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Subject Areas on Research
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A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis.
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A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
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A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production.
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Analytical Evaluation of the Abbott RealTime CT/NG Assay for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Swabs.
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Antichlamydial antibodies, human fertility, and pregnancy wastage.
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CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity.
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Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.
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Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor.
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Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection.
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Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.
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Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events.
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Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.
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Chlamydia trachomatis immune evasion via downregulation of MHC class I surface expression involves direct and indirect mechanisms.
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Chlamydia trachomatis masquerading as a chronic allergic conjunctivitis.
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Chlamydia trachomatis-infected cells and uninfected-bystander cells exhibit diametrically opposed responses to interferon gamma.
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Chlamydia trachomatis.
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Chlamydial intracellular survival strategies.
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Clinical trial experience with prophylactic human papillomavirus 6/11/16/18 vaccine in young black women.
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Comparing the prevalence of chlamydial infection across populations--what is appropriate?
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Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
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Direct fluorescent antibody testing for endocervical Chlamydia trachomatis: factors affecting accuracy.
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Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis.
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Expression of CD1d and ligand-induced cytokine production are tissue specific in mucosal epithelia of the human lower reproductive tract.
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Forward and Reverse Genetic Analysis of Chlamydia.
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Genetic analysis of susceptibility to Chlamydia trachomatis in mouse.
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Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
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Hidden epidemic of sexually transmitted diseases in China: crisis and opportunity.
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Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii.
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IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.
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Immunopathogenesis of genital Chlamydia infection: insights from mouse models.
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Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.
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Inhibition of the futalosine pathway for menaquinone biosynthesis suppresses Chlamydia trachomatis infection.
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Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix.
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Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Chlamydia trachomatis Virulence-Associated Protease CPAF.
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Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia.
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Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis.
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Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.
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Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease.
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Modulation of MICA on the surface of Chlamydia trachomatis-infected endocervical epithelial cells promotes NK cell-mediated killing.
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Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity.
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N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF.
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Pathogen Evasion of Chemokine Response Through Suppression of CXCL10.
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Pelvic inflammatory disease.
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Potential mechanisms for increased HIV-1 transmission across the endocervical epithelium during C. trachomatis infection.
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Predicting adolescents' longitudinal risk for sexually transmitted infection: results from the National Longitudinal Study of Adolescent Health.
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Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms.
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Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches.
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Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.
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Simultaneous Evaluation of Diagnostic Assays for Pharyngeal and Rectal Neisseria gonorrhoeae and Chlamydia trachomatis Using a Master Protocol.
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The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence.
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The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs.
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The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins.
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The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling.
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The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.
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The Expanding Molecular Genetics Tool Kit in Chlamydia.
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The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction.
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The easiest children to reach are most likely to be infected with ocular Chlamydia trachomatis in trachoma endemic areas of Niger.
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The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice.
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Trachoma: an update on prevention, diagnosis, and treatment.
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Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.
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cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.
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Keywords of People