Chromosomes, Human, Pair 19

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  Subject Areas on Research

  • A Bgl II polymorphism detected by LDR152 [D19S19]. 
  • A new probe for the diagnosis of myotonic muscular dystrophy. 
  • A novel pattern of oculocerebral malformation. 
  • A small regulatory element from chromosome 19 enhances liver-specific gene expression. 
  • Adaptive evolution drives the diversification of zinc-finger binding domains. 
  • Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study. 
  • Assignment of persephin (PSPN), a human neurotrophic factor, to chromosome 19p13.3 by radiation hybrid mapping and somatic cell hybrid PCR. 
  • Association of genomic subtypes of lower-grade gliomas with shape features automatically extracted by a deep learning algorithm. 
  • Autophagy as a mechanism of antiviral defense at the maternal-fetal interface. 
  • Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling. 
  • Chromosomes with high gene density are preferentially repaired in human cells. 
  • Clinical and genetic heterogeneity in familial focal segmental glomerulosclerosis. International Collaborative Group for the Study of Familial Focal Segmental Glomerulosclerosis. 
  • Common variants at 19p13 are associated with susceptibility to ovarian cancer. 
  • Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying). 
  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. 
  • Correlation of 1p-19q-defects in human gliomas with the light microscopic appearance of oligodendroglioma. 
  • Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13. 
  • Distinct patterns of 1p and 19q alterations identify subtypes of human gliomas that have different prognoses. 
  • EKG abnormalities in pediatric patients with myotonic dystrophy. 
  • Excessive daytime somnolence and increased rapid eye movement pressure in myotonic dystrophy. 
  • Expression and trafficking of placental microRNAs at the feto-maternal interface. 
  • Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia. 
  • Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. 
  • Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. 
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. 
  • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. 
  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. 
  • Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 
  • Genomic profiles specific to patient ethnicity in lung adenocarcinoma. 
  • Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF). 
  • Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. 
  • Human placental trophoblasts confer viral resistance to recipient cells. 
  • Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. 
  • Identification of novel genes in late-onset Alzheimer's disease. 
  • Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior. 
  • Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC. 
  • Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study. 
  • Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets. 
  • Linkage and association analysis of chromosome 19q13 in multiple sclerosis. 
  • Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors. 
  • Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. 
  • Longitudinal molecular trajectories of diffuse glioma in adults. 
  • Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization. 
  • Mutations in CIC and FUBP1 contribute to human oligodendroglioma. 
  • Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. 
  • Myotonic dystrophy: update on progress to define the gene. 
  • Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV. 
  • Report of the Second International Workshop on Human Chromosome 19 mapping 1992. 
  • Report of the committee on the genetic constitution of chromosome 19. 
  • Report of the committee on the genetic constitution of chromosomes 18 and 19. 
  • Report of the committee on the genetic constitution of chromosomes 18 and 19. 
  • Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor. 
  • Review: placenta-specific microRNAs in exosomes - good things come in nano-packages. 
  • RsaI RFLP for electron transport flavoprotein-beta(ETFB). 
  • Segregation at three loci explains familial and population risk in Hirschsprung disease. 
  • The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. 
  • The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes. 
  • The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2. 
  • Tight linkage of creatine kinase (CKMM) to myotonic dystrophy on chromosome 19. 
  • Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia. 
  • Unc-13 homolog D mediates an antiviral effect of the chromosome 19 microRNA cluster miR-517a. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology