Chromosomes, Human, Pair 7

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  Subject Areas on Research

  • A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. 
  • A fully automated artificial intelligence method for non-invasive, imaging-based identification of genetic alterations in glioblastomas. 
  • A locus for cerebral cavernous malformations maps to chromosome 7q in two families. 
  • A novel chromosomal rearrangement associated with therapy-related acute leukemia. 
  • A patient with duplication (7)(p22.1pter) characterized by array-CGH. 
  • Adjusting for covariates on a slippery slope: linkage analysis of change over time. 
  • Allelotype analysis of uterine leiomyoma: localization of a potential tumor suppressor gene to a 4-cM region of chromosome 7q. 
  • Analysis of the RELN gene as a genetic risk factor for autism. 
  • Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization. 
  • Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis. 
  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. 
  • Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. 
  • Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma. 
  • Confirmation of a second locus for CMT2 and evidence for additional genetic heterogeneity. 
  • Correlation between selected environmental exposures and karyotype in acute myelocytic leukemia. 
  • Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). 
  • De novo partial duplication of chromosome 7p in a male with autistic disorder. 
  • Discovering sequences with potential regulatory characteristics. 
  • Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma. 
  • Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma. 
  • Evidence for multiple loci from a genome scan of autism kindreds. 
  • Familial chordoma, a tumor of notochordal remnants, is linked to chromosome 7q33. 
  • Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. 
  • Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch. 
  • Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes. 
  • Genetic studies of autistic disorder and chromosome 7. 
  • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 
  • Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. 
  • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. 
  • High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. 
  • High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35. 
  • Identification of a new autosomal dominant limb-girdle muscular dystrophy locus on chromosome 7. 
  • Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins. 
  • Identification of novel genes in late-onset Alzheimer's disease. 
  • Malignant giant cell tumor of synovium (malignant pigmented villonodular synovitis). 
  • Mild cystic fibrosis in a consanguineous family. 
  • Mild cystic fibrosis linked to chromosome 7q22 markers with an uncommon haplotype. 
  • Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms. 
  • Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome. 
  • Multiple susceptibility loci for multiple sclerosis. 
  • Mutations in the TSGA14 gene in families with autism spectrum disorders. 
  • Myeloid neoplasms secondary to plasma cell myeloma: an intrinsic predisposition or therapy-related phenomenon? A clinicopathologic study of 41 cases and correlation of cytogenetic features with treatment regimens. 
  • No association between the WNT2 gene and autistic disorder. 
  • Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome. 
  • Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. 
  • Pallister-Hall syndrome associated with an unbalanced chromosome translocation. 
  • Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases. 
  • Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig. 
  • Refinement of 2q and 7p loci in a large multiplex NTD family. 
  • Relationship between gene amplification and chromosomal deviations in malignant human gliomas. 
  • Replication of the recessive STBMS1 locus but with dominant inheritance. 
  • Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 
  • Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes. 
  • T-lymphoblastic lymphoma and acute myeloid leukaemia transformed from myeloid neoplasm with eosinophilia: a divergent evolution of myeloid neoplasm with monosomy 7 but no detectable tyrosine kinase gene rearrangements designated by the WHO Classification. 
  • The Prader-Willi/Angelman imprinted domain and its control center. 
  • The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system. 
  • Utility of EGFR and PTEN numerical aberrations in the evaluation of diffusely infiltrating astrocytomas. Laboratory investigation. 
  • Whole genomewide linkage screen for neural tube defects reveals regions of interest on chromosomes 7 and 10. 
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  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology