Colchicine

• 

  Subject Areas on Research

  • A requirement for trypsin-sensitive cell-surface components for cell-cell interactions of embryonic neural retina cells. 
  • Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents. 
  • Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents. 
  • Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids. 
  • Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation. 
  • Association of Dapagliflozin Use With Clinical Outcomes and the Introduction of Uric Acid-Lowering Therapy and Colchicine in Patients With Heart Failure With and Without Gout: A Patient-Level Pooled Meta-analysis of DAPA-HF and DELIVER. 
  • Benzodiazepine receptor increases after repeated seizures: evidence for localization to dentate granule cells. 
  • Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells-in vitro and ex vivo study. 
  • Characteristics of clinical trials evaluating cardiovascular therapies for Coronavirus Disease 2019 Registered on ClinicalTrials.gov: a cross sectional analysis. 
  • Characterization of moesin in the sea urchin Lytechinus variegatus: redistribution to the plasma membrane following fertilization is inhibited by cytochalasin B. 
  • Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis. 
  • Colchicine administered into the area of the nucleus basalis decreases cortical nicotinic cholinergic receptors labelled by [3H]-acetylcholine. 
  • Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial. 
  • Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial. 
  • Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial. 
  • Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial. 
  • Colchicine--Update on mechanisms of action and therapeutic uses. 
  • Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. 
  • Effects of colchicine and cytochalasin B on hypertonicity-induced changes in toad urinary bladder. 
  • Effects of colchicine and cytochalasin B on vasopressin- and cyclic adenosine monophosphate-induced changes in toad urinary bladder. 
  • Effects of pentoxifylline administration on blood viscosity and leukocyte cytoskeletal function in patients with intermittent claudication. 
  • Efficacy and safety of Ixekizumab vs. low-dose IL-2 vs. Colchicine vs. standard of care in the treatment of patients hospitalized with moderate-to-critical COVID-19: A pilot randomized clinical trial (STRUCK: Survival Trial Using Cytokine Inhibitors). 
  • Evidence for colchicine binding protein in Mycobacterium smegmatis. 
  • Evidence implicating dentate granule cells in development of entorhinal kindling. 
  • Evidence implicating dentate granule cells in wet dog shakes produced by kindling stimulations of entorhinal cortex. 
  • Fibrillar systems in cell motility. 
  • From the editor: Margaritaville blues and Philadelphia news. 
  • Function of microtubules under inadequate protein diet. 
  • Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves. 
  • Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells. 
  • Fura-2 transport in toad urinary bladder epithelium: effects of antidiuretic hormone, colchicine and osmotic gradients. 
  • Glutamic acid decarboxylase-containing neurons in the dorsal column nuclei of the cat. 
  • Growth and lability of Chaetopterus oocyte mitotic spindles isolated in the presence of porcine brain tubulin. 
  • Guanosinetriphosphatase activity of tubulin associated with microtubule assembly. 
  • Human lymphocyte motility: normal characteristics and anomalous behavior of chronic lymphocytic leukemia cells. 
  • Human lymphocyte surface immunoglobulin capping. Normal characteristics and anomalous behavior of chronic lymphocytic leukemic lymphocytes. 
  • Impact of glomerular filtration rate in colchicine toxicity. 
  • Inflammation as a Treatment Target after Acute Myocardial Infarction. 
  • Influence of cytoskeletal assembly on phosphatidylcholine synthesis in intact phagocytic cells. 
  • Intradentate colchicine retards the development of amygdala kindling. 
  • Involvement of microtubules and 10-nm filaments in the movement and positioning of nuclei in syncytia. 
  • Kainic acid neurotoxicity toward hippocampal formation: dependence on specific excitatory pathways. 
  • Long-term colchicine administration leading to colchicine toxicity and death. 
  • Medical management of acute gout. 
  • Microtubule disruption leads to cellular contraction in human trabecular meshwork cells. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Necrotizing Sweet Syndrome of the Upper Extremity After Elective Hand Surgery. 
  • Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. 
  • Polycation-induced assembly of purified tubulin. 
  • Properties of prostatic cultures transformed by SV40. 
  • Protective effects of mossy fiber lesions against kainic acid-induced seizures and neuronal degeneration. 
  • Receptor-mediated endocytosis of carcinoembryonic antigen by rat alveolar macrophages in vitro. 
  • Relationship between movement and aggregation of centrioles in syncytia and formation of microtubule bundles. 
  • Serum retinol binding protein secretion through microtubules in chicks. 
  • Severe systemic inflammatory response syndrome immediately after spinal surgery in a patient with axial gout. 
  • Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain. 
  • The Beneficial Therapy with Colchicine for Atherosclerosis via Anti-inflammation and Decrease in Hypertriglyceridemia. 
  • The current state of care in gout: Addressing the need for better understanding of an ancient disease. 
  • The impact of familial Mediterranean fever on women's health. 
• 

  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology