Chemotactic Factors
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Subject Areas on Research
- A blood-based biomarker panel to detect acute stroke.
- A guanine nucleotide regulatory protein controls polyphosphoinositide metabolism, Ca2+ mobilization, and cellular responses to chemoattractants in human monocytes.
- A simulation environment for directional sensing as a phase separation process.
- Absence of macrophage involvement in the passive serum therapy of Friend leukemia virus-induced disease.
- Acetyl-CoA:1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase is directly activated by p38 kinase.
- Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.
- Acute ethanol administration downregulates human immunodeficiency virus-1 glycoprotein 120-induced KC and RANTES production by murine Kupffer cells and splenocytes.
- Alterations of new methylated phospholipid synthesis in the plasma membranes of macrophages exposed to chemoattractants.
- Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats.
- Antiinflammatory proteins associated with human and murine neoplasms.
- Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines.
- Blastomyces dermatitidis chemotactic factor: kinetics of production and biological characterization evaluated by a modified neutrophil chemotaxis assay.
- Capillary zone electrophoresis-mass spectrometry using a coaxial continuous-flow fast atom bombardment interface.
- Changes in macrophages and their functions with aging in C57BL/6J, AKR/J, and SJL/J mice.
- Changing concepts in pathophysiology of the vasculitides.
- Characteristics of the chemotactic activity of heparin cofactor II proteolysis products.
- Chemoattractant receptors on phagocytic cells.
- Chemotactic activity of cerebrospinal fluid in experimental cryptococcal meningitis.
- Chemotactic factor and P15E-related chemotaxis inhibitor in human melanoma cell lines with different macrophage content and tumorigenicity in nude mice.
- Chemotactically responsive and nonresposive forms of a continuous human monocyte cell line.
- Chemotaxis by a CNS macrophage, the microglia.
- Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination.
- Coexistence of a chemotactic factor and a retroviral P15E-related chemotaxis inhibitor in human tumor cell culture supernatants.
- Corneal organ cultures in tyrosinemia release chemotactic factors.
- Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
- Demonstration of a chemotactic factor receptor on macrophages.
- Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry.
- Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.
- Development of specific receptors for N-formylated chemotactic peptides in a human monocyte cell line stimulated with lymphokines.
- Different G(i)-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils.
- Disorders of human leukocyte chemotaxis.
- Effect of membrane fluidizers on the number and affinity of chemotactic factor receptors on human polymorphonuclear leukocytes.
- Effects of culture filtrates of Blastomyces dermatitidis on neutrophil locomotion.
- Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
- Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells.
- Fluorine-18 labeled chemotactic peptides: a potential approach for the PET imaging of bacterial infection.
- Further studies of a macrophage chemotaxis inhibitor (MCI) produced by neoplasms: murine tumors free of lactic dehydrogenase virus produce MCI.
- GABA-induced chemokinesis and NGF-induced chemotaxis of embryonic spinal cord neurons.
- Generation of a fibroblast chemotactic factor in serum by activation of complement.
- Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.
- Induction of selective biological responses to chemoattractants in a human monocyte-like cell line.
- Inhaled asbestos activates a complement-dependent chemoattractant for macrophages.
- Inhibition of 125I-chemotactic peptide uptake by protease inhibitors.
- Inhibitors of monocyte responses to chemotaxins are associated with human neoplasms.
- L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits.
- Leukocyte chemoattractant peptides from the serpin heparin cofactor II.
- MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.
- Male-specific cell migration into the developing gonad.
- Malignant melanoma induces migration and invasion of adult mesenchymal stem cells.
- Mechanisms of inflammation and leukocyte activation.
- Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases.
- Model for leukocyte regulation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism.
- Molecular and cellular mechanisms of leukocyte chemotaxis.
- Molecular mechanisms of leukocyte activation by chemoattractants.
- Monocyte chemotactic peptide receptor. Functional characteristics and ligand-induced regulation.
- Monocyte responsiveness to chemotactic stimuli is a property of a subpopulation of cells that can respond to multiple chemoattractants.
- Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth.
- Pharmacologic manipulation of leukocyte chemotaxis. Present knowledge and future trends.
- Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines.
- Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2.
- Regulation of inositol phospholipid and inositol phosphate metabolism in chemoattractant-activated human polymorphonuclear leukocytes.
- Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants.
- Role of guanine nucleotide regulatory protein in polyphosphoinositide degradation and activation of phagocytic leukocytes by chemoattractants.
- SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.
- Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines.
- Signal transduction in cells following binding of chemoattractants to membrane receptors.
- Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
- Suppression of tumor formation in vivo by expression of the JE gene in malignant cells.
- The DEK nuclear autoantigen is a secreted chemotactic factor.
- The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations.
- The effects of heparin cofactor II-derived chemotaxins on neutrophil actin conformation and cyclic AMP levels.
- The human cytokine I-309 is a monocyte chemoattractant.
- The robustness of the transcriptional response to alterations in morphogenetic gradients.
- Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
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Keywords of People
- Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
- Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
- Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society