Complement Pathway, Classical

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  Subject Areas on Research

  • IgG and complement-mediated tissue damage in the absence of C2: evidence of a functionally active C2-bypass pathway in a guinea pig model. 
  • Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway. 
  • Regulation of the B cell response to T-dependent antigens by classical pathway complement.