Colitis

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  Subject Areas on Research

  • A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells. 
  • A functional genomics predictive network model identifies regulators of inflammatory bowel disease. 
  • Aberrant expression of maspin in idiopathic inflammatory bowel disease is associated with disease activity and neoplastic transformation. 
  • Antagonism of toxigenic Clostridium difficile by nontoxigenic C. difficile. 
  • Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase. 
  • Bacteriotherapy for clostridium difficile colitis. 
  • Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance. 
  • Clinical, Imaging Findings, Responses, and Outcomes of Patients With Classical Hodgkin Lymphoma and Non-Hodgkin Lymphoma Undergoing Immune Checkpoint Inhibitor Therapy: A Single-Institution Experience. 
  • Clostridium Difficile Infection from a Surgical Perspective. 
  • Colitis cystica profunda: a pediatric case report. 
  • Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer. 
  • Control of IFN-alphaA by CD73: implications for mucosal inflammation. 
  • Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2. 
  • Cooccurrence of collagenous colitis with seronegative spondyloarthropathy: report of a case and literature review. 
  • Dextran sulfate sodium-induced colitis in immunodeficient rats. 
  • Dietary Salt Exacerbates Experimental Colitis. 
  • Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis. 
  • Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. 
  • Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme. 
  • Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair. 
  • Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. 
  • Double Negativity for Expression of YAP1 and CDX2 Defines an Aggressive Type of Colitis-associated Cancer. 
  • Duct Diameter and Size of Stones Predict Successful Extracorporeal Shock Wave Lithotripsy and Endoscopic Clearance in Patients With Chronic Pancreatitis and Pancreaticolithiasis. 
  • Enhanced expression of mast cell growth factor and mast cell activation in the bladder following the resolution of trinitrobenzenesulfonic acid (TNBS) colitis in female rats. 
  • Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice. 
  • Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. 
  • Eosinophils alter colonic epithelial barrier function: role for major basic protein. 
  • Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. 
  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. 
  • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. 
  • Extrinsic surgical denervation ameliorates TNBS-induced colitis in rats. 
  • Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid. 
  • Functional gastrointestinal disorders in inflammatory bowel disease: Time for a paradigm shift? 
  • GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity. 
  • Gastrointestinal milk intolerance of infancy. 
  • Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models. 
  • Gnotobiotic models for study of the microbial ecology of Clostridium difficile and Escherichia coli. 
  • IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse model. 
  • Imaging and clinical manifestations of immune checkpoint inhibitor-related colitis in cancer patients treated with monotherapy or combination therapy. 
  • Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum. 
  • Inflammasome, Inflammation, and Tissue Homeostasis. 
  • Inhibition of Clostridium difficile toxin A-induced colitis in rats by APAZA. 
  • Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis. 
  • Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. 
  • Intestinal and hepatic complications of human bone marrow transplantation. Part II. 
  • Introduction: Regulatory B Cell Special Issue-making all the pieces fit. 
  • Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation. 
  • Isolated recto-sigmoid colitis: a new imaging pattern of ipilimumab-associated colitis. 
  • Long-Term Outcomes in Indeterminate Colitis Patients Undergoing Ileal Pouch-Anal Anastomosis: Function, Quality of Life, and Complications. 
  • Macrophages driven to a novel state of activation have anti-inflammatory properties in mice. 
  • Managing toxicities of phosphatidylinositol-3-kinase (PI3K) inhibitors. 
  • MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation. 
  • Moving beyond microbiome-wide associations to causal microbe identification. 
  • Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. 
  • NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. 
  • Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice. 
  • Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. 
  • Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice. 
  • Persistence of proctitis in 2 cases of clindamycin-associated colitis. 
  • Piroxicam treatment of IL-10-deficient mice enhances colonic epithelial apoptosis and mucosal exposure to intestinal bacteria. 
  • Prevalence and significance of inflammatory bowel disease-like morphologic features in collagenous and lymphocytic colitis. 
  • Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon. 
  • Sequential clinical and histopathological changes in collagenous and lymphocytic colitis over time. 
  • Simple Clinical Colitis Activity Index: Accurate Assessment of Inflammatory Burden or Reflection of Low Mood and Somatoform Behavior? 
  • Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. 
  • Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice. 
  • TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function. 
  • Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. 
  • The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. 
  • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. 
  • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. 
  • The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. 
  • The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. 
  • The role of thrombin and protease-activated receptors in pain mechanisms. 
  • The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis. 
  • The terminal ileum is affected in patients with lymphocytic or collagenous colitis. 
  • Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease. 
  • Type I interferon signaling restrains IL-10R+ colonic macrophages and dendritic cells and leads to more severe Salmonella colitis. 
  • Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study. 
  • Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner. 
  • Variable Pringle Maneuvers and Effect on Intestinal Epithelium in Rats. A Pilot Experimental Study in Rats. 
  • Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats. 
  • What Clues Can We Use From Primary Sclerosing Cholangitis With Inflammatory Bowel Disease Phenotypes? 
  • c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. 
  • miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation. 
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  Keywords of People

  • Karhausen, Jorn, Adjunct Associate Professor in the Department of Anesthesiology, Anesthesiology, Cardiothoracic