Citric Acid Cycle

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  Subject Areas on Research

  • 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). 
  • A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation. 
  • Altered metabolism in cancer. 
  • Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells. 
  • Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae. 
  • Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE. 
  • Computational approaches for understanding energy metabolism. 
  • Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. 
  • Epigenetics and cancer metabolism. 
  • Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity. 
  • Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa). 
  • IDH3α regulates one-carbon metabolism in glioblastoma. 
  • Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism. 
  • Mechanism of action of a respiratory inhibitor from the gill tissue of the sporulating common mushroom, Agaricus bisporus. 
  • Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment. 
  • Metabolomics applied to diabetes research: moving from information to knowledge. 
  • Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies. 
  • Novel therapeutic targets of tumor metabolism. 
  • Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. 
  • Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. 
  • Pathogenesis of A⁻β⁺ ketosis-prone diabetes. 
  • Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis. 
  • Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men. 
  • Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine. 
  • Quantitative Analysis of the Physiological Contributions of Glucose to the TCA Cycle. 
  • Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection. 
  • Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion. 
  • Rewiring of glycolysis in cancer cell metabolism. 
  • Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism. 
  • Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism. 
  • Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney. 
  • The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer. 
  • The intestine is a major contributor to circulating succinate in mice. 
  • The therapeutic implications of immunosuppressive tumor aerobic glycolysis. 
  • Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease.