Brain Ischemia

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  Subject Areas on Research

  • "Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke. 
  • 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. 
  • 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. 
  • A Double-Blind, Randomized, Placebo-Controlled Trial of Soluble Epoxide Hydrolase Inhibition in Patients with Aneurysmal Subarachnoid Hemorrhage. 
  • A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 
  • A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. 
  • A comparison of two stroke cohorts cared for by two different specialties in a practice-based tele-stroke population. 
  • A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. 
  • A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. 
  • A new in vivo method for quantitative analysis of stroke lesions using diffusion-weighted magnetic resonance microscopy. 
  • A novel genetic locus modulates infarct volume independently of the extent of collateral circulation. 
  • A pentapeptide monocyte locomotion inhibitory factor protects brain ischemia injury by targeting the eEF1A1/endothelial nitric oxide synthase pathway. 
  • A practical approach to CT angiography of the neck and brain. 
  • A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage. 
  • A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke. 
  • A simple, inexpensive method of monitoring brain temperature in conscious rodents. 
  • ACP Journal Club. In atrial fibrillation, the ATRIA risk score better predicted stroke than CHADS2 and CHA2DS2-VASc scores. 
  • Abciximab in acute ischemic stroke. A randomized, double-blind, placebo-controlled, dose-escalation study. 
  • Absence of July Phenomenon in Acute Ischemic Stroke Care Quality and Outcomes. 
  • Absence of selective deep white matter ischemia in chronic carotid disease. 
  • Absence of selective deep white matter ischemia in chronic carotid disease: a positron emission tomographic study of regional oxygen extraction. 
  • Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. 
  • Accuracy of ICD-9-CM coding for the identification of patients with acute ischemic stroke: effect of modifier codes. 
  • Acute Ischemic Stroke in Patients With COVID-19: An Analysis From Get With The Guidelines-Stroke. 
  • Acute Ischemic Stroke. 
  • Acute ischaemic stroke interventions: large vessel occlusion and beyond. 
  • Acute ischemic stroke treatment in 2007. 
  • Acute silent cerebral ischemic events in children with sickle cell anemia. 
  • Acute stroke imaging research roadmap. 
  • Additional Factors in Considering Patent Foramen Ovale Closure to Prevent Recurrent Ischemic Stroke. 
  • Adherence to Third European Cooperative Acute Stroke Study 3- to 4.5-hour exclusions and association with outcome: data from Get with the Guidelines-Stroke. 
  • Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study. 
  • Advances in primary stroke prevention. 
  • Age accounts for racial differences in ischemic stroke volume in a population-based study. 
  • An Outcome Model for Intravenous rt-PA in Acute Ischemic Stroke. 
  • An absolute measurement of brain water content using magnetic resonance imaging in two focal cerebral ischemic rat models. 
  • An optimal Wilcoxon-Mann-Whitney test of mortality and a continuous outcome. 
  • An update on the unfolded protein response in brain ischemia: Experimental evidence and therapeutic opportunities. 
  • Anesthesia in Experimental Stroke Research. 
  • Anesthetic effects on cerebral metabolic rate predict histologic outcome from near-complete forebrain ischemia in the rat. 
  • Anesthetic neuroprotection: antecedents and an appraisal of preclinical and clinical data quality. 
  • Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association). 
  • Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association). 
  • Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk. 
  • Anticoagulation Type and Early Recurrence in Cardioembolic Stroke: The IAC Study. 
  • Anticoagulation in Acute Neurological Disease. 
  • Antiphospholipid antibodies: findings at arteriography. 
  • Antiplatelet patterns and outcomes in patients with atrial fibrillation not prescribed an anticoagulant after stroke. 
  • Antiplatelet therapy in patients with atrial fibrillation: a systematic review and meta-analysis of randomized trials. 
  • Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial. 
  • Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician. 
  • Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis. 
  • Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse. 
  • Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. 
  • Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia. 
  • Appearance of Meningovascular Neurosyphilis Causing an Acute Ischemic Stroke. 
  • Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial. 
  • Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome. 
  • Assessment and provision of rehabilitation among patients hospitalized with acute ischemic stroke in China: Findings from the China National Stroke Registry II. 
  • Assessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries. 
  • Assessment of the patient with hyperacute stroke: imaging and therapy. 
  • Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke. 
  • Association between age and outcomes following thrombectomy for anterior circulation emergent large vessel occlusion is determined by degree of recanalisation. 
  • Association between estimated glomerular filtration rate and clinical outcomes in patients with acute ischaemic stroke: results from China National Stroke Registry. 
  • Association between stroke center hospitalization for acute ischemic stroke and mortality. 
  • Association of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke. 
  • Association of Kidney Function With 30-Day and 1-Year Poststroke Mortality and Hospital Readmission. 
  • Association of Race With Mortality and Cardiovascular Events in a Large Cohort of US Veterans. 
  • Association of body mass index with mortality and functional outcome after acute ischemic stroke. 
  • Association of measured platelet reactivity with changes in P2Y12 receptor inhibitor therapy and outcomes after myocardial infarction: Insights into routine clinical practice from the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) study. 
  • Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study. 
  • Associations of Medicaid Expansion With Access to Care, Severity, and Outcomes for Acute Ischemic Stroke. 
  • Astroglial acid-base dynamics in hyperglycemic and normoglycemic global ischemia. 
  • Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Autoregulation after ischaemic stroke. 
  • Average Temperature, Diurnal Temperature Variation, and Stroke Hospitalizations. 
  • B-type natriuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: insights from the Acute Decompensated Heart Failure National Registry. 
  • Barbiturate-induced coma to protect against cerebral ischemia and increased intracranial pressure. 
  • Barotrauma and air embolism in hyperbaric oxygen therapy. 
  • Baseline NIH Stroke Scale is an inferior predictor of functional outcome in the era of acute stroke intervention. 
  • Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations. 
  • Blockade of the extracellular signal-regulated kinase pathway by U0126 attenuates neuronal damage following circulatory arrest. 
  • Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial. 
  • Blood Pressure Goals and Clinical Outcomes after Successful Endovascular Therapy: A Multicenter Study. 
  • Blood pressure and in-hospital outcomes in patients presenting with ischaemic stroke. 
  • Blood pressure management in patients with acute ischemic stroke. 
  • Bone morphogenetic protein 10: a novel risk marker of ischaemic stroke in patients with atrial fibrillation. 
  • Brain resuscitation. Medical management and innovations. 
  • CT perfusion-guided versus time-guided mechanical recanalization in acute ischemic stroke patients. 
  • Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. 
  • Cardiac Biomarkers Predict Large Vessel Occlusion in Patients with Ischemic Stroke. 
  • Carotid Endarterectomy to Remove Retained Solitaire Stent Retriever inside Carotid Stent after Mechanical Thrombectomy. 
  • Carotid Stenosis and Recurrent Ischemic Stroke: A Post-Hoc Analysis of the POINT Trial. 
  • Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults. 
  • Causal relationship between neuronal activity and cerebral hemodynamics in patients with ischemic stroke. 
  • Causes and Risk Factors of Cerebral Ischemic Events in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention. 
  • Cellular regulation of the benzodiazepine/GABA receptor: arachidonic acid, calcium, and cerebral ischemia. 
  • Cerebral autoregulation following minor head injury. 
  • Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans. 
  • Cerebral hemodynamics in ischemic cerebrovascular disease. 
  • Cerebral ischemia/stroke and small ubiquitin-like modifier (SUMO) conjugation--a new target for therapeutic intervention? 
  • Cerebrovascular Physiology During Pediatric Extracorporeal Membrane Oxygenation: A Multicenter Study Using Transcranial Doppler Ultrasonography. 
  • Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhage. 
  • Challenges in assessing hospital-level stroke mortality as a quality measure: comparison of ischemic, intracerebral hemorrhage, and total stroke mortality rates. 
  • Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: effect of diazepam. 
  • Characteristics of strokes associated with centrifugal flow left ventricular assist devices. 
  • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. 
  • Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus. 
  • Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke. 
  • Chronic kidney disease and bleeding complications after intravenous thrombolytic therapy for acute ischemic stroke. 
  • Chronic kidney disease and risk for cardiovascular and limb outcomes in patients with symptomatic peripheral artery disease: The EUCLID trial. 
  • Chronic kidney disease and stroke. 
  • Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study. 
  • Clinical Reasoning: Two see or not two see-Is it really double vision? 
  • Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression. 
  • Clinical characteristics of myocardial stunning in acute stroke. 
  • Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial. 
  • Clinical preventive practice. 
  • Clinical usefulness of a biomarker-based diagnostic test for acute stroke: the Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study. 
  • Clinical utility of echocardiography in secondary ischemic stroke prevention. 
  • Clinically relevant reperfusion in acute ischemic stroke: MTT performs better than Tmax and TTP. 
  • Clopidogrel and aspirin after ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis of randomized clinical trials. 
  • Coexistent Sickle Cell Disease Has No Impact on the Safety or Outcome of Lytic Therapy in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke. 
  • Common Data Elements for Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Working Group on Hospital Course and Acute Therapies-Proposal of a Multidisciplinary Research Group. 
  • Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats. 
  • Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity. 
  • Comparison of Acute Ischemic Stroke Care and Outcomes Between Comprehensive Stroke Centers and Primary Stroke Centers in the United States. 
  • Comparison of Clinical Care and In-Hospital Outcomes of Asian American and White Patients With Acute Ischemic Stroke. 
  • Comparison of Outcomes of Ischemic Stroke Initially Imaged With Cranial Computed Tomography Alone vs Computed Tomography Plus Magnetic Resonance Imaging. 
  • Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care. 
  • Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion. 
  • Complications of Intravenous Tenecteplase Versus Alteplase for the Treatment of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. 
  • Components and Trends in Door to Treatment Times for Endovascular Therapy in Get With The Guidelines-Stroke Hospitals. 
  • Computed tomography perfusion-based selection of patients for endovascular recanalization. 
  • Contemporary trends and predictors of postacute service use and routine discharge home after stroke. 
  • Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction. 
  • Correlation of serum brain natriuretic peptide with hyponatremia and delayed ischemic neurological deficits after subarachnoid hemorrhage. 
  • Corticospinal tract lesion load: An imaging biomarker for stroke motor outcomes. 
  • Cost efficiency of anticoagulation with warfarin to prevent stroke in medicare beneficiaries with nonvalvular atrial fibrillation. 
  • Cost-effectiveness of antiplatelet agents in secondary stroke prevention: the limits of certainty. 
  • Count-based PET method for predicting ischemic stroke in patients with symptomatic carotid arterial occlusion. 
  • Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo. 
  • Data Do Not Support Selection by Target Perfusion Mismatch of Patients for Endovascular Stroke Treatment Within the 16- to 24-Hour Interval. 
  • Death and rehospitalization after transient ischemic attack or acute ischemic stroke: one-year outcomes from the adherence evaluation of acute ischemic stroke-longitudinal registry. 
  • Declining stroke mortality in young adults: hope and concern. 
  • Decompressive hemicraniectomy in pediatric patients with malignant middle cerebral artery infarction: case series and review of the literature. 
  • Defining the ischemic penumbra using magnetic resonance oxygen metabolic index. 
  • Degradation of spectrin and ankyrin in the ischemic rat kidney. 
  • Delay between stroke onset and emergency department evaluation. 
  • Delays in Door-to-Needle Times and Their Impact on Treatment Time and Outcomes in Get With The Guidelines-Stroke. 
  • Detection of Atrial Fibrillation After Central Retinal Artery Occlusion. 
  • Diabetes and long-term outcomes of ischaemic stroke: findings from Get With The Guidelines-Stroke. 
  • Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia. 
  • Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum. 
  • Differences in Acute Ischemic Stroke Quality of Care and Outcomes by Primary Stroke Center Certification Organization. 
  • Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System. 
  • Differential Risk Factors and Outcomes of Ischemic Stroke due to Cervical Artery Dissection in Young Adults. 
  • Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment. 
  • Differing associations of white matter lesions and lacunar infarction with retinal microvascular signs. 
  • Diffusional Kurtosis Imaging and Motor Outcome in Acute Ischemic Stroke. 
  • Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice. 
  • Disparities in Inter-hospital Helicopter Transportation for Hispanics by Geographic Region: A Threat to Fairness in the Era of Thrombectomy. 
  • Distinguishing Arterial Ischemic Stroke From Hypoxic-Ischemic Encephalopathy in the Neonate at Birth. 
  • Does diffusion-weighted imaging represent the ischemic core? An evidence-based systematic review. 
  • Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative. 
  • Dual antiplatelet therapy in aneurysmal subarachnoid hemorrhage: association with reduced risk of clinical vasospasm and delayed cerebral ischemia. 
  • Dysphagia screening and hospital-acquired pneumonia in patients with acute ischemic stroke: findings from Get with the Guidelines--Stroke. 
  • Early Elevated Troponin Levels After Ischemic Stroke Suggests a Cardioembolic Source. 
  • Early biomarkers of stroke. 
  • Early changes of tissue perfusion after tissue plasminogen activator in hyperacute ischemic stroke. 
  • Early ischaemic and haemorrhagic complications after atrial fibrillation-related ischaemic stroke: analysis of the IAC study. 
  • Early recurrent ischemic stroke. A case-control study. 
  • Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin. 
  • Echocardiography for the detection of cardiac sources of embolism in patients with stroke or transient ischemic attack. 
  • Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial. 
  • Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage. 
  • Effect of Known Atrial Fibrillation and Anticoagulation Status on the Prehospital Identification of Large Vessel Occlusion. 
  • Effect of a Multifaceted Quality Improvement Intervention on Hospital Personnel Adherence to Performance Measures in Patients With Acute Ischemic Stroke in China: A Randomized Clinical Trial. 
  • Effect of alirocumab on cardiovascular outcomes after acute coronary syndromes according to age: an ODYSSEY OUTCOMES trial analysis. 
  • Effect of continuous infusion of asialoerythropoietin on short-term changes in infarct volume, penumbra apoptosis and behaviour following middle cerebral artery occlusion in rats. 
  • Effect of dual versus mono antiplatelet therapy on recurrent stroke modulated by activated partial thromboplastin time. 
  • Effect of intracerebral norepinephrine depletion on outcome from severe forebrain ischemia in the rat. 
  • Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage. 
  • Effects of Long-Term Vagus Nerve Electrical Stimulation Therapy on Acute Cerebral Infarction and Neurological Function Recovery in Post MCAO Mice. 
  • Effects of a synthetic allosteric modifier of hemoglobin oxygen affinity on outcome from global cerebral ischemia in the rat. 
  • Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat. 
  • Effects of isoflurane, ketamine, and fentanyl/N2O on concentrations of brain and plasma catecholamines during near-complete cerebral ischemia in the rat. 
  • Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia. 
  • Effects of transient forebrain ischemia in area CA1 of the gerbil hippocampus: an in vitro study. 
  • Electroencephalographic burst suppression is not required to elicit maximal neuroprotection from pentobarbital in a rat model of focal cerebral ischemia. 
  • Elevated brain lesion volumes in older adults who use calcium supplements: a cross-sectional clinical observational study. 
  • Emergency department adherence to American Heart Association guidelines for blood pressure management in acute ischemic stroke. 
  • Emergency medical service hospital prenotification is associated with improved evaluation and treatment of acute ischemic stroke. 
  • Emergency medical services use and its association with acute ischaemic stroke evaluation and treatment in Singapore. 
  • Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone. 
  • Endothelial microparticle levels are similar in acute ischemic stroke and stroke mimics due to activation and not apoptosis/necrosis. 
  • EndothelinA receptor antagonist BSF-208075 causes immune modulation and neuroprotection after stroke in gerbils. 
  • Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis. 
  • Endovascular Thrombectomy for Pediatric Acute Ischemic Stroke. 
  • Endovascular intervention for acute ischemic stroke in light of recent trials. 
  • Endovascular management of acute large vessel occlusion stroke in pregnancy is safe and feasible. 
  • Endovascular repair of an acute symptomatic carotid artery dissection through the false dissecting carotid lumen. 
  • Endovascular stroke intervention in the very young. 
  • Endovascular stroke intervention in young patients with large vessel occlusions. 
  • Estimated incidence of previously undetected atrial fibrillation on a 14-day continuous electrocardiographic monitor and associated risk of stroke. 
  • Evidence-Based Performance Measures and Outcomes in Patients With Acute Ischemic Stroke. 
  • Evolving role of biomarkers in acute cerebrovascular disease. 
  • Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat. 
  • Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease. 
  • Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial. 
  • Extracranial-intracranial bypass for ischemic cerebrovascular disease: what have we learned from the Carotid Occlusion Surgery Study? 
  • Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial. 
  • Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects. 
  • Factors associated with therapeutic anticoagulation status in patients with ischemic stroke and atrial fibrillation. 
  • Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke. 
  • First Food and Drug Administration-approved prospective trial of primary intracranial stenting for acute stroke: SARIS (stent-assisted recanalization in acute ischemic stroke). 
  • Fourth down and five. 
  • Frequency of various brain parenchymal findings of early cerebral ischemia on unenhanced CT scans. 
  • Ganglioside GM1 in acute ischemic stroke. The SASS Trial. 
  • Generalizations about general anesthesia: the unsubstantiated condemnation of general anesthesia for patients undergoing intra-arterial therapy for anterior circulation stroke. 
  • Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease. 
  • Geographic variation in one-year recurrent ischemic stroke rates for elderly Medicare beneficiaries in the USA. 
  • Guideline-directed low-density lipoprotein management in high-risk patients with ischemic stroke: findings from Get with the Guidelines-Stroke 2003 to 2012. 
  • Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. 
  • Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. 
  • Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. 
  • Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update a scientific statement from the Stroke Council of the American Heart Association/American Stroke Association. 
  • Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association. 
  • Haemiballism/haemichorea: an atypical presentation of ischaemic stroke. 
  • Halothane reduces focal ischemic injury in the rat when brain temperature is controlled. 
  • Have randomized controlled trials of neuroprotective drugs been underpowered? An illustration of three statistical principles. 
  • Healthcare Resource Availability, Quality of Care, and Acute Ischemic Stroke Outcomes. 
  • Hemodynamic effects of middle cerebral artery stenosis and occlusion. 
  • Hemodynamics and metabolism in ischemic cerebrovascular disease. 
  • Hemostasis and alterations of the central nervous system. 
  • High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat. 
  • High-resolution vessel wall imaging after mechanical thrombectomy. 
  • Hormone replacement therapy and ischemic stroke severity in women: a case-control study. 
  • Hospital Quality Metrics: "America's Best Hospitals" and Outcomes After Ischemic Stroke. 
  • Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research). 
  • Hospital arrival time and intravenous t-PA use in US Academic Medical Centers, 2001-2004. 
  • Hospital-level variation in mortality and rehospitalization for medicare beneficiaries with acute ischemic stroke. 
  • Human hypoxia and seizures: effects and interactions. 
  • Hydrogen peroxide production by monoamine oxidase during ischemia-reperfusion in the rat brain. 
  • Hyperoxia-induced brain ischemia: the Strawman comes up short. 
  • Hypertensive retinopathy and risk of stroke. 
  • Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage. 
  • Hypothermia and cerebral protection strategies in aortic arch surgery: a comparative effectiveness analysis from the STS Adult Cardiac Surgery Database. 
  • Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain. 
  • IV tPA for acute ischemic stroke: Times are changing. 
  • Imaging preventable infarction in patients with acute ischemic stroke. 
  • Impact of Insurance Status on Outcomes and Use of Rehabilitation Services in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke. 
  • Impact of comorbidities on ischemic stroke outcomes in women. 
  • Impaired capacity to restore proteostasis in the aged brain after ischemia: Implications for translational brain ischemia research. 
  • Impaired firing and sodium channel function in CA1 hippocampal interneurons after transient cerebral ischemia. 
  • Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative. 
  • Improving patient selection for coagulopathy testing in the setting of acute ischemic stroke. 
  • In Reply: Tirofiban Protocol Protects Against Delayed Cerebral Ischemia: A Case-Series Study. 
  • In vivo models of cerebral ischemia: effects of parenterally administered NMDA receptor glycine site antagonists. 
  • In-hospital outcomes of thrombolysis for acute ischemic stroke in patients with primary brain tumors. 
  • Inability to Consent Does Not Diminish the Desirability of Stroke Thrombolysis 
  • Inaccuracy of the ICD-9-CM in identifying the diagnosis of ischemic cerebrovascular disease. 
  • Inaccuracy of the ICD-9-CM in identifying the diagnosis of ischemic cerebrovascular disease. 
  • Inaccuracy of the International Classification of Diseases (ICD-9-CM) in identifying the diagnosis of ischemic cerebrovascular disease. 
  • Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques. 
  • Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome. 
  • Increasing O-GlcNAcylation is neuroprotective in young and aged brains after ischemic stroke. 
  • Incremental prognostic value of renal function for stroke prediction in atrial fibrillation. 
  • Inherited thrombophilia in childhood arterial stroke: data from Lebanon. 
  • Inhibition of nitric oxide synthase increases extracellular cerebral glutamate concentration after global ischemia. 
  • Inpatient costs of specific cerebrovascular events at five academic medical centers. 
  • Intensity of statin treatment after acute coronary syndrome, residual risk, and its modification by alirocumab: insights from the ODYSSEY OUTCOMES trial. 
  • Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes. 
  • Interactions between hypothermia and the latency to ischemic depolarization: implications for neuroprotection. 
  • International Comparison of Patient Characteristics and Quality of Care for Ischemic Stroke: Analysis of the China National Stroke Registry and the American Heart Association Get With The Guidelines--Stroke Program. 
  • International normalized ratio control and subsequent clinical outcomes in patients with atrial fibrillation using warfarin. 
  • Intra-arterial Thrombolysis for Acute Retinal Ischemia: A Retrospective, Observational, Cohort Study. 
  • Intra-arterial therapies for acute ischemic stroke: unsafe and without proven value. 
  • Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke. 
  • Intracellular monitoring of experimental respiratory failure. Collaborative Group on Intracellular Monitoring. 
  • Intraoperative hyperglycemia and cognitive decline after CABG. 
  • Intravenous Alteplase for Mild Nondisabling Acute Ischemic Stroke: A Bridge Too Far? 
  • Intravenous Tissue Plasminogen Activator in Stroke Mimics. 
  • Intravenous Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Patients With History of Stroke Plus Diabetes Mellitus. 
  • Intravenous tPA (Tissue-Type Plasminogen Activator) in Patients With Acute Ischemic Stroke Taking Non-Vitamin K Antagonist Oral Anticoagulants Preceding Stroke. 
  • Intravenous thrombolysis of basilar artery thrombosis. 
  • Inverse National Trends in Decompressive Craniectomy versus Endovascular Thrombectomy for Stroke. 
  • Investigating the mechanisms of perioperative ischemic stroke in the Carotid Occlusion Surgery Study. 
  • Is Risk-Standardized In-Hospital Stroke Mortality an Adequate Proxy for Risk-Standardized 30-Day Stroke Mortality Data? Findings From Get With The Guidelines-Stroke. 
  • Is age a key factor contributing to the disparity between success of neuroprotective strategies in young animals and limited success in elderly stroke patients? Focus on protein homeostasis. 
  • Is diabetic retinopathy an independent risk factor for ischemic stroke? 
  • Is routine retinal examination useful in patients with acute ischemic stroke? 
  • Is there a period of liability with initiation of warfarin in patients with atrial fibrillation? 
  • Ischaemic stroke in heart failure: back to basics? 
  • Ischemia contributes to adverse effects of cocaine on brain development: suppression of ornithine decarboxylase activity in neonatal rat. 
  • Ischemic Stroke Transfer Patterns in the Northeast United States. 
  • Ischemic Stroke and Internal Carotid Artery Web. 
  • Ischemic Stroke with Troponin Elevation: Patient Characteristics, Resource Utilization, and In-Hospital Outcomes. 
  • Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage. 
  • Ischemic stroke because of intracranial fibromuscular dysplasia. 
  • Ischemic stroke in COVID-19-positive patients: an overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist. 
  • Ischemic stroke: "acidotoxicity" is a perpetrator. 
  • Isoflurane provides long-term protection against focal cerebral ischemia in the rat. 
  • JURaSSiC: accuracy of clinician vs risk score prediction of ischemic stroke outcomes. 
  • Joining a Multicenter Clinical Trial. 
  • LDL-C levels, lipid-lowering treatment and recurrent stroke in minor ischaemic stroke or TIA. 
  • Lack of concordance between empirical scores and physician assessments of stroke and bleeding risk in atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. 
  • Lack of correlation between pattern of collateralization and misery perfusion in patients with carotid occlusion. 
  • Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat. 
  • Large-dose infusions of heparinoid ORG 10172 in ischemic stroke. 
  • Left Atrial Appendage Morphology and Embolic Stroke of Undetermined Source: A Cross-Sectional Multicenter Pilot Study. 
  • Level of consciousness at discharge and associations with outcome after ischemic stroke. 
  • Lipid profile, lipid-lowering medications, and intracerebral hemorrhage after tPA in get with the guidelines-stroke. 
  • Lipids in high-risk patients presenting with ischemic stroke or transient ischemic attack: are we missing the target? 
  • Long-Term Prognostic Implications of Previous Silent Myocardial Infarction in Patients Presenting With Acute Myocardial Infarction. 
  • Longitudinal fMRI study of language recovery after a left hemispheric ischemic stroke. 
  • Low-dose rivaroxaban and aspirin among patients with peripheral artery disease: a meta-analysis of the COMPASS and VOYAGER trials. 
  • Low-dose rivaroxaban plus aspirin in older patients with peripheral artery disease undergoing acute limb revascularization: insights from the VOYAGER PAD trial. 
  • Lower incidence of vascular events following small artery ischemic stroke. 
  • Lower stroke risk with lower blood pressure in hemodynamic cerebral ischemia. 
  • MCA flow asymmetry is a marker for cerebrovascular disease. 
  • MR DWI does not substitute for stroke severity scores in predicting stroke outcome. 
  • MR imaging of oxygen extraction and neurovascular coupling. 
  • Magnesium neuroprotection is limited in humans with acute brain injury. 
  • Magnetic resonance microscopy--a new tool for the toxicologic pathologist. 
  • Mechanical Thrombectomy in Distal Vessels: Revascularization Rates, Complications, and Functional Outcome. 
  • Mechanical Thrombectomy in Ischemic Stroke Patients with Severe Pre-Stroke Disability. 
  • Mechanical thrombectomy for perioperative ischemic stroke following elective inpatient surgery in the United States. 
  • Mechanism of detection of acute cerebral ischemia in rats by diffusion-weighted magnetic resonance microscopy. 
  • Medical comorbidity in late-life depression. 
  • Medical therapy for acute ischemic stroke. 
  • Medicare HMO penetration and mortality outcomes of ischemic stroke. 
  • Medicare Shared Savings ACOs and Hospice Care for Ischemic Stroke Patients. 
  • Medicare claims indicators of healthcare utilization differences after hospitalization for ischemic stroke: Race, gender, and caregiving effects. 
  • Medicine. Stroke--tPA and the clinic. 
  • Mice overexpressing extracellular superoxide dismutase have increased resistance to global cerebral ischemia. 
  • Microvascular structure and network in the retina of patients with ischemic stroke. 
  • Middle Cerebral Artery Residual Contrast Stagnation on Noncontrast CT Scan Following Endovascular Treatment in Acute Ischemic Stroke Patients. 
  • Middle cerebral artery velocity during upright posture after marijuana smoking. 
  • Modern medical management of acute ischemic stroke. 
  • Monitoring and improving acute stroke care: The North Carolina Stroke Care Collaborative. 
  • Monte Carlo Simulation Modeling of a Regional Stroke Team's Use of Telemedicine. 
  • Mortality Following Cardiovascular and Bleeding Events Occurring Beyond 1 Year After Coronary Stenting: A Secondary Analysis of the Dual Antiplatelet Therapy (DAPT) Study. 
  • Moyamoya vasculopathy in a child after hemolytic uremic syndrome: a possible etiopathogenesis. 
  • N-methyl-D-aspartate receptor-dependent denitrosylation of neuronal nitric oxide synthase increase the enzyme activity. 
  • National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. 
  • National surveillance of stroke quality of care and outcomes by applying post-stratification survey weights on the Get With The Guidelines-Stroke patient registry. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke. 
  • Neurological picture. Mimetic smile. 
  • Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice. 
  • Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia. 
  • Neuroprotection by N-methyl-D-aspartate antagonists in focal cerebral ischemia is dependent on continued maintenance dosing. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotective effect of NMDA receptor glycine recognition site antagonism persists when brain temperature is controlled. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • Neuropsychological correlates of magnetic resonance imaging-defined subcortical ischemic depression. 
  • No reduction in cerebral metabolism as a result of early moderate hyperventilation following severe traumatic brain injury. 
  • Nonocclusion and spontaneous recanalization rates in acute ischemic stroke: a review of cerebral angiography studies. 
  • Nonstenotic carotid plaques: Stroke causation or guilt by association? 
  • Novel diagnostic test for acute stroke. 
  • O-linked β-N-acetylglucosamine modification of proteins is activated in post-ischemic brains of young but not aged mice: Implications for impaired functional recovery from ischemic stress. 
  • Off-hour admission and in-hospital stroke case fatality in the get with the guidelines-stroke program. 
  • Optimization of perfusion imaging for acute cerebral ischemia: review of recent clinical trials and recommendations for future studies. 
  • Oral Anticoagulation and Adverse Outcomes after Ischemic Stroke in Heart Failure Patients without Atrial Fibrillation. 
  • Oral anticoagulant therapy for the prevention of stroke. 
  • Osteopontin expression during early cerebral ischemia-reperfusion in rats: enhanced expression in the right cortex is suppressed by acetaminophen. 
  • Outcomes After Endovascular Thrombectomy With or Without Alteplase in Routine Clinical Practice. 
  • Outcomes after ischemic stroke for hospitals with and without Joint Commission-certified primary stroke centers. 
  • Outcomes in mild or rapidly improving stroke not treated with intravenous recombinant tissue-type plasminogen activator: findings from Get With The Guidelines-Stroke. 
  • Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD2 score. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative Stress and Total Antioxidant Status During Internal Carotid Artery Clamping with or without Shunting: An Experimental Pilot Study. 
  • Oxygen metabolism in acute ischemic stroke. 
  • P2Y12 receptor inhibitors for secondary prevention of ischemic stroke. 
  • PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis. 
  • PET screening of carotid occlusion. 
  • Panel of biomarkers predicts stroke. 
  • Pathophysiology and Risk of Atrial Fibrillation Detected after Ischemic Stroke (PARADISE): A Translational, Integrated, and Transdisciplinary Approach. 
  • Pathophysiology of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Review. 
  • Patient safety in trials of therapy for acute ischemic stroke. 
  • Patients living in impoverished areas have more severe ischemic strokes. 
  • Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors. 
  • Pearls & Oy-sters: multiple ischemic strokes secondary to heparin-induced thrombocytopenia. 
  • Pearls & Oy-sters: polycythemia vera presenting with ischemic strokes in multiple arterial territories. 
  • Penumbra Consumption Rates Based on Time-to-Maximum Delay and Reperfusion Status: A Post Hoc Analysis of the DEFUSE 3 Trial. 
  • Perception Versus Actual Performance in Timely Tissue Plasminogen Activation Administration in the Management of Acute Ischemic Stroke. 
  • Performing cost-effectiveness analysis by integrating randomized trial data with a comprehensive decision model: application to treatment of acute ischemic stroke. 
  • Perfusion CT compared to H(2) (15)O/O (15)O PET in patients with chronic cervical carotid artery occlusion. 
  • Periischemic cerebral blood flow (CBF) does not explain beneficial effects of isoflurane on outcome from near-complete forebrain ischemia in rats. 
  • Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients. 
  • Phase 1/2a Trial of ISPASM. 
  • Physician prescribing patterns following hospital admission for ischemic cerebrovascular disease. 
  • Physiological responses to focal cerebral ischemia in humans. 
  • Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study. 
  • Poor performance of stroke prognostication using Age and National Institutes of Health Stroke Scale-100 to predict 3- and 12-month outcomes of ischemic stroke in China National Stroke Registry. 
  • Positron emission tomography and its application to the study of cerebrovascular disease in man. 
  • Post-ischemia common carotid artery occlusion worsens memory loss, but not sensorimotor deficits, in long-term survived stroke mice. 
  • Postischemic diazepam is neuroprotective in the gerbil hippocampus. 
  • Postischemic synaptic excitation and N-methyl-D-aspartate receptor activation in gerbils. 
  • Postischemic synaptic physiology of CA1 hippocampal pyramidal cells. 
  • Predicting symptomatic intracranial haemorrhage after mechanical thrombectomy: the TAG score. 
  • Predictors of Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage with Asymptomatic Angiographic Vasospasm on Admission. 
  • Predictors of symptomatic intracranial haemorrhage in patients with an ischaemic stroke with neurological deterioration after intravenous thrombolysis. 
  • Preoperative risk factors for carotid endarterectomy. 
  • Preservation of structural brain network hubs is associated with less severe post-stroke aphasia. 
  • Prevalence and Predictors of Gastrostomy Tube and Tracheostomy Placement in Anoxic/Hypoxic Ischemic Encephalopathic Survivors of In-Hospital Cardiopulmonary Resuscitation in the United States. 
  • Prevalence and Prognostic Significance of Left Ventricular Noncompaction in Patients Referred for Cardiac Magnetic Resonance Imaging. 
  • Preventable readmissions within 30 days of ischemic stroke among Medicare beneficiaries. 
  • Preventing ischemic stroke in patients with prior stroke and transient ischemic attack : a statement for healthcare professionals from the Stroke Council of the American Heart Association. 
  • Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. 
  • Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. 
  • Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. 
  • Prior Antithrombotic Use Is Associated With Favorable Mortality and Functional Outcomes in Acute Ischemic Stroke. 
  • Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/NMDA antagonist: an in vivo three-dimensional diffusion-weighted MR microscopy study. 
  • Progression of subcortical ischemic disease from vascular depression to vascular dementia. 
  • Prolonged Cardiac Rhythm Monitoring and Secondary Stroke Prevention in Patients With Cryptogenic Cerebral Ischemia. 
  • Proposed high-risk screening protocol for Fabry disease in patients with renal and vascular disease. 
  • Prospective acute ischemic stroke outcomes after endovascular therapy: a real-world experience. 
  • Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cell cultures. 
  • Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. 
  • Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack: Findings From Get With The Guidelines-Stroke. 
  • Quality of care and outcomes for in-hospital ischemic stroke: findings from the National Get With The Guidelines-Stroke. 
  • Quantitative proton magnetic resonance imaging in focal cerebral ischemia in rat brain. 
  • RIP3 S-nitrosylation contributes to cerebral ischemic neuronal injury. 
  • Race-Ethnic Disparities in Rates of Declination of Thrombolysis for Stroke. 
  • Race/Ethnic differences in the risk of hemorrhagic complications among patients with ischemic stroke receiving thrombolytic therapy. 
  • Racial and ethnic differences in outcomes in older patients with acute ischemic stroke. 
  • Racial differences in mortality among patients with acute ischemic stroke: an observational study. 
  • Racial variations in ischemic stroke-related physical and functional impairments. 
  • Racial variations in the rates of carotid angiography and endarterectomy in patients with stroke and transient ischemic attack. 
  • Radiologic intervention in the acute stroke patient. 
  • Rapid change in prescribing behavior in hospitals participating in get with the guidelines-stroke after release of the management of atherothrombosis with clopidogrel in high-risk patients (MATCH) clinical trial results. 
  • Rationale and design of ApoA-I Event Reducing in Ischemic Syndromes II (AEGIS-II): A phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to investigate the efficacy and safety of CSL112 in subjects after acute myocardial infarction. 
  • Rationale and design of a cluster-randomized multifaceted intervention trial to improve stroke care quality in China: The GOLDEN BRIDGE-Acute Ischemic Stroke. 
  • Rationale and design of a stepped wedge cluster randomised trial to improve acute reperfusion treatment quality for stroke: IMPROVE stroke care in China. 
  • Reader response: Optimizing in-hospital triage for large vessel occlusion using a novel clinical scale (GAI2AA). 
  • Reader response: The dimension of preventable stroke in a large representative patient cohort. 
  • Recent Myocardial Infarction is Associated With Increased Risk in Older Adults With Acute Ischemic Stroke Receiving Thrombolytic Therapy. 
  • Recombinant adenoviral expression of dominant negative IkappaBalpha protects brain from cerebral ischemic injury. 
  • Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. 
  • Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study. 
  • Redefining Early Neurological Improvement After Reperfusion Therapy in Stroke. 
  • Regional CBF in apolipoprotein E-deficient and wild type mice during focal cerebral ischemia. 
  • Regional Variation in 30-Day Ischemic Stroke Outcomes for Medicare Beneficiaries Treated in Get With The Guidelines-Stroke Hospitals. 
  • Relationship between hospital performance measures and outcomes in patients with acute ischaemic stroke: a prospective cohort study. 
  • Relationship between physician specialty and the selection and outcome of ischemic stroke patients. 
  • Renal Dysfunction and In-Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy. 
  • Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue. 
  • Repetitive intraperitoneal caspase-3 inhibitor and anesthesia reduces neuronal damage. 
  • Reply to effect of CYP2C19*2 and *3 on clinical outcome in ischemic stroke patients treated with Clopidogrel. 
  • Representativeness of the Get With The Guidelines-Stroke Registry: comparison of patient and hospital characteristics among Medicare beneficiaries hospitalized with ischemic stroke. 
  • Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. 
  • Response by Powers and Rabinstein to Letter Regarding Article, "2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association". 
  • Response to Letter Regarding Article, "Association of Race With Mortality and Cardiovascular Events in a Large Cohort of US Veterans". 
  • Response to Letter Regarding Article, "Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis". 
  • Responses to the 10 most frequently asked questions about perfusion CT. 
  • Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes. 
  • Retinal fractals and acute lacunar stroke. 
  • Retinal microvascular changes and subsequent vascular events after ischemic stroke. 
  • Retinal vascular caliber and extracranial carotid disease in patients with acute ischemic stroke: the Multi-Centre Retinal Stroke (MCRS) study. 
  • Risk adjustment of ischemic stroke outcomes for comparing hospital performance: a statement for healthcare professionals from the American Heart Association/American Stroke Association. 
  • Risk of ischemic stroke with tamoxifen treatment for breast cancer: a meta-analysis. 
  • Risk of stroke and bleeding in relation to hypertension in anticoagulated patients with atrial fibrillation: a meta-analysis of randomised controlled trials. 
  • Risks and Benefits Associated With Prestroke Antiplatelet Therapy Among Patients With Acute Ischemic Stroke Treated With Intravenous Tissue Plasminogen Activator. 
  • Risks of intracranial hemorrhage among patients with acute ischemic stroke receiving warfarin and treated with intravenous tissue plasminogen activator. 
  • Role of routine transthoracic echocardiography in evaluation and management of stroke. 
  • Role of vascular mitogens in subarachnoid hemorrhage-associated cerebral vasculopathy. 
  • SARS-CoV-2 and Stroke in a New York Healthcare System. 
  • SUMOylation in brain ischemia: Patterns, targets, and translational implications. 
  • Safety and Outcomes of Intravenous tPA in Acute Ischemic Stroke Patients With Prior Stroke Within 3 Months: Findings From Get With The Guidelines-Stroke. 
  • Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial. 
  • Safety of Computed Tomographic Angiography in the Evaluation of Patients With Acute Stroke: A Single-Center Experience. 
  • Screening with MRI for Accurate and Rapid Stroke Treatment: SMART. 
  • Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration. 
  • Secondary prevention of ischaemic stroke: more evidence to block two pathways affecting platelet activation. 
  • Secondary stroke prevention strategies for the oldest patients: possibilities and challenges. 
  • Selective gamma-aminobutyric acid type A receptor antagonism reverses isoflurane ischemic neuroprotection. 
  • Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts. 
  • Serum alpha-1 antitrypsin in acute ischemic stroke: A prospective pilot study. 
  • Serum fatty acids and incidence of ischemic stroke among postmenopausal women. 
  • Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. 
  • Severe hypotension is not essential for isoflurane neuroprotection against forebrain ischemia in mice. 
  • Sex Differences in Endovascular Therapy for Ischemic Stroke: Results From the Get With The Guidelines-Stroke Registry. 
  • Sex differences in delayed cerebral ischemia after subarachnoid hemorrhage. 
  • Should antihypertensive therapies be given to patients with acute ischemic stroke? 
  • Should lumbar puncture be part of the routine evaluation of patients with cerebral ischemia? 
  • Should lumbar puncture be part of the routine evaluation of patients with cerebral ischemia? 
  • Similar motor recovery of upper and lower extremities after stroke. 
  • Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. 
  • Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage: results of a pilot randomized clinical trial. 
  • Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice: putative protective proteins/pathways. 
  • Smoking and ischemic stroke: a role for nicotine? 
  • Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke. 
  • Statin pretreatment is associated with better outcomes in large artery atherosclerotic stroke. 
  • Statin therapy should be discontinued in patients with intracerebral hemorrhage. 
  • Statins and ischemic stroke severity: cytoprotection. 
  • Statins and the Risk of Intracerebral Hemorrhage in Patients With Previous Ischemic Stroke or Transient Ischemic Attack. 
  • Strategies used by hospitals to improve speed of tissue-type plasminogen activator treatment in acute ischemic stroke. 
  • Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies. 
  • Stroke code chest radiographs are not useful. 
  • Stroke due to recurrent ipsilateral carotid artery dissection in a young adult. 
  • Stroke in young cannabis users (18-49 years): National trends in hospitalizations and outcomes. 
  • Strokelore: Antithrombotic therapy and hemorrhagic infarction. 
  • Summary of evidence-based guideline: Periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular disease: report of the Guideline Development Subcommittee of the American Academy of Neurology. 
  • Summary of evidence-based guideline: periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular disease: report of the Guideline Development Subcommittee of the American Academy of Neurology. 
  • Superparamagnetic iron oxide labeling and transplantation of adipose-derived stem cells in middle cerebral artery occlusion-injured mice. 
  • Sympathetic ganglionic blockade masks beneficial effect of isoflurane on histologic outcome from near-complete forebrain ischemia in the rat. 
  • Symptomatic Carotid Occlusion Is Frequently Associated With Microembolization. 
  • Symptomatic autoregulatory failure in acute ischemic stroke. 
  • Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhage. 
  • Targeting the SUMO pathway for neuroprotection in brain ischaemia. 
  • Temporal changes in cerebral tissue oxygenation with cerebrovascular pressure reactivity in severe traumatic brain injury. 
  • Temporal trends and rural-urban disparities in cerebrovascular risk factors, in-hospital management and outcomes in ischaemic strokes in China from 2005 to 2015: a nationwide serial cross-sectional survey. 
  • Tenecteplase versus alteplase for management of acute ischemic stroke: a pairwise and network meta-analysis of randomized clinical trials. 
  • Testing the Presumption of Consent to Emergency Treatment for Acute Ischemic Stroke 
  • The Addition of Atrial Fibrillation to the Los Angeles Motor Scale May Improve Prediction of Large Vessel Occlusion. 
  • The Carotid Occlusion Surgery Study. 
  • The HVAD Left Ventricular Assist Device: Risk Factors for Neurological Events and Risk Mitigation Strategies. 
  • The Need for Speed. 
  • The Role of SUMOylation and Ubiquitination in Brain Ischaemia: Critical Concepts and Clinical Implications. 
  • The Stroke P.O.R.T.: secondary and tertiary prevention of ischemic stroke. Stroke Prevention Patient Outcomes Research Team. 
  • The application of permanent middle cerebral artery ligation in the mouse. 
  • The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia. 
  • The construct validity of the ischemic score of Hachinski for the detection of dementias. 
  • The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat. 
  • The epidemiology, evaluation and treatment of stroke in adults with sickle cell disease. 
  • The king is dead (warfarin): direct thrombin and factor Xa inhibitors: the next Diadochian War? 
  • The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. 
  • The quest for the "Holy Grail" of ischemic stroke cytoprotection: Statins may not be the answer. 
  • The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events. 
  • The stroke that struck back: an unusual alien hand presentation. 
  • The use of positron emission tomography in cerebrovascular disease. 
  • The vascular depression subtype: evidence of internal validity. 
  • Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage. 
  • Thromboembolic Events with Enterprise Versus Pipeline: Porcine In Vivo Experiment. 
  • Thrombolysis for acute ischemic stroke in patients with cancer: a population study. 
  • Thrombolysis in young adults with acute ischemic stroke: Quicker may be better. 
  • Thrombolysis in young adults with stroke: Findings from Get With The Guidelines-Stroke. 
  • Thrombolytic therapy of acute ischemic stroke: correlation of angiographic recanalization with clinical outcome. 
  • Thromobolysis for acute ischemic stroke: is intra-arterial better than intravenous? A treatment effects model. 
  • Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. 
  • Time since stroke and risk of adverse outcomes after surgery. 
  • Time to Endovascular Reperfusion and Outcome in Acute Ischemic Stroke : A Nationwide Prospective Registry in China. 
  • Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. 
  • Time-Varying Effects of Prasugrel Versus Clopidogrel on the Long-Term Risks of Stroke After Acute Coronary Syndromes: Results From the TRILOGY ACS Trial. 
  • Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes. 
  • Timing of symptomatic vasospasm in aneurysmal subarachnoid hemorrhage: the effect of treatment modality and clinical implications. 
  • Tirofiban Protocol Protects Against Delayed Cerebral Ischemia: A Case-Series Study. 
  • To Treat or Not to Treat: Low-Dose Alteplase for Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants Within 24 Hours. 
  • Tracking brain volume changes in C57BL/6J and ApoE-deficient mice in a model of neurodegeneration: a 5-week longitudinal micro-MRI study. 
  • Traditional risk factors and combined genetic markers of recurrent ischemic stroke in adults: Comment from Wilson et al. 
  • Transglutaminase 2 protects against ischemic stroke. 
  • Translational research in acute central nervous system injury: lessons learned and the future. 
  • Treatment of atrial fibrillation in East Asia: what is perception and what is reality? 
  • Treatment with tissue plasminogen activator and inpatient mortality rates for patients with ischemic stroke treated in community hospitals. 
  • Treatments-Preventive. 
  • Trends in endovascular therapy and clinical outcomes within the nationwide Get With The Guidelines-Stroke registry. 
  • Troponin Improves the Yield of Transthoracic Echocardiography in Ischemic Stroke Patients of Determined Stroke Subtype. 
  • US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Carotid endarterectomy. 
  • US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Medical therapy in patients with carotid artery stenosis. 
  • US national survey of physician practices for the secondary and tertiary prevention of ischemic stroke. Design, service availability, and common practices. 
  • Unexplained Variation for Hospitals' Use of Inpatient Rehabilitation and Skilled Nursing Facilities After an Acute Ischemic Stroke. 
  • Unfolded protein response in brain ischemia: A timely update. 
  • Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. 
  • Use and Outcomes of Intravenous Thrombolysis for Acute Ischemic Stroke in Patients ≥90 Years of Age. 
  • Use of Strategies to Improve Door-to-Needle Times With Tissue-Type Plasminogen Activator in Acute Ischemic Stroke in Clinical Practice: Findings from Target: Stroke. 
  • Use of a Smartphone Platform to Help With Emergency Management of Acute Ischemic Stroke: Observational Study. 
  • Use of a vascular reconstruction device to salvage acute ischemic occlusions refractory to traditional endovascular recanalization methods. 
  • Use of antithrombotic medications among elderly ischemic stroke patients. 
  • Use of barbiturate therapy in severe perinatal asphyxia: a randomized controlled trial. 
  • Use of emergency department transcranial Doppler assessment of reperfusion after intravenous tPA for ischemic stroke. 
  • Use of specialized coagulation testing in the evaluation of patients with acute ischemic stroke. 
  • Use, Temporal Trends, and Outcomes of Endovascular Therapy After Interhospital Transfer in the United States. 
  • Utilization of intravenous tissue plasminogen activator for ischemic stroke: are there sex differences? 
  • Value of preoperative EEG for carotid endarterectomy. 
  • Venous thromboembolism in the Get With The Guidelines-Stroke acute ischemic stroke population: incidence and patterns of prophylaxis. 
  • Very Early Constraint-Induced Movement during Stroke Rehabilitation (VECTORS): A single-center RCT. 
  • Veterans Administration Acute Stroke (VASt) Study: lack of race/ethnic-based differences in utilization of stroke-related procedures or services. 
  • Visual complications after stent-assisted endovascular embolization of paraophthalmic and suprasellar variant superior hypophyseal aneurysms: the Duke Cerebrovascular Center experience in 57 patients. 
  • Vorapaxar in the secondary prevention of atherothrombotic events. 
  • Warfarin or aspirin for recurrent ischemic stroke. 
  • Warming during cardiopulmonary bypass is associated with jugular bulb desaturation. 
  • Wegener granulomatosis: CT and MR findings. 
  • When Low-Risk Atrial Fibrillation Is Not So Low Risk: Beast of Burden. 
  • XBP1 (X-Box-Binding Protein-1)-Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G. 
  • [Bcl-2 and bax expression in rat cerebral ischemic preconditioning]. 
  • gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia. 
  • pH-stat cooling improves cerebral metabolic recovery after circulatory arrest in a piglet model of aortopulmonary collaterals. 
  • β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. 
• 

  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Reed, Shelby Derene, Professor in Population Health Sciences, Duke Science & Society
  • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society
  • Shah, Shreyansh, Assistant Professor of Neurology, Neurology, Neurocritical Care
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology