Cilia
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Subject Areas on Research
- A Mec17-Myosin II Effector Axis Coordinates Microtubule Acetylation and Actin Dynamics to Control Primary Cilium Biogenesis.
- A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination.
- A novel role for primary cilia in airway remodeling.
- A proteomic analysis of human cilia: identification of novel components.
- A3 adenosine and CB1 receptors activate a PKC-sensitive Cl- current in human nonpigmented ciliary epithelial cells via a G beta gamma-coupled MAPK signaling pathway.
- Activation by odorants of a multistate cation channel from olfactory cilia.
- Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia.
- Axonal Odorant Receptors Mediate Axon Targeting.
- Beta-arrestin-mediated localization of smoothened to the primary cilium.
- Broken detailed balance at mesoscopic scales in active biological systems.
- Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
- Ciliated epithelial cell lifespan in the mouse trachea and lung.
- Conditional stabilization of beta-catenin expands the pool of lung stem cells.
- Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin.
- Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases.
- Discordant organ laterality in monozygotic twins with primary ciliary dyskinesia.
- Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.
- Flagellar motility requires the cAMP-dependent phosphorylation of a heat-stable NP-40-soluble 56 kd protein, axokinin.
- Gene expression and larval evolution: changing roles of distal-less and orthodenticle in echinoderm larvae.
- Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling.
- Hedgehog signaling requires motile cilia in the sea urchin.
- IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells.
- Integrin-β1 is required for the renal cystogenesis caused by ciliary defects.
- Intracellular and extracellular forces drive primary cilia movement.
- Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking.
- Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration.
- Lung development and repair: contribution of the ciliated lineage.
- Mucin is produced by clara cells in the proximal airways of antigen-challenged mice.
- Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.
- Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome.
- Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins.
- PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia.
- Parent stem cells can serve as niches for their daughter cells.
- Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release.
- Presence and indirect immunofluorescent localization of calmodulin in Paramecium tetraurelia.
- Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity.
- Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes.
- Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl.
- RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia.
- Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.
- Scanning electron microscopic study of the airways in normal children and in patients with cystic fibrosis and other lung diseases.
- Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli.
- Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base.
- Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.
- TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
- TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells.
- The actin nucleator Cordon-bleu is required for development of motile cilia in zebrafish.
- The prevalence of abnormal cilia in normal pediatric lungs.
- The primary cilium as a Hedgehog signal transduction machine.
- The primary cilium: a signalling centre during vertebrate development.
- The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
- Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus.
- ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute