signaling are separable from effects on brain region growth. 
  • Neural activation for actual and imagined movement following unilateral hand transplantation: a case study. 
  • Neural basis for motor learning in the vestibuloocular reflex of primates. I. Changes in the responses of brain stem neurons. 
  • Neural basis for motor learning in the vestibuloocular reflex of primates. II. Changes in the responses of horizontal gaze velocity Purkinje cells in the cerebellar flocculus and ventral paraflocculus. 
  • Neural basis for motor learning in the vestibuloocular reflex of primates. III. Computational and behavioral analysis of the sites of learning. 
  • Neural circuit repair by low-intensity magnetic stimulation requires cellular magnetoreceptors and specific stimulation patterns. 
  • Neural correlates of cognitive and affective processing in maltreated youth with posttraumatic stress symptoms: does gender matter? 
  • Neural recordings and behavioral observations in the monkey vestibulo-ocular reflex constrain the cellular mechanisms for cerebellum-dependent behavioral learning. 
  • Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cells. 
  • Neurologic outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats: description of a new model. 
  • Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. 
  • Neuronal morphology generates high-frequency firing resonance. 
  • Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. 
  • Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine. 
  • Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine. 
  • Novel CASK mutations in cases with syndromic microcephaly. 
  • Novel localization of a G protein, Gz-alpha, in neurons of brain and retina. 
  • Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. 
  • Ocular reactions in man from deep cerebellar stimulation and lesions. 
  • Optical imaging of intracellular chloride in living brain slices. 
  • PLCgamma signaling underlies BDNF potentiation of Purkinje cell responses to GABA. 
  • Partial ablations of the flocculus and ventral paraflocculus in monkeys cause linked deficits in smooth pursuit eye movements and adaptive modification of the VOR. 
  • Pathologic assessment of cerebellar atrophy following acute lithium intoxication. 
  • Persistent neurobehavioral effects of early postnatal domoic acid exposure in rats. 
  • Pharmacologically distinct presynaptic calcium channels in cerebellar excitatory and inhibitory synapses. 
  • Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects. 
  • Phenotypic characterization of murine models of cerebral cavernous malformations. 
  • Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15. 
  • Phenotypic spectrum and prevalence of INPP5E mutations in Joubert syndrome and related disorders. 
  • Photochemical control of endogenous ion channels and cellular excitability. 
  • Physical exercise increases involvement of motor networks as a compensatory mechanism during a cognitively challenging task. 
  • Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease. 
  • Plasticity in the vestibulo-ocular reflex: a new hypothesis. 
  • Polychlorinated biphenyl (PCBs)-induced oxidative stress plays a critical role on cerebellar dopaminergic receptor expression: ameliorative role of quercetin. 
  • Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation. 
  • Posterior fossa abnormalities in major depression: a controlled magnetic resonance imaging study. 
  • Posterior structural brain volumes differ in maltreated youth with and without chronic posttraumatic stress disorder. 
  • Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion. 
  • Prefrontal cortex, thalamus, and cerebellar volumes in adolescents and young adults with adolescent-onset alcohol use disorders and comorbid mental disorders. 
  • Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos. 
  • Prenatal terbutaline exposure in the rat: selective effects on development of noradrenergic projections to cerebellum. 
  • Presynaptic input regulates development of beta-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol. 
  • Primary Sjogren's syndrome presenting as acute cerebellitis. 
  • Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL. 
  • Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. 
  • Purkinje cell loss in experimental autoimmune encephalomyelitis. 
  • Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments. 
  • Quantification of spread of cerebellar long-term depression with chemical two-photon uncaging of glutamate. 
  • Quiescent and cycling cell compartments in the senescent and Alzheimer-diseased human brain. 
  • RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. 
  • RPGRIP1L mutations are mainly associated with the cerebello-renal phenotype of Joubert syndrome-related disorders. 
  • Rapid behavioral and genomic responses to social opportunity. 
  • Rat brain synaptic vesicles: uptake specificities of [3H]norepinephrine and [3H]serotonin in preparations from whole brain and brain regions. 
  • Regional differences in brain monoamine oxidase subtypes in an animal model of geriatric depression: effects of olfactory bulbectomy in young versus aged rats. 
  • Regional variation in the presence of mast cells in the mammalian brain. 
  • Regionally specific neuronal expression of human APOE gene in transgenic mice. 
  • Release of corticotropin-releasing factor from rat brain regions in vitro. 
  • Responses during eye movements of brain stem neurons that receive monosynaptic inhibition from the flocculus and ventral paraflocculus in monkeys. 
  • Resting-state thalamic dysconnectivity in schizophrenia and relationships with symptoms. 
  • Retention of VOR gain following short-term VOR adaptation. 
  • Retrosigmoid suprafloccular transhorizontal fissure approach for resection of brainstem cavernous malformation. 
  • Role of arcuate frontal cortex of monkeys in smooth pursuit eye movements. II. Relation to vector averaging pursuit. 
  • Role of plasticity at different sites across the time course of cerebellar motor learning. 
  • Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. I. Purkinje cell activity during visually guided horizontal smooth-pursuit eye movements and passive head rotation. 
  • Sarin (nerve agent GB)-induced differential expression of mRNA coding for the acetylcholinesterase gene in the rat central nervous system. 
  • Sarin causes altered time course of mRNA expression of alpha tubulin in the central nervous system of rats. 
  • Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine. 
  • Search for genes involved in Joubert syndrome: evidence that one or more major loci are yet to be identified and exclusion of candidate genes EN1, EN2, FGF8, and BARHL1. 
  • Selective regulation of beta-2 adrenergic receptors by the chronic administration of the lipophilic beta adrenergic receptor agonist clenbuterol: an autoradiographic study. 
  • Senataxin, A Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration. 
  • Sensory acquisition in the cerebellum: an FMRI study of cerebrocerebellar interaction during visual duration discrimination. 
  • Separate and overlapping brain areas encode subjective value during delay and effort discounting. 
  • Serotonin regulates dynamics of cerebellar granule cell activity by modulating tonic inhibition. 
  • Signal, Noise, and Variation in Neural and Sensory-Motor Latency. 
  • Signals used to compute errors in monkey vestibuloocular reflex: possible role of flocculus. 
  • Simple spike responses of gaze velocity Purkinje cells in the floccular lobe of the monkey during the onset and offset of pursuit eye movements. 
  • Specific photoaffinity labelling of inhibitory adenosine receptors. 
  • Stimulus configuration, classical conditioning, and hippocampal function. 
  • Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum. 
  • Structural alterations within cerebellar circuitry are associated with general liability for common mental disorders. 
  • Subchronic dermal application of N,N-diethyl m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the cerebellum. 
  • Subtelomeric deletions of chromosome 6p: molecular and cytogenetic characterization of three new cases with phenotypic overlap with Ritscher-Schinzel (3C) syndrome. 
  • Superior cerebellar grooves in relation to upward transtentorial herniation. 
  • Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography. 
  • Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. 
  • TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. 
  • Terbutaline is a developmental neurotoxicant: effects on neuroproteins and morphology in cerebellum, hippocampus, and somatosensory cortex. 
  • The "error" signals subserving adaptive gain control in the primate vestibulo-ocular reflex. 
  • The Emerging Importance of the Cerebellum in Broad Risk for Psychopathology. 
  • The NPHP1 gene deletion associated with juvenile nephronophthisis is present in a subset of individuals with Joubert syndrome. 
  • The cerebellotectal pathway in the grey squirrel. 
  • The cerebellum influences vocal timing. 
  • The cerebellum: a neuronal learning machine? 
  • The cochlear nuclear complex: MR location and abnormalities. 
  • The effect of tremorine on dopamine concentration in the brain of the rat, guinea pig and rabbit. 
  • The index case for the fungal meningitis outbreak in the United States. 
  • The neural basis for motor learning in the vestibulo-ocular reflex in monkeys. 
  • The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2. 
  • The ontogeny and growth of the human tentorium cerebelli. 
  • The uptake of methyl mercury (203Hg) in different tissues related to its neurotoxic effects. 
  • Torticollis acquired in late infancy due to a cerebellar gangliocytoma. 
  • Toward a Neurocentric View of Learning. 
  • Trajectories of early brain volume development in fragile X syndrome and autism. 
  • Transcribing Memories in Genome Architecture. 
  • Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors. 
  • Transient postnatal elevation of norepinephrine content and turnover in brain regions of rats exposed to terbutaline prenatally: evidence for autoregulation of noradrenergic development? 
  • Transverse cerebellar diameter on cranial ultrasound scan in preterm neonates in an Australian population. 
  • Trophic control of the ornithine decarboxylase/polyamine system in neonatal rat brain regions: lesions caused by 6-hydroxydopamine produce effects selective for cerebellum. 
  • Turnover rates of amino acid neurotransmitters in regions of rat cerebellum. 
  • Twenty-four hour rhythms in the glycine content of rat hindbrain and spinal cord. 
  • Undernutrition and overnutrition in the neonatal rat: long-term effects on noradrenergic pathways in brain regions. 
  • Unity and diversity of tonic and phasic executive control components in episodic and working memory. 
  • Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380. 
  • Variation, signal, and noise in cerebellar sensory-motor processing for smooth-pursuit eye movements. 
  • Visual motion commands for pursuit eye movements in the cerebellum. 
  • Walker-Warburg syndrome. 
  • Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma. 
  • ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss. 
  • [3H]-flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: a multiple concentration autoradiographic study. 
  • [3H]dihydroergocryptine binding in rat brain. 
  • [Demonstration of a case of cerebellar tumor]. 
  • fMRI of the conscious rabbit during unilateral classical eyeblink conditioning reveals bilateral cerebellar activation. 
  • p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons. 
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  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Buckley, Anne Frances, Assistant Professor of Pathology, Pathology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Lisberger, Stephen, George Barth Geller Distinguished Professor for Research in Neurobiology, Neurobiology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Sommer, Marc A., W. H. Gardner, Jr. Associate Professor, Duke Science & Society
  • Turkington, Timothy Garvey, Associate Professor in Radiology, Radiology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology
  • Yan, Hai, Henry S. Friedman Distinguished Professor of Neuro-Oncology in the School of Medicine, Pathology