Cholesterol

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  Subject Areas on Research

  • 10 questions about statins and stroke. 
  • 2013 American College of Cardiology/American Heart Association and 2004 Adult Treatment Panel III cholesterol guidelines applied to HIV-infected patients with/without subclinical high-risk coronary plaque. 
  • 27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling. 
  • A carrageenan hydrogel stabilized colloidal gold multi-enzyme biosensor electrode utilizing immobilized horseradish peroxidase and cholesterol oxidase/cholesterol esterase to detect cholesterol in serum and whole blood. 
  • A comparison of methods for the estimation of plasma low- and very low-density lipoprotein cholesterol. The Lipid Research Clinics Prevalence Study. 
  • A comparison of tacrolimus and cyclosporine in liver transplantation: effects on renal function and cardiovascular risk status. 
  • A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia. 
  • A comparsion of polyurethane and silastic artificial hearts in 10 long survival experiments in calves. 
  • A cross-sectional study of human serum sphingolipids, diet and physiologic parameters. 
  • A dynamic analysis of chronic disease development: a study of sex specific changes in coronary heart disease incidence and risk factors in Framingham. 
  • A randomized trial examining the effectiveness of switching from olanzapine, quetiapine, or risperidone to aripiprazole to reduce metabolic risk: comparison of antipsychotics for metabolic problems (CAMP). 
  • A systematic review of diabetes disease management programs. 
  • A telephone-delivered intervention for patients with NIDDM. Effect on coronary risk factors. 
  • A victory for statins or a defeat for diet policies? Cholesterol falls in Poland in the past decade: A modeling study. 
  • APOE epsilon4 and low cholesterol as risks for depression in a biracial elderly community sample. 
  • ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. 
  • Abnormal lipid composition of the red cell membrane in congenital dyserythropoietic anemia type II (HEMPAS). 
  • Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses. 
  • Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. 
  • Adrenal physiology and pharmacology. 
  • Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. 
  • Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. 
  • Age-related macular degeneration and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. 
  • Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. 
  • Amiodarone-liposome interaction: a multinuclear NMR and X-ray diffraction study. 
  • An electronic health record based model predicts statin adherence, LDL cholesterol, and cardiovascular disease in the United States Military Health System. 
  • Analysis of the components of CHD risk in the Framingham study: new multivariate procedures for the analysis of chronic disease development. 
  • Anthropometric assessment of 10-y changes in body composition in the elderly. 
  • Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys. 
  • Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C. 
  • Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy. 
  • Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. 
  • Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. 
  • Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies. 
  • Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner. 
  • Applicability and potential clinical effects of 2013 cholesterol guidelines on major cardiovascular events. 
  • Application of new cholesterol guidelines to a population-based sample. 
  • Assessing the accuracy of a point-of-care analyzer for hyperlipidaemia in western Kenya. 
  • Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 
  • Association of cortisol and the metabolic syndrome in Korean men and women. 
  • Associations between cardiovascular risk factors and early age-related macular degeneration in a rural Chinese adult population. 
  • Atheroembolic involvement of renal allografts. 
  • Autophagy links inflammasomes to atherosclerotic progression. 
  • B cell depletion reduces the development of atherosclerosis in mice. 
  • Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains. 
  • Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E. 
  • Bed rest worsens impairments in fat and glucose metabolism in older, overweight adults. 
  • Beneficial effects of pinacidil on blood lipids: comparisons with prazosin and placebo in patients with hypertension. Pinacidil-Prazosin and Pinacidil-Placebo Research Groups, Lilly Research Laboratories. 
  • Bilayer interfacial properties modulate the binding of amphipathic peptides. 
  • Bile compositional changes and cholesterol stone formation following orthotopic liver transplantation. 
  • Biliary response to glucagon and insulin following hepatic transplantation in humans. 
  • Biliary response to glucagon in humans. 
  • Biliary secretion of extracorporeal porcine livers with single and dual vessel perfusion. 
  • Biobehavioral basis of coronary-prone behavior in middle-age men. Part II: Serum cholesterol, the Type A behavior pattern, and hostility as interactive modulators of physiological reactivity. 
  • Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies. 
  • Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial. 
  • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. 
  • CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer. 
  • Caffeine and cholesterol: interactions with hostility. 
  • Can lay-led walking programmes increase physical activity in middle aged adults? A randomised controlled trial. 
  • Cardiovascular risk factors, inflammation, and corneal arcus: the singapore malay eye study. 
  • Cardiovascular risk profile earlier in life and Medicare costs in the last year of life. 
  • Changes in Medical Management after Coronary CT Angiography. 
  • Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics. 
  • Changes in incidence of diabetes mellitus-related eye disease among US elderly persons, 1994-2005. 
  • Changes in lipid profile of patients referred to a cardiac rehabilitation program. 
  • Changes in lipid profiles of liver microsomes of rats following intratracheal administration of DDT or endosulfan. 
  • Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon). 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Cholesterol and breast cancer pathophysiology. 
  • Cholesterol controversy--where do we go from here? 'Toward healthful diets' reevaluated. 
  • Cholesterol curves to identify population norms by age and sex in healthy weight children. 
  • Cholesterol feeding reduces vascular endothelial growth factor signaling in rabbit corporal tissues. 
  • Cholesterol granuloma of the breast mimicking carcinoma: report of a case. 
  • Cholesterol granuloma of the lateral ventricle. Case report. 
  • Cholesterol interaction with the daunorubicin binding site of P-glycoprotein. 
  • Cholesterol metabolism in cultured fibroblasts in adrenoleukodystrophy. 
  • Cholesterol metabolism in non-obese women--Failure of physical conditioning to alter levels of high density lipoprotein cholesterol. 
  • Cholesterol modifies the short-range repulsive interactions between phosphatidylcholine membranes. 
  • Cholesterol-fed and casein-fed rabbit models of atherosclerosis. Part 2: Differing morphological severity of atherogenesis despite matched plasma cholesterol levels. 
  • Clinical and angiographic correlates of short- and long-term mortality in patients undergoing coronary artery bypass grafting. 
  • Coexisting endogenous lipoid pneumonia, cholesterol granulomas, and pulmonary alveolar proteinosis in a pediatric population: a clinical, radiographic, and pathologic correlation. 
  • Comparison of Nonblood-Based and Blood-Based Total CV Risk Scores in Global Populations. 
  • Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines. 
  • Comparison of proximate composition and fatty acid and cholesterol content of lean and typical commercial pork. 
  • Competitive, reversible inhibition of cytosolic phospholipase A2 at the lipid-water interface by choline derivatives that partially partition into the phospholipid bilayer. 
  • Conversion to atorvastatin in patients intolerant or refractory to simvastatin therapy: the CAPISH study. 
  • Corneal arcus is a sign of cardiovascular disease, even in low-risk persons. 
  • Coronary heart disease risk in patients with stroke or transient ischemic attack and no known coronary heart disease: findings from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Correlates of serum lutein + zeaxanthin: findings from the Third National Health and Nutrition Examination Survey. 
  • Cumulative deficits and physiological indices as predictors of mortality and long life. 
  • Cutaneous cholesterol embolism of the lower extremities. 
  • Decreases in free cholesterol and fatty acid unsaturation in renal cell carcinoma demonstrated by breath-hold magnetic resonance spectroscopy. 
  • Delivery of glucose-6-phosphatase in a canine model for glycogen storage disease, type Ia, with adeno-associated virus (AAV) vectors. 
  • Depletion of plasma membrane cholesterol dampens hydrostatic pressure and shear stress-induced mechanotransduction pathways in osteoblast cultures. 
  • Determination of high density lipoprotein-cholesterol in stored human plasma. 
  • Development of the lipid-rich core in human atherosclerosis. 
  • Diagnostic accuracy and pitfalls of [iodine-131]6-beta-iodomethyl-19-norcholesterol (NP-59) imaging. 
  • Differential association of serum lipids with diabetic retinopathy and diabetic macular edema. 
  • Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study. 
  • Differential changes in plasma high-density lipoprotein-cholesterol levels in obese men and women during weight reduction. 
  • Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. 
  • Direct, progressive association of cardiovascular risk factors with incident proteinuria: results from the Korea Medical Insurance Corporation (KMIC) study. 
  • Distinct electric potentials in soma and neurite membranes. 
  • Do healthy adults need to know their cholesterol level? 
  • Dubowitz syndrome: a defect in the cholesterol biosynthetic pathway? 
  • Dysregulation of distal cholesterol biosynthesis in association with relapse and advanced disease in CHC genotype 2 and 3 treated with sofosbuvir and ribavirin. 
  • EUR-1008 pancreatic enzyme replacement is safe and effective in patients with cystic fibrosis and pancreatic insufficiency. 
  • Effect of 6-month adherence to a very low carbohydrate diet program. 
  • Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. I. Proteins, lipids, triglycerides and cholesterol. 
  • Effect of dietary fat saturation and cholesterol on low density lipoprotein degradation by mononuclear cells of Cebus monkeys. 
  • Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trial. 
  • Effect of dihydrostreptomycin on tissue lipid of guinea-pigs. 
  • Effect of ezetimibe/simvastatin compared with atorvastatin on lipoprotein subclasses in patients with type 2 diabetes and hypercholesterolaemia. 
  • Effect of feeding excess of vitamin A and vitamin C on liver, plasma and adrenal lipids of rats. 
  • Effect of gamma irradiation and cystamine on kidney lipids of rats. 
  • Effect of glucagon and insulin upon biliary lipid secretion. 
  • Effect of hepatic artery flow on bile secretory function after cold ischemia. 
  • Effect of hypervitaminosis A on intestinal lipids of rats. 
  • Effect of perfusion pressure upon uptake and biosynthesis of arterial lipids. 
  • Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients. 
  • Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis. 
  • Effects of dibutyryl cyclic AMP and theophylline on biliary cholesterol secretion. 
  • Effects of dietary pectin and cellulose on hepatic and intestinal mixed-function oxidations and hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the rat. 
  • Effects of exercise on the Type A (coronary prone) behavior pattern. 
  • Effects of exercise training on ventricular function in patients with recent myocardial infarction. 
  • Effects of fat supplementation and immature alfalfa to concentrate ratio on plasma progesterone, energy balance and reproductive traits of dairy cattle. 
  • Effects of heparin and cardiac catheterization on serum lipoprotein and triglyceride levels. 
  • Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. 
  • Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials. 
  • Effects of monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids in hamsters. 
  • Effects of natural and enantiomeric cholesterol on the thermotropic phase behavior and structure of egg sphingomyelin bilayer membranes. 
  • Effects of nurse-managed protocols in the outpatient management of adults with chronic conditions: a systematic review and meta-analysis. 
  • Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level. 
  • Effects of the amount and intensity of exercise on plasma lipoproteins. 
  • Efficacy and Safety of Alternate-Day Versus Daily Dosing of Statins: a Systematic Review and Meta-Analysis. 
  • Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia. 
  • Efficacy of provitamin A carotenoids in reversing vitamin A deficiency induced lesions in brain lipids of chicks. 
  • Elastic deformation and failure of lipid bilayer membranes containing cholesterol. 
  • Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility. 
  • Emerging risk factors as markers for carotid intima media thickness scores. 
  • Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy. 
  • Estimating lifetime risk of developing high serum total cholesterol: adjustment for baseline prevalence and single-occasion measurements. 
  • European and American Blood Cholesterol Guidelines Result in Similar Rates of Statin Recommendations when Applied to a Country with High Cardiovascular Disease Risk 
  • Evaluation and clinical application of a direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlipidemic adults. 
  • Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model. 
  • Evidence for the role of cell stiffness in modulation of volume-regulated anion channels. 
  • Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis. 
  • Factors influencing the lipid response to selective alpha 1-inhibition. 
  • Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. 
  • Female steroid hormones and lipoprotein synthesis in the cockerel: effects of progesterone and nafoxidine on the estrogenic stimulation of very low density lipoproteins (VLDL) synthesis. 
  • Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling. 
  • Flicker light-induced retinal vasodilation in diabetes and diabetic retinopathy. 
  • Florida's response to the Physician's National Cholesterol Education Program. 
  • Focal increases in vascular cell adhesion molecule-1 and intimal macrophages at atherosclerosis-susceptible sites in the rabbit aorta after short-term cholesterol feeding. 
  • Frequency of hypothyroidism in adults with serum total cholesterol levels > 200 mg/dl. 
  • Frequency of low serum high-density lipoprotein cholesterol levels in hospitalized patients with "desirable" total cholesterol levels. 
  • Frequency of physical activity, exercise capacity, and atherosclerotic heart disease risk factors in male police officers. 
  • Fructose consumption as a risk factor for non-alcoholic fatty liver disease. 
  • Functional capacity in men and women following cardiac rehabilitation. 
  • Gallbladder Na+/H+ exchange activity is up-regulated prior to cholesterol crystal formation. 
  • Gallstone formation during weight-reduction dieting. 
  • Gender differences in cholesterol nucleation in native bile: estrogen is a potential contributory factor. 
  • Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. 
  • Glucagon or insulin suppressed biliary lipid excretion in dog and man. 
  • Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts. 
  • Glycemic and blood pressure control in an asian malay population with diabetes and diabetic retinopathy. 
  • Guidelines for overweight in adolescent preventive services: recommendations from an expert committee. The Expert Committee on Clinical Guidelines for Overweight in Adolescent Preventive Services. 
  • Health beliefs and desire to improve cholesterol levels among patients with hyperlipidemia. 
  • Hemodynamic stress and experimental aortoiliac atherosclerosis. 
  • Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway. 
  • Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. 
  • High cholesterol feeding in C57/Blc6 mice alters expression within the VEGF receptor-ligand family in corporal tissue. 
  • High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old. 
  • High-density lipoprotein subfractions. 
  • High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDL. 
  • Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. 
  • Human visceral leishmaniasis: decrease in serum cholesterol as a function of splenic parasite load. 
  • Hypercholesterolemia in rats with chronic renal insufficiency not aggravated by recombinant human growth hormone. 
  • Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. 
  • Hypocholesterolemia during mixed manic episodes. 
  • Identification and comparative analysis of hepatitis C virus-host cell protein interactions. 
  • Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel. 
  • Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. 
  • Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. 
  • Impaired Myelination in rats given excess vitamin A postnatally. 
  • Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels. 
  • Increases in serum sphingomyelin by 17 beta-estradiol. 
  • Influence of cholesterol on water penetration into bilayers. 
  • Influence of diabetes on macular thickness measured using optical coherence tomography: the Singapore Indian Eye Study. 
  • Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved model membrane vesicles: "nature's own" fusogenic lipid bilayer. 
  • Influence of platelet reactivity and inflammation on peri-procedural myonecrosis in East Asian patients undergoing elective percutaneous coronary intervention. 
  • Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial. 
  • Inhibition of bile flow by intravenous arginine hydrochloride. 
  • Inhibition of cholesterol transport in an intestine cell model by pine-derived phytosterols. 
  • Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant. 
  • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. 
  • Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode. 
  • Interaction of ethanol, cholesterol and vitamin A on phospholipid methylation in hepatic microsomes of rats. 
  • Interaction of halothane with lipid bilayers. 
  • Interaction of vitamin A and cortisol on liver and plasma lipids of rats. 
  • Interactions between poly(2-ethylacrylic acid) and lipid bilayer membranes: effects of cholesterol and grafted poly(ethylene glycol). 
  • Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers. 
  • Intima-media thickness and age of first depressive episode. 
  • Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. 
  • Ion channel behavior of amphotericin B in sterol-free and cholesterol- or ergosterol-containing supported phosphatidylcholine bilayer model membranes investigated by electrochemistry and spectroscopy. 
  • Is PSA related to serum cholesterol and does the relationship differ between black and white men? 
  • Jumping to rafts: gatekeeper role of bilayer elasticity. 
  • Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort. 
  • Lateral diffusion in planar lipid bilayers. 
  • Leishmania donovani infection enhances lateral mobility of macrophage membrane protein which is reversed by liposomal cholesterol. 
  • Linear mixed models with flexible distributions of random effects for longitudinal data. 
  • Lipid metabolism in hypervitaminosis A. 
  • Lipid requirements for leukocyte chemotaxis and phagocytosis: effects of inhibitors of phospholipid and cholesterol synthesis. 
  • Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis. 
  • Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization. 
  • Liver transplantation for glycogen storage disease type Ia. 
  • Longitudinal changes in serum cholesterol in man: an epidemiologic search for an etiology. 
  • Lovastatin increases exercise-induced skeletal muscle injury. 
  • Lovastatin therapy for hypercholesterolemia in cardiac transplant recipients. 
  • Low-density lipoprotein 4: a novel predictor of coronary artery disease severity. 
  • MR spectroscopy of cholesteryl ester in human atherosclerosis. 
  • Major eye diseases and risk factors associated with systemic hypertension in an adult Chinese population: the Beijing Eye Study. 
  • Mechanical property studies of human gallstones. 
  • Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores. 
  • Metabolic and behavioral effects of a high-sucrose diet during weight loss. 
  • Metabolic effects and efficacy of a triphasic oral contraceptive (norgestimate/ethinyl estradiol). 
  • Metabolic effects associated with atypical antipsychotic treatment in the developmentally disabled. 
  • Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases. 
  • Metabolic syndrome and alanine aminotransferase: a global perspective from the NAVIGATOR screening population. 
  • Middle fossa approach for total resection of petrous apex cholesterol granulomas: use of vascularized galeofascial flap preventing recurrence. 
  • Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis. 
  • Migration and gout: the Tokelau Island migrant study. 
  • Modification of postprandial hyperglycemia with insulin lispro improves glucose control in patients with type 2 diabetes. 
  • Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. 
  • Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. 
  • Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid. 
  • Obesity, cholesterol metabolism, and breast cancer pathogenesis. 
  • Organization of skin stratum corneum extracellular lamellae: diffraction evidence for asymmetric distribution of cholesterol. 
  • Origins of fecal neutral steroids in rats. 
  • Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. 
  • Pathways-driven sparse regression identifies pathways and genes associated with high-density lipoprotein cholesterol in two Asian cohorts. 
  • Patient-provider internet portals--patient outcomes and use. 
  • Peripheral metabolic actions of leptin. 
  • Physical activity, television viewing time, and retinal vascular caliber. 
  • Physical conditioning augments the fibrinolytic response to venous occlusion in healthy adults. 
  • Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. 
  • Plasma lipoproteins of free-ranging howling monkeys (Alouatta palliata). 
  • Platelet reactivity and thrombogenicity in postmenopausal women. 
  • Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. 
  • Poor oral health is associated with coronary heart disease and elevated systemic inflammatory and haemostatic factors. 
  • Population Effect of Differences in Cholesterol Guidelines in Eastern Europe and the United States. 
  • Porcine hepatic phospholipid efflux during reperfusion after cold ischemia. 
  • Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction. 
  • Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey. 
  • Prevalences of type 2 diabetes, the insulin resistance syndrome, and coronary heart disease in an elderly, biethnic population. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • Prognostic significance of serum total cholesterol and triglyceride levels in patients hospitalized for heart failure with reduced ejection fraction (from the EVEREST Trial). 
  • Protein kinase stimulation of a reconstituted cholesterol side chain cleavage enzyme system in the bovine corpus luteum. 
  • Psychosocial correlates of atrial natriuretic peptide: a marker of vascular health. 
  • Pulmonary cholesterol granulomas in patients with pulmonary artery hypertension: chest radiographic and CT findings. 
  • Quality & quantity of dietary protein & acute endosulphan metabolic toxicity in rat liver microsomes. 
  • RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. 
  • Racial Differences in the Association Between Preoperative Serum Cholesterol and Prostate Cancer Recurrence: Results from the SEARCH Database. 
  • Radioprotection of whole-body gamma irradiation induced alterations in lipid metabolism of liver and plasma by AET (S-2, aminoethyl isothiuronium Br. H. Br.) and serotonin in rats. 
  • Range of the solvation pressure between lipid membranes: dependence on the packing density of solvent molecules. 
  • Recall of three heart disease risk factor diagnoses among low-income women. 
  • Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner. 
  • Reduction of intimal hyperplasia and enhanced reactivity of experimental vein bypass grafts with verapamil treatment. 
  • Reduction of ischemic events in Improved Reduction of Outcomes: Vytorin Efficacy International Trial: Intensive cholesterol lowering or ezetimibe antithrombotic effects? 
  • Regression of atherosclerosis in monkeys reduces vascular superoxide levels. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. 
  • Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy. 
  • Relations of trait depression and anxiety to low lipid and lipoprotein concentrations in healthy young adult women. 
  • Relationship between diabetic retinopathy, diabetic macular oedema and erectile dysfunction in type 2 diabetics. 
  • Relative and cumulative effects of lipid and blood pressure control in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels trial. 
  • Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study. 
  • Retinal arteriolar tortuosity is associated with retinopathy and early kidney dysfunction in type 1 diabetes. 
  • Retinal arteriolar wall signs and early age-related macular degeneration: the singapore malay eye study. 
  • Retinal vascular caliber and age-related macular degeneration in an Indian population from Singapore. 
  • Retinal vessel diameters and the incidence of gross proteinuria and renal insufficiency in people with type 1 diabetes. 
  • Retinol and adrenal lipids of rats. 
  • Risk of stroke and cardiovascular events after ischemic stroke or transient ischemic attack in patients with type 2 diabetes or metabolic syndrome: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Role for Nox1 NADPH oxidase in atherosclerosis. 
  • Role of cyclic AMP in the actions of luteinizing hormone on steroidogenesis in the corpus luteum. 
  • SERUM LIPIDS IN LEPROSY BY SILICIC ACID COLUMN CHROMATOGRAPHY. 
  • Screening for diabetes in an outpatient clinic population. 
  • Seasonal variations in the pattern of lipids in the sexual segment, kidney and liver of the Indian house lizard, Hemidactylus flaviviridis Ruppell. 
  • Separation & estimation of human serum lipids by silicic acid column chromatography. 
  • Serum Cholesterol Levels within the High Normal Range Are Associated with Better Cognitive Performance among Chinese Elderly. 
  • Serum cholesterol in patients undergoing cardiac catheterization for suspected coronary artery disease: diagnostic and prognostic implications. 
  • Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer. 
  • Serum cholesterol reduction with tamoxifen. 
  • Serum enzyme alterations in hypothyroidism before and after treatment. 
  • Serum lipid profile and risk of prostate cancer recurrence: Results from the SEARCH database. 
  • Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants. 
  • Short-term change in body mass index in overweight adolescents following cholesterol screening. 
  • Smoking, cardiovascular risk factors, and age-related macular degeneration in Asians: the Singapore Malay Eye Study. 
  • Sorting of lens aquaporins and connexins into raft and nonraft bilayers: role of protein homo-oligomerization. 
  • Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts. 
  • Spleen lipids: effect of whole body gamma irradiation and radioprotective chemicals. 
  • Statin Utilization and Recommendations Among HIV- and HCV-infected Veterans: A Cohort Study. 
  • Statin treatment and stroke outcome in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Stimulation of cholesterogenesis by ascorbic acid in adrenal of rats fed vitamin A. 
  • Structure and cohesive properties of sphingomyelin/cholesterol bilayers. 
  • Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts. 
  • Studies on mode of action of vitamin A. 
  • Surface ripples cause the large fluid spaces between gel phase bilayers containing small amounts of cholesterol. 
  • Synergistic effects of exposure to concentrated ambient fine pollution particles and nitrogen dioxide in humans. 
  • Synthesis and characterization of carbohydrate-based phospholipids. 
  • Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. 
  • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. 
  • The Cholesterol, Hypertension, And Glucose Education (CHANGE) study: results from a randomized controlled trial in African Americans with diabetes. 
  • The DASH diet and blood pressure. 
  • The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos. 
  • The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor. 
  • The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. 
  • The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. 
  • The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. 
  • The arterial wall and the atherosclerotic lesion. 
  • The effect of body mass and diet composition on torpor patterns in a Malagasy primate (Microcebus murinus). 
  • The effect of cholesterol on the structure of phosphatidylcholine bilayers. 
  • The effect of hypercholesterolemia on early atherosclerotic lesions initiated by fibrinopeptide B. 
  • The effects of liver denervation on the regulation of hepatic biliary secretion. 
  • The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer. 
  • The impact of medication use in a multicomponent intervention: results from the WISEWOMAN program. 
  • The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. 
  • The lipids of the erythrocyte in paroxysmal nocturnal hemoglobinuria. 
  • The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. 
  • The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. 
  • The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. 
  • The prevalence of and risk factors for pterygium in an urban Malay population: the Singapore Malay Eye Study (SiMES). 
  • The primary empty sella: clinical and radiographic characteristics and endocrine function. 
  • The relationship between albuminuria and hypercholesterolemia. 
  • The relationship between cholesterol level and myocardial infarction or mortality risk in patients with coronary artery disease. A report from the Coronary Artery Surgery Study (CASS) registry. 
  • The relationship of retinopathy in persons without diabetes to the 15-year incidence of diabetes and hypertension: Beaver Dam Eye Study. 
  • The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation. 
  • The role of lipid-related genes, aging-related processes, and environment in healthspan. 
  • The sources of rat biliary cholesterol and bile acid. 
  • The water permeability of lens aquaporin-0 depends on its lipid bilayer environment. 
  • Theoretical analysis of lipid transport in sciatic nerve. 
  • Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers. 
  • Three-year incidence and cumulative prevalence of retinopathy: the atherosclerosis risk in communities study. 
  • Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells. 
  • Time-varying covariates in models of human mortality and aging: multidimensional generalizations of the Gompertz. 
  • Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. 
  • Transitional features in human atherosclerosis. Intimal thickening, cholesterol clefts, and cell loss in human aortic fatty streaks. 
  • Turnover of pancreas phospholipids in rats fed inadequate dietary protein. 
  • Two-year trends in physical performance following supervised exercise among community-dwelling older veterans. 
  • Type A behavior pattern and coronary atherosclerosis. 
  • Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. 
  • U.S.S.R. and U.S. nutrient intake, plasma lipids, and lipoproteins in men ages 40-59 sampled from Lipid Research Clinics populations. 
  • Ultrasonic attenuation measurements in phospholipid dispersions. 
  • Ultrastructural findings in skin from patients with Niemann-Pick disease, type C. 
  • Use of ketoconazole to probe the pathogenetic importance of 1,25-dihydroxyvitamin D in absorptive hypercalciuria. 
  • Usefulness of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) in Women to Lower Triglyceride Levels (Results from the MARINE and ANCHOR Trials). 
  • Variability in cholesterol measurements in a worksite cholesterol screening program. 
  • Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. 
  • Vascular nutritional correlates of late-life depression. 
  • Vitamin A in liposomes. Inhibition of complement binding and alteration of membrane structure. 
  • Water permeability of aquaporin-4 channel depends on bilayer composition, thickness, and elasticity. 
  • X-ray diffraction analysis of isolated skin lipids: reconstitution of intercellular lipid domains. 
  • X-ray diffraction to determine the thickness of raft and nonraft bilayers. 
  • Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months. 
• 

  Keywords of People

  • Bowes Rickman, Catherine, Professor of Ophthalmology, Cell Biology
  • Craciunescu, Oana, Associate Professor of Radiation Oncology, Radiation Oncology
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Peterson, Eric David, Fred Cobb, M.D. Professor of Medicine, Medicine, Cardiology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Professor of Urology, Surgery
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Shaw, Ryan, Elizabeth C. Clipp Term Chair of Nursing, Duke Innovation & Entrepreneurship
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Ulmer, Christi S, Assistant Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine
  • Yancy Jr., William Samuel, Associate Professor of Medicine, Medicine, General Internal Medicine