Chromosomes, Human, Pair 8
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Subject Areas on Research
- A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation.
- A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
- A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19.
- A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.
- A subtle t(3;8) results in plausible juxtaposition of MYC and BCL6 in a child with Burkitt lymphoma/leukemia and ataxia-telangiectasia.
- Adult patients with de novo acute myeloid leukemia and t(9; 11)(p22; q23) have a superior outcome to patients with other translocations involving band 11q23: a cancer and leukemia group B study.
- Allelic loss on chromosome arm 8p: analysis of sporadic epithelial ovarian tumors.
- Allelotype of endometrial carcinoma.
- An integrated physical map of 8q22-q24: use in positional cloning and deletion analysis of Langer-Giedion syndrome.
- Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.
- Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.
- Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations.
- Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1.
- Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization.
- Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population.
- Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
- Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma.
- Complete genomic screen in Parkinson disease: evidence for multiple genes.
- Detecting structure of haplotypes and local ancestry.
- Expression and regulation of alpha 1-adrenergic receptors in human tissues.
- Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22): results from Cancer and Leukemia Group B 8461.
- Fine localization of the CMT4A locus using a PAC contig and haplotype analysis.
- Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia.
- GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.
- Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21.
- Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
- Genome-wide linkage scan for primary open angle glaucoma: influences of ancestry and age at diagnosis.
- Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.
- Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8.
- Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.
- Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.
- Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.
- Linkage of 'pure' autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity.
- Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q.
- Loss of chromosome 8p sequences in human breast carcinoma cell lines.
- Malignant rhabdoid tumor of the kidney: involvement of chromosome 22.
- Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered.
- Physical and genetic mapping of the CMT4A locus and exclusion of PMP-2 as the defect in CMT4A.
- Proliferation indices correlate with diagnosis and metastasis in diagnostically challenging melanocytic tumors.
- Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report.
- Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study.
- Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22.
- Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level.
- Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
- Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8.
- Trisomy 8 mosaicism: selective growth advantage of normal cells vs. growth disadvantage of trisomy 8 cells.
- Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer.
- Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review.
- [Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population].
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Keywords of People
- Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics