Cockroaches

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  Subject Areas on Research

  • A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticides. 
  • A residue in the transmembrane segment 6 of domain I in insect and mammalian sodium channels regulate differential sensitivities to pyrethroid insecticides. 
  • A single amino acid change in the para sodium channel protein is associated with knockdown-resistance (kdr) to pyrethroid insecticides in German cockroach. 
  • A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids. 
  • Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids. 
  • Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. 
  • Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach. 
  • An alanine in segment 3 of domain III (IIIS3) of the cockroach sodium channel contributes to the low pyrethroid sensitivity of an alternative splice variant. 
  • An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel. 
  • Analysis of the action of lidocaine on insect sodium channels. 
  • Associations of neighborhood concentrated poverty, neighborhood racial/ethnic composition, and indoor allergen exposures: a cross-sectional analysis of los angeles households, 2006-2008. 
  • Batrachotoxin, pyrethroids, and BTG 502 share overlapping binding sites on insect sodium channels. 
  • Contamination of nebulizer equipment with cockroach allergen: there's a bug in the system! 
  • Discovery of a Novel Series of Tricyclic Oxadiazine 4a-Methyl Esters Based on Indoxacarb as Potential Sodium Channel Blocker/Modulator Insecticides. 
  • High-frequency steering maneuvers mediated by tactile cues: antennal wall-following in the cockroach. 
  • Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides. 
  • Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. 
  • Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel. 
  • Linkage of kdr-type resistance and the para-homologous sodium channel gene in German cockroaches (Blattella germanica). 
  • Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb. 
  • Molecular determinants on the insect sodium channel for the specific action of type II pyrethroid insecticides. 
  • Mutations in the transmembrane helix S6 of domain IV confer cockroach sodium channel resistance to sodium channel blocker insecticides and local anesthetics. 
  • Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. 
  • Polyzonimine: a Novel Terpenoid Insect Repellant Produced by a Milliped 
  • RNA editing generates tissue-specific sodium channels with distinct gating properties. 
  • Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides. 
  • Synergism of chlorpyrifos against the German cockroach, Blattella germanica. 
  • Synergistic interaction between two cockroach sodium channel mutations and a tobacco budworm sodium channel mutation in reducing channel sensitivity to a pyrethroid insecticide. 
  • kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.