Chromosomes, Human, Pair 11

• 

  Subject Areas on Research

  • A 137-kb deletion within the Potocki-Shaffer syndrome interval on chromosome 11p11.2 associated with developmental delay and hypotonia. 
  • A case of infantile acute lymphoblastic leukemia presenting with rearrangement of MLL at 11q23 and apparent insertion or translocation at 10p12. 
  • A frequent human CD20 (B1) differentiation antigen DNA polymorphism detected with MspI is located near 11q12-13. 
  • A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic. 
  • A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11: distal p13 to proximal p15.1. 
  • A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. 
  • A microchromosome derived from chromosome 11 in a patient with the CREST syndrome of scleroderma. 
  • A molecular genetic linkage map of mouse chromosome 7. 
  • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. 
  • A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein. 
  • A novel chromosomal rearrangement associated with therapy-related acute leukemia. 
  • A novel sampling design to explore gene-longevity associations: the ECHA study. 
  • A pathobiological role of the insulin receptor in chronic lymphocytic leukemia. 
  • A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia. 
  • A proximal mouse chromosome 9 linkage map that further defines linkage groups homologous with segments of human chromosomes 11, 15, and 19. 
  • A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci. 
  • Adult patients with de novo acute myeloid leukemia and t(9; 11)(p22; q23) have a superior outcome to patients with other translocations involving band 11q23: a cancer and leukemia group B study. 
  • Amplification and overexpression of PPFIA1, a putative 11q13 invasion suppressor gene, in head and neck squamous cell carcinoma. 
  • An exclusion map for facioscapulohumeral (Landouzy-Déjérine) disease. 
  • An integrated physical map of 210 markers assigned to the short arm of human chromosome 11. 
  • Association of chromosome 11 locus D11S12 with histology, stage, and metastases in lung cancer. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention. 
  • Biphenotypic sarcoma with characteristics of both a Ewing sarcoma and a desmoplastic small round cell tumor. 
  • Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18. 
  • Chromosomal localization of human glutamate receptor genes. 
  • Chromosomal localization of two genes underlying late-infantile neuronal ceroid lipofuscinosis. 
  • Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization. 
  • Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. 
  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 
  • Common variants conferring risk of schizophrenia. 
  • Deletion of cyclin-dependent kinase 4 inhibitor genes P15 and P16 in non-Hodgkin's lymphoma. 
  • Delineation of the critical interval of Bardet-Biedl syndrome 1 (BBS1) to a small region of 11q13, through linkage and haplotype analysis of 91 pedigrees. 
  • Desmoplastic small round cell tumor masquerading as advanced ovarian cancer. 
  • Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis. 
  • Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1). 
  • Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. 
  • Genetic changes in human adrenocortical carcinomas. 
  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 
  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. 
  • Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. 
  • Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population. 
  • Genomic organization and cloning of the human homologue of murine Sipa-1. 
  • Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11. 
  • Identification of a new locus for autosomal recessive Charcot-Marie-Tooth disease with focally folded myelin on chromosome 11p15. 
  • Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. 
  • Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. 
  • Isolation of a paralog of the Doyne honeycomb retinal dystrophy gene from the multiple retinopathy critical region on 11q13. 
  • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. 
  • Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. 
  • Linkage of a gene causing familial focal segmental glomerulosclerosis to chromosome 11 and further evidence of genetic heterogeneity. 
  • Linkage studies in tuberous sclerosis. Chromosome 9?, 11?, or maybe 14! 
  • Localization of the photoreceptor gene ROM1 to human chromosome 11 and mouse chromosome 19: sublocalization to human 11q13 between PGA and PYGM. 
  • Loss of heterozygosity for genes on 11p and the clinical course of patients with lung carcinoma. 
  • Lymphoblastic lymphoma and excessive toxicity from chemotherapy: an unusual presentation for Fanconi anemia. 
  • MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma. 
  • Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. 
  • Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component. 
  • New chromosome 11p15 epigenotypes identified in male monozygotic twins with Beckwith-Wiedemann syndrome. 
  • Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation. 
  • Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3. 
  • Organization and evolution of alpha satellite DNA from human chromosome 11. 
  • Prenatal diagnosis of the distal 11q deletion and review of the literature. 
  • Prenatal diagnosis of the supernumerary der(22)t(11;22) syndrome associated with abnormal sonographic findings. 
  • Proliferation indices correlate with diagnosis and metastasis in diagnostically challenging melanocytic tumors. 
  • Report of the Sixth International Workshop on Human Chromosome 11 Mapping 1998. Nice, France, May 2-5, 1998. 
  • Rescue of targeted regions of mammalian chromosomes by in vivo recombination in yeast. 
  • Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. 
  • Structural organization of the human MS4A gene cluster on Chromosome 11q12. 
  • Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer. 
  • The gene that encodes the human CD20 (B1) differentiation antigen is located on chromosome 11 near the t(11;14)(q13;q32) translocation site. 
  • The generation of ordered sets of cosmid DNA clones from human chromosome region 11p. 
  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. 
  • The isolation and characterization of a novel cDNA demonstrating an altered mRNA level in nontumorigenic Wilms' microcell hybrid cells. 
  • The multiple causes of human SCID. 
  • Therapy-related acute lymphoblastic leukemia without 11q23 abnormality: report of six cases and a literature review. 
  • Three tumor-suppressor regions on chromosome 11p identified by high-resolution deletion mapping in human non-small-cell lung cancer. 
  • Tumorigenic suppression of a human cutaneous squamous cell carcinoma cell line in the nude mouse skin graft assay. 
  • Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. 
  • Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. 
  • Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. 
  • cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.