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Subject Areas on Research
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14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1.
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440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.
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A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis.
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A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins.
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A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.
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A Fringe-modified Notch signal affects specification of mesoderm and endoderm in the sea urchin embryo.
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A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.
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A beta-spectrin isoform from Drosophila (beta H) is similar in size to vertebrate dystrophin.
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A candidate taste receptor gene near a sweet taste locus.
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A cell surface receptor mediates extracellular Ca(2+) sensing in guard cells.
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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
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A cloned calmodulin structural gene probe is complementary to DNA sequences from diverse species.
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A compensatory base change in human U2 snRNA can suppress a branch site mutation.
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A comprehensive panel of near-full-length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1.
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A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.
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A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria.
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A feedback loop in the polo-like kinase activation pathway.
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A functional analysis of the spacer of V(D)J recombination signal sequences.
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A gene hunting we will go!
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A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.
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A genetic screen reveals Arabidopsis stomatal and/or apoplastic defenses against Pseudomonas syringae pv. tomato DC3000.
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A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function.
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A high proportion of ADA point mutations associated with a specific alanine-to-valine substitution.
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A highly sensitive and specific enzyme-linked immunosorbent assay of antibodies to hepatitis C virus.
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A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen.
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A human protein related to yeast Cdc6p.
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A magnificent time with the "magnificent seven" transmembrane spanning receptors.
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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.
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A member of a family of sulfate-activating enzymes causes murine brachymorphism.
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A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer.
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A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium.
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A mouse homoeo box gene is expressed during embryogenesis and in adult kidney.
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A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.
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A mouse model of familial porphyria cutanea tarda.
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A multigene family encoding a diverse array of putative pheromone receptors in mammals.
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A multimember kinesin gene family in Drosophila.
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A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation.
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A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.
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A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene.
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A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate.
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A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC.
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A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.
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A novel polypeptide secreted by activated human T lymphocytes.
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A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning.
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A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis.
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A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.
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A physical map of the human genome.
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A physical map of the mouse genome.
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A potentially abundant junctional RNA motif stabilized by m6A and Mg2.
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A poxvirus-derived vector that directs high levels of expression of cloned genes in mammalian cells.
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A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA.
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A public database for gene expression in human cancers.
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A role for rat inositol polyphosphate kinases rIPK2 and rIPK1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells.
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A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion.
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A sea urchin genome project: sequence scan, virtual map, and additional resources.
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A simple formula useful for positional cloning.
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A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis.
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A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells.
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A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.
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A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor.
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A yeast artificial chromosome contig encompassing the type 1 neurofibromatosis gene.
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ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.
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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity.
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Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease.
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Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling.
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Activation of tat-defective human immunodeficiency virus by ultraviolet light.
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Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1.
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Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.
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Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements.
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Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes.
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Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans.
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Aggressive fibromatosis (desmoid tumor) is a monoclonal disorder.
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Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli.
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Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.
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Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing.
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Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
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Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C.
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Amplification and cloning of near full-length HIV-2 genomes.
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An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate.
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An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides.
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An integrated YAC map of the human X chromosome.
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An integrated physical map of 8q22-q24: use in positional cloning and deletion analysis of Langer-Giedion syndrome.
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Analysis of ENU-induced mutations at the Adh locus in Drosophila melanogaster.
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Analysis of autoantibody binding to different regions of the human La antigen expressed in recombinant fusion proteins.
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Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins.
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Analysis of recombinant Phex: an endopeptidase in search of a substrate.
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Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases.
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Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila.
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
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Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA.
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Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.
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Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene.
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AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide.
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Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors.
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Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
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Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers.
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Antiidiotypic antibody recognizes an amiloride binding domain within the alpha subunit of the epithelial Na+ channel.
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Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.
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Arabidopsis cDNA sequence encoding myrosinase.
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Arabidopsis functional genomics.
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Arachidonate and related unsaturated fatty acids selectively inactivate the guanine nucleotide-binding regulatory protein, Gz.
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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.
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Arsenic trioxide uptake by human and rat aquaglyceroporins.
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Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.
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Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'.
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Autoinhibition of casein kinase I epsilon (CKI epsilon) is relieved by protein phosphatases and limited proteolysis.
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BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene.
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Bacterial artificial chromosome cloning and mapping of a 630-kb human extrachromosomal structure.
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Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene.
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Bacterially synthesized vertebrate calmodulin is a specific substrate for ubiquitination.
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Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice.
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Beta-adrenergic receptor kinase: primary structure delineates a multigene family.
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Beta-thalassemia resulting from a single nucleotide substitution in an acceptor splice site.
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Beyond QTL cloning.
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Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases.
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Biochemical and structural insights into bacterial organelle form and biogenesis.
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Biochemical characterization of the multifunctional Ca2+/calmodulin-dependent protein kinase type IV expressed in insect cells.
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Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus.
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Bisulfite sequencing of cloned alleles.
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Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells.
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Brain-specific polyA- transcripts are detected in polyA+ RNA: do complex polyA- brain RNAs really exist?
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Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein.
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CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells.
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CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization.
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CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90.
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COBRA encodes a putative GPI-anchored protein, which is polarly localized and necessary for oriented cell expansion in Arabidopsis.
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CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.
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Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.
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Cadherin-6 expression transiently delineates specific rhombomeres, other neural tube subdivisions, and neural crest subpopulations in mouse embryos.
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Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development.
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Calmodulin activation of target enzymes. Consequences of deletions in the central helix.
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Calspermin is a testis specific calmodulin-binding protein closely related to Ca2+/calmodulin-dependent protein kinases.
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Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.
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Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.
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Cassettes of the f1 intergenic region.
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Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
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Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase.
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Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine.
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Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21.
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Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes.
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Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo.
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Characterization of a new family of protein kinases from Arabidopsis containing phosphoinositide 3/4-kinase and ubiquitin-like domains.
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Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger.
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Characterization of alpha 2-adrenergic receptor subtype-specific antibodies.
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Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor.
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Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe.
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Characterization of human Gadd45, a p53-regulated protein.
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Characterization of human prorenin expressed in mammalian cells from cloned cDNA.
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Characterization of moesin in the sea urchin Lytechinus variegatus: redistribution to the plasma membrane following fertilization is inhibited by cytochalasin B.
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Characterization of the DNase I hypersensitive site 3' of the human beta globin gene domain.
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Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants.
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Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells.
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Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region.
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Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae.
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Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin.
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Characterization of the rat type III hexokinase gene promoter. A functional octamer 1 motif is critical for basal promoter activity.
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Chicken calmodulin genes. A species comparison of cDNA sequences and isolation of a genomic clone.
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Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites.
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Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity.
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Chimeric calmodulin-cardiac troponin C proteins differentially activate calmodulin target enzymes.
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Chromosomal assignment of the murine Gi alpha and Gs alpha genes. Implications for the obese mouse.
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Chromosomal localization of human glutamate receptor genes.
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Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.
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Circular transcripts of the testis-determining gene Sry in adult mouse testis.
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Cloned Erwinia chrysanthemi out genes enable Escherichia coli to selectively secrete a diverse family of heterologous proteins to its milieu.
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Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
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Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes.
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Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase.
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Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.
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Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.
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Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.
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Cloning and characterization of a mammalian prenyl protein-specific protease.
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Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex.
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Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.
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Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase.
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Cloning and characterization of the 5' end (exon 1) of the gene encoding human factor X.
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Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters.
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Cloning and characterization of three new murine genes encoding short homologues of RNase P RNA.
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Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.
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Cloning and characterization of two splice variants of human phosphodiesterase 11A.
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Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth.
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Cloning and developmental expression of the chick type II and type III TGF beta receptors.
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Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
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Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.
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Cloning and expression of a novel, truncated, progesterone receptor.
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Cloning and expression of full-length cDNA encoding human vitamin D receptor.
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Cloning and expression of the yeast plasma membrane ATPase in Escherichia coli.
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Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts.
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Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.
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Cloning and sequence analysis of the human beta 1-adrenergic receptor 5'-flanking promoter region.
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Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling.
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Cloning and structural analysis of the human c-kit gene.
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Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology.
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Cloning genes that encode inducible forms of P-450.
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Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts.
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Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues.
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Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19.
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Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.
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Cloning of an aquaporin homologue present in water channel containing endosomes of toad urinary bladder.
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Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor.
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Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.
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Cloning of human androgen receptor complementary DNA and localization to the X chromosome.
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Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire.
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Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene.
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Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog
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Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors.
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Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin.
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Cloning of the gene encoding Leishmania donovani S-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy.
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Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.
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Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1.
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Cloning of the terminal loop of vaccinia virus DNA.
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Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development.
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Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae.
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Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome.
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Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene.
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Cloning, expression, and cellular localization of a human prenylcysteine lyase.
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Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.
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Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.
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Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase.
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Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi.
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Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.
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Cloning, sequencing, and recombinant expression of the porcine inhibitor of carbonic anhydrase: a novel member of the transferrin family.
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Clusterin: an enigmatic protein recruited by diverse stimuli.
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Comparison of human and Xenopus GATA-2 promoters.
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Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.
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Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.
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Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta.
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Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter.
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Construction and characterization of infectious cDNA clones of enterovirus 71 (EV71).
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Construction and phenotypic characterization of HIV type 1 functional envelope clones of subtypes G and F.
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Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products.
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Construction of a fluorescent biosensor family.
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Contribution of a 28-kilodalton membrane protein to the virulence of Haemophilus influenzae.
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Control of a biomolecular motor-powered nanodevice with an engineered chemical switch.
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Control of morphology and virulence by ADP-ribosylation factors (Arf) in Mucor circinelloides.
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Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.
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Coupling diurnal cytosolic Ca2+ oscillations to the CAS-IP3 pathway in Arabidopsis.
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Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
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Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution.
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Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli.
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Crystal structure of the transcription activator BmrR bound to DNA and a drug.
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Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells.
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Crystallization and preliminary X-ray crystallographic studies of glutaredoxin 2 from Saccharomyces cerevisiae in different oxidation states.
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Crystallization of a Complex Between MYC and Jas Motif.
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Current status and strategies for vaccines against diseases induced by human T-cell lymphotropic retroviruses (HTLV-I, -II, -III).
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Cutting of M13mp7 phage DNA and excision of cloned single-stranded sequences by restriction endonucleases.
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Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis.
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D21S194, a jump clone from D21S16.
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DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
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Decoupling of nucleotide- and microtubule-binding sites in a kinesin mutant.
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Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment.
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Deletion and site-directed mutagenesis of the ATP-binding motif (P-loop) in the bifunctional murine ATP-sulfurylase/adenosine 5'-phosphosulfate kinase enzyme.
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Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation.
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Deletion of the essential gene 24 from the bacteriophage T4 genome.
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Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.
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Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2.
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Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4.
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Desensitization of angiotensin receptor function.
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Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.
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Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity.
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Determination of aromatase cytochrome P450 messenger ribonucleic acid in human breast tissue by competitive polymerase chain reaction amplification.
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Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions.
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Development of a serological test for Haemophilus ducreyi for seroprevalence studies.
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Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.
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Different dimerization activities of alpha and beta thyroid hormone receptor isoforms.
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Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes.
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Differential expression of mitochondrial DNA replication factors in mammalian tissues.
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Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack.
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Differential screening of a subtracted cDNA library: a method to search for genes preferentially expressed in multiple tissues.
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Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2.
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Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs.
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Directed evolution of the surface chemistry of the reporter enzyme beta-glucuronidase.
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Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae.
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Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis.
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Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.
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Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA.
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Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis.
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Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins.
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Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family.
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Drug uptake and pharmacological modulation of drug sensitivity in leukemia by AQP9.
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ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.
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Effector coupling mechanisms of the cloned 5-HT1A receptor.
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Effects of cholecystokinin on pancreatic ornithine decarboxylase gene expression.
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Efficient random subcloning of DNA sheared in a recirculating point-sink flow system.
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Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis.
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Emergence of the keratinocyte growth factor multigene family during the great ape radiation.
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Engineering DNA vaccines via co-delivery of co-stimulatory molecule genes.
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Engineering soluble major histocompatibility molecules: why and how.
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Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase.
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Equalizing cDNA subtraction based on selective suppression of polymerase chain reaction: cloning of Jurkat cell transcripts induced by phytohemaglutinin and phorbol 12-myristate 13-acetate.
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Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95.
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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.
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Erythropoietin structure-function relationships. Mutant proteins that test a model of tertiary structure.
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Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.
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Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme.
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Essential light chain of Drosophila nonmuscle myosin II.
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Evidence for independent recruitment of zeta-crystallin/quinone reductase (CRYZ) as a crystallin in camelids and hystricomorph rodents.
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Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000.
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Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.
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Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes.
-
Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites.
-
Excitatory amino acid receptors and epilepsy.
-
Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency.
-
Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
-
Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.
-
Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region.
-
Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA.
-
Expression cloning and characterization of the TGF-beta type III receptor.
-
Expression cloning of TGF-beta receptors.
-
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.
-
Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases.
-
Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.
-
Expression cloning of type 2 angiotension II receptor reveals a unique class of seven-transmembrane receptors.
-
Expression of SV40 and polyoma T antigens in E. coli.
-
Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).
-
Expression of a functional antizearalenone single-chain Fv antibody in transgenic Arabidopsis plants.
-
Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.
-
Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain.
-
Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer.
-
Expression of cyp26b1 during zebrafish early development.
-
Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions.
-
Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies.
-
Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells.
-
Expression of polyoma early gene products in E. coli.
-
Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae.
-
Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma.
-
Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors.
-
Expression of three alpha 2-adrenergic receptor subtypes in rat tissues: implications for alpha 2 receptor classification.
-
Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans.
-
Extracellular secretion of pectate lyase by the Erwinia chrysanthemi out pathway is dependent upon Sec-mediated export across the inner membrane.
-
Fine mapping of the Pc locus of Sorghum bicolor, a gene controlling the reaction to a fungal pathogen and its host-selective toxin.
-
Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin.
-
FoxP2 expression in avian vocal learners and non-learners.
-
Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. I. In vitro studies.
-
Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes.
-
Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II.
-
Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41.
-
Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression.
-
Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byr1 antibody.
-
Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer.
-
Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs.
-
Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins.
-
Fusions of elastin-like polypeptides to pharmaceutical proteins.
-
G alpha t/G alpha i1 chimeras used to define structural basis of specific functions of G alpha t.
-
GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors.
-
Gateway-compatible tissue-specific vectors for plant transformation.
-
Gene assembly and combinatorial libraries in S. cerevisiae via reiterative recombination.
-
Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction.
-
Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin.
-
Generation of a polyclonal fab phage display library to the human breast carcinoma cell line BT-20.
-
Generation of full-length cDNA libraries enriched for differentially expressed genes.
-
Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees.
-
Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis.
-
Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.
-
Generation of species cross-reactive aptamers using "toggle" SELEX.
-
Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles.
-
Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein.
-
Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis.
-
Genetic regulation of beta-adrenergic receptors.
-
Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation.
-
Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization.
-
Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5.
-
Genomic cloning of hGSTP1*C, an allelic human Pi class glutathione S-transferase gene variant and functional characterization of its retinoic acid response elements.
-
Genomic organization and cloning of the human homologue of murine Sipa-1.
-
Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome.
-
Genomic organization of rat rDNA.
-
Genomic sequence and expression of a cloned human carbonyl reductase gene with daunorubicin reductase activity.
-
Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF).
-
Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development.
-
Guinea pig and bovine zeta-crystallins have distinct functional characteristics highlighting replacements in otherwise similar structures.
-
Gz, a guanine nucleotide-binding protein with unique biochemical properties.
-
HIV quasispecies and resampling.
-
HIV-1 neutralization by chimeric CD4-CG10 polypeptides fused to human IgG1.
-
HNF-3 beta as a regulator of floor plate development.
-
Haem oxygenase-1 prevents cell death by regulating cellular iron.
-
Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.
-
Hemoglobin switching in sheep. Cloning and characterization of the beta A and beta-like embryonic globin genes from genomic DNA.
-
High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae.
-
High-level expression and single-step purification of leucyl-tRNA synthetase from Escherichia coli.
-
High-level expression of Escherichia coli NADPH-sulfite reductase: requirement for a cloned cysG plasmid to overcome limiting siroheme cofactor.
-
High-level synthesis of biologically active reovirus protein sigma 1 in a mammalian expression vector system.
-
Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA.
-
Homer: a protein that selectively binds metabotropic glutamate receptors.
-
Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2.
-
Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility.
-
Human Gi protein alpha-subunit: deduction of amino acid structure from a cloned cDNA.
-
Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression.
-
Human T cell receptor gamma delta structure.
-
Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA.
-
Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.
-
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators.
-
Human beta 1- and beta 2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes.
-
Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.
-
Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.
-
Human colonic biota studied by ribosomal DNA sequence analysis.
-
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies.
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
-
Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.
-
Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.
-
Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma.
-
Hypoexpression and epigenetic regulation of candidate tumor suppressor gene CADM-2 in human prostate cancer.
-
Identification and cloning of a negative regulator of systemic acquired resistance, SNI1, through a screen for suppressors of npr1-1
-
Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms.
-
Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes).
-
Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases.
-
Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450.
-
Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans.
-
Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae.
-
Identification and developmental expression of two activin receptors in baboon lung.
-
Identification and localization of a sea urchin Notch homologue: insights into vegetal plate regionalization and Notch receptor regulation.
-
Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 gene.
-
Identification and sequence of the initiation site for rat 45S ribosomal RNA synthesis.
-
Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast.
-
Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.
-
Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system.
-
Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling.
-
Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid.
-
Identification of a new family of protein phosphatase 2A regulatory subunits.
-
Identification of a new mutation in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
-
Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells.
-
Identification of a new variant of PDE1A calmodulin-stimulated cyclic nucleotide phosphodiesterase expressed in mouse sperm.
-
Identification of a novel gene linked to parkin via a bi-directional promoter.
-
Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species.
-
Identification of additional members of human G-protein-coupled receptor kinase multigene family.
-
Identification of an amplified, highly expressed gene in a human glioma.
-
Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene.
-
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
-
Identification of casein kinase I substrates by in vitro expression cloning screening.
-
Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites.
-
Identification of genes expressed in the Xenopus inner ear.
-
Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4.
-
Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.
-
Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA.
-
Identification of novel murine- and human-specific RPGRIP1 splice variants with distinct expression profiles and subcellular localization.
-
Identification of novel steroid-response elements.
-
Identification of putative human T cell receptor delta complementary DNA clones.
-
Identification of residues in alpha-macroglobulins involved in activation of the alpha 2-macroglobulin signaling receptor.
-
Identification of the promoter region of the human betaIGH3 gene.
-
Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets.
-
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
-
Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes.
-
Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases.
-
Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites.
-
Identifying sequence similarities between DNA molecules.
-
Immunization against SIVmne in macaques using multigenic DNA vaccines.
-
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
-
Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit.
-
Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone.
-
Immunotherapy of cancer with dendritic cell-based vaccines.
-
Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display.
-
Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi.
-
Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.
-
In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent.
-
In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists.
-
In vitro selection of aptamers from RNA libraries.
-
In-vivo studies on the cis-acting replication initiator protein of IncFII plasmid NR1.
-
IncFII plasmid incompatibility product and its target are both RNA transcripts.
-
Indiplon is a high-affinity positive allosteric modulator with selectivity for alpha1 subunit-containing GABAA receptors.
-
Induction of Arabidopsis defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene.
-
Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy.
-
Inhibition of an inflammatory response is mediated by a 38-kDa protein of cowpox virus.
-
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function.
-
Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B.
-
Interplay between SCARECROW, GA and LIKE HETEROCHROMATIN PROTEIN 1 in ground tissue patterning in the Arabidopsis root.
-
Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence.
-
Interrogation of individual intratumoral B lymphocytes from lung cancer patients for molecular target discovery.
-
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells.
-
Involvement of two putative alternative sigma factors in stress response of the radioresistant bacterium Deinococcus radiodurans.
-
Isolation and analysis of cDNA clones expressing human lupus La antigen.
-
Isolation and biochemical characterization of LEAP-2, a novel blood peptide expressed in the liver.
-
Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A.
-
Isolation and characterization of a human pro alpha 2(I) collagen gene segment.
-
Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1.
-
Isolation and characterization of cDNA clones encoding pig gastric mucin.
-
Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.
-
Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene.
-
Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid.
-
Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.
-
Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes.
-
Isolation and nucleotide sequence of canine glucose-6-phosphatase mRNA: identification of mutation in puppies with glycogen storage disease type Ia.
-
Isolation and nucleotide sequence of human liver glycogen debranching enzyme mRNA: identification of multiple tissue-specific isoforms.
-
Isolation and structural analysis of the chromosomal gene for chicken calmodulin.
-
Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family.
-
Isolation of a cDNA clone complementary to sequences for a 34-kilodalton protein which is a pp60v-src substrate.
-
Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse.
-
Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies.
-
Isolation of a rat parvalbumin gene and full length cDNA.
-
Isolation of cDNA clones for basal lamina components: type IV procollagen.
-
Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.
-
Isolation of human sequences that replicate autonomously in human cells.
-
Isolation of song-regulated genes in the brain of songbirds.
-
Isolation of the structural gene for calmodulin.
-
Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification.
-
Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator.
-
KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin.
-
Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin.
-
Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.
-
Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani.
-
Knockdown of mouse VCAM-1 by vector-based siRNA.
-
LAB: a new membrane-associated adaptor molecule in B cell activation.
-
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.
-
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
-
Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3.
-
Light-inducible gene regulation with engineered zinc finger proteins.
-
Linkage of kdr-type resistance and the para-homologous sodium channel gene in German cockroaches (Blattella germanica).
-
Lipoprotein biosynthesis: the avian model.
-
Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase.
-
Localization of cloned unique DNA to three different regions of chromosome 19: screen for linkage probes for myotonic dystrophy.
-
Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.
-
MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: implications for extracellular matrix turnover.
-
MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae.
-
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.
-
Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.
-
Mapping individual cosmid DNAs by direct AFM imaging.
-
Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes.
-
Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes.
-
Mechanical and chemical unfolding of a single protein: a comparison.
-
Mechanisms for regulation of calmodulin kinase IIalpha by Ca(2+)/calmodulin and autophosphorylation of threonine 286.
-
Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.
-
Mechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiency.
-
Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin.
-
MegaGate: A toxin-less gateway molecular cloning tool.
-
Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.
-
Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase.
-
Minidose GnRH-2 for "poor responders." Cloning in place of data torturing?
-
Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.
-
Modulation of glutathione peroxidase expression by selenium: effect on human MCF-7 breast cancer cell transfectants expressing a cellular glutathione peroxidase cDNA and doxorubicin-resistant MCF-7 cells.
-
Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ.
-
Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.
-
Molecular analysis of the 60-kDa human Ro ribonucleoprotein.
-
Molecular analysis of the SCARECROW gene in maize reveals a common basis for radial patterning in diverse meristems.
-
Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.
-
Molecular and cellular mechanism of angiotensin II-mediated apoptosis.
-
Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant.
-
Molecular and genetic approaches for the analysis of C. elegans neuronal development.
-
Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.
-
Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine.
-
Molecular basis for paradoxical carriers of adenosine deaminase (ADA) deficiency that show extremely low levels of ADA activity in peripheral blood cells without immunodeficiency.
-
Molecular basis of an inherited retinal defect in Drosophila.
-
Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR.
-
Molecular biology of nuclear autoantigens.
-
Molecular characterization and functional expression of the DSC1 channel.
-
Molecular characterization and localization of the human MAFG gene.
-
Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source.
-
Molecular characterization of TRP1, a gene coding for tryptophan synthetase in the basidiomycete Coprinus cinereus.
-
Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
-
Molecular cloning and characterization of Aspergillus nidulans cyclophilin B.
-
Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.
-
Molecular cloning and characterization of a novel histone deacetylase HDAC10.
-
Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor.
-
Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype.
-
Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.
-
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
-
Molecular cloning and functional expression of a recombinant 72.5 kDa fragment of the 110 kDa regulatory subunit of smooth muscle protein phosphatase 1M.
-
Molecular cloning and nucleotide sequence of a cDNA clone coding for the cell attachment domain in human fibronectin.
-
Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.
-
Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.
-
Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith Strain).
-
Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.
-
Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA.
-
Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver.
-
Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family.
-
Molecular cloning of KS, a novel rat gene expressed exclusively in the kidney.
-
Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel.
-
Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites.
-
Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families.
-
Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
-
Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling.
-
Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.
-
Molecular cloning of acid alpha-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quails.
-
Molecular cloning of aldolases for synthetic applications.
-
Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells.
-
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.
-
Molecular cloning of dimethyl sulfoxide reductase from Rhodobacter sphaeroides.
-
Molecular cloning of human liver sulfite oxidase.
-
Molecular cloning of laminin.
-
Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues.
-
Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish.
-
Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP).
-
Molecular cloning of rat liver sulfite oxidase. Expression of a eukaryotic Mo-pterin-containing enzyme in Escherichia coli.
-
Molecular cloning of sequences from a Drosophila RNA polymerase II locus by P element transposon tagging.
-
Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor.
-
Molecular cloning of the cDNA for androgen-dependent sperm-coating glycoproteins secreted by the rat epididymis.
-
Molecular cloning of the cDNA for ligatin.
-
Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis.
-
Molecular cloning of the first metazoan beta-1,3 glucanase from eggs of the sea urchin Strongylocentrotus purpuratus.
-
Molecular cloning of the gene sequences of a major apoprotein in avian very low density lipoproteins.
-
Molecular cloning of the structural gene for exopolygalacturonate lyase from Erwinia chrysanthemi EC16 and characterization of the enzyme product.
-
Molecular cloning sequence and distribution of rat calspermin, a high affinity calmodulin-binding protein.
-
Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins.
-
Molecular cloning, expression and functional characterization of rabbit anticoagulant vitamin-K-dependent protein S.
-
Molecular cloning, nucleotide sequence, and marker exchange mutagenesis of the exo-poly-alpha-D-galacturonosidase-encoding pehX gene of Erwinia chrysanthemi EC16.
-
Molecular genetics of yeast.
-
Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones.
-
Molecular mechanisms of glutamate receptor clustering at excitatory synapses.
-
Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene.
-
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase.
-
Monitor peptide binding sites are expressed in the rat liver and small intestine.
-
Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis.
-
Mouse small eye results from mutations in a paired-like homeobox-containing gene.
-
Mouse/human chimeric Me1-14 antibody: genomic cloning of the variable region genes, linkage to human constant region genes, expression, and characterization.
-
Mucor circinelloides: Growth, Maintenance, and Genetic Manipulation.
-
Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium.
-
Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD.
-
Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor.
-
Multiple transcription start sites and 5' alternate splicing of murine IL-3 receptor beta-chain transcripts.
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
-
Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
-
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.
-
Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice.
-
Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c.
-
Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease.
-
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.
-
Mutations of the Ki-ras oncogene in endometrial carcinoma.
-
Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila.
-
NMR structural characterization of the CDK inhibitor p19INK4d.
-
NMR structure of AbhN and comparison with AbrBN: FIRST insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins.
-
Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response.
-
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart.
-
Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea.
-
Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli.
-
Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells.
-
Noncatalytic domains of RGS9-1.Gbeta 5L play a decisive role in establishing its substrate specificity.
-
Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences.
-
Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans.
-
Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype.
-
Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert.
-
Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains.
-
Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family.
-
Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli.
-
Oligomeric structure and tissue distribution of ficolins from mouse, pig and human.
-
Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development.
-
Organization of ribosomal DNA in the basidiomycete Thanatephorus praticola.
-
Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene.
-
Out with the old, in with the new? Comparing methods for measuring protein degradation.
-
Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein.
-
Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
-
Overexpression of the apple MpNPR1 gene confers increased disease resistance in Malus x domestica.
-
Ovomucoid intervening sequences specify functional domains and generate protein polymorphism.
-
P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips.
-
PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells.
-
PSORS2 is due to mutations in CARD14.
-
Paralogous VDRs in teleosts:transition of nuclear receptor function
-
Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe.
-
Phage Trojan horses: a conditional expression system for lethal genes.
-
Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning.
-
Phenotypic characterization of transgenic Japanese medaka (Oryzias latipes) that express a red fluorescent protein in hepatocytes.
-
Phenotypic properties of transmitted founder HIV-1.
-
Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3.
-
Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development.
-
Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10).
-
Phylogenetic comparisons implicate sex hormone-binding globulin in "masculinization" of the female spotted hyena (Crocuta crocuta).
-
Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA loci.
-
Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae.
-
Plasmid models for bacteriophage T4 DNA replication: requirements for fork proteins.
-
Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.
-
Porcine CD80: cloning, characterization, and evidence for its role in direct human T-cell activation.
-
Pore region of TRPV3 ion channel is specifically required for heat activation.
-
Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration.
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
-
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.
-
Positive and negative selection LYS5MX gene replacement cassettes for use in Saccharomyces cerevisiae.
-
Positive-selection cloning vehicle useful for overproduction of hybrid proteins.
-
Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.
-
Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines.
-
Preparation and screening of an arrayed human genomic library generated with the P1 cloning system.
-
Primary structure and domain organization of human alpha and beta adducin.
-
Priming and activation of human ovarian and breast cancer-specific CD8+ T cells by polyvalent Listeria monocytogenes-based vaccines.
-
Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate.
-
Prochlorococcus ecotype abundances in the North Atlantic Ocean as revealed by an improved quantitative PCR method.
-
Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains.
-
Properties of the beta 1- and beta 2-adrenergic receptor subtypes revealed by molecular cloning.
-
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.
-
Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka.
-
Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways.
-
Prox 1, a prospero-related homeobox gene expressed during mouse development.
-
Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis.
-
Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli.
-
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.
-
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.
-
Purification, cloning, and expression of a peripheral-type benzodiazepine receptor.
-
Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro.
-
Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
-
RB-mediated tumor suppression of a lung cancer cell line is abrogated by an extract enriched in extracellular matrix.
-
RGS10 is a selective activator of G alpha i GTPase activity.
-
RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha.
-
RNA binding specificity of a Drosophila snRNP protein that shares sequence homology with mammalian U1-A and U2-B" proteins.
-
RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle.
-
RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells.
-
Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies.
-
Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans.
-
Rapid shotgun cloning utilizing the two base recognition endonuclease CviJI.
-
Rat amylin: cloning and tissue-specific expression in pancreatic islets.
-
Rat pancreatic kallikrein mRNA: nucleotide sequence and amino acid sequence of the encoded preproenzyme.
-
Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity.
-
Receptor class desensitization of leukocyte chemoattractant receptors.
-
Recombinant DNA strategies in genetic neurological diseases.
-
Recombinant human interleukin 1 alpha: purification and biological characterization.
-
Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.
-
Redirecting cytotoxic T lymphocyte responses with T-cell receptor transgenes.
-
Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells.
-
Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
-
Regulation of phospholipid biosynthesis in Escherichia coli. Cloning of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase.
-
Relationships among DNA sequences of the 1.3 kb EcoRI family of mouse DNA.
-
Release of amino-terminal fragments from amyloid precursor protein reporter and mutated derivatives in cultured cells.
-
Remarkable conservation of structure among intermediate filament genes.
-
Replication of the murine cytomegalovirus genome: structure and role of the termini in the generation and cleavage of concatenates.
-
Restricted expression of type-II TGF beta receptor in murine embryonic development suggests a central role in tissue modeling and CNS patterning.
-
Retina-specifically expressed novel subtypes of bovine cyclophilin.
-
Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase.
-
Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells.
-
Retroviral DNA integration: viral and cellular determinants of target-site selection.
-
Reverse genetics of Drosophila RNA polymerase II: identification and characterization of RpII140, the genomic locus for the second-largest subunit.
-
RhoA regulates initiation of invagination, but not convergent extension, during sea urchin gastrulation.
-
RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells.
-
Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors.
-
RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage.
-
Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564.
-
Role of molecular biology in hypertension research. State of the Art lecture.
-
Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans.
-
S-allele diversity in a natural population of Physalis crassifolia (Solanaceae) (ground cherry) assessed by RT-PCR.
-
SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.
-
SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa.
-
SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc.
-
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome.
-
Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.
-
Scythe: a novel reaper-binding apoptotic regulator.
-
Selected contribution: a three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue.
-
Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.
-
Selective expression of insulin-like growth factor II in the songbird brain.
-
Selective mutations in cloned and expressed alpha-macroglobulin receptor binding fragment alter binding to either the alpha2-macroglobulin signaling receptor or the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor.
-
Selective regulation of expression of protein kinase C beta isoenzymes occurs via alternative splicing.
-
Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines.
-
Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors.
-
Sequence of a Brassica campestris myrosinase gene.
-
Sequence-independent method for in vitro generation of nested deletions for sequencing large DNA fragments.
-
Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.
-
Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo.
-
Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.
-
Site-directed mutagenesis of recombinant sulfite oxidase: identification of cysteine 207 as a ligand of molybdenum.
-
Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling.
-
Site-directed mutagenesis of the inhibitory subunit of retinal rod cyclic GMP phosphodiesterase.
-
Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
-
Site-specific retinoic acid production in the brain of adult songbirds.
-
Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215.
-
Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis.
-
SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis.
-
Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
-
Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis.
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas.
-
Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport.
-
Structural analysis of the functional sites of class I HLA antigens.
-
Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA.
-
Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ.
-
Structural characterization of the 5' regions of the human phenylalanine hydroxylase gene.
-
Structural features of nephritogenic lupus autoantibodies.
-
Structural organization and chromosomal assignment of the parvalbumin gene.
-
Structural organization and regulation of the chicken estrogen receptor.
-
Structure and expression of a membrane component of the inhibin receptor system.
-
Structure and function of the beta 2-adrenergic receptor--homology with rhodopsin.
-
Structure and function of the ovine type 1 corticotropin releasing factor receptor (CRF1) and a carboxyl-terminal variant.
-
Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues.
-
Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.
-
Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding.
-
Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri.
-
Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
-
Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1).
-
Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils.
-
Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster.
-
Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line.
-
Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution.
-
Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta.
-
Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K).
-
Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein.
-
Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens.
-
Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding.
-
Structures of yeast vesicle trafficking proteins.
-
Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate.
-
Study of the kinetic and physical properties of the orotidine-5'-monophosphate decarboxylase domain from mouse UMP synthase produced in Saccharomyces cerevisiae.
-
Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization.
-
Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae.
-
Subtractive cloning: new genes for studying inflammatory disorders.
-
Subunit IV of cytochrome bc1 complex from Rhodobacter sphaeroides. Localization of regions essential for interaction with the three-subunit core complex.
-
Suppression subtractive hybridization: a versatile method for identifying differentially expressed genes.
-
Synthesis of DNA coding for human proinsulin.
-
Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement.
-
Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support.
-
TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.
-
TRPC3 channels confer cellular memory of recent neuromuscular activity.
-
TRPV1b, a functional human vanilloid receptor splice variant.
-
Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae.
-
Tandemly repeated sequences are present at the ends of the DNA of raccoonpox virus.
-
Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function.
-
The 40-kilodalton allergen of Candida albicans is an alcohol dehydrogenase: molecular cloning and immunological analysis using monoclonal antibodies.
-
The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis.
-
The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.
-
The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway.
-
The Arabidopsis SLEEPY1 gene encodes a putative F-box subunit of an SCF E3 ubiquitin ligase.
-
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.
-
The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.
-
The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein.
-
The Ca2+-binding protein parvalbumin: molecular cloning and developmental regulation of mRNA abundance.
-
The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.
-
The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates.
-
The Erwinia amylovora avrRpt2EA gene contributes to virulence on pear and AvrRpt2EA is recognized by Arabidopsis RPS2 when expressed in pseudomonas syringae.
-
The G185R mutation disrupts function of the iron transporter Nramp2.
-
The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis.
-
The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.
-
The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase.
-
The HrpZ proteins of Pseudomonas syringae pvs. syringae, glycinea, and tomato are encoded by an operon containing Yersinia ysc homologs and elicit the hypersensitive response in tomato but not soybean.
-
The Pseudomonas syringae pv. syringae 61 hrpH product, an envelope protein required for elicitation of the hypersensitive response in plants.
-
The Pseudomonas syringae pv. tomato HrpW protein has domains similar to harpins and pectate lyases and can elicit the plant hypersensitive response and bind to pectate.
-
The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P.
-
The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root.
-
The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling.
-
The SV40 core sequence functions as a repressor element in yeast.
-
The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.
-
The U1 small nuclear ribonucleoprotein (snRNP) 70K protein is transported independently of U1 snRNP particles via a nuclear localization signal in the RNA-binding domain.
-
The UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis utilizes Mn2+ cluster for catalysis.
-
The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor.
-
The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family.
-
The alpha 1C-adrenoceptor in human prostate: cloning, functional expression, and localization to specific prostatic cell types.
-
The androgen-binding protein gene is expressed in CD1 mouse testis.
-
The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling.
-
The aromatase enzyme: from cloning to cancer.
-
The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.
-
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.
-
The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans.
-
The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans.
-
The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus.
-
The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation.
-
The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.
-
The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease. A study of 50 patients.
-
The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.
-
The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants.
-
The functional consequences of genetic variation on tyrosine hydroxylase (TH) expression
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.
-
The generation of ordered sets of cosmid DNA clones from human chromosome region 11p.
-
The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor.
-
The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2.
-
The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.
-
The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution.
-
The human poliovirus receptor. Receptor-virus interaction and parameters of disease specificity.
-
The interleukin 1 receptor.
-
The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.
-
The isolation of ecdysterone inducible genes by hybridization subtraction chromatography.
-
The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
-
The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.
-
The mast cell tumor necrosis factor alpha response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48.
-
The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats.
-
The mouse CD7 gene: identification of a new element common to the human CD7 and mouse Thy-1 promoters.
-
The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.
-
The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori.
-
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.
-
The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.
-
The regulation of proenkephalin expression in a distinct population of glial cells.
-
The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.
-
The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment.
-
The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells.
-
The role of inactivation in open-channel block of the sodium channel: studies with inactivation-deficient mutant channels.
-
The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012.
-
The roles of steroidogenic factor-1 in reproductive function.
-
The second-largest subunit of the poxvirus RNA polymerase is similar to the corresponding subunits of procaryotic and eucaryotic RNA polymerases.
-
The sequence of the reovirus serotype 3 L3 genome segment which encodes the major core protein lambda 1.
-
The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain.
-
The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.
-
The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection.
-
The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.
-
Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel.
-
Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
-
Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family.
-
Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences.
-
Tissue-specific expression of kallikrein-related genes in the rat.
-
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
-
Tissue-specific gene expression in mouse F9 embryonal carcinoma cells: type IV collagen.
-
Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target.
-
Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.
-
Transcription in mouse embryo cells permissively infected by murine cytomegalovirus.
-
Transcription of H-2 and Qa genes in embryonic and adult mice.
-
Transcription of orthopoxvirus telomeres at late times during infection.
-
Transcription of the RelB gene is regulated by NF-kappaB.
-
Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus.
-
Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region.
-
Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-gamma-dependent activation.
-
Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.
-
Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells.
-
Transient elevation of messenger RNA encoding gastrin-releasing peptide, a putative pulmonary growth factor in human fetal lung.
-
Transient expression of a winged-helix protein, MNF-beta, during myogenesis.
-
Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.
-
Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo
-
Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes.
-
Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor.
-
Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.
-
Type 1 neurofibromatosis gene: correction.
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Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.
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U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts.
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Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc.
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Update on the molecular genetics of Duchenne muscular dystrophy.
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Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.
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Use of recombinant adenovirus for metabolic engineering of mammalian cells.
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Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C.
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VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.
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Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.
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Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge.
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Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.
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Verification of a new gene on Saccharomyces cerevisiae chromosome III.
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Virulence genes of poxviruses and reoviruses.
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Vitamin K-dependent protein S in Leydig cells of human testis.
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YbiV from Escherichia coli K12 is a HAD phosphatase.
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Zebrafish Transcription Factor ORFeome for Gene Discovery and Regulatory Network Elucidation.
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alphaSU2, an epithelial integrin that binds laminin in the sea urchin embryo.
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beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors.
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beta-Arrestin: a protein that regulates beta-adrenergic receptor function.
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cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.
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cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.
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cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.
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cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product.
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ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets.
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fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB.
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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
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hrp gene-dependent induction of hin1: a plant gene activated rapidly by both harpins and the avrPto gene-mediated signal.
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mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye.
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p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes.
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pYAC-RC, a yeast artificial chromosome vector for cloning DNA cut with infrequently cutting restriction endonucleases.
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rac, a novel ras-related family of proteins that are botulinum toxin substrates.
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Keywords of People
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Bejsovec, Amy,
Associate Professor of Biology,
Biology
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Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Ciofani, Maria,
Associate Professor of Integrative Immunobiology,
Cell Biology
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Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
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Ferreira, Paulo Alexandre,
Associate Professor in Ophthalmology,
Pathology
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Freemark, Michael Scott,
Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine,
Pediatrics, Endocrinology
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Hilton, Matthew James,
Associate Professor in Orthopaedic Surgery,
Cell Biology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Kelsoe, Garnett H.,
James B. Duke Distinguished Professor of Immunology,
Integrative Immunobiology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Integrative Immunobiology
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Schanberg, Laura Eve,
Professor of Pediatrics,
Pediatrics, Rheumatology
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Shinohara, Mari L.,
Professor of Integrative Immunobiology,
Cell Biology
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Soderling, Scott Haydn,
George Barth Geller Distinguished Professor of Molecular Biology,
Cell Biology
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Taylor, Gregory Alan,
Professor in Medicine,
Integrative Immunobiology
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Wray, Gregory Allan,
Professor of Biology,
Evolutionary Anthropology