Chromosomes, Human, Pair 6

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  Subject Areas on Research

  • A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. 
  • A physical map of the mouse genome. 
  • A second-generation genomic screen for multiple sclerosis. 
  • Age at onset in two common neurodegenerative diseases is genetically controlled. 
  • Allelic loss on chromosome 6Q in primary prostate cancer. 
  • Characterization of frequently deleted 6q locus in prostate cancer. 
  • Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease. 
  • Chronic lymphocytic leukemia with t(6;14) (p21;q32) CCND3-IGH: CCND3 rearrangement does not necessarily define a cyclin D1-negative mantle cell lymphoma. 
  • Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations. 
  • Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes. 
  • Complete genomic screen in Parkinson disease: evidence for multiple genes. 
  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. 
  • DEK oncogene expression during normal hematopoiesis and in Acute Myeloid Leukemia (AML). 
  • European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry. 
  • Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure. 
  • Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids. 
  • Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. 
  • Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. 
  • Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. 
  • Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. 
  • Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. 
  • Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population. 
  • Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project. 
  • Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients. 
  • Haplotype-based analysis: a summary of GAW16 Group 4 analysis. 
  • Hypereosinophilic syndrome and hemimelia in a patient with chromosome 6p22.3 deletion. 
  • Identification and characterization of proximal 6q deletions in prostate cancer. 
  • Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. 
  • Linkage of familial dilated cardiomyopathy with conduction defect and muscular dystrophy to chromosome 6q23. 
  • Melanoma proliferation and chemoresistance controlled by the DEK oncogene. 
  • Minors come of age: Minor histocompatibility antigens and graft-versus-host disease. 
  • Multiple susceptibility loci for multiple sclerosis. 
  • Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. 
  • North Carolina macular dystrophy (MCDR1) locus: a fine resolution genetic map and haplotype analysis. 
  • North Carolina macular dystrophy is assigned to chromosome 6. 
  • Novel retrotransposed imprinted locus identified at human 6p25. 
  • Prognostic relevance of 6q deletion in Waldenström's macroglobulinemia: a multicenter study. 
  • Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration. 
  • Subtelomeric deletions of chromosome 6p: molecular and cytogenetic characterization of three new cases with phenotypic overlap with Ritscher-Schinzel (3C) syndrome. 
  • T (brachyury) gene duplication confers major susceptibility to familial chordoma. 
  • The DEK protein--an abundant and ubiquitous constituent of mammalian chromatin. 
  • The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. 
  • The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. 
  • Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity. 
  • Uveal melanocytomas: genetic comparison with uveal and dermal melanomas. 
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  Keywords of People

  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology