Cerebral Hemorrhage

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  Subject Areas on Research

  • A lethal association of congenital apnea with brainstem tegmental necrosis. 
  • A molecular genetic study of intracerebral hemorrhage. 
  • A randomized, controlled trial of platelet transfusions in thrombocytopenic premature infants. 
  • A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage. 
  • A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke. 
  • ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. 
  • Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence. 
  • Acute management of intracranial hemorrhage in patients receiving thrombolytic therapy: case reports. 
  • Age-related macular degeneration and long-term risk of stroke subtypes. 
  • Aggressiveness of care following intracerebral hemorrhage in women and men. 
  • Aneurysm rupture: lunar cycle, weather, atmospheric pressure, myth or reality? 
  • Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis. 
  • ApoE genotype and survival from intracerebral haemorrhage. 
  • Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans. 
  • Apolipoprotein E polymorphism and stroke in a population sample aged 75 years or more. 
  • Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia. 
  • Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage. 
  • Association Between Previous Use of Antiplatelet Therapy and Intracerebral Hemorrhage Outcomes. 
  • Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality. 
  • Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Behavioral equipoise: a way to resolve ethical stalemates in clinical research. 
  • Bone Marrow Mesenchymal Stem Cell Transplantation Increases GAP-43 Expression via ERK1/2 and PI3K/Akt Pathways in Intracerebral Hemorrhage. 
  • Bone marrow transplantation for sickle cell disease. 
  • Brain injury and ventricular dysfunction: insights into reversible heart failure. 
  • Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice. 
  • CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction. 
  • CT-guided epidural blood patching of directly observed or potential leak sites for the targeted treatment of spontaneous intracranial hypotension. 
  • Cellular reactions to subependymal plate haemorrhage in the human neonate. 
  • Central nervous system bleeding in hemophiliacs. 
  • Cerebellar hemorrhage as evaluated by computerized tomography. 
  • Cerebral hemorrhage and edema following brain biopsy in rats: significance of mean arterial blood pressure. 
  • Cerebral microbleeds and cognition: the epidemiology of dementia in Singapore study. 
  • Challenges in assessing hospital-level stroke mortality as a quality measure: comparison of ischemic, intracerebral hemorrhage, and total stroke mortality rates. 
  • Changes in brain biochemistry and oxygenation in the zone surrounding primary intracerebral hemorrhage. 
  • Changes in cerebral blood volume and cytochrome aa3 during hypertensive peaks in preterm infants. 
  • Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke. 
  • Churg-Strauss syndrome: an uncommon cause of intracerebral hemorrhage. 
  • Clevidipine rapidly and safely reduces blood pressure in acute intracerebral hemorrhage: the ACCELERATE trial. 
  • Clinical usefulness of a biomarker-based diagnostic test for acute stroke: the Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study. 
  • Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes. 
  • Contrast stasis on noncontrast computed tomography as a predictor of stroke postthrombolysis. 
  • Controversies in the management of brainstem cavernous angioma: report of two cases. 
  • Correlation of leukocytosis with early neurological deterioration following supratentorial intracerebral hemorrhage. 
  • Cost-effectiveness of prophylactic indomethacin in very-low-birth-weight infants. 
  • Creatine kinase brain isoenzyme: relationship of cerebrospinal fluid concentration to the neurologic condition of newborns and cellular localization in the human brain. 
  • Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage. 
  • De novo cerebral arteriovenous malformation: case report. 
  • Declining stroke mortality in young adults: hope and concern. 
  • Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators. 
  • Dural sinus thrombosis and venous infarction associated with antiphospholipid antibodies: MR findings. 
  • Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage. 
  • Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma. 
  • Elevated serum lactate correlates with intracranial hemorrhage in neonates treated with extracorporeal life support. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endovascular treatment of proximal and distal posterior inferior cerebellar artery aneurysms. 
  • Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage. 
  • Evaluation and treatment of patients with suspected normal pressure hydrocephalus on long-term warfarin anticoagulation therapy. 
  • Evaluation of neonatal intracranial hemorrhage by computerized tomography. 
  • Evaluation of the role of neurosurgical procedures in the pathogenesis of secondary brain-stem haemorrhages. 
  • Exploring the origins of echo-time-dependent quantitative susceptibility mapping (QSM) measurements in healthy tissue and cerebral microbleeds. 
  • Factors Considered by Clinicians when Prognosticating Intracerebral Hemorrhage Outcomes. 
  • Familial clustering of intracerebral hemorrhage: a prospective study in North Carolina. 
  • Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. 
  • Feasibility and applicability of paramedic-based prehospital fibrinolysis in a large North American center. 
  • First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina. 
  • Gender and age interact to affect early outcome after intracerebral hemorrhage. 
  • Gestational age at initiation of 17-alpha hydroxyprogesterone caproate and recurrent preterm birth. 
  • Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study. 
  • High-dose atorvastatin after stroke or transient ischemic attack. 
  • Histopathological changes in brain arteriovenous malformations after embolization using Onyx or N-butyl cyanoacrylate. Laboratory investigation. 
  • Hospitalization and case-fatality rates for stroke in Canada from 1982 through 1991. The Canadian Collaborative Study Group of Stroke Hospitalizations. 
  • Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition. 
  • Hyperammonemia in the ICU. 
  • Hypocarbia in the ventilated preterm infant and its effect on intraventricular haemorrhage and bronchopulmonary dysplasia. 
  • In-hospital outcomes of thrombolysis for acute ischemic stroke in patients with primary brain tumors. 
  • Incidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents: a comparison of TNK-tPA and rt-PA. 
  • Incidence of retinopathy of prematurity in the United States: 1997 through 2005. 
  • Incontinence and gait disturbance after intraventricular extension of intracerebral hemorrhage. 
  • Incorporating patient preferences into clinical trial design: results of the opinions of patients on treatment implications of new studies (OPTIONS) project. 
  • Influence of stroke subtype on quality of care in the Get With The Guidelines-Stroke Program. 
  • Infratentorial and supratentorial strokes after a cranioplasty. 
  • Insurance status and outcome after intracerebral hemorrhage: findings from Get With The Guidelines-stroke. 
  • Intracerebral hematoma in a hemophiliac. Combined surgical and factor VIII treatment. 
  • Intracerebral hemorrhage after carotid endarterectomy: incidence, contribution to neurologic morbidity, and predictive factors. 
  • Intracerebral hemorrhage after pipeline embolization: Management of antiplatelet agents and the case for point-of-care testing--case reports and review of literature. 
  • Intracerebral hemorrhage with hypothyroidism. 
  • Intracerebral malignant melanoma: high-field-strength MR imaging. 
  • Intracranial hemorrhage after coronary thrombolysis with tissue plasminogen activator. 
  • Intracranial hemorrhage risk and new thrombolytic therapies in acute myocardial infarction. 
  • Intrastriatal injection of autologous blood or clostridial collagenase as murine models of intracerebral hemorrhage. 
  • Intravenous tissue-type plasminogen activator therapy is an independent risk factor for symptomatic intracerebral hemorrhage after carotid endarterectomy. 
  • Intraventricular hemorrhage in blunt head trauma: an analysis of 43 cases. 
  • Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage. 
  • Lack of concordance between empirical scores and physician assessments of stroke and bleeding risk in atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. 
  • Letter by goldstein regarding article, "statins and intracerebral hemorrhage". 
  • Limitation of pulsatility index as a diagnostic tool in the newborn. 
  • Lipid profile, lipid-lowering medications, and intracerebral hemorrhage after tPA in get with the guidelines-stroke. 
  • Long-term improvement in outcome after intracerebral hemorrhage in patients treated with statins. 
  • MRI in hemiballismus due to subthalamic nucleus hemorrhage: an unusual complication of liver transplantation. 
  • Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes. 
  • Metastatic rhabdomyosarcoma presenting as intracranial hemorrhage: imaging findings. 
  • Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage. 
  • Necrotizing lymphoid vasculitis in X-linked lymphoproliferative syndrome. 
  • Neonatal complications after the administration of indomethacin for preterm labor. 
  • Neurodevelopmental outcome of infants with unilateral or bilateral periventricular hemorrhagic infarction. 
  • Neurodevelopmental outcome of survivors with posthemorrhagic hydrocephalus following Grade II neonatal intraventricular hemorrhage. 
  • Neurologic complications after allogeneic marrow transplantation for sickle cell anemia. 
  • Neurologic sequelae in the survivors of neonatal intraventricular hemorrhage. 
  • Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations. 
  • Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage. 
  • Neuroradiology case of the day. Enhancing calcified hematoma due to prior hypertensive bleed. 
  • Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: experience from the GUSTO-I trial. Global Utilization of Streptokinase and tissue-plasminogen activator (tPA) for Occluded Coronary Arteries. 
  • Nonimmune hydrops and hydrocephalus secondary to fetal intracranial hemorrhage. 
  • Obesity is associated with better survival and functional outcome after acute intracerebral hemorrhage. 
  • Ocular reactions in man from deep cerebellar stimulation and lesions. 
  • Off-hour admission and in-hospital stroke case fatality in the get with the guidelines-stroke program. 
  • Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature. 
  • PaCO2 in surfactant, positive pressure, and oxygenation randomised trial (SUPPORT). 
  • Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument. 
  • Perioperative morbidity and mortality in combined vs. staged approaches to carotid and coronary revascularization. 
  • Pharmacogenomic effects of apolipoprotein e on intracerebral hemorrhage. 
  • Preclinical models of intracerebral hemorrhage: a translational perspective. 
  • Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage. 
  • Predictors of late neurological deterioration after spontaneous intracerebral hemorrhage. 
  • Predictors of stroke in high-risk patients after acute myocardial infarction: insights from the VALIANT Trial. 
  • Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results. 
  • Primary hemorrhagic stroke in children with sickle cell disease is associated with recent transfusion and use of corticosteroids. 
  • Primum non nocere: antithombotics after intracerebral hemorrhage? 
  • Processed electroencephalogram during donation after cardiac death. 
  • Progesterone Improves Neurobehavioral Outcome in Models of Intracerebral Hemorrhage. 
  • Prolonged Cardiac Dysfunction After Intraparenchymal Hemorrhage and Neurogenic Stunned Myocardium. 
  • Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. 
  • Racial-ethnic disparities in acute blood pressure after intracerebral hemorrhage. 
  • Racial/Ethnic differences in process of care and outcomes among patients hospitalized with intracerebral hemorrhage. 
  • Radiologic intervention in the acute stroke patient. 
  • Relation of increased arterial blood pressure to mortality and stroke in the context of contemporary thrombolytic therapy for acute myocardial infarction. A randomized trial. GUSTO-I Investigators. 
  • Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes. 
  • Retinopathy and lobar intracerebral hemorrhage: insights into pathogenesis. 
  • Retinopathy of prematurity in the United States. 
  • Risk factors for in-hospital nonhemorrhagic stroke in patients with acute myocardial infarction treated with thrombolysis: results from GUSTO-I. 
  • Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator. 
  • Risks and Benefits Associated With Prestroke Antiplatelet Therapy Among Patients With Acute Ischemic Stroke Treated With Intravenous Tissue Plasminogen Activator. 
  • S100B and brain natriuretic peptide predict functional neurological outcome after intracerebral haemorrhage. 
  • Sequestration of amyloid beta-peptide. 
  • Sex and Age Interactions and Differences in Outcomes After Intracerebral Hemorrhage. 
  • Sex differences exist after intracerebral hemorrhage but may not affect outcome. 
  • Sex differences in incidence, pathophysiology, and outcome of primary intracerebral hemorrhage. 
  • Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative. 
  • Sex-Specific Effects of Progesterone on Early Outcome of Intracerebral Hemorrhage. 
  • Sonographic characteristics of small cerebral blood vessels. An in vivo and postmortem study. 
  • Spontaneous hemorrhage associated with a pilomyxoid astrocytoma. Case report. 
  • Statin therapy should be discontinued in patients with intracerebral hemorrhage. 
  • Statins after intracerebral hemorrhage: to treat or not to treat. 
  • Statins and poststroke intracerebral hemorrhage: Concern but increasing reassurance. 
  • Statins and the Risk of Intracerebral Hemorrhage in Patients With Previous Ischemic Stroke or Transient Ischemic Attack. 
  • Statins for stroke prevention. 
  • Stent-assisted coiling versus balloon remodeling of wide-neck aneurysms: comparison of angiographic outcomes. 
  • Streaking artifact reduction for quantitative susceptibility mapping of sources with large dynamic range. 
  • Stroke after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction: timing, characteristics, and clinical outcomes. 
  • Stroke after thrombolysis. Mortality and functional outcomes in the GUSTO-I trial. Global Use of Strategies to Open Occluded Coronary Arteries. 
  • Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. 
  • Sudden death due to undiagnosed T lymphoblastic leukemia/lymphoma in a 5-year-old boy. 
  • Surgical management of brainstem cavernomas: selection of approaches and microsurgical techniques. 
  • Systemic hemostasis with recombinant-activated factor VII followed by local thrombolysis with recombinant tissue plasminogen activator in intraventricular hemorrhage. 
  • T2 estimates in healthy and diseased brain tissue: a comparison using various MR pulse sequences. 
  • TT-301 inhibits microglial activation and improves outcome after central nervous system injury in adult mice. 
  • Ten-year results with the St. Jude Medical prosthesis. 
  • The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice. 
  • The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol. 
  • The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage. 
  • The association of rapid volume expansion and intraventricular hemorrhage in the preterm infant. 
  • The epidemiology, evaluation and treatment of stroke in adults with sickle cell disease. 
  • The new standing guideline committee policy of the American Stroke Association Stroke Council. 
  • The pathogenesis of secondary brainstem hemorrhages as studied in an experimental model. 
  • The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease. 
  • Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage-induced secondary brain injury and as potential targets for intervention. 
  • Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. 
  • Tissue factor in brain is not saturated with factor VIIa: implications for factor VIIa dosing in intracerebral hemorrhage. 
  • Treatment of sagittal sinus thrombosis associated with cerebral hemorrhage and intracranial hypertension. 
  • Tumor necrosis factor α antagonism improves neurological recovery in murine intracerebral hemorrhage. 
  • Ultrasound detection of brain damage in preterm infants. 
  • Ultrasound screening of premature infants: longitudinal follow-up of intracranial hemorrhage. 
  • Utility of Urgent Computed Tomography Angiography in the Setting of Intraparenchymal Brain Hemorrhage. 
  • Value of sonography in the diagnosis of intracranial hemorrhage and periventricular leukomalacia: a postmortem study of 35 cases. 
  • Value of sonography in the diagnosis of intracranial hemorrhage and periventricular leukomalacia: a postmortem study of 35 cases. 
  • Vascular lesions involving the cranial base: combined surgical and interventional radiologic approach. 
  • Xenon neuroprotection in experimental stroke: interactions with hypothermia and intracerebral hemorrhage. 
  • β-Blockers associated with no class-specific survival benefit in acute intracerebral hemorrhage. 
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  Keywords of People

  • Ehrlich, Matthew Evan, Assistant Professor of Neurology, Neurology, Stroke and Vascular Neurology
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology