Circadian Rhythm

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  Subject Areas on Research

  • "Speed" warps time: methamphetamine's interactive roles in drug abuse, habit formation, and the biological clocks of circadian and interval timing. 
  • 24-hour ambulatory blood pressure monitoring. 
  • A Flick of the Tail Keeps the Circadian Clock in Line. 
  • A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period. 
  • A comparison of activity patterns for captive Propithecus tattersalli and Propithecus coquereli. 
  • A day-centered approach to modeling cortisol: diurnal cortisol profiles and their associations among U.S. adults. 
  • A focal cryogenic brain lesion does not reduce the minimum alveolar concentration for halothane in rats. 
  • A murine model of hyperdopaminergic state displays altered respiratory control. 
  • A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding. 
  • A scleral buckle pressure gauge for continuous monitoring of intraocular pressure. 
  • AMBULATORY BLOOD PRESSURE PATTERNS IN PATIENTS WITH RETINAL VEIN OCCLUSION. 
  • Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor. 
  • Activity patterns in seven captive lemur species: Evidence of cathemerality in Varecia and Lemur catta? 
  • Actual and potential transpiration and carbon assimilation in an irrigated poplar plantation. 
  • Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver. 
  • Adolescent Chronotype and Self-Regulation: The Power of When. 
  • Adolescents at clinical-high risk for psychosis: Circadian rhythm disturbances predict worsened prognosis at 1-year follow-up. 
  • Aerobic fitness, acute exercise and sleep in older men. 
  • After hours keeps clock researchers CRYing Overtime. 
  • Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome. 
  • Ambulatory polysomnography: technical aspects and normative values. 
  • An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. 
  • An open trial of morning light therapy for treatment of antepartum depression. 
  • An opposite role for tau in circadian rhythms revealed by mathematical modeling. 
  • Analysis of Genetic and Non-Genetic Factors Influencing Timing and Time Perception. 
  • Anthropoid origins. 
  • Assessing the Importance of IOP Variables in Glaucoma Using a Modified Delphi Process. 
  • Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension. 
  • Associations of Blood Pressure Dipping Patterns With Left Ventricular Mass and Left Ventricular Hypertrophy in Blacks: The Jackson Heart Study. 
  • Autonomic and behavioral responses of selectively bred hypercholinergic rats to oxotremorine and diisopropyl fluorophosphate. 
  • Basal, pulsatile, entropic (patterned), and spiky (staccato-like) properties of ACTH secretion: impact of age, gender, and body mass index. 
  • Beyond intuitive modeling: combining biophysical models with innovative experiments to move the circadian clock field forward. 
  • Binge eating disorder and night eating syndrome: psychological and behavioral characteristics. 
  • Biological clocks and the coordination theory of RNA operons and regulons. 
  • Bladder diary measurements in asymptomatic males: frequency, volume per void, and 24-hr volume. 
  • Blunted nighttime blood pressure dipping in postmenopausal women. 
  • Body temperature and thermal environment in a generalized arboreal anthropoid, wild mantled howling monkeys (Alouatta palliata). 
  • Casein kinase 1: Complexity in the family. 
  • Casein kinase I: another cog in the circadian clockworks. 
  • Casein kinase I: from obscurity to center stage. 
  • Cell cycle oscillators. Temperature compensation of the circadian rhythm of cell division in Euglena. 
  • Cerebrospinal fluid Aβ and tau level fluctuation in an older clinical cohort. 
  • Childhood trauma and diurnal cortisol disruption in fibromyalgia syndrome. 
  • Chronopharmacology of strychnine and allylglycine in the mouse. 
  • Chronotype variation drives night-time sentinel-like behaviour in hunter-gatherers. 
  • Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific. 
  • Circadian disruption--a new direction for psycho-oncology research? A comment on Dedert et al. 
  • Circadian hormone secretory profiles in women with severe premenstrual tension syndrome. 
  • Circadian rhythm and sudden death in heart failure: results from Prospective Randomized Amlodipine Survival Trial. 
  • Circadian rhythm in larval release by the crab Rhithropanopeus harrisii: entrainment model. 
  • Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man. 
  • Circadian rhythms for calcium, inorganic phosphorus, and parathyroid hormone in primary hyperparathyroidism: functional and practical considerations. 
  • Circadian rhythms in Neurospora: a new measurement, the reset zone. 
  • Circadian rhythms in rat mid-brain and caudate nucleus biogenic amine levels. 
  • Circadian rhythms in simulated and manned orbital space flight. 
  • Circadian variation in ischemic stroke subtypes. 
  • Circumstances influencing Otto Loewi's discovery of chemical transmission in the nervous system. 
  • Clinical associations of 11-hydroxycorticosteroid suppression and non-suppression in severe depressive illnesses. 
  • Clopidogrel does not induce fibrinolysis in healthy subjects. 
  • Combined organizational and activational effects of short and long photoperiods on spatial and temporal memory in rats. 
  • Comparing office-based and ambulatory blood pressure monitoring in clinical trials. 
  • Comparison of brainstem and adrenal circadian patterns of epinephrine synthesis. 
  • Cone outer segments: a biophysical model of membrane dynamics, shape retention, and lamella formation. 
  • Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. 
  • Corticosteroids in brain tissue. 
  • Corticotropin secretory dynamics in humans under low glucocorticoid feedback. 
  • Cortisol levels and responses to mammography screening in breast cancer survivors: a pilot study. 
  • Coupling diurnal cytosolic Ca2+ oscillations to the CAS-IP3 pathway in Arabidopsis. 
  • Daily activities and sleep quality in college students. 
  • Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. 
  • Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women. 
  • Diagnosing night sweats requires clear definition. 
  • Diagnosing night sweats. 
  • Diagnostic significance of vegetative symptoms in depression. 
  • Differences in night-time and daytime ambulatory blood pressure when diurnal periods are defined by self-report, fixed-times, and actigraphy: Improving the Detection of Hypertension study. 
  • Differential Sensitivity to Ethanol-Induced Circadian Rhythm Disruption in Adolescent and Adult Mice. 
  • Differential responses to changes in growth temperature between trees from different functional groups and biomes: a review and synthesis of data. 
  • Diurnal and seasonal variation in root xylem embolism in neotropical savanna woody species: impact on stomatal control of plant water status. 
  • Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an ON-type bipolar cell terminal. 
  • Diurnal variation in intraocular pressure. 
  • Diurnal variation in retinal thickening measurement by optical coherence tomography in center-involved diabetic macular edema. 
  • Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis. 
  • Diurnal variations in articular cartilage thickness and strain in the human knee. 
  • Diurnal variations in incidence and outcome of out-of-hospital cardiac arrest including prior comorbidity and pharmacotherapy: a nationwide study in Denmark. 
  • Diurnal variations in the toxicity and tissue levels of spermidine in mice. 
  • Dynamic, but not static, pain sensitivity predicts exercise-induced muscle pain: covariation of temporal sensory summation and pain intensity. 
  • Effect of MR imaging on the normal human pineal body: measurement of plasma melatonin levels. 
  • Effect of dietary patterns on ambulatory blood pressure : results from the Dietary Approaches to Stop Hypertension (DASH) Trial. DASH Collaborative Research Group. 
  • Effect of photoperiod reversal on twenty-four hour patterns for GABA levels in rat brain. 
  • Effect of photoperiod reversal on twenty-four hour patterns for dopamine levels in the corpus striatum and upper and lower brainstem of the rat. 
  • Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats. 
  • Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial. 
  • Effects of perceived racism and anger inhibition on ambulatory blood pressure in African Americans. 
  • Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat. 
  • Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons. 
  • Endocrine control of psychomotor activity in the rat: effects of chronic dexamethasone upon general activity. 
  • Endothelial function in postmenopausal women with nighttime systolic hypertension. 
  • Entrainment of the Circadian Rhythm in Egg Hatching of the Crab Dyspanopeus sayi by Chemical Cues from Ovigerous Females. 
  • Estimating between- and within-individual variation in cortisol levels using multilevel models. 
  • Ethnic differences in left ventricular structure: relations to hemodynamics and diurnal blood pressure variation. 
  • Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure. 
  • Eveningness and Later Sleep Timing Are Associated with Greater Risk for Alcohol and Marijuana Use in Adolescence: Initial Findings from the National Consortium on Alcohol and Neurodevelopment in Adolescence Study. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans. 
  • Fertilization effects on mean stomatal conductance are mediated through changes in the hydraulic attributes of mature Norway spruce trees. 
  • Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes. 
  • Geographic Variation of Plant Circadian Clock Function in Natural and Agricultural Settings. 
  • Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock. 
  • HPA axis function in male caregivers: effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR). 
  • Habitat and behaviour of yellowfin tuna Thunnus albacares in the Gulf of Mexico determined using pop-up satellite archival tags. 
  • Hadza sleep biology: Evidence for flexible sleep-wake patterns in hunter-gatherers. 
  • Hemlock woolly adelgid (Adelges tsugae) infestation affects water and carbon relations of eastern hemlock (Tsuga canadensis) and Carolina hemlock (Tsuga caroliniana). 
  • High body mass index is associated with increased diurnal strains in the articular cartilage of the knee. 
  • Home assessment of diurnal intraocular pressure in healthy children using the Icare rebound tonometer. 
  • Home tonometry for management of pediatric glaucoma. 
  • Hope, pride, and processing during optimal and nonoptimal times of day. 
  • Hostility is related to blunted beta-adrenergic receptor responsiveness among middle-aged women. 
  • How the circadian rhythm affects sleep, wakefulness, and overall health: background for understanding shift work disorder. 
  • Hydraulic redistribution in a Douglas-fir forest: lessons from system manipulations. 
  • Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls. 
  • Icare ONE Home Tonometry in Children With and Without Known Glaucoma. 
  • Identification of inhibitory autophosphorylation sites in casein kinase I epsilon. 
  • Impaired growth hormone secretion in the adult population: relation to age and adiposity. 
  • In response to "is non-dipping status related to coronary heart disease in postmenopausal women?". 
  • In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients. 
  • Individual differences in the day-to-day variability of pain, fatigue, and well-being in patients with rheumatic disease: associations with psychological variables. 
  • Interactions between sleep and epilepsy. 
  • Keeping the beat in the rising heat. 
  • Laboratory-based blood pressure recovery is a predictor of ambulatory blood pressure. 
  • Larval release rhythm of the mole crab Emerita talpoida (Say). 
  • Leptin levels and luteinizing hormone pulsatility in normal cycling women and their relationship to daily changes in metabolic rate. 
  • Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania. 
  • Low heart rate variability and the effect of depression on post-myocardial infarction mortality. 
  • MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells. 
  • Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study. 
  • Maternal cortisol disproportionately impacts fetal growth in male offspring: evidence from the Philippines. 
  • Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist. 
  • Melatonin: a chemical photoperiodic signal with clinical significance in humans. 
  • Menstrual cycle-dependent variations of breast cyst fluid proteins and sex steroid receptors in the normal human breast. 
  • Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia. 
  • Mood variability in adolescents: a study of depressed, nondepressed and comorbid patients. 
  • Morning Versus Evening Bright Light Treatment at Home to Improve Function and Pain Sensitivity for Women with Fibromyalgia: A Pilot Study. 
  • Morningness-eveningness and risk taking. 
  • Motivated behavior and the estrous cycle in rats. 
  • Mouse model of Timothy syndrome recapitulates triad of autistic traits. 
  • Neuroendocrine regulation in depression. I. Limbic system-adrenocortical dysfunction. 
  • Neuroendocrinology of melatonin in reproduction: recent developments. 
  • Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development. 
  • Neurotransmitter studies of neuroendocrine pathology in depression. 
  • Neurovegetative symptoms in chronic pain and depression. 
  • Night and day: the comparative study of strepsirrhine primates reveals socioecological and phylogenetic patterns in olfactory signals. 
  • Nighttime blood pressure dipping in postmenopausal women with coronary heart disease. 
  • Nighttime blood pressure dipping in young adults and coronary artery calcium 10-15 years later: the coronary artery risk development in young adults study. 
  • Nighttime blood pressure dipping: the role of the sympathetic nervous system. 
  • Nocturnal ACTH, cortisol, growth hormone, and prolactin secretion in prepubertal depression. 
  • Nocturnal and early morning secretion of ACTH and cortisol in humans. 
  • Nocturnal blood pressure non-dipping, posttraumatic stress disorder, and sleep quality in women. 
  • Nocturnal patterns of heart rate and the risk of mortality after acute myocardial infarction. 
  • Nocturnal polyuria in women with overactive bladder symptoms and nocturia. 
  • Normative bladder diary measurements: night versus day. 
  • Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. 
  • Olfactory fossa of Tremacebus harringtoni (platyrrhini, early Miocene, Sacanana, Argentina): implications for activity pattern. 
  • Opsin, G-protein and 48-kDa protein in normal and rd mouse retinas: developmental expression of mRNAs and proteins and light/dark cycling of mRNAs. 
  • Optical coherence tomography measurements and analysis methods in optical coherence tomography studies of diabetic macular edema. 
  • Oxidative DNA damage during night shift work. 
  • Oxidative DNA damage during sleep periods among nightshift workers. 
  • PIIANP and HELIXII diurnal variation. 
  • Pathophysiology of hypercortisolism in depression. 
  • Paying attention to time as one gets older. 
  • Phosphorylation and destabilization of human period I clock protein by human casein kinase I epsilon. 
  • Phototaxis by the dinoflagellate Gymnodinium splendens Lebour. 
  • Physiologic circadian rhythmicity in preterm infants. 
  • Positive affect is associated with cardiovascular reactivity, norepinephrine level, and morning rise in salivary cortisol. 
  • Post-translational modifications regulate the ticking of the circadian clock. 
  • Preterm infants born at less than 31 weeks' gestation have improved growth in cycled light compared with continuous near darkness. 
  • Protein phosphatase 1 regulates the stability of the circadian protein PER2. 
  • Protein serine/threonine phosphatases: life, death, and sleeping. 
  • Proximate control of diel vertical migration in Phyllosoma larvae of the Caribbean spiny lobster Panulirus argus. 
  • Racial differences in abnormal ambulatory blood pressure monitoring measures: Results from the Coronary Artery Risk Development in Young Adults (CARDIA) study. 
  • Racial differences in nocturnal dipping status in diabetic kidney disease: Results from the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) study. 
  • Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings. 
  • Rat brain amines, blood histamine and glucose levels in relationship to circadian changes in sleep induced by pentobarbitone sodium. 
  • Redox rhythm reinforces the circadian clock to gate immune response. 
  • Relationship between transferrin saturation and iron stores in the African American and US Caucasian populations: analysis of data from the third National Health and Nutrition Examination Survey. 
  • Religiosity may help preserve the cortisol rhythm in women with stress-related illness. 
  • Renal responses during a dry saturation dive to 450 msw. 
  • Reply: circadian variations of ventricular arrhythmias and sleep-disordered breathing in HF patients. 
  • Resistance to suppression by dexamethasone of plasma 11-O.H.C.S. levels in severe depressive illness. 
  • Retinomotor movements in isolated teleost retinal cone inner-outer segment preparations (CIS-COS): effects of light, dark and dopamine. 
  • Reversible protein phosphorylation regulates circadian rhythms. 
  • Rhythmicity and response to A.M. and P.M. CRH challenge in elderly subjects. 
  • Rice yields in tropical/subtropical Asia exhibit large but opposing sensitivities to minimum and maximum temperatures. 
  • Risk of napping: excessive daytime sleepiness and mortality in an older community population. 
  • SW1PerS: Sliding windows and 1-persistence scoring; discovering periodicity in gene expression time series data. 
  • Salivary estradiol and testosterone in Filipino men: Diurnal patterns and relationships with adiposity. 
  • Seasonal and circadian variations of acute myocardial infarction: Findings from the Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) program. 
  • Seasonality, sociality, and reproduction: Long-term stressors of ring-tailed lemurs (Lemur catta). 
  • Self-reported diurnal mood changes, early morning awakening and the dexamethasone suppression test in endogenous depression. 
  • Serum complement and immunity in experimental simian malaria. I. Cyclical alterations in C4 related to schizont rupture. 
  • Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. 
  • Social jetlag, obesity and metabolic disorder: investigation in a cohort study. 
  • Sources of variability in repeated T-helper lymphocyte counts from human immunodeficiency virus type 1-infected patients: total lymphocyte count fluctuations and diurnal cycle are important. 
  • Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid. 
  • Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease. 
  • Stress, cortisol, and externalizing behavior in adolescent males: an examination in the context of multisystemic therapy. 
  • Structural adjustments in resprouting trees drive differences in post-fire transpiration. 
  • Surgical treatment of carpal tunnel syndrome in patients with peripheral neuropathy. 
  • Sustained attention performance during sleep deprivation associates with instability in behavior and physiologic measures at baseline. 
  • Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. 
  • Systems approaches to identifying gene regulatory networks in plants. 
  • Temporal differences in out-of-hospital cardiac arrest incidence and survival. 
  • Temporal organization of sleep-wake states in preterm infants. 
  • The 'internal clocks' of circadian and interval timing. 
  • The 'internal clocks' of circadian and interval timing. 
  • The DASH diet enhances the blood pressure response to losartan in hypertensive patients. 
  • The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth. 
  • The Local Edge Machine: inference of dynamic models of gene regulation. 
  • The acute toxicity of drugs acting at cholinoceptive sites and twenty-four hour rhythms in brain acetylcholine. 
  • The dexamethasone suppression test: an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in Psychiatry. 
  • The effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure. 
  • The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged. 
  • The efficacy of the appetite suppressant, diethylpropion, is dependent on both when it is given (day vs. night) and under conditions of high fat dietary restriction. 
  • The influence of drug ,reatment on norepinephrine levels and ultrastructure of the rat hypothalamus and caudate nucleus during a programmed light-dark cycle. 
  • The temporal spectrum of adult mosquito population fluctuations: conceptual and modeling implications. 
  • Therapy of circadian rhythm disorders in chronic fatigue syndrome: no symptomatic improvement with melatonin or phototherapy. 
  • Time of day affects episodic memory in older adults. 
  • Timing Is Everything. 
  • Timing for the Introduction of Cycled Light for Extremely Preterm Infants: A Randomized Controlled Trial. 
  • Timing of plant immune responses by a central circadian regulator. 
  • Towards an integrated understanding of the biology of timing. 
  • Transpiration-induced axial and radial tension gradients in trunks of Douglas-fir trees. 
  • Twenty-four hour rhythms in the glycine content of rat hindbrain and spinal cord. 
  • Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system. 
  • Unexpected deviation in circadian variation of ventricular arrhythmias: the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial). 
  • Urinary vasopressin and aldosterone and plasma volume during a saturation dive to 450 m. 
  • Using daily ratings to confirm premenstrual syndrome/late luteal phase dysphoric disorder. Part II. What makes a "real" difference? 
  • Variation in osteoarthritis biomarkers from activity not food consumption. 
  • Variations in levels of blood pressure: of prognostic value or not? 
  • Voluntary wheel running initially increases adrenal sensitivity to adrenocorticotrophic hormone, which is attenuated with long-term training. 
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  Keywords of People

  • Dedert, Eric, Assistant Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Williams, Blythe A., Associate Professor of the Practice in the Department of Evolutionary Anthropology, Evolutionary Anthropology