Chikungunya virus
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Subject Areas on Research
- A Systematic Meta-analysis of Immune Signatures in Patients With Acute Chikungunya Virus Infection.
- A sensitive epitope-blocking ELISA for the detection of Chikungunya virus-specific antibodies in patients.
- An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
- Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity.
- Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology.
- Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania.
- Chikungunya as a cause of acute febrile illness in southern Sri Lanka.
- Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.
- Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo.
- Chikungunya: a bending reality.
- Chimeric alphavirus vaccine candidates for chikungunya.
- Clinical evaluation of the BioFire Global Fever Panel for the identification of malaria, leptospirosis, chikungunya, and dengue from whole blood: a prospective, multicentre, cross-sectional diagnostic accuracy study.
- Comparative analysis of the genome sequences and replication profiles of chikungunya virus isolates within the East, Central and South African (ECSA) lineage.
- Distribution of Aedes mosquitoes in the Kilimanjaro Region of northern Tanzania.
- Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection.
- Early clearance of Chikungunya virus in children is associated with a strong innate immune response.
- Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.
- Immuno-biology of Chikungunya and implications for disease intervention.
- Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
- Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus.
- Sero-prevalence and cross-reactivity of chikungunya virus specific anti-E2EP3 antibodies in arbovirus-infected patients.
- Seroprevalence of antibodies against chikungunya virus in Singapore resident adult population.
- Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus.
- Trisubstituted Thieno[3,2-b]pyrrole 5-Carboxamides as Potent Inhibitors of Alphaviruses.
- Unique epitopes recognized by antibodies induced in Chikungunya virus-infected non-human primates: implications for the study of immunopathology and vaccine development.
- Zika and Chikungunya Virus and Risk for Venous Thromboembolism.