Complement C3

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  Subject Areas on Research

  • A six-month-old boy with neonatal lupus and cardiac enlargement. 
  • Absence of hyperacute rejection in newborn pig-to-baboon cardiac xenografts. 
  • Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors. 
  • Antidouble stranded DNA antibody assays in systemic lupus erythematosus: correlations of longitudinal antibody measurements. 
  • Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression. 
  • Basement membrane antibody with skin bullae. 
  • C3 complement inhibition prevents antibody-mediated rejection and prolongs renal allograft survival in sensitized non-human primates. 
  • Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. 
  • Chronic cicatrizing conjunctivitis in a patient with epidermolysis bullosa acquisita. 
  • Circulating IgA immune complexes in patients with psoriasis. 
  • Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. 
  • Complement and CD4+ T cells drive context-specific corneal sensory neuropathy. 
  • Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes. 
  • Cutaneous polyarteritis nodosa. Report of a case associated with Crohn's disease. 
  • Dermatitis herpetiformis. 
  • Dermatomyositis associated with IgA deposition. 
  • Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells. 
  • Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen. 
  • Disseminated intravascular coagulation: a reappraisal. 
  • Epstein Barr virus binding induces internalization of the C3d receptor: a novel immunotoxin delivery system. 
  • Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody. 
  • Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice. 
  • Fate of four cadaveric donor renal allografts with mesangial IgA deposits. 
  • Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement. 
  • Hepatic transplantation into sensitized recipients. Demonstration of hyperacute rejection. 
  • Hostility, anger, and depression predict increases in C3 over a 10-year period. 
  • Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. 
  • Human lymphocyte complement receptors. Quantitative requirements for C3 of normal and chronic lymphocyte leukemia lymphocytes. 
  • Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • IgA immune complexes in patients with dermatitis herpetiformis occur in the absence of IgA rheumatoid factor. 
  • IgA-containing circulating immune complexes in dermatitis herpetiformis, Henoch-Schönlein purpura, systemic lupus erythematosus and other diseases. 
  • Immune function during intravenous administration of a soybean oil emulsion. 
  • Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma. 
  • Immunoglobulin prevents complement-mediated hyperacute rejection in swine-to-primate xenotransplantation. 
  • Immunopathological and clinical studies in herpes gestationis. 
  • Impact of Baseline Characteristics on Geographic Atrophy Progression in the FILLY Trial Evaluating the Complement C3 Inhibitor Pegcetacoplan. 
  • Leishmania species: mechanisms of complement activation by five strains of promastigotes. 
  • Localization of cloned unique DNA to three different regions of chromosome 19: screen for linkage probes for myotonic dystrophy. 
  • Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure. 
  • Newborn discordant cardiac xenotransplantation in primates: a model of natural antibody depletion. 
  • Novel Immunoassay for Complement Activation by PF4/Heparin Complexes. 
  • Ocular cicatricial pemphigoid with granular IgA and complement deposition. 
  • Pulsed methylprednisolone therapy compared to high dose prednisone in systemic lupus erythematosus nephritis. 
  • Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties. 
  • Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules. 
  • Regulation of the B cell response to T-dependent antigens by classical pathway complement. 
  • Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia. 
  • Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. 
  • Spectrum of humoral rejection after pediatric heart transplantation. 
  • The ARMS2 A69S variant and bilateral advanced age-related macular degeneration. 
  • The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosus. 
  • The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. 
  • The phagocytic cell: summary. 
  • The third component of complement: covalent attachment of a radioactive sugar to the labile binding site of C3 via the alternative pathway. 
  • Thrombotic microangiopathy in anti-glomerular basement membrane glomerulonephritis. 
  • Xanthogranulomatous pyelonephritis in renal transplant recipient. 
  • [A severe course of bullous pemphigoid in a young man].