Chromosomes, Human, Pair 20

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  Subject Areas on Research

  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A three allele TaqI polymorphism at TOP1 gene. 
  • Analysis of the prostate cancer-susceptibility locus HPC20 in 172 families affected by prostate cancer. 
  • Chromosomes with high gene density are preferentially repaired in human cells. 
  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. 
  • Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis. 
  • Expression and regulation of alpha 1-adrenergic receptors in human tissues. 
  • Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci. 
  • Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes. 
  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. 
  • Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency. 
  • Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. 
  • Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. 
  • Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. 
  • Support of linkage of Gerstmann-Sträussler-Scheinker syndrome to the prion protein gene on chromosome 20p12-pter. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. 
  • Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs.