Chondroitin Sulfates
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Subject Areas on Research
- "Heparin-free" cardiopulmonary bypass: first reported use of heparinoid (Org 10172) to provide anticoagulation for cardiopulmonary bypass.
- A dose escalation study of ORG 10172 (low molecular weight heparinoid) in stroke.
- A straightforward, quantitative ultra-performance liquid chromatography-tandem mass spectrometric method for heparan sulfate, dermatan sulfate and chondroitin sulfate in urine: an improved clinical screening test for the mucopolysaccharidoses.
- Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
- Analysis of glycosaminoglycans in cerebrospinal fluid from patients with mucopolysaccharidoses by isotope-dilution ultra-performance liquid chromatography-tandem mass spectrometry.
- Antithrombotic treatment of ischemic stroke among patients with occlusion or severe stenosis of the internal carotid artery: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
- Aortic glycosaminoglycans in atherosclerosis-susceptible and -resistant pigeons.
- Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study.
- Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
- CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension.
- Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo.
- Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor.
- Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells.
- Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells.
- Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules.
- Circadian variation in ischemic stroke subtypes.
- Coagulation complicating cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia receiving the heparinoid, danaparoid sodium.
- Collagen-chondroitin sulphate-hydroxyapatite porous composites: a histochemical and electron microscopy approach.
- Comparison of native porcine skin and a dermal substitute using tensiometry and digital image speckle correlation.
- Crustacean peptide and peptide-like pheromones and kairomones.
- Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans.
- Descemet-stripping automated endothelial keratoplasty: effect of anterior lamellar corneal tissue-on/-off storage condition on Descemet-stripping automated endothelial keratoplasty donor tissue.
- Design of the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
- Dexamethasone-coated neural probes elicit attenuated inflammatory response and neuronal loss compared to uncoated neural probes.
- Differences between anterior and posterior circulation stroke in TOAST.
- Donor factors associated with epithelial defects after penetrating keratoplasty.
- Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulfate-rich interfaces.
- Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (delta-f508) cystic fibrosis transmembrane conductance regulator.
- Effect of hyaluronic acid/chondroitin sulfate on healing of full-thickness tendon lacerations in rabbits.
- Effect of prior aspirin use on stroke severity in the trial of Org 10172 in acute stroke treatment (TOAST).
- Ensuring reliability of outcome measures in multicenter clinical trials of treatments for acute ischemic stroke. The program developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
- Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes.
- Evolutionary conservation of heavy chain protein transfer between glycosaminoglycans.
- Extracellular matrix disruption and pain after eccentric muscle action.
- Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin.
- Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort.
- Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint.
- Group index of the human cornea at 1.3-microm wavelength obtained in vitro by optical coherence domain reflectometry.
- Heparin induced thrombocytopenia: diagnosis and contemporary antithrombin management.
- Heparin-induced thrombocytopenia: pathophysiology and management.
- Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria.
- Kinetic analysis of the effects of glycosaminoglycans and lipoproteins on urokinase-mediated plasminogen activation.
- Large-dose infusions of heparinoid ORG 10172 in ischemic stroke.
- Laser-assisted indocyanine green dye angiography accurately predicts the split-thickness graft timing of integra artificial dermis.
- Light and electron microscopy characterization of a collagen-liposome-entrapped chondroitin sulfate composite as intra-articular drug delivery system.
- Liposomal formulation of chondroitin sulfate enhances its antioxidant and anti-inflammatory potential in L929 fibroblast cell line.
- Liposomes-entrapped chondroitin sulphate: ultrastructural characterization and in vitro biocompatibility.
- Long term response in a patient with neoplastic meningitis secondary to melanoma treated with (131)I-radiolabeled antichondroitin proteoglycan sulfate Mel-14 F(ab')(2): a case study.
- Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis.
- Modified technique for removal of Soemmerring ring and in-the-bag secondary intraocular lens placement in aphakic eyes.
- Monosodium urate crystal induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis?
- Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration.
- New treatment options for heparin-induced thrombocytopenia.
- Novel use of a flowable collagen-glycosaminoglycan matrix (Integra™ Flowable Wound Matrix) combined with percutaneous cannula scar tissue release in treatment of post-burn malfunction of the hand--A preliminary 6 month follow-up.
- Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.
- Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia.
- Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes.
- Quantification of glycosaminoglycans in urine by isotope-dilution liquid chromatography-electrospray ionization tandem mass spectrometry.
- Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis.
- Studies of Org 10172 in patients with acute ischemic stroke. TOAST Study Group.
- TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44.
- The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans.
- The corneal epithelium after optisol-GS storage.
- The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants.
- Use of bilayer matrix wound dressing in the exenterated socket.
- Variants in chondroitin sulfate metabolism genes in thrombotic storm.
- Will we be able to repair osteoarthritic joints? New drugs and surgical techniques for cartilage problems.
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Keywords of People
- Craciunescu, Oana, Associate Professor of Radiation Oncology, Radiation Oncology
- Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
- O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology