Chest Pain

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  Subject Areas on Research

  • 2015 ACR/ACC/AHA/AATS/ACEP/ASNC/NASCI/SAEM/SCCT/SCMR/SCPC/SNMMI/STR/STS Appropriate Utilization of Cardiovascular Imaging in Emergency Department Patients With Chest Pain: A Joint Document of the American College of Radiology Appropriateness Criteria Committee and the American College of Cardiology Appropriate Use Criteria Task Force. 
  • 2015 ACR/ACC/AHA/AATS/ACEP/ASNC/NASCI/SAEM/SCCT/SCMR/SCPC/SNMMI/STR/STS Appropriate Utilization of Cardiovascular Imaging in Emergency Department Patients With Chest Pain: A Joint Document of the American College of Radiology Appropriateness Criteria Committee and the American College of Cardiology Appropriate Use Criteria Task Force. 
  • A 28-year-old man with chest and joint pains. 
  • A 37-Year-Old Man With Pleuritic Chest Pain. 
  • A 37-year-old man with chest pain, ECG changes, and elevated cardiac enzymes. 
  • A Brief Interview to Detect Panic Attacks and Panic Disorder in Emergency Department Patients with Cardiopulmonary Complaints. 
  • A Tale of 2 Tests. 
  • A comparison of the costs of and quality of life after coronary angioplasty or coronary surgery for multivessel coronary artery disease. Results from the Emory Angioplasty Versus Surgery Trial (EAST). 
  • A meta-analysis and systematic review of computed tomography angiography as a diagnostic triage tool for patients with chest pain presenting to the emergency department. 
  • A randomized controlled trial of paroxetine for noncardiac chest pain. 
  • ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines). 
  • ACCF/ASE/ACEP/AHA/ASNC/SCAI/SCCT/SCMR 2008 appropriateness criteria for stress echocardiography: a report of the American College of Cardiology Foundation Appropriateness Criteria Task Force, American Society of Echocardiography, American College of Emergency Physicians, American Heart Association, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance: endorsed by the Heart Rhythm Society and the Society of Critical Care Medicine. 
  • ACI-TIPI clinical trial. Acute cardiac ischemia time-insensitive predictive instrument. 
  • ACR Appropriateness Criteria® Acute Chest Pain-Suspected Pulmonary Embolism. 
  • ACR Appropriateness Criteria® Chronic Chest Pain-Noncardiac Etiology Unlikely-Low to Intermediate Probability of Coronary Artery Disease. 
  • ACR Appropriateness Criteria® Nontraumatic Chest Wall Pain. 
  • Adverse reaction characterized by chest pain, shortness of breath, and syncope associated with verteporfin (visudyne). 
  • Age-Related Differences in the Noninvasive Evaluation for Possible Coronary Artery Disease: Insights From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Trial. 
  • An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial. 
  • Application of the Pediatric Appropriate Use Criteria for Chest Pain. 
  • Assessment of the myocardium on 2-phase cardiac multidetector computed tomography: does cyclic cardiac contraction influence myocardial attenuation? 
  • Association of Metabolic Phenotypes With Coronary Artery Disease and Cardiovascular Events in Patients With Stable Chest Pain. 
  • Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. 
  • Bedside multimarker testing for risk stratification in chest pain units: The chest pain evaluation by creatine kinase-MB, myoglobin, and troponin I (CHECKMATE) study. 
  • Boy With Fever and Cough. 
  • Can electrocardiographic criteria predict adverse cardiac events and positive cardiac markers? 
  • Cardiac Magnetic Resonance Stress Perfusion Imaging for Evaluation of Patients With Chest Pain. 
  • Cardiac marker testing: where should we focus? 
  • Cardiac troponin T and cardiac troponin I: relative values in short-term risk stratification of patients with acute coronary syndromes. GUSTO-IIa Investigators. 
  • Cardiovascular Testing and Clinical Outcomes in Emergency Department Patients With Chest Pain. 
  • Care of the Patient with Chest Pain in the Observation Unit. 
  • Characteristics of lung cancer in elderly patients. 
  • Chest Pain Redux: Updated and Patient Centered. 
  • Chest Pain: If It Is Not the Heart, What Is It? 
  • Chest discomfort associated with liposomal amphotericin B: report of three cases and review of the literature. 
  • Chest pain associated with moderator band pacing. 
  • Chest pain in the absence of coronary artery disease: a biopsychosocial perspective. 
  • Chest pain in the adolescent and young adult. 
  • Chest pain presenting as ischemic heart disease. Congenital absence of the pericardium. 
  • Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy. 
  • Clinical Effectiveness of Cardiac Noninvasive Diagnostic Testing in Patients Discharged From the Emergency Department for Chest Pain. 
  • Cocaine-associated chest pain: a case of aortic dissection. 
  • Combination of Goldman risk and initial cardiac troponin I for emergency department chest pain patient risk stratification. 
  • Comparison of 30-day outcome, resource use, and coronary artery disease severity in patients with suspected coronary artery disease with and without diabetes mellitus assigned to chest pain units. 
  • Comparison of cardiac troponin T versus creatine kinase-MB for risk stratification in a chest pain evaluation unit. 
  • Comparison of the five-electrode-derived EASI electrocardiogram to the Mason Likar electrocardiogram in the prehospital setting. 
  • Consensus statement: cardiovascular safety profile of triptans (5-HT agonists) in the acute treatment of migraine. 
  • Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction). 
  • Copeptin to rule out myocardial infarction in Blacks versus Caucasians. 
  • Coronary Atherosclerosis, Cardiac Troponin, and Interleukin-6 in Patients With Chest Pain: The PROMISE Trial Results. 
  • Coronary CT Angiography as a Diagnostic and Prognostic Tool: Perspective from a Multicenter Randomized Controlled Trial: PROMISE. 
  • Coronary computed tomographic angiography and risk of all-cause mortality and nonfatal myocardial infarction in subjects without chest pain syndrome from the CONFIRM Registry (coronary CT angiography evaluation for clinical outcomes: an international multicenter registry). 
  • Cost savings in migraine associated with less chest pain on new triptan therapy. 
  • Cost-Effectiveness Analysis of Stress Cardiovascular Magnetic Resonance Imaging for Stable Chest Pain Syndromes. 
  • Cost-effectiveness Analysis of Anatomic vs Functional Index Testing in Patients With Low-Risk Stable Chest Pain. 
  • Cost-effectiveness of diagnostic strategies for patients with chest pain. 
  • Cost-effectiveness of follow-up of pulmonary nodules incidentally detected on cardiac computed tomographic angiography in patients with suspected coronary artery disease. 
  • Critical pathways for patients with acute chest pain at low risk. 
  • Current Evidence in Cardiothoracic Imaging: Computed Tomography-derived Fractional Flow Reserve in Stable Chest Pain. 
  • Deep convolutional neural networks to predict cardiovascular risk from computed tomography. 
  • Development and validation of a prioritization rule for obtaining an immediate 12-lead electrocardiogram in the emergency department to identify ST-elevation myocardial infarction. 
  • Diagnosis of pulmonary embolism. 
  • Diagnostic Strategies for the Evaluation of Chest Pain: Clinical Implications From SCOT-HEART and PROMISE. 
  • Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. 
  • Differences between chest pain observation service patients and admitted "rule-out myocardial infarction" patients. 
  • Differences in Cardiovascular Risk, Coronary Artery Disease, and Cardiac Events Between Black and White Individuals Enrolled in the PROMISE Trial. 
  • Differences in care-seeking behavior for acute chest pain in the United States and Japan. 
  • Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. 
  • Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B. 
  • Discordances between predicted and actual risk in obese patients with suspected cardiac ischaemia. 
  • Does This Child Have Pneumonia?: The Rational Clinical Examination Systematic Review. 
  • Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review. 
  • Does this patient have pulmonary embolism? 
  • Door-to-ECG time in patients with chest pain presenting to the ED. 
  • Downstream procedures and outcomes after stress testing for chest pain without known coronary artery disease in the United States. 
  • Early glycoprotein IIb/IIIa inhibitor use for non-ST-segment elevation acute coronary syndrome: patient selection and associated treatment patterns. 
  • Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease. 
  • Effect of a Triage-Based Screening Protocol on Diagnosis and Treatment of Acute Coronary Syndrome in a Tanzanian Emergency Department: A Prospective Pre-Post Study. 
  • Effects of coping skills training and sertraline in patients with non-cardiac chest pain: a randomized controlled study. 
  • Effects of iopamidol-370 versus iodixanol-320 on coronary contrast, branch depiction, and heart rate variability in dual-source coronary MDCT angiography. 
  • Eligibility for Noninvasive Testing Based on the 2021 American Heart Association/American College of Cardiology Guideline for the Evaluation and Diagnosis of Stable Chest Pain: Implications From the PROMISE Trial. 
  • Emergency department evaluation of chest pain among adult congenital heart disease patients. 
  • Emergency physician high pretest probability for acute coronary syndrome correlates with adverse cardiovascular outcomes. 
  • Endotracheal flumazenil: a new route of administration for benzodiazepine antagonism. 
  • Epicardial Adipose Tissue in Patients With Stable Chest Pain: Insights From the PROMISE Trial. 
  • Errors in Programming and Coding Affecting Cohorts Included in the Study Deriving and Validating the PROMISE Minimal-Risk Tool. 
  • Etiology of uncompleted exercise stress testing after ED chest pain evaluation. 
  • Evaluating Appropriate Use of Pediatric Echocardiograms for Chest Pain in Outpatient Clinics. 
  • Evaluating disparities in door-to-EKG time for patients with noncardiac chest pain. 
  • Failure of thrombin generation markers to triage patients presenting with chest pain. 
  • Functional vs Anatomical Testing for Patients With Stable Chest Pain-Binary or Directional Thinking? 
  • Grade 3 ischemia on admission electrocardiogram and chest pain duration predict failure of ST-segment resolution after primary percutaneous coronary intervention for acute myocardial infarction. 
  • Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department. 
  • HEART Failure? Episodes of Missed Major Cardiac Events When Applying the HEART Pathway to an Observation Unit Population. 
  • Hand-held echocardiographic examination of patients with symptoms of acute coronary syndromes in the emergency department: the 30-day outcome associated with normal left ventricular wall motion. 
  • Heart failure care and outcomes in a Tanzanian emergency department: A prospective observational study. 
  • High prevalence of lack of knowledge of symptoms of acute myocardial infarction in Pakistan and its contribution to delayed presentation to the hospital. 
  • How much do we gain by reducing time to reperfusion therapy? 
  • Hypercalcemia-induced ST-segment elevation mimicking acute myocardial infarction. 
  • Identification of Patients With Stable Chest Pain Deriving Minimal Value From Noninvasive Testing: The PROMISE Minimal-Risk Tool, A Secondary Analysis of a Randomized Clinical Trial. 
  • Identification of chest pain patients appropriate for an emergency department observation unit. 
  • Identification of patients with stable chest pain deriving minimal value from coronary computed tomography angiography: An external validation of the PROMISE minimal-risk tool. 
  • Identifying Low-risk Patients for Early Discharge From Emergency Department Without Using Subjective Descriptions of Chest Pain: Insights From Providing Rapid Out of Hospital Acute Cardiovascular Treatment (PROACT) 3 and 4 Trials. 
  • Impact of High-Deductible Health Plans on Emergency Department Patients With Nonspecific Chest Pain and Their Subsequent Care. 
  • Impact on the care of the emergency department chest pain patient from the chest pain evaluation registry (CHEPER) study. 
  • Implementation of High-Sensitivity Cardiac Troponin Assays in the United States. 
  • In patients with chest pain, HEART Pathway-guided and usual care did not differ for MACE or health care use. 
  • Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy. 
  • Integrating multimodal information in machine learning for classifying acute myocardial infarction. 
  • Is the initial diagnostic impression of "noncardiac chest pain" adequate to exclude cardiac disease? 
  • Knowledge of myocardial infarction symptoms and perceptions of self-risk in Tanzania. 
  • Learning to suspect the unexpected: evaluating women with cardiac syndromes. 
  • Left arm pain isn't always angina. 
  • Lipoprotein Subclasses Associated With High-Risk Coronary Atherosclerotic Plaque: Insights From the PROMISE Clinical Trial. 
  • Low-risk acute heart failure patients: external validation of the Society of Chest Pain Center's recommendations. 
  • Lymphangioleiomyomatosis. 
  • Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. 
  • Midregional proadrenomedullin predicts mortality and major adverse cardiac events in patients presenting with chest pain: results from the CHOPIN trial. 
  • Morbidity of DSM-IV Axis I disorders in patients with noncardiac chest pain: Psychiatric morbidity linked with increased pain and health care utilization. 
  • Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. 
  • Myocardial infarction rule-out in the emergency department: are high-sensitivity troponins the answer?: comment on "One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T". 
  • Navigating the scylla and charybdis of chest pain management in the emergency department. Is a computer the answer? 
  • Necessity of hospitalization and stress testing in low risk chest pain patients. 
  • Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. The Economics of Noninvasive Diagnosis (END) Study Group. 
  • Outcomes of anatomical versus functional testing for coronary artery disease. 
  • PROspective Multicenter Imaging Study for Evaluation of chest pain: rationale and design of the PROMISE trial. 
  • Pain catastrophizing in patients with noncardiac chest pain: relationships with pain, anxiety, and disability. 
  • Pathologic quiz case: a 53-year-old man with chest pain and cough. Malignant (diffuse) pleural mesothelioma, biphasic variant, with heterologous differentiation. 
  • Patient, physician and geographic predictors of cardiac stress testing strategy in Ontario, Canada: a population-based study. 
  • Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination. 
  • Patterns of Emergency Care for Possible Acute Coronary Syndrome Among Patients with Chest Pain or Shortness of Breath at a Tanzanian Referral Hospital. 
  • Perceptions of chest pain and healthcare seeking behavior for chest pain in northern Tanzania: A community-based survey. 
  • Performance of a population-based cardiac risk stratification tool in Asian patients with chest pain. 
  • Peripartum cardiomyopathy presenting as an acute myocardial infarction. 
  • Physician judgement in predicting obstructive coronary artery disease and adverse events in chest pain patients. 
  • Pitfalls of chest pain. Pseudoxanthoma elasticum. 
  • Presenting Symptoms in Patients Undergoing Coronary Artery Disease Evaluation: Association With Noninvasive Test Results and Clinical Outcomes in the PROMISE Trial. 
  • Pretest probability for patients with suspected obstructive coronary artery disease: re-evaluating Diamond-Forrester for the contemporary era and clinical implications: insights from the PROMISE trial. 
  • Prevalence and clinical implications of persistent or exertional cardiopulmonary symptoms following SARS-CoV-2 infection in 3597 collegiate athletes: a study from the Outcomes Registry for Cardiac Conditions in Athletes (ORCCA). 
  • Prevalence of Abnormal Coronary Findings on Coronary Computed Tomography Angiography Among Young Adults Presenting With Chest Pain. 
  • Prognosis is worse with elevated cardiac troponin in nonacute coronary syndrome compared with acute coronary syndrome. 
  • Prognostic Value of Coronary CTA in Stable Chest Pain: CAD-RADS, CAC, and Cardiovascular Events in PROMISE. 
  • Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain: Insights From the PROMISE Trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain). 
  • Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome. 
  • Prognostic value of isolated troponin elevation across the spectrum of chest pain syndromes. 
  • Providing Rapid Out of Hospital Acute Cardiovascular Treatment 4 (PROACT-4). 
  • Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin. 
  • Rapidly progressing mycotic aortic aneurysm masquerading as acute coronary syndrome. 
  • Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules. 
  • Relation of platelet activation and myocardial ischemia biomarkers dependent on type of chest pain (abrupt onset versus intermittent) in patients with angina pectoris or non-Q-wave acute myocardial infarction. 
  • Reply to "Letter to the Editor, re: GRACE-2: Low-Risk, Recurrent Abdominal Pain in the Emergency Department". 
  • Reply: hs-cTnI in Stable Chest Pain. 
  • Risk stratification in chest pain patients undergoing nuclear stress testing: the Erlanger Stress Score. 
  • Risk stratification in patients with chest pain. 
  • Risk stratification in patients with chest pain. 
  • Risk-benefit trade-offs in revascularisation choices. 
  • Role of noninvasive testing in the clinical evaluation of women with suspected ischemic heart disease: a consensus statement from the American Heart Association. 
  • Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department. 
  • Screening for panic-related anxiety in emergency department patients with cardiopulmonary complaints: A comparison of two self-report instruments. 
  • Self-report of chest pain symptoms and coronary artery disease in patients undergoing angiography. 
  • Serial sampling of copeptin levels improves diagnosis and risk stratification in patients presenting with chest pain: results from the CHOPIN trial. 
  • Sex Differences in Functional and CT Angiography Testing in Patients With Suspected Coronary Artery Disease. 
  • Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review. 
  • Simplified Predictive Instrument to Rule Out Acute Coronary Syndromes in a High-Risk Population. 
  • Small whole heart volume predicts cardiovascular events in patients with stable chest pain: insights from the PROMISE trial. 
  • Smartphone ECG for evaluation of ST-segment elevation myocardial infarction (STEMI): Design of the ST LEUIS International Multicenter Study. 
  • Soluble P-selectin is not a surrogate marker for platelet P-selectin: evidence from a multicenter chest pain study group. 
  • Soluble PECAM-1, but not P-selectin, nor osteonectin identify acute myocardial infarction in patients presenting with chest pain. 
  • Stress cardiac MR imaging compared with stress echocardiography in the early evaluation of patients who present to the emergency department with intermediate-risk chest pain. 
  • Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association. 
  • The Impact of American College of Cardiology Chest Pain Center Accreditation on Guideline Recommended Acute Myocardial Infarction Management. 
  • The Internet Tracking Registry of Acute Coronary Syndromes (i*trACS): a multicenter registry of patients with suspicion of acute coronary syndromes reported using the standardized reporting guidelines for emergency department chest pain studies. 
  • The Puzzle of Noninvasive Testing in Women: Filling in the Pieces With the CRESCENT Trial (Calcium Imaging and Selective CT Angiography in Comparison to Functional Testing for Suspected Coronary Artery Disease). 
  • The diagnostic utility of cardiovascular magnetic resonance in patients with chest pain, elevated cardiac enzymes and non-obstructed coronary arteries. 
  • The evaluation of chest pain in women. 
  • The flow cytometer model markedly affects measurement of ex vivo whole blood platelet-bound P-selectin expression in patients with chest pain: are we comparing apples with oranges. 
  • The impact of race on the acute management of chest pain. 
  • The rational clinical examination. Is this patient having a myocardial infarction? 
  • The utility of gestures in patients with chest discomfort. 
  • Triage to Observation: A Quality Improvement Initiative for Chest Pain Patients Presenting to the Emergency Department. 
  • Triaging Primary Care Patients Referred for Chest Pain to Specialist Cardiology Centres: Efficacy of an Optimised Protocol. 
  • Troponin elevation after black widow spider envenomation. 
  • Troponins in pericarditis: implications for diagnosis and management of chest pains patients. 
  • Use of Cardiac Noninvasive Testing After Emergency Department Discharge: Association of Hospital Network Testing Intensity and Outcomes in Ontario, Canada. 
  • Use of High-Risk Coronary Atherosclerotic Plaque Detection for Risk Stratification of Patients With Stable Chest Pain: A Secondary Analysis of the PROMISE Randomized Clinical Trial. 
  • Use of multidetector computed tomography for the assessment of acute chest pain: a consensus statement of the North American Society of Cardiac Imaging and the European Society of Cardiac Radiology. 
  • Use of stellate ganglion blocks for chronic chest pain associated with primary pulmonary hypertension. 
  • Usefulness of combining necrosis and platelet markers in triaging patients presenting with chest pain to the emergency department. 
  • Utility of Dynamic Ultrasound in Diagnosing Thoracic Pain Due to Iatrogenic Slipping Rib Syndrome. 
  • Utility of observation units for young emergency department chest pain patients. 
  • Utilization of coronary computed tomography angiography for exclusion of coronary artery disease in ED patients with low- to intermediate-risk chest pain: a 1-year experience. 
  • Variation in US hospital emergency department admission rates by clinical condition. 
  • Weekend and holiday exercise testing in patients with chest pain. 
  • Wellens syndrome: a life-saving diagnosis. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Granger, Christopher Bull, Professor of Medicine, School of Nursing
  • Keefe, Francis Joseph, Professor in Psychiatry and Behavioral Sciences, Psychology & Neuroscience
  • Limkakeng Jr., Alexander Tan, Professor of Emergency Medicine, Emergency Medicine
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology