Colonic Neoplasms

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  Subject Areas on Research

  • A Bayesian approach to joint feature selection and classifier design. 
  • A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon. 
  • A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. 
  • A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion. 
  • A carcinoembryonic antigen (CEA) binding protein from ascites influences CEA uptake by macrophages. 
  • A case of curative-intent hepatectomy for colon cancer metastatic to the scapula and liver. 
  • A comparison of antiangiogenic therapies for the prevention of liver metastases. 
  • A comparison of laparoscopically assisted and open colectomy for colon cancer. 
  • A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. 
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. 
  • A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. 
  • A metabolic signature of colon cancer initiating cells. 
  • A multigene prognostic assay for selection of adjuvant chemotherapy in patients with T3, stage II colon cancer: impact on quality-adjusted life expectancy and costs. 
  • A novel murine model of inflammatory bowel disease and inflammation-associated colon cancer with ulcerative colitis-like features. 
  • A phase 1 dose-escalation study of NEO-102 in patients with refractory colon and pancreatic cancer. 
  • A phase I trial of recombinant human interleukin-1 beta alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer. 
  • A population-based comparison of adenocarcinoma of the large and small intestine: insights into a rare disease. 
  • A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers. 
  • A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. 
  • A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model. 
  • A usability problem: conveying health risks to consumers on the Internet. 
  • Absence of a relationship of size of primary colon carcinoma with metastasis and survival. 
  • Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival. 
  • Active specific immunotherapy of Dukes B2 and C colorectal carcinoma: comparison of two doses of the vaccine. 
  • Acute decompensation after removing a central line: practical approaches to increasing safety in the intensive care unit. 
  • Acute pain associated with oxaliplatin infusion: case report and literature review. 
  • Adjuvant chemotherapy for t1 node-positive colon cancers provides significant survival benefit. 
  • Adjuvant postoperative radiation therapy for colonic carcinoma. 
  • Adolescent colorectal cancer and dioxin exposure. 
  • Adult Patients' Perspectives on the Benefits and Harms of Overused Screening Tests: a Qualitative Study. 
  • Advanced fellowship training is associated with improved lymph node retrieval in colon cancer resections. 
  • Advanced neoplasia in Veterans at screening colonoscopy using the National Cancer Institute Risk Assessment Tool. 
  • Age and comorbidity association with survival outcomes in metastatic colorectal cancer: CALGB 80405 analysis. 
  • Age differences in care practices and outcomes for hospitalized patients with cancer. 
  • Aging and neoplasia. 
  • Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene. 
  • An informatics tool to assess colon cancer risk. 
  • An integrated indenter-ARFI imaging system for tissue stiffness quantification. 
  • Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison. 
  • Analysis of factors associated with the tumorigenic potential of 12 tumor clones derived from a single rat colon adenocarcinoma. 
  • Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001. 
  • Analysis of the relationship between stage of differentiation and NK/LAK susceptibility of colon carcinoma cells. 
  • Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. 
  • Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. 
  • Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. 
  • Antigen retrieval, blocking, detection and visualisation systems in immunohistochemistry: a review and practical evaluation of tyramide and rolling circle amplification systems. 
  • Antineoplastic activity of boron-containing thymidine nucleosides in Tmolt3 leukemic cells. 
  • Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells. 
  • Are metaplasias in colorectal adenomas truly metaplasias? 
  • Are preferences for equity over efficiency in health care allocation "all or nothing"? 
  • Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. 
  • Assessing the quality of colorectal cancer care: do we have appropriate quality measures? (A systematic review of literature). 
  • Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance). 
  • Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer. 
  • Association of Inflammatory Biomarkers With Survival Among Patients With Stage III Colon Cancer. 
  • Association of Survival With Adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors After Colon Cancer Diagnosis: The CALGB 89803/Alliance Trial. 
  • Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803. 
  • Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. 
  • Association of family history with cancer recurrence and survival among patients with stage III colon cancer. 
  • Associations Between Unprocessed Red Meat and Processed Meat With Risk of Recurrence and Mortality in Patients With Stage III Colon Cancer. 
  • Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance). 
  • Big Data, Small Effects. 
  • Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer. 
  • Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in cancer and leukemia group B (CALGB) 9581. 
  • CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver. 
  • COX-2 polymorphism, use of nonsteroidal anti-inflammatory drugs, and risk of colon cancer in African Americans (United States). 
  • CT colonography for detection of colon polyps and cancer. 
  • Cabozantinib with or without Panitumumab for RAS wild-type metastatic colorectal cancer: impact of MET amplification on clinical outcomes and circulating biomarkers. 
  • Can the localization of primary colonic tumors be improved by staging CT without specific bowel preparation compared to optical colonoscopy? 
  • Cancer Screening Results and Follow-up Using Routinely Collected Electronic Health Data: Estimates for Breast, Colon, and Cervical Cancer Screenings. 
  • Cancer and pregnancy: the clinician's perspective. 
  • Cancer vaccines in colon and rectal cancer over the last decade: lessons learned and future directions. 
  • Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions. 
  • Case report. Intrabiliary colonic metastasis mimicking primary biliary neoplasia. 
  • Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells. 
  • Chemotherapy in the elderly. 
  • Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. 
  • Clinical development and evaluation of a VEGF-D assay in plasma from patients with metastatic colorectal cancer in the RAISE study. 
  • Clonality of combined tumors. 
  • Cloning efficiency of cultured human tumor cell lines measured with the use of a Coulter particle counter. 
  • Clustered cancer cells show a distinct adhesion behavior from single cell form under physiological shear conditions. 
  • Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects. 
  • Co-expression of urokinase with haptoglobin in human carcinomas. 
  • Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). 
  • Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology. 
  • Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. 
  • Colon cancer screening in the elderly: when do we stop? 
  • Colon cancer with microsatellite instability in a 13-year-old Hispanic male. 
  • Colon cancer, version 3.2014. 
  • Colon cancer. 
  • Colon cancer. 
  • Colon sentinel lymph node mapping: practical surgical applications. 
  • Colonic schwannoma visualized on FDG PET/CT. 
  • Colonoscopy as a primary diagnostic procedure in chronic gastrointestinal tract bleeding. 
  • Colonoscopy withdrawal time and risk of neoplasia at 5 years: results from VA Cooperative Studies Program 380. 
  • Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation. 
  • Colorectal cancer: adjuvant chemotherapy for rectal cancer-an unresolved issue. 
  • Combination gene therapy for liver metastasis of colon carcinoma in vivo. 
  • Combined modality therapy for rectal and colon cancer. 
  • Comparative effectiveness of i-SCAN™ and high-definition white light characterizing small colonic polyps. 
  • Comparing a medical records-based and a claims-based index for measuring comorbidity in patients with lung or colon cancer. 
  • Comparison of adverse events during 5-fluorouracil versus 5-fluorouracil/oxaliplatin adjuvant chemotherapy for stage III colon cancer: a population-based analysis. 
  • Comparison of survival of stage I-III colon cancer by travel distance and hospital volume. 
  • Computed tomography colonography: colon examination or Pandora's box. 
  • Computerized tomographic colonography: performance evaluation in a retrospective multicenter setting. 
  • Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer. 
  • Controversies regarding laparoscopic colectomy for malignant diseases. 
  • Cost-effectiveness analysis and budget constraints. 
  • Cost-effectiveness analysis in a setting of budget constraints--is it equitable? 
  • CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. 
  • Creatine and phosphocreatine analogs: anticancer activity and enzymatic analysis. 
  • Criteria for the diagnosis of dysplasia by endoscopic optical coherence tomography. 
  • Current immunotherapeutic strategies in colon cancer. 
  • Current status of therapy of solid tumors: brain tumor therapy. 
  • Cytologic studies of glucose-6-phosphate dehydrogenase in malignancy. 
  • D6.1, a murine antimelanoma monoclonal antibody from congenitally athymic nude mice immunized with purified melanoma tumor-associated antigen. 
  • DNA repair: a double-edged sword. 
  • Decreased synthesis of matrix metalloproteinase-7 and adhesion to the extracellular matrix proteins of human colon cancer cells treated with troglitazone. 
  • Delay in Adjuvant Chemotherapy and Survival Advantage in Stage III Colon Cancer. 
  • Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. 
  • Detecting colorectal cancer in stool with the use of multiple genetic targets. 
  • Determining the Optimal Timing for Initiation of Adjuvant Chemotherapy After Resection for Stage II and III Colon Cancer. 
  • Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy. 
  • Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. 
  • Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach. 
  • Diagnosis and Treatment of ERBB2-Positive Metastatic Colorectal Cancer: A Review. 
  • Diagnosis and surgical treatment of colonic endometriosis. 
  • Diet- and Lifestyle-Based Prediction Models to Estimate Cancer Recurrence and Death in Patients With Stage III Colon Cancer (CALGB 89803/Alliance). 
  • Dietary Fat Intake after Colon Cancer Diagnosis in Relation to Cancer Recurrence and Survival: CALGB 89803 (Alliance). 
  • Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance). 
  • Dietary fat in relation to all-cause mortality and cancer progression and death among people with metastatic colorectal cancer: Data from CALGB 80405 (Alliance)/SWOG 80405. 
  • Dietary glycemic load and cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. 
  • Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis. 
  • Differential adhesion of rat colon carcinoma cells to fibronectin in relation to their tumorigenicity. 
  • Differential effects of parenteral nutrition on tumor growth and erythrocyte polyamine levels in the rat. 
  • Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues. 
  • Differential production of high molecular weight sulfated glycoproteins in normal colonic mucosa, primary colon carcinoma, and metastases. 
  • Direct in vivo measurement of targeted binding in a human tumor xenograft. 
  • Direct invasion of the transverse colon by a cecal tumor. 
  • Disease-associated casein kinase I delta mutation may promote adenomatous polyps formation via a Wnt/beta-catenin independent mechanism. 
  • Disparity of Colon Cancer Outcomes in Rural America: Making the Case to Travel the Extra Mile. 
  • Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability. 
  • Documenting the natural history of patients with resected stage II adenocarcinoma of the colon after random assignment to adjuvant treatment with edrecolomab or observation: results from CALGB 9581. 
  • Does Conversion in Laparoscopic Colectomy Portend an Inferior Oncologic Outcome? Results from 104,400 Patients. 
  • Does postoperative irradiation play a role in the adjuvant therapy of stage T4 colon cancer? 
  • Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. 
  • Duration of Adjuvant Chemotherapy for Stage III Colon Cancer. 
  • E-selectin can mediate the arrest type of adhesion of colon cancer cells under physiological shear flow. 
  • Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial. 
  • Effect of Diagnosis on Outcomes in the Setting of Enhanced Recovery Protocols. 
  • Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials. 
  • Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. 
  • Effect of preoperative irradiation on resectability of colorectal carcinomas. 
  • Effect of surgeon specialization on long-term survival following colon cancer resection at an NCI-designated cancer center. 
  • Effect of virtual reality on time perception in patients receiving chemotherapy. 
  • Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival From Colon Cancer: A United States Population-Based Study. 
  • Efficacy and safety of dilpacimab (ABT-165) versus bevacizumab plus FOLFIRI in metastatic colorectal cancer: a phase II study. 
  • Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors. 
  • Electrophoretic analysis of four high molecular weight sialoglycoproteins produced by metastatic human colon carcinoma cells. 
  • Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy. 
  • Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. 
  • Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers. 
  • Epigenetic silencing of genes in human colon cancer. 
  • Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma. 
  • Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. 
  • Expression of proliferation-specific genes in the mucosa adjacent to colon carcinoma. 
  • Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. 
  • F-18-FDG-PET/CT imaging of small cell carcinoma of the colon. 
  • FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density. 
  • Failure of monoclonal antibodies against tumor associated antigens to improve tumor targeting of LAK cells in a model of rat colon carcinoma. 
  • Failure patterns following curative resection of colonic carcinoma. 
  • Fc-mOX40L fusion protein produces complete remission and enhanced survival in 2 murine tumor models. 
  • Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients. 
  • Frequent BRAF mutations suggest a novel oncogenic driver in colonic neuroendocrine carcinoma. 
  • GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers. 
  • GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome. 
  • Gastrointestinal hemorrhage. 
  • Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes. 
  • Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer. 
  • Giant colonic lipoma as lead point for intermittent colo-colonic intussusception. 
  • Growth kinetics of human colorectal carcinoma. 
  • Guidelines 2000 for colon and rectal cancer surgery. 
  • Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. 
  • HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. 
  • Helicobacter typhlonius and Helicobacter rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL10-deficient mice. 
  • Hemolytic anemia and metastatic carcinoma: case report and literature review. 
  • High rates of metachronous colon cancer or dysplasia after segmental resection or subtotal colectomy in Crohn's colitis. 
  • High-dose human lymphoblastoid interferon in metastatic colorectal cancer: clinical results and modification of biological responses. 
  • High-dose, single-agent irinotecan as first-line therapy in the treatment of metastatic colorectal cancer. 
  • High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. 
  • High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors. 
  • Hospital-level compliance with the commission on cancer's quality of care measures and the association with patient survival. 
  • How good is screening for colorectal cancer? 
  • Human colon cancer cells express multiple glycoprotein ligands for E-selectin. 
  • Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments. 
  • Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis. 
  • Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse. 
  • IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. 
  • Immunogenicity and Optimal Timing of 13-Valent Pneumococcal Conjugate Vaccination during Adjuvant Chemotherapy in Gastric and Colorectal Cancer: A Randomized Controlled Trial. 
  • Immunohistochemical expression of mutant p53 oncogene in transitional mucosa adjacent to human colon cancer. 
  • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. 
  • Impact of Patents and Licensing Practices on Access to Genetic Testing for Inherited Susceptibility to Cancer: Comparing Breast and Ovarian Cancers to Colon Cancers 
  • Impact of Primary Tumor Laterality on Adjuvant Hepatic Artery Infusion Pump Chemotherapy in Resected Colon Cancer Liver Metastases: Analysis of 487 Patients. 
  • Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. 
  • Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. 
  • Impact of smoking on patients with stage III colon cancer: results from Cancer and Leukemia Group B 89803. 
  • Impact of synchronized anti-PD-1 with Ad-CEA vaccination on inhibition of colon cancer growth. 
  • Impact of the Cancer Risk Intake System on patient-clinician discussions of tamoxifen, genetic counseling, and colonoscopy. 
  • Implementing survivorship care plans for colon cancer survivors 
  • Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets. 
  • In vivo selection of tumor-targeting RNA motifs. 
  • Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody. 
  • Increased serum levels of macrophage colony-stimulating factor in ovarian cancer. 
  • Increased transversions in a novel mutator colon cancer cell line. 
  • Indications for adjuvant radiotherapy in extrapelvic colonic carcinoma. 
  • Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. 
  • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. 
  • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. 
  • Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. 
  • Inflammatory pseudotumour of the colon. 
  • Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522. 
  • Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. 
  • Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen. 
  • Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. 
  • Intracorporeal ileocolic anastomosis: a review. 
  • Intrathoracic metastasis from an extrathoracic malignancy: a radiographic approach to patient evaluation. 
  • Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. 
  • Involvement of histo-blood-group antigens in the susceptibility of colon carcinoma cells to natural killer-mediated cytotoxicity. 
  • Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. 
  • Is intraoperative lymph node mapping and sentinel lymph node biopsy for colorectal carcinoma necessary? 
  • Isolated metastatic melanoma to the colon mimicking colon cancer. 
  • John Foster Dulles, his medical history and its impact on Cold War politics. 
  • KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. 
  • Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death. 
  • Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow. 
  • Laparoscopic colectomy for cancer: a favorable opinion. 
  • Laparoscopic colectomy for cancer: an oncologic feasible option. 
  • Laparoscopic colon resection for cancer. 
  • Laparoscopic ileostomy and colostomy. 
  • Laparoscopic resection for colon cancer--the end of the beginning? 
  • Laser-induced fluorescence spectroscopy: somewhere over the rainbow. 
  • Leiomyoma involving the gastrocolic ligament: CT demonstration. 
  • Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. 
  • Liposomal 64Cu-PET Imaging of Anti-VEGF Drug Effects on Liposomal Delivery to Colon Cancer Xenografts. 
  • Local failure following curative resection of colonic adenocarcinoma. 
  • Localization of I-131-labeled goat and primate anti-carcinoembryonic antigen(CEA) antibodies in patients with cancer. 
  • Localized colon cancer, version 3.2013: featured updates to the NCCN Guidelines. 
  • Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio. 
  • Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets. 
  • Loss of KAI1 expression in the progression of colorectal cancer. 
  • Low levels of BRCA1 protein expression predict a worse prognosis in stage I-II colon cancer. 
  • Lower Adenoma Miss Rate of Computer-Aided Detection-Assisted Colonoscopy vs Routine White-Light Colonoscopy in a Prospective Tandem Study. 
  • MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. 
  • MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. 
  • Marine ω-3 Polyunsaturated Fatty Acid and Fish Intake after Colon Cancer Diagnosis and Survival: CALGB 89803 (Alliance). 
  • Marital Status, Living Arrangement, and Cancer Recurrence and Survival in Patients with Stage III Colon Cancer: Findings from CALGB 89803 (Alliance). 
  • Mesenchymal stem cells support growth and organization of host-liver colorectal-tumor organoids and possibly resistance to chemotherapy. 
  • Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line. 
  • Metastatic behavior and cell surface properties of HT-29 human colon carcinoma variant cells selected for their differential expression of sialyl-dimeric Le(x)-antigen. 
  • Metastatic colon cancer, version 3.2013: featured updates to the NCCN Guidelines. 
  • Metastatic leiomyosarcoma diagnosed on routine screening colonoscopy. 
  • Metastatic potential of colon carcinoma. Expression of ABO/Lewis-related antigens. 
  • Metastatic potential of human colon cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production. 
  • Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancer--a study of CALGB 9581 and 89803. 
  • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. 
  • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. 
  • Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. 
  • Molecular analysis of genetic instability caused by chronic inflammation. 
  • Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases. 
  • More on Data Sharing. 
  • Multifocal inflammatory leukoencephalopathy after fluorouracil and levamisole therapy for colon cancer. 
  • Multiple calcium-mediated effector mechanisms regulate chloride secretory responses in T84-cells. 
  • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. 
  • Muscle oxidative capacity during IL-6-dependent cancer cachexia. 
  • NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells. 
  • NCCN Clinical Practice Guidelines in Oncology: colon cancer. 
  • NCCN Guidelines Insights: Colon Cancer, Version 2.2018. 
  • NCCN Guidelines Insights: Rectal Cancer, Version 6.2020. 
  • Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis. 
  • Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice. 
  • Neuroradiology case of the day. Multifocal inflammatory leukoencephalopathy due to treatment with 5-fluorouracil and levamisole. 
  • New approaches to assessing and treating early-stage colon and rectal cancer: summary statement from 2007 Santa Monica Conference. 
  • Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth. 
  • Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice. 
  • Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). 
  • Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation. 
  • Obstructive and perforative colonic carcinoma: patterns of failure. 
  • Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses. 
  • Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation. 
  • Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. 
  • Over-pressure suppresses ultrasonic-induced drug uptake. 
  • Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. 
  • Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT). 
  • Patient expectations of benefit from phase I clinical trials: linguistic considerations in diagnosing a therapeutic misconception. 
  • Patient, Physician, and Procedure Characteristics Are Independently Predictive of Polyp Detection Rates in Clinical Practice. 
  • Patient-derived micro-organospheres enable clinical precision oncology. 
  • Patients with cancer and their spouse caregivers. Perceptions of the illness experience. 
  • Patterns of Biologics Use Across Treatment Lines in Elderly (Age >65) Medicare Patients With Metastatic Colon Cancer. 
  • Peptidyl membrane-interactive molecules are cytotoxic to prostatic cancer cells in vitro. 
  • Perioperative blood transfusion in patients with colon carcinoma. 
  • Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. 
  • Peritoneal carcinomatosis: preoperative CT with intraperitoneal contrast material. 
  • Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma. 
  • Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity. 
  • Phase II study of fludarabine phosphate in patients with advanced colorectal carcinoma. 
  • Phase II trial of lymphoblastoid interferon in metastatic colon carcinoma. 
  • Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130. 
  • Phosphatidic acid modulates Cl- secretion in T84 cells: varying effects depending on mode of stimulation. 
  • Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. 
  • Physical Activity in Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance). 
  • Physician Non-adherence to Colonoscopy Interval Guidelines in the Veterans Affairs Healthcare System. 
  • Physicians recommend different treatments for patients than they would choose for themselves. 
  • Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance). 
  • Plasma thrombopoietic activity in humans with normal and abnormal platelet counts. 
  • Postoperative radiation therapy for high-risk colon carcinoma. 
  • Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect. 
  • Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance). 
  • Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial. 
  • Preference for equity as a framing effect. 
  • Preliminary analysis of a randomized comparison of 5-fluorouracil versus 5-fluorouracil and high-dose continuous-infusion folinic acid in disseminated colorectal cancer. 
  • Preneoplastic lesions induced by myc and src oncogenes in a heterotopic rat colon. 
  • Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. 
  • Prevalence and predictors of multiple behavioral risk factors for colon cancer. 
  • Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial. 
  • Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer. 
  • Prospective comparison of patient experience with colon imaging tests. 
  • Prospective multicenter trial of staging adequacy in colon cancer: preliminary results. 
  • Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy. 
  • Quantitative laser scanning confocal autofluorescence microscopy of normal, premalignant, and malignant colonic tissues. 
  • Race, Income, and Survival in Stage III Colon Cancer: CALGB 89803 (Alliance). 
  • Racial and Ethnic Disparities in Colon Cancer Screening in North Carolina. 
  • Radiation therapy for resectable colon cancer. Is there a role in the modern chemotherapy era? 
  • Radiologic, endoscopic, and surgical considerations of melanoma metastatic to the gastrointestinal tract. 
  • Radiosensitive orbital metastasis as presentation of occult colonic adenocarcinoma. 
  • Randomized study of continuous infusion fluorouracil versus fluorouracil plus cisplatin in patients with metastatic colorectal cancer. 
  • Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors. 
  • Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. 
  • Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. 
  • Relationship between sensitivity to natural killer cells and MHC class-I antigen expression in colon carcinoma cell lines. 
  • Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803. 
  • Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats. 
  • Relationships between sclerosing cholangitis, inflammatory bowel disease, and cancer in patients undergoing liver transplantation. 
  • Relative effectiveness and safety of chemotherapy in elderly and nonelderly patients with stage III colon cancer: a systematic review. 
  • Reply to L. Casadaban et al. 
  • Reply to S. Sorscher. 
  • Resection of Carcinoid Tumor Metastatic to the Right Ventricle and Tricuspid Valve. 
  • Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity. 
  • Review. Colon cancer vaccines: an update. 
  • Risk of colorectal neoplasm in patients with acromegaly and its relationship with serum growth hormone levels. 
  • Risk perception measures' associations with behavior intentions, affect, and cognition following colon cancer screening messages. 
  • Role of Adjuvant Radiotherapy in Locally Advanced Colonic Carcinoma in the Modern Chemotherapy Era. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis. 
  • Sensitivity of the Hemoccult II slide test in detecting colonic neoplasms. 
  • Sentinel node staging of resectable colon cancer: results of a multicenter study. 
  • Serum protein profiling using an aptamer array predicts clinical outcomes of stage IIA colon cancer: A leave-one-out crossvalidation. 
  • Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases. 
  • Significance of a fall in serum CEA concentration in patients treated with cytotoxic chemotherapy for disseminated colorectal cancer. 
  • Single-incision laparoscopic right colectomy: an efficient technique. 
  • Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells. 
  • Sonic hedgehog signaling pathway supports cancer cell growth during cancer radiotherapy. 
  • Sp1 regulates osteopontin expression in SW480 human colon adenocarcinoma cells. 
  • Spectroscopic optical coherence tomography for classification of colorectal cancer in a mouse model. 
  • Status of colon cancer vaccines. [An interview with Michael Morse by H&O]. 
  • Structure of the human MutSalpha DNA lesion recognition complex. 
  • Studying health histories of cancer: a new model connecting cancer incidence and survival. 
  • Substituting ornithine for arginine in total parenteral nutrition eliminates enhanced tumor growth. 
  • Successful desensitization to oxaliplatin. 
  • Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB 89803 (Alliance). 
  • Suppressor of fused negatively regulates beta-catenin signaling. 
  • Surgical experience of colon resection in the extreme elderly. 
  • Survival after hepatic resection for metastatic colorectal cancer: trends in outcomes for 1,600 patients during two decades at a single institution. 
  • Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405. 
  • Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers. 
  • Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. 
  • Systemic nitric oxide production in human malaria. II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen expression. 
  • Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth. 
  • Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer. 
  • TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts. 
  • TP53 and RAS mutations in metachronous tumors from patients with cancer of the upper aerodigestive tract. 
  • Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors. 
  • Targeted cytotoxic somatostatin analogue AN-238 inhibits somatostatin receptor-positive experimental colon cancers independently of their p53 status. 
  • Targeted suppression of beta-catenin blocks intestinal adenoma formation in APC Min mice. 
  • Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. 
  • Tea intake and risk of colon cancer in African-Americans and whites: North Carolina colon cancer study. 
  • Telephone monitoring of distress in patients aged 65 years or older with advanced stage cancer: a cancer and leukemia group B study. 
  • Template for reporting results of biomarker testing of specimens from patients with carcinoma of the colon and rectum. 
  • Ten or More Cumulative Lifetime Adenomas Are Associated with Increased Risk for Advanced Neoplasia and Colorectal Cancer. 
  • The ALPPS procedure as a novel "liver-first" approach in treating liver metastases of colon cancer: the first experience in Greek Cypriot area. 
  • The CLN3 gene is a novel molecular target for cancer drug discovery. 
  • The Diet of Higher Insulinemic Potential Is Not Associated with Worse Survival in Patients with Stage III Colon Cancer (Alliance). 
  • The Impact of Primary Tumor Location on Long-Term Survival in Patients Undergoing Hepatic Resection for Metastatic Colon Cancer. 
  • The differential expression of statin in the nuclei of human colonic crypts adjacent to a cancer: an immunohistochemical study. 
  • The epidemiology of tea consumption and colorectal cancer incidence. 
  • The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. 
  • The influence of cost-effectiveness information on physicians' cancer screening recommendations. 
  • The natural history of colorectal carcinoma in adolescents. 
  • The relationship of collagenolytic activity to stage of human colorectal carcinoma. 
  • The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells. 
  • The side of the primary tumor affects overall survival in colon adenocarcinoma: an analysis of the national cancer database. 
  • The surgeon and adjuvant therapy for stage II colon cancer. 
  • The utility of micro-CT and MRI in the assessment of longitudinal growth of liver metastases in a preclinical model of colon carcinoma. 
  • Thoracic empyema associated with recurrent colon cancer: report of a case and review of the literature. 
  • Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report. 
  • Three-dimensional imaging of xenograft tumors using optical computed and emission tomography. 
  • Time from positive screening fecal occult blood test to colonoscopy and risk of neoplasia. 
  • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. 
  • Treatment of Metastatic Colorectal Cancer: ASCO Guideline. 
  • Treatment of primary colon cancer with peritoneal carcinomatosis: comparison of concomitant vs. delayed management. 
  • Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. 
  • Tumor necrosis factor alpha and colitis-associated colon cancer. 
  • Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. 
  • Type III TGF-β receptor enhances colon cancer cell migration and anchorage-independent growth. 
  • Ulex europeus agglutinin I-reactive high molecular weight glycoproteins of adenocarcinoma of distal colon and rectum and their possible relationship with metastatic potential. 
  • Understanding the role of cancer worry in creating a "teachable moment" for multiple risk factor reduction. 
  • Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner. 
  • Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice. 
  • Use of molecular biomarkers to inform adjuvant therapy for colon cancer. 
  • Use of nonsteroidal antiinflammatory drugs and risk of colon cancer in a population-based, case-control study of African Americans and Whites. 
  • Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs. 
  • Virtual reality: a distraction intervention for chemotherapy. 
  • Virus-based therapies for colon cancer. 
  • Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis. 
  • Weight Loss and/or Sulindac Mitigate Obesity-associated Transcriptome, Microbiome, and Protumor Effects in a Murine Model of Colon Cancer. 
  • Wild-type p53 is a cell cycle checkpoint determinant following irradiation. 
  • With Colorectal Cancer Treatment, Physical Toxicity Is Not the Only Concern. 
  • With widespread adoption of MIS colectomy for colon cancer, does hospital type matter? 
  • [Intraportal injection of specific monoclonal antibody in nude mice with liver metastasis]. 
  • [Metastatic sites of colonic adenocarcinoma in the ORL system: 2 cases]. 
  • p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. 
• 

  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute