Chromosomes, Human, Pair 8
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Subject Areas on Research
- A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation.
- A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
- A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19.
- A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.
- A subtle t(3;8) results in plausible juxtaposition of MYC and BCL6 in a child with Burkitt lymphoma/leukemia and ataxia-telangiectasia.
- Allelic loss on chromosome arm 8p: analysis of sporadic epithelial ovarian tumors.
- An integrated physical map of 8q22-q24: use in positional cloning and deletion analysis of Langer-Giedion syndrome.
- Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.
- Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations.
- Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1.
- Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization.
- Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
- Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma.
- Complete genomic screen in Parkinson disease: evidence for multiple genes.
- Deletion of cyclin-dependent kinase 4 inhibitor genes P15 and P16 in non-Hodgkin's lymphoma.
- Expression and regulation of alpha 1-adrenergic receptors in human tissues.
- Familial spastic paraplegia: clinical observations and genetic studies.
- Fine localization of the CMT4A locus using a PAC contig and haplotype analysis.
- Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia.
- Gain of chromosome 8q is associated with metastases and poor survival of patients with clear cell renal cell carcinoma.
- Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21.
- Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
- Genome-wide linkage scan for primary open angle glaucoma: influences of ancestry and age at diagnosis.
- Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8.
- Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.
- Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.
- Linkage of 'pure' autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity.
- Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q.
- Malignant rhabdoid tumor of the kidney: involvement of chromosome 22.
- Physical and genetic mapping of the CMT4A locus and exclusion of PMP-2 as the defect in CMT4A.
- Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report.
- Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study.
- Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22.
- SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant.
- Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer.
- Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics