-
Subject Areas on Research
-
2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation.
-
A cell-intrinsic role for Mst1 in regulating thymocyte egress.
-
A chemotactic factor for mononuclear leukocytes.
-
A human mononuclear leukocyte chemotactic factor: characterization, specificity and kinetics of production by homologous leukocytes.
-
A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin.
-
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1.
-
A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis.
-
A simulation environment for directional sensing as a phase separation process.
-
Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome.
-
Abnormalities of leukocyte chemotaxis in human disease.
-
Activation of pp60c-src is necessary for human vascular smooth muscle cell migration.
-
Age-dependent alterations of peritoneal exudate macrophages in autoimmune-prone and autoimmune-resistant mouse strains.
-
An inhibitor of macrophage chemotaxis produced by neoplasms.
-
Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.
-
Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity.
-
Augmentation of human monocyte chemotactic response by levamisole.
-
Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.
-
Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis.
-
Beta-arrestin-2 regulates the development of allergic asthma.
-
Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation.
-
Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor.
-
Biochemical characterization of Leishmania major aquaglyceroporin LmAQP1: possible role in volume regulation and osmotaxis.
-
Biologic and biochemical activities of continuous macrophage cell lines P388D1 and J774.1.
-
Biological activity of complement in vivo. Role of C5 in the accumulation of polymorphonuclear leukocytes in inflammatory exudates.
-
Calcium influx requirement for human neutrophil chemotaxis: inhibition by lanthanum chloride.
-
Characterization of chemotactic activity produced in vivo by a cell-mediated immune reaction in the guinea pig.
-
Characterization of multiple CD34+ cell populations in cord blood.
-
Chemical waves in cell and developmental biology.
-
Chemoattractant receptor cross-desensitization.
-
Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage.
-
Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement.
-
Chemotactic movement of a polarity site enables yeast cells to find their mates.
-
Chemotaxis by a CNS macrophage, the microglia.
-
Chemotaxis of inflammatory cells.
-
Chemotaxis of mononuclear leukocytes.
-
Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform.
-
Chemotropism and Cell-Cell Fusion in Fungi.
-
Comparative Antennal and Behavioral Responses of Summer and Winter Morph Drosophila suzukii (Diptera: Drosophilidae) to Ecologically Relevant Volatiles.
-
Complement-mediated vasoconstriction and graft rejection.
-
Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.
-
Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion.
-
Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration.
-
Crystal structure of activated CheY. Comparison with other activated receiver domains.
-
Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling.
-
Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase.
-
Cytogenetic engineering in vivo: restoration of biologic complement activity to C5-deficient mice by intravenous inoculation of hybrid cells.
-
Defective monocyte function in patients with genitourinary carcinoma.
-
Defective mononuclear leukocyte chemotaxis: a previously unrecognized immune dysfunction. Studies in a patient with chronic mucocutaneous candidiasis.
-
Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.
-
Depressed monocyte chemotaxis during acute influenza infection.
-
Depression of human monocyte chemotaxis by herpes simplex and influenza viruses.
-
Depression of macrophage function by a factor produced by neoplasms: a merchanism for abrogation of immune surveillance.
-
Diffusion-limited phase separation in eukaryotic chemotaxis.
-
Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux.
-
Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity.
-
Effect of C4 depletion on the utilization of the terminal components of guinea-pig complement by endotoxin.
-
Effect of virus infection on the inflammatory response. Depression of macrophage accumulation in influenza-infected mice.
-
Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.
-
Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice.
-
Enhancing Schwann cell migration using concentration gradients of laminin-derived peptides.
-
Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction.
-
Evaluation of a cytocentrifuge method for measuring neutrophil granulocyte chemotaxis.
-
Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells.
-
Factors from saliva and oral bacteria, chemotactic for polymorphonuclear leukocytes: their possible role in gingival inflammation.
-
Familial deficiency of the seventh component of complement associated with recurrent bacteremic infections due to Neisseria.
-
Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region.
-
Function of microglia in organotypic slice cultures.
-
Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans.
-
Generation of a fibroblast chemotactic factor in serum by activation of complement.
-
Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C42 sites.
-
Genetic Screen Reveals Link between the Maternal Effect Sterile Gene mes-1 and Pseudomonas aeruginosa-induced Neurodegeneration in Caenorhabditis elegans.
-
Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses.
-
Glutamate acting at NMDA receptors stimulates embryonic cortical neuronal migration.
-
HDAC6 is a microtubule-associated deacetylase.
-
HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response.
-
Haptotactic gradients for directed cell migration: stimulation and inhibition using soluble factors.
-
Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors.
-
Human platelets exhibit chemotaxis using functional N-formyl peptide receptors.
-
Humoral mediators of chemotaxis of mononuclear leukocytes.
-
Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction.
-
Immune-inflammation gene signatures in endometriosis patients.
-
Immunological mechanisms of periodontal tissue destruction.
-
Induction of selective biological responses to chemoattractants in a human monocyte-like cell line.
-
Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells.
-
Inflammation and viral infection: chemotactic activity resulting from the interaction of antiviral antibody and complement with cells infected with herpes simplex virus.
-
Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis.
-
Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes.
-
LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
-
LRRK2 inhibition attenuates microglial inflammatory responses.
-
Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response.
-
Leukocyte chemotactic activity from oral bacteria.
-
Lipid requirements for leukocyte chemotaxis and phagocytosis: effects of inhibitors of phospholipid and cholesterol synthesis.
-
Macrophage proteinase and inflammation: the production of chemotactic activity from the fifth complement by macrophage proteinase.
-
Malignant melanoma induces migration and invasion of adult mesenchymal stem cells.
-
Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration.
-
Mechanical stress and nitric oxide influence leukotriene production in cartilage.
-
Mechanisms of excitation and adaptation in Dictyostelium.
-
Mediators of the chemotaxis of mononuclear leucocytes.
-
Monocyte chemoattractant activity of Ser195-->Ala active site mutant recombinant alpha-thrombin.
-
Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion.
-
N-Formylmethionyl peptide receptors on equine leukocytes initiate secretion but not chemotaxis.
-
NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.
-
Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization.
-
Osteoprotegerin in bone metastases: mathematical solution to the puzzle.
-
Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells reduces neointimal hyperplasia.
-
PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.
-
Phospholipid methylation in macrophages is inhibited by chemotactic factors.
-
Potential treatment for clubfeet based on growth factor blockade.
-
Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines.
-
Production of chemotactic activity by guinea pig immunoglobulins following activation of the C3 complement shunt pathway.
-
Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus.
-
Production of chemotactic peptides by neutrophil degradation of heparin cofactor II.
-
Prostaglandins and inflammation: enhancement of monocyte chemotactic responsiveness by prostaglandin E2.
-
Quantification of mouse macrophage chemotaxis in vitro: role of C5 for the production of chemotactic activity.
-
Random Search in Fluid Flow Aided by Chemotaxis.
-
Rapid chemotactic response enables marine bacteria to exploit ephemeral microscale nutrient patches.
-
Reaction of a cobra venom factor with guinea pig complement and generation of an activity chemotactic for polymorphonuclear leukocytes.
-
Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury.
-
Redox regulation of neuronal migration in a Down Syndrome model.
-
Regulation of microglial function by interferons.
-
Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production.
-
Resistance of neoplasms to immunological destruction: role of a macrophage chemotaxis inhibitor.
-
Role of Polarized G Protein Signaling in Tracking Pheromone Gradients.
-
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility.
-
Seven-transmembrane receptor signaling through beta-arrestin.
-
Should we B-leavin' now?
-
Significance of complement to the mechanism of action of endotoxin.
-
Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase.
-
Statins and nitric oxide donors affect thrombospondin 1-induced chemotaxis.
-
Stepping between membrane microdomains.
-
Stimulation of neutrophil oxidative metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate.
-
T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis.
-
The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
-
The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
-
The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2.
-
The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor.
-
The effects of nicotine on vascular smooth muscle cell chemotaxis induced by thrombospondin-1 and fibronectin.
-
The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner.
-
The regulation of primary mesenchyme cell migration in the sea urchin embryo: transplantations of cells and latex beads.
-
The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases.
-
The role of integrins in saphenous vein vascular smooth muscle cell migration.
-
The role of the immune response in the development of periodontal disease.
-
Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability.
-
Tracking shallow chemical gradients by actin-driven wandering of the polarization site.
-
Transduction of receptor signals by beta-arrestins.
-
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
-
Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated.
-
beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation.
-
β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.
-
Keywords of People
-
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
-
Gunn, Michael Dee,
Professor of Medicine,
Immunology
-
Lew, Daniel Julio,
James B. Duke Distinguished Professor of Pharmacology and Cancer Biology,
Cell Biology
-
Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Shinohara, Mari L.,
Associate Professor of Immunology,
Cell Biology
-
Tsalik, Ephraim,
Adjunct Associate Professor in the Department of Medicine,
Medicine, Infectious Diseases