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Subject Areas on Research
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3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility.
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31P NMR probes of chemical dynamics: paramagnetic relaxation enhancement of the (1)H and (31)P NMR resonances of methyl phosphite and methylethyl phosphate anions by selected metal complexes.
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A combined explicit-implicit method for high accuracy reaction path integration.
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A protein corona primer for physical chemists.
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A simple method for fabricating artificial kidney stones of different physical properties.
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A spatially explicit investigation of phosphorus sorption and related soil properties in two riparian wetlands.
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AN OPTICAL ROTATORY DISPERSION STUDY OF ASPARTIC AMINO TRANSFERASE.
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Adapting the nudged elastic band method for determining minimum-energy paths of chemical reactions in enzymes.
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Altered ultrastructural morphology of self-aggregated low density lipoproteins: coalescence of lipid domains forming droplets and vesicles.
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Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes.
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Amiodarone-liposome interaction: a multinuclear NMR and X-ray diffraction study.
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An empirical model for electrostatic interactions in proteins incorporating multiple geometry-dependent dielectric constants.
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Antitumor Agents. 154. Cytotoxic and Antimitotic Flavonols from Polanisia dodecandra
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Application of the temperature-jump technique to the study of phospholipid dispersions.
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Architecture of Limulus polyphemus hemocyanin.
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B-DNA to zip-DNA: simulating a DNA transition to a novel structure with enhanced charge-transport characteristics.
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Binding of phosphate ligands to ribonuclease A.
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Biomembrane templates for nanoscale conduits and networks.
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Brain adducin: a protein kinase C substrate that may mediate site-directed assembly at the spectrin-actin junction.
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Calcium measurements with electron probe X-ray and electron energy loss analysis.
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Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine.
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Clinical and biochemical presentation of gouty diathesis: comparison of uric acid versus pure calcium stone formation.
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Contributions of hydration and steric (entropic) pressures to the interactions between phosphatidylcholine bilayers: experiments with the subgel phase.
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Coupling coherence distinguishes structure sensitivity in protein electron transfer.
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Cytochrome oxidase: structural insights from electron microscopy and from secondary structure prediction.
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Desmoplakin I and desmoplakin II. Purification and characterization.
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Detection thresholds of potassium salts are related to the molar conductivity of the anion.
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Drug targeting using thermally responsive polymers and local hyperthermia.
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EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme.
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Effect of conformation on the binding of flavins to flavoenzymes.
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Effect of erionite on the pleural mesothelium of the Fischer 344 rat.
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Electron microscopy of fibrinogen, its plasmic fragments and small polymers.
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Equilibrium and nonequilibrium phase transformations of quaternary solutions based on a physiologic support medium containing NaCl, dimethyl sulfoxide, and glycerol.
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Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.
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Evidence that Blastocladiella emersonii zoospore maintenance factor is a sulfhydryl group-containing cyclic ribotide.
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Existence of a flat phase in red cell membrane skeletons.
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Exposure to concentrated ambient particles (CAPs): a review.
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Fe(III) coordination properties of a new saccharide-based exocyclic trihydroxamate analogue of ferrichrome.
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Fe(III) coordination properties of two new saccharide-based enterobactin analogues: methyl 2,3,4-tris-O-[N-[2,3-di(hydroxy)benzoyl-glycyl]-aminopropyl]-alpha-D-glucopyranoside and methyl 2,3,4-tris-O-[N-[2,3-di-(hydroxy)-benzoyl]-aminopropyl]-alpha-D-glucopyranoside.
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Femtosecond phase-coherent two-dimensional spectroscopy.
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Founder's Award, Society for Biomaterials. Sixth World Biomaterials Congress 2000, Kamuela, HI,May 15-20, 2000. Really smart bioconjugates of smart polymers and receptor proteins.
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Hemoglobins from trout: structural and functional properties.
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High-resolution, >1 GHz NMR in unstable magnetic fields.
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Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ.
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Hydration and steric pressures between phospholipid bilayers.
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Identification of a glutathione S-transferase without affinity for glutathione sepharose in human kidney.
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Identification of quantitative trait loci influencing wood specific gravity in an outbred pedigree of loblolly pine.
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Induction of selective biological responses to chemoattractants in a human monocyte-like cell line.
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Influence of denaturing agents on solvent structure.
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Integrated single-walled carbon nanotube/microfluidic devices for the study of the sensing mechanism of nanotube sensors.
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Interaction of benzene with bilayers. Thermal and structural studies.
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Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine.
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Isolation and characterization of a protein from rat testis which inhibits cyclic AMP-dependent protein kinase and phosdiesterase.
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Isolation and characterization of a receptor for type 1 fimbriae of Escherichia coli from guinea pig erythrocytes.
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Isolation of an ankyrin-band 3 oligomer from human erythrocyte membranes.
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Joint modeling of DNA sequence and physical properties to improve eukaryotic promoter recognition.
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Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.
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MINORITY CARRIER TRAPPING AND DYE SENSITIZATION.
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Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.
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Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx.
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Molecular and regulatory properties of adrenergic receptors.
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Monte Carlo simulation and molecular theory of tethered polyelectrolytes.
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Nuclear quantum effects on an enzyme-catalyzed reaction with reaction path potential: proton transfer in triosephosphate isomerase.
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Optical rotatory dispersion of ribonuclease and ribonuclease--nucleotide complexes.
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Optimization of the lariat ether carboxylic acid host structure for ferrioxamine B: demonstration of a second coordination shell chelate effect.
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Oxygen dissociation curve of echidna blood.
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Photoelectric phenomena in hemoglobin and dyed gelatin.
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Physical and chemical properties of rabbit muscle phosphofructokinase cross-linked with dimethyl suberimidate.
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Physical organic chemistry of supramolecular polymers.
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Physicochemical characteristics and biological effects of nickel oxides.
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Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines.
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Profound increase in viscosity and aggregation of pig gastric mucin at low pH.
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Protein design and folding: template trapping of self-assembled helical bundles.
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Protein electron transfer rates set by the bridging secondary and tertiary structure.
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Protein-resistant polymer coatings on silicon oxide by surface-initiated atom transfer radical polymerization.
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Quadratic string method for determining the minimum-energy path based on multiobjective optimization.
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Quantitative structure-activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase.
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Quantum mechanics/molecular mechanics minimum free-energy path for accurate reaction energetics in solution and enzymes: sequential sampling and optimization on the potential of mean force surface.
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Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.
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Regulatory domains of erythrocyte ankyrin.
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Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate.
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Relaxation spectra of enzymatic reactions.
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STRUCTURE OF STREPTOLYDIGIN.
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Sculpting proteins interactively: continual energy minimization embedded in a graphical modeling system.
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Simulation of electron transfer between cytochrome C2 and the bacterial photosynthetic reaction center: Brownian dynamics analysis of the native proteins and double mutants.
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Structural mapping of chloroplast coupling factor.
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Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors.
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Structure-activity relationships of noreperidine congeners on cholinesterase systems in vitro and analgesia in vivo.
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Studies of the ethanol-induced interdigitated gel phase in phosphatidylcholines using the fluorophore 1,6-diphenyl-1,3,5-hexatriene.
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Surface ripples cause the large fluid spaces between gel phase bilayers containing small amounts of cholesterol.
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Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing.
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Synthetic and model computational studies of molar rotation additivity for interacting chiral centers: a reinvestigation of van't Hoff's principle.
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The Alacoil: a very tight, antiparallel coiled-coil of helices.
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The H2O-NaCl-glycerol phase diagram and its application in cryobiology.
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The crystal structure of bovine Cu2+,Zn2+ superoxide dismutase at 5.5-A resolution.
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The crystal structure of the collagen-like polypeptide (glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)9 at 1.55 A resolution shows up-puckering of the proline ring in the Xaa position.
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The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.
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The heme and Fe4S4 cluster in the crystallographic structure of Escherichia coli sulfite reductase.
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The human thymic microenvironment: cortical thymic epithelium is an antigenically distinct region of the thymic microenvironment.
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The interaction of aspartate aminotransferase with alpha-methylaspartic acid.
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The nature of aqueous tunneling pathways between electron-transfer proteins.
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The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase.
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Towards Raman optical activity calculations of large molecules.
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Transdermal drug delivery enhanced and controlled by erbium:YAG laser: a comparative study of lipophilic and hydrophilic drugs.
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ULTRASONIC ATTENUATION MEASUREMENTS IN POLY-L-GLUAMIC ACID SOLUTIONS.
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Ultrasonic absorption measurements in aqueous solutions of glycine, diglycine, and triglycine.
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Ultrasonic attenuation measurements in phospholipid dispersions.
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Velocity effects on fullerene and oxide nanoparticle deposition in porous media.
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Walter Kauzmann: an undergraduate perspective.
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Keywords of People
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Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
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Beratan, David N.,
R.J. Reynolds Distinguished Professor of Chemistry,
Nicholas Institute-Energy Initiative
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Cianciolo, George James,
Associate Professor Emeritus of Pathology,
Pathology
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Craig, Stephen L,
William T. Miller Distinguished Professor of Chemistry,
Nicholas Institute-Energy Initiative
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Erickson, Harold Paul,
James B. Duke Distinguished Professor of Cell Biology,
Cell Biology
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Preminger, Glenn Michael,
James F. Glenn, M.D. Distinguished Professor of Urology,
Surgery, Urology