Complement C8

• 

  Subject Areas on Research

  • Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. 
  • Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. 
  • Neisseria meningitidis and Neisseria gonorrhoeae bacteremia associated with C6, C7, or C8 deficiency. 
  • Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal disease. 
  • Underlying complement deficiency in patients with disseminated gonococcal infection.