Coronary Circulation

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  Subject Areas on Research

  • "Mirror-lake" serial relationship of electrocardiographic and biochemical indices for the detection of reperfusion and the prediction of salvage in patients with acute myocardial infarction. 
  • 23Na MRI combined with contrast-enhanced 1H MRI provides in vivo characterization of infarct healing. 
  • A magnetization-driven gradient echo pulse sequence for the study of myocardial perfusion. 
  • A method for quantitating antifibrillatory effects of drugs after coronary reperfusion in dogs: improved outcome with bretylium. 
  • A rationale for the use of sequential coronary artery bypass grafts. 
  • A technical problem in the calculation of laminar flow near irregular surfaces described by sampled geometric data. 
  • ACCF/ASNC appropriateness criteria for single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI): a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group and the American Society of Nuclear Cardiology endorsed by the American Heart Association. 
  • Aborted myocardial infarction after primary percutaneous coronary intervention: magnetic resonance imaging insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. 
  • Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction. 
  • Acceptance, panic, and partial recovery the pattern of usage of drug-eluting stents after introduction in the U.S. (a report from the American College of Cardiology/National Cardiovascular Data Registry). 
  • Acquired coronary-to-bronchial artery communication: a possible cause of coronary steal. 
  • Activation in the region of parabrachial nucleus elicits neurogenically mediated coronary vasoconstriction. 
  • Acute effects of ethanol on myocardial blood flow in the nonischemic and ischemic heart. 
  • Adenosine A(3)-receptor stimulation attenuates postischemic dysfunction through K(ATP) channels. 
  • Adjunctive transcutaneous ultrasound with thrombolysis: results of the PLUS (Perfusion by ThromboLytic and UltraSound) trial. 
  • Alterations of myocardial blood flow associated with experimental canine left ventricular hypertrophy secondary to valvular aortic stenosis. 
  • An unexpected flow abnormality. 
  • Angiogenic potential of perivascularly delivered aFGF in a porcine model of chronic myocardial ischemia. 
  • Animal models for protecting ischemic myocardium: results of the NHLBI Cooperative Study. Comparison of unconscious and conscious dog models. 
  • Aortic counterpulsation: a review of the hemodynamic effects and indications for use. 
  • Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy. 
  • Assessing flow during minimally invasive coronary artery bypass: an Allen's test equivalent. 
  • Assessment of Coronary Blood Flow by Transesophageal Echocardiography. 
  • Assessment of coronary reperfusion after thrombolysis with a model combining myoglobin, creatine kinase-MB, and clinical variables. TAMI-7 Study Group. Thrombolysis and Angioplasty in Myocardial Infarction-7. 
  • Assessment of microvascular injury after acute myocardial infarction: importance of the area at risk. 
  • Assessment of myocardial perfusion during CABG surgery with two-dimensional transesophageal contrast echocardiography. 
  • Assessment of no-reflow regions using cardiac MRI. 
  • Assessment of retrograde cardioplegia distribution using contrast echocardiography. 
  • Assessment of the myocardium on 2-phase cardiac multidetector computed tomography: does cyclic cardiac contraction influence myocardial attenuation? 
  • Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy. 
  • Association between platelet receptor occupancy after eptifibatide (integrilin) therapy and patency, myocardial perfusion, and ST-segment resolution among patients with ST-segment-elevation myocardial infarction: an INTEGRITI (Integrilin and Tenecteplase in Acute Myocardial Infarction) substudy. 
  • Association of TIMI myocardial perfusion grade and ST-segment resolution with cardiovascular magnetic resonance measures of microvascular obstruction and infarct size following ST-segment elevation myocardial infarction. 
  • Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction. 
  • Association of smoking with improved myocardial perfusion and the angiographic characterization of myocardial tissue perfusion after fibrinolytic therapy for ST-segment elevation myocardial infarction. 
  • Asymmetric-echo, short TE, retrospectively gated MR imaging of the heart and pulmonary vessels. 
  • Augmentation and redistribution of myocardial blood flow during acute ischemia by intraaortic balloon pumping. 
  • Augmentation of coronary collateral blood flow in acute myocardial infarction. 
  • Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: a comparison of angiographic, echocardiographic and coronary flow parameters. 
  • Bradyarrhythmias in acute myocardial infarction. 
  • CMR First-Pass Perfusion for Suspected Inducible Myocardial Ischemia. 
  • Calpain inhibition improves collateral-dependent perfusion in a hypercholesterolemic swine model of chronic myocardial ischemia. 
  • Calpain inhibition modulates glycogen synthase kinase 3β pathways in ischemic myocardium: A proteomic and mechanistic analysis. 
  • Capillary reserve in isometrically contracting dog hearts. 
  • Cardiac cryosurgery: regional myocardial blood flow of ventricular cryolesions. 
  • Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary results. 
  • Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts. 
  • Cardiac renin-angiotensin system. Molecular and functional aspects. 
  • Cardiovascular effects of alcohol with particular reference to the heart. 
  • Case 2--1997. On-line contrast echocardiographic assessment of myocardial perfusion: its role in minimally invasive coronary artery bypass procedures. 
  • Changes in myocardial perfusion reserve after PTCA: noninvasive assessment with positron tomography. 
  • Characteristics of chronic left ventricular hypertrophy induced by subcoronary valvular aortic stenosis. I. Myocardial blood flow and metabolism. 
  • Characteristics of chronic left ventricular hypertrophy induced by subcoronary valvular aortic stenosis. II. Response to ischemia. 
  • Characterization of 3-Dimensional PET Systems for Accurate Quantification of Myocardial Blood Flow. 
  • Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC. 
  • Clinical perspectives on reperfusion injury in acute myocardial infarction. 
  • Clinical predictors of early infarct-related artery patency following thrombolytic therapy: importance of body weight, smoking history, infarct-related artery and choice of thrombolytic regimen: the GUSTO-I experience. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries. 
  • Clinical significance of perfusion defects by thallium-201 single photon emission tomography following oral dipyridamole early after coronary angioplasty. 
  • Clinical significance of post-procedural TIMI flow in patients with cardiogenic shock undergoing primary percutaneous coronary intervention. 
  • Clinical utility of serial and continuous ST-segment recovery assessment in patients with acute ST-elevation myocardial infarction: assessing the dynamics of epicardial and myocardial reperfusion. 
  • Collateral conductance changes during a brief coronary occlusion in awake dogs. 
  • Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial. 
  • Combined Tc-99m sestamibi first-pass radionuclide angiography and cardiac SPECT imaging during arbutamine infusion delivered by a computerized closed-loop system. 
  • Combined prognostic utility of ST-segment recovery and myocardial blush after primary percutaneous coronary intervention in acute myocardial infarction. 
  • Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coronary collateral development and the arterial response to injury. 
  • Comparing off-pump and on-pump clinical outcomes and costs for diabetic cardiac surgery patients. 
  • Comparison of 180 degrees and 360 degrees data collection in thallium-20 1 imaging using single-photon emission computerized tomography (SPECT): concise communication. 
  • Comparison of physiological motion filters for in vivo cardiac ARFI. 
  • Comparison of technetium-99m sestamibi and thallium-201 retention characteristics in canine myocardium. 
  • Complement factor 1 inhibitor improves cardiopulmonary function in neonatal cardiopulmonary bypass. 
  • Compressed sensing reconstruction for undersampled breath-hold radial cine imaging with auxiliary free-breathing data. 
  • Computer-assisted quantification of myocardial reperfusion after primary percutaneous coronary intervention predicts functional and contrast-enhanced cardiovascular magnetic resonance outcomes in patients with ST-segment elevation myocardial infarction. 
  • Conduction block after cardioplegic arrest: prevention by augmented atrial hypothermia. 
  • Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion. 
  • Coronary and systemic haemodynamic effects of bretylium in the intact unanaesthetized dog. 
  • Coronary and systemic hemodynamic effects of dopamine in the awake dog. 
  • Coronary and transmural myocardial blood flow responses in awake domestic pigs. 
  • Coronary artery angioplasty with a helical autoperfusion balloon catheter. 
  • Coronary artery hemodynamics after aorto-coronary artery vein bypass. An experimental evaluation. 
  • Coronary blood flow in chronic insulin-dependent diabetic dogs. 
  • Coronary collateral blood flow in acute myocardial infarction. 
  • Coronary collateral circulation during stress and the effects of aorta-coronary bypass grafts. 
  • Coronary cyclic flow variations following primary angioplasty is associated with poor short-term prognosis. 
  • Coronary flow and regional function before and after supraarterial myotomy for myocardial bridging. 
  • Coronary input impedance is constant during systole and diastole. 
  • Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase. 
  • Coronary vasodilation after a single ventricular extra-activation in the conscious dog. 
  • Cryosurgery for cardiac arrhythmias: acute and chronic effects on coronary arteries. 
  • Cyclic coronary flow: defining preinfarction angina at the crossroads of unstable angina and myocardial infarction. 
  • Demonstration of coronary artery myogenic vasoconstriction in the awake dog. 
  • Demonstration of dissimilar acute haemodynamic effects of ethanol and acetaldehyde. 
  • Detecting obstructive coronary disease with CT angiography and noninvasive fractional flow reserve. 
  • Detection of pulmonary venous flow by pulsed Doppler echocardiography in children. 
  • Development of coronary collateral circulation in left circumflex Ameroid-occluded swine myocardium. 
  • Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. 
  • Diastolic coronary resistance and capacitance are independent of the duration of diastole. 
  • Diastolic right ventricular filling vortex in normal and volume overload states. 
  • Different effects of prolonged exercise on the right and left ventricles. 
  • Differential ventricular ischemic injury: an experimental model of right ventricular failure with a variable degree of left ventricular dysfunction. 
  • Differentiation of viable and nonviable myocardium by the use of three-dimensional tagged MRI in 2-day-old reperfused canine infarcts. 
  • Direct myocardial revascularization and angiogenesis--how many patients might be eligible? 
  • Dissociation between global and regional systolic and diastolic ventricular function during coronary occlusion and reperfusion. 
  • Distinction between metabolic and myogenic mechanisms of coronary hyperemic response to brief diastolic occlusion. 
  • Doppler evaluation of homograft valved conduits in children. 
  • Double negatives. 
  • Dynamic mechanisms of cardiac oxygenation during brief ischemia and reperfusion. 
  • Early assessment of myocardial salvage by contrast-enhanced magnetic resonance imaging. 
  • Echocardiographic Confirmation of Coronary Blood Flow. 
  • Effect of adenosine on transmural myocardial blood flow distribution in the awake dog. 
  • Effect of alpha-adrenergic stimulation on regional contractile function and myocardial blood flow with and without ischemia. 
  • Effect of atrial fibrillation on atrial blood flow in conscious dogs. 
  • Effect of atrial natriuretic factor on transmural myocardial blood flow distribution in the dog. 
  • Effect of brief myocardial ischemia on sympathetic coronary vasoconstriction. 
  • Effect of eptifibatide on coronary flow reserve following coronary stent implantation (an ESPRIT substudy). Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy. 
  • Effect of estrogen replacement therapy on corrected thrombolysis in myocardial infarction frame count. 
  • Effect of heart rate on myocardial blood flow in dogs with left ventricular hypertrophy. 
  • Effect of left ventricular hypertrophy on myocardial capillary perfusion. 
  • Effect of nitroglycerin on myocardial collateral conductance in awake dogs. 
  • Effect of phosphodiesterase type 5 inhibition on microvascular coronary dysfunction in women: a Women's Ischemia Syndrome Evaluation (WISE) ancillary study. 
  • Effect of the right ventricular isolation procedure on ventricular vulnerability to fibrillation. 
  • Effects of arterial hypertension on myocardial recovery after ischemic injury. 
  • Effects of atrial fibrillation on myocardial blood flow in the ischemic heart of the dog. 
  • Effects of atrial natriuretic peptide on the coronary arterial vasculature in humans. 
  • Effects of barium-induced cardiac contraction on large- and small-vessel intramyocardial blood volume. 
  • Effects of delay in administration of potassium cardioplegia to the isolated rat heart. 
  • Effects of diphenylhydantoin on coronary and systemic haemodynamics in awake dogs. 
  • Effects of global ischemia on the diastolic properties of the left ventricle in the conscious dog. 
  • Effects of increased myocardial oxygen consumption on coronary reactive hyperemia in the awake dog. 
  • Effects of ischemia on left ventricular regional function in the conscious dog. 
  • Effects of magnesium chloride on cardiovascular hemodynamics in the neurally intact dog. 
  • Effects of myocardial water exchange on T1 enhancement during bolus administration of MR contrast agents. 
  • Effects of nitroglycerin and propranolol on the distribution of transmural myocardial blood flow during ischemia in the absence of hemodynamic changes in the unanesthetized dog. 
  • Effects of nitroglycerin on transmural myocardial blood flow in the unanesthetized dog. 
  • Effects of positive-pressure ventilation, pericardial effusion, and cardiac tamponade on respiratory variation in transmitral flow velocities. 
  • Effects of propranolol on myocardial blood flow during transient ischemia in the awake dog. 
  • Effects of propranolol on the hemodynamic, coronary sinus blood flow and myocardial metabolic response to atrial pacing. 
  • Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure. 
  • Effects of pulmonary embolism on regional myocardial blood flow. 
  • Effects of sample volume location, imaging view, heart rate and age on tricuspid velocimetry in normal subjects. 
  • Effects of triiodothyronine and vasopressin on cardiac function and myocardial blood flow after brain death. 
  • Effects of water exchange on the measurement of myocardial perfusion using paramagnetic contrast agents. 
  • Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia. 
  • Emergency coronary artery bypass surgery preserves global and regional left ventricular function after intravenous tissue plasminogen activator therapy for acute myocardial infarction. 
  • Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. II. Effects on regional myocardial blood flow. 
  • Endothelial function in patients with slow coronary flow and normal coronary angiography. 
  • Enhancement of cardiac function by cyclocreatine in models of cardiopulmonary bypass. 
  • Estimation of myocardial blood flow for longitudinal studies with 13N-labeled ammonia and positron emission tomography. 
  • Evidence for myogenic vasomotor activity in the coronary circulation. 
  • Experimental evaluation of coronary hemodynamics after aorto-coronary bypass. 
  • Experimental infarct size as a function of the amount of myocardium at risk. 
  • Facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention: design and rationale of the Facilitated Intervention with Enhanced Reperfusion Speed to Stop Events (FINESSE) trial. 
  • Failure of simple clinical measurements to predict perfusion status after intravenous thrombolysis. 
  • Feasibility and applicability of computer-assisted myocardial blush quantification after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. 
  • Feasibility of 19F imaging of perfluorochemical emulsions to measure myocardial vascular volume. 
  • Finite element modelling of pulsatile blood flow in idealized model of human aortic arch: study of hypotension and hypertension. 
  • First-pass entry of nonionic contrast agent into the myocardial extravascular space. Effects on radiographic estimates of transit time and blood volume. 
  • Frequency, correlates, and clinical implications of myocardial perfusion after primary angioplasty and stenting, with and without glycoprotein IIb/IIIa inhibition, in acute myocardial infarction. 
  • Functional and reactive hyperemia are unaltered by homocysteine in conscious dogs. 
  • Fusion of aortic valve commissures in patients supported by a continuous axial flow left ventricular assist device. 
  • Gender Differences in Radiation Dose From Nuclear Cardiology Studies Across the World: Findings From the INCAPS Registry. 
  • Gender and acute myocardial infarction: is there a different response to thrombolysis? 
  • Glycogen Synthase Kinase 3β Inhibition Improves Myocardial Angiogenesis and Perfusion in a Swine Model of Metabolic Syndrome. 
  • Glycoprotein IIb/IIIa inhibitors: therapeutic applications in acute ST-segment elevation myocardial infarction. 
  • Grade 3 ischemia on the admission electrocardiogram predicts rapid progression of necrosis over time and less myocardial salvage by primary angioplasty. 
  • Graded exercise stress tests in angiographically documented coronary artery disease. 
  • Heart and kidneys: sharing more than just blood. 
  • Hemodynamic and myocardial blood flow. Profiles of pinacidil and nitroprusside in conscious dogs. 
  • Hemodynamic effects of prolonged hyperoxia. 
  • Hemodynamic indices of myocardial dysfunction correlate with dipyridamole thallium-201 SPECT. 
  • High-Sensitivity Troponin in Patients With Coronary Artery Endothelial Dysfunction. 
  • Human pathologic correlation with PET in ischemic and nonischemic cardiomyopathy. 
  • Hyperemic response of the coronary circulation to brief diastolic occlusion in the conscious dog. 
  • Hyperemic response to coronary occlusion during a single diastole in conscious dog. 
  • Identification, imaging, functional assessment and management of congenital coronary arterial abnormalities in children. 
  • Images in cardiovascular medicine. Constrictive pericarditis. 
  • Impact of collateral flow on myocardial reperfusion and infarct size in patients undergoing primary angioplasty for acute myocardial infarction. 
  • Impact of nonculprit vessel myocardial perfusion on outcomes of patients undergoing percutaneous coronary intervention for acute coronary syndromes: analysis from the ACUITY trial (Acute Catheterization and Urgent Intervention Triage Strategy). 
  • Impact of time to treatment on myocardial reperfusion and infarct size with primary percutaneous coronary intervention for acute myocardial infarction (from the EMERALD Trial). 
  • Impaired endothelial function in coronary heart disease patients with depressive symptomatology. 
  • Implications of ventricular arrhythmia "bursts" with normal epicardial flow, myocardial blush, and ST-segment recovery in anterior ST-elevation myocardial infarction reperfusion: a biosignature of direct myocellular injury "downstream of downstream". 
  • Importance of total ischemic time and preprocedural infarct-related artery blood flow in predicting infarct size in patients with anterior wall myocardial infarction (from the CRISP-AMI Trial). 
  • Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. 
  • Improved near-term coronary artery disease risk classification with gated stress myocardial perfusion SPECT. 
  • Improved perfusion and contractile reserve after transmyocardial laser revascularization in a model of hibernating myocardium. 
  • In vivo imaging of rat coronary arteries using bi-plane digital subtraction angiography. 
  • In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development. 
  • Incidence and outcomes of no-reflow phenomenon during percutaneous coronary intervention among patients with acute myocardial infarction. 
  • Incomplete relaxation between beats after myocardial hypoxia and ischemia. 
  • Increase in myocardial collateral blood flow during repeated brief episodes of ischemia in the awake dog. 
  • Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation. 
  • Incremental prognostic value of RNA ejection fraction measurements during pharmacologic stress testing: a comparison with clinical and perfusion variables. 
  • Influence of transducer frequency and imaging modality on the intraoperative assessment of myocardial perfusion with transesophageal echocardiography. 
  • Insights into the change in brain natriuretic peptide after ST-elevation myocardial infarction (STEMI): why should it be better than baseline? 
  • Interatrial shunting in atrial septal aneurysm. 
  • Intracoronary basic fibroblast growth factor enhances myocardial collateral perfusion in dogs. 
  • Intramyocardial and intracoronary basic fibroblast growth factor in porcine hibernating myocardium: a comparative study. 
  • Intramyocardial, autologous CD34+ cell therapy for refractory angina. 
  • Intraoperative contrast echocardiography: a direct approach to measure regional myocardial perfusion. 
  • Intraoperative perfusion contrast echocardiography. Initial experience during coronary artery bypass grafting. 
  • Intraoperative relationships between regional myocardial distribution of bypass graft flow and the coronary collateral circulation. 
  • Intraoperative transesophageal color flow mapping: initial experience. 
  • Intravenous nitroglycerin infusion inhibits cyclic blood flow responses caused by periodic platelet thrombus formation in stenosed canine coronary arteries. 
  • Invited Commentary. 
  • Is chronically dysfunctional yet viable myocardium distal to a severe coronary stenosis hypoperfused? 
  • Ischemic hibernating myocardium demonstrated by positron emission tomography in anomalous origin of the left coronary artery from the pulmonary artery. 
  • Left and codominant coronary artery circulations are associated with higher in-hospital mortality among patients undergoing percutaneous coronary intervention for acute coronary syndromes: report From the National Cardiovascular Database Cath Percutaneous Coronary Intervention (CathPCI) Registry. 
  • Left ventricular filling pressure after aorto-coronary grafting. 
  • Left ventricular myocardial blood flow, metabolism, and effects of treatment with enalapril: further insights into the mechanisms of canine experimental pacing-induced heart failure. 
  • Left-sided stellate ganglion ablation or "rate-controlled" vagal nerve stimulation decreases regional myocardial metabolic impairment during acute ischemia in dogs. 
  • Limitation of the coronary vascular response to ischemia in the awake dog. 
  • Limits of detection of regional differences in vasodilated flow in viable myocardium by first-pass magnetic resonance perfusion imaging. 
  • Linear relationship between the distribution of thallium-201 and blood flow in ischemic and nonischemic myocardium during exercise. 
  • Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. 
  • Link between the angiographic substudy and mortality outcomes in a large randomized trial of myocardial reperfusion. Importance of early and complete infarct artery reperfusion. GUSTO-I Investigators. 
  • Local administration of L-703,081 using a composite polymeric stent reduces platelet deposition in canine coronary arteries. 
  • Local effects of acute cellular injury on regional myocardial blood flow. 
  • Long-term survival from acute myocardial infarction: salutary effect of an open coronary vessel. 
  • Lymphatic angiogenesis induced by transmyocardial laser revascularization. 
  • MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS-325. 
  • MRI quantitative myocardial perfusion with compartmental analysis: a rest and stress study. 
  • MRXCAT: Realistic numerical phantoms for cardiovascular magnetic resonance. 
  • Magnetic resonance versus radionuclide pharmacological stress perfusion imaging for flow-limiting stenoses of varying severity. 
  • Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. 
  • Matrix metalloproteinases in patients with myocardial infarction and percutaneous revascularization. 
  • Measurement of myocardial perfusion by contrast echocardiography: application in the operating room. 
  • Mechanical support as failure intervention in patients with cavopulmonary shunts (MFICS): rationale and aims of a new registry of mechanical circulatory support in single ventricle patients. 
  • Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction. 
  • Metabolic mediation of single brief diastolic occlusion reactive hyperemic responses. 
  • Metabolism of preconditioned myocardium: effect of loss and reinstatement of cardioprotection. 
  • Methods and value of pulsatile blood flow measurements in man. 
  • MicroRNA-145 restores contractile vascular smooth muscle phenotype and coronary collateral growth in the metabolic syndrome. 
  • Microvascular integrity and the time course of myocardial sodium accumulation after acute infarction. 
  • Models for coronary pressure-flow relationships. 
  • Myocardial blood flow and function during gradual coronary occlusion in awake dog. 
  • Myocardial blood flow and oxygen consumption in the empty-beating, fibrillating, and potassium-arrested hypertrophied canine heart. 
  • Myocardial blood flow distribution during ischemia-induced coronary vasodilation in the unanesthetized dog. 
  • Myocardial blood flow distribution in concentric left ventricular hypertrophy. 
  • Myocardial blood flow in awake dogs with chronic tricuspid regurgitation. 
  • Myocardial cell hypertrophy after myocardial infarction with reperfusion in dogs. 
  • Myocardial clearance kinetics of technetium-99m-SQ30217: a marker of regional myocardial blood flow. 
  • Myocardial contractile reserve and perfusion defect severity with rest and stress dobutamine (99m)Tc-sestamibi SPECT in canine stunning and subendocardial infarction. 
  • Myocardial distribution of cardioplegic solution after retrograde delivery in patients undergoing cardiac surgical procedures. 
  • Myocardial energetics and blood flow in acute rapid ventricular pacing. 
  • Myocardial function and transmural blood flow during coronary venous retroperfusion in pigs. 
  • Myocardial hibernation and stunning: still much to learn. 
  • Myocardial oxygenation in dogs during partial and complete coronary artery occlusion. 
  • Myocardial perfusion and ventricular function measurements during total coronary artery occlusion in humans. A comparison with rest and exercise radionuclide studies. 
  • Myocardial perfusion changes in patients irradiated for left-sided breast cancer and correlation with coronary artery distribution. 
  • Myocardial procainamide concentration in canine atria and ventricles. 
  • Myocardial protection during coronary angioplasty with an autoperfusion balloon catheter in humans. 
  • Myocardial protection. 
  • Myocardial uptake and clearance of T1-201 in healthy subjects: comparison of adenosine-induced hyperemia and exercise stress. 
  • Neurogenic influences on the coronary vascular response to ischemia in the awake dog. 
  • Noninvasive radionuclide procedures for diagnosis and management of myocardial ischemia. 
  • Nonobstructive chronic cannulation of the left circumflex coronary artery of the dog. 
  • Norwood reconstruction using continuous coronary perfusion: a safe and translatable technique. 
  • Optimal characterization of myocardial perfusion with AngioMARK. 
  • Optimizing rotational atherectomy in high-risk percutaneous coronary interventions: insights from the PROTECT ΙΙ study. 
  • Origin of atrial coving in canine phasic coronary artery blood flow. 
  • Outcome prediction in patients at high risk for coronary artery disease: comparison between 99mTc tetrofosmin and 99mTc sestamibi. 
  • Outcomes of primary stenting for acute myocardial infarction. 
  • Paracrine mechanisms in adult stem cell signaling and therapy. 
  • Pathophysiology of cardiac extracorporeal membrane oxygenation. 
  • Perfusion and function assessment by nuclear cardiology techniques. 
  • Perfusion balloon catheter. 
  • Perioperative cardiac imaging. 
  • Persistent diastolic dysfunction despite complete systolic functional recovery after reperfused acute myocardial infarction demonstrated by tagged magnetic resonance imaging. 
  • Pexelizumab and infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary Intervention: a delayed enhancement cardiac magnetic resonance substudy from the APEX-AMI trial. 
  • Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution. 
  • Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine. 
  • Pharmacotherapy: Intracoronary streptokinase in acute myocardial infarction. 
  • Phase plane analysis of left ventricular hemodynamics. 
  • Physiologic determinants of coronary blood flow during external cardiac massage. 
  • Physiologic straws in the wind: in which direction do they bend? 
  • Physiologic--angiographic correlates of coronary arterial stenoses in resting and intensely vasodilated states. 
  • Physiological and psychological variables predict compliance to prescribed exercise therapy in patients recovering from myocardial infarction. 
  • Physiological basis of myocardial contrast enhancement in fast magnetic resonance images of 2-day-old reperfused canine infarcts. 
  • Pitfalls in myocardial perfusion assessment with dynamic MR imaging after administration of a contrast material bolus in dogs. 
  • Plasma N-terminal fragment of the prohormone B-type natriuretic peptide concentrations in relation to time to treatment and Thrombolysis in Myocardial Infarction (TIMI) flow: a substudy of the Assessment of the Safety and Efficacy of a New Treatment Strategy with Percutaneous Coronary Intervention (ASSENT IV-PCI) trial. 
  • Platelet inhibition to target reperfusion injury trial: Rationale and study design. 
  • Poor performance of lead V5 in single- and dual-channel ST-segment monitoring during coronary occlusion. 
  • Poststress measurements of left ventricular function with gated perfusion SPECT: comparison with resting measurements by using a same-day perfusion-function protocol. 
  • Prediction of severe coronary artery disease by combined rest and exercise radionuclide angiocardiography and tomographic perfusion imaging with technetium 99m-labeled sestamibi: a comparison with clinical and electrocardiographic data. 
  • Principal strain orientation in the normal human left ventricle. 
  • Procainamide delivery to ischemic canine myocardium following rapid intravenous administration. 
  • Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction: the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial. 
  • Prognostic value of PET myocardial perfusion imaging in obese patients. 
  • Prognostic value of a coronary artery jeopardy score. 
  • Prognostic value of thallium-201 single-photon emission computed tomography for patients with multivessel coronary artery disease after revascularization (the Emory Angioplasty versus Surgery Trial [EAST]). 
  • Prolonged myocardial nucleotide depletion after brief ischemia in the open-chest dog. 
  • Pulmonary venous wedge pressure provides a safe and accurate estimate of pulmonary arterial pressure in children with shunt-dependent pulmonary blood flow. 
  • Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion. 
  • Quantification of myocardial hypoperfusion with 99m Tc-sestamibi in patients undergoing prolonged coronary artery balloon occlusion. 
  • Quantification of myocardial perfusion by MRI after coronary occlusion. 
  • Quantifying Myocardial Contractility Changes Using Ultrasound-Based Shear Wave Elastography. 
  • Quantitation of ischemia during total coronary occlusion with computer-assisted high resolution ST-segment monitoring: effect of collateral flow. 
  • Quantitative measurement of blood flow dynamics in embryonic vasculature using spectral Doppler velocimetry. 
  • RV functional imaging: 3-D echo-derived dynamic geometry and flow field simulations. 
  • Radionuclide angiocardiography in the diagnosis of congenital heart disorders. 
  • Radionuclide ventricular function analysis. 
  • Randomized comparison of primary percutaneous coronary intervention with combined proximal embolic protection and thrombus aspiration versus primary percutaneous coronary intervention alone in ST-segment elevation myocardial infarction: the PREPARE (PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-Elevation) study. 
  • Rapid measurements of diastolic intramyocardial vascular volume. 
  • Real-time three-dimensional intracardiac echocardiography. 
  • Recovery of systolic and diastolic left ventricular function after a 60-second coronary arterial occlusion during percutaneous transluminal coronary angioplasty for angina pectoris. 
  • Redistribution of canine left ventricular myocardial blood flow in unloaded systole. 
  • Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol. 
  • Regional atrial blood flow in dogs. Effect of hypertrophy on coronary flow reserve. 
  • Regional blood flow in canine atria during exercise. 
  • Regional myocardial blood flow after sudden aortic constriction in awake dogs. 
  • Regional myocardial blood flow during graded treadmill exercise in the dog. 
  • Regional myocardial blood flow in awake dogs. 
  • Regional vascular reserve in canine atria and ventricles during rest and exercise. 
  • Relation between leucocyte count, myonecrosis, myocardial perfusion, and outcomes following primary angioplasty. 
  • Relation between myocardial perfusion and left ventricular function following acute coronary occlusion: disproportionate effects of anterior vs. inferior ischemia. 
  • Relation between radionuclide angiographic regional ejection fraction and left ventricular regional ischemia in awake dogs. 
  • Relation of coronary artery stenosis and pressure gradient to exercise-induced ischemia before and after coronary angioplasty. 
  • Relation of impaired Thrombolysis In Myocardial Infarction myocardial perfusion grades to residual thrombus following the restoration of epicardial patency in ST-elevation myocardial infarction. 
  • Relationship between blood flow to ischemic regions and extent of myocardial infarction. Serial measurement of blood flow to ischemic regions in dogs. 
  • Relationship between infarct artery location, epicardial flow, and myocardial perfusion after primary percutaneous revascularization in acute myocardial infarction. 
  • Relationship between ischemic contracture and mitochondrial function. 
  • Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials. 
  • Relationship between retinal arteriolar narrowing and myocardial perfusion: multi-ethnic study of atherosclerosis. 
  • Relationship of T2-Weighted MRI Myocardial Hyperintensity and the Ischemic Area-At-Risk. 
  • Relationship of creatine kinase-myocardial band release to Thrombolysis in Myocardial Infarction perfusion grade after intracoronary stent placement: an ESPRIT substudy. 
  • Remodeling and reparation of the cardiovascular system. 
  • Reperfusion ventricular arrhythmia bursts identify larger infarct size in spite of optimal epicardial and microvascular reperfusion using cardiac magnetic resonance imaging. 
  • Reverse redistribution on exercise thallium scintigraphy: relationship to coronary patency and ventricular function after myocardial infarction. 
  • Right ventricular free wall isolation: effects on regional myocardial blood flow. 
  • Right ventricular sensitivity to metabolic injury during cardiopulmonary bypass. 
  • Role of Volume Redistribution in the Congestion of Heart Failure. 
  • Role of mitochondrial aldehyde dehydrogenase in nitroglycerin-induced vasodilation of coronary and systemic vessels: an intact canine model. 
  • Role of resting thallium201 perfusion in predicting coronary anatomy, left ventricular wall motion, and hospital outcome in unstable angina pectoris. 
  • Roles of collateral arterial flow and ischemic preconditioning in protection of acutely ischemic myocardium. 
  • ST-segment resolution and outcome in myocardial infarction. 
  • Serial thallium-201 imaging at rest in patients with unstable and stable angina pectoris: relationship of myocardial perfusion at rest to presenting clinical syndrome. 
  • Serum release of the creatine kinase tissue-specific isoforms MM3 and MB2 is simultaneous during myocardial reperfusion. 
  • Shifting the open-artery hypothesis downstream: the quest for optimal reperfusion. 
  • Short and long term effect of adjunctive intra-aortic balloon pump use for patients undergoing high risk reperfusion therapy: a meta-analysis of 10 international randomised trials. 
  • Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. 
  • Significance of a coronary artery with thrombolysis in myocardial infarction grade 2 flow "patency" (outcome in the thrombolysis and angioplasty in myocardial infarction trials). Thrombolysis and Angioplasty in Myocardial Infarction Study Group. 
  • Simultaneous ST-segment measurements using standard and monitoring-compatible torso limb lead placements at rest and during coronary occlusion. 
  • Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury. 
  • Single-vessel coronary artery stenosis: myocardial perfusion imaging with Gadomer-17 first-pass MR imaging in a swine model of comparison with gadopentetate dimeglumine. 
  • Slowed ST segment recovery despite early infarct artery patency in patients with Q waves at presentation with a first acute myocardial infarction. Implications of initial Q waves on myocyte reperfusion. 
  • Sodium nitroprusside, an endothelium-derived relaxing factor congener, increases platelet cyclic GMP levels and inhibits epinephrine-exacerbated in vivo platelet thrombus formation in stenosed canine coronary arteries. 
  • Spectrum of coronary artery disease in idiopathic hypertrophic subaortic stenosis. 
  • Spontaneous reperfusion in ST-elevation myocardial infarction: comparison of angiographic and electrocardiographic assessments. 
  • Stress proteins and cardiovascular disease. 
  • Studies of blood flow in aorta-to-coronary venous bypass grafts in man. 
  • Surgical management of congenital coronary artery fistula. 
  • Surgical repair of atrial septal defect in an 89-year-old man: progressive shunt due to concomitant aortic stenosis. 
  • Sympathetic influences on coronary and aortic flow responses to increasing heart rate. 
  • Symptomatic cardiac events following radiation therapy for left-sided breast cancer: possible association with radiation therapy-induced changes in regional perfusion. 
  • T2-weighted imaging to assess post-infarct myocardium at risk. 
  • TIMI frame count: a quantitative method of assessing coronary artery flow. 
  • Tc-99m sestamibi cardiac SPECT imaging during coronary artery occlusion in humans: comparison with dipyridamole stress studies. 
  • The coronary pressure-flow determinants left ventricular compliance in dogs. 
  • The deformational characteristics of the left ventricle in the conscious dog. 
  • The diastolic mechanical properties of the intact left ventricle. 
  • The direct incorporation of perfusion defect information to define ischemia and infarction in a finite element model of the left ventricle. 
  • The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging. 
  • The effect of altitude-induced hypoxia on regional myocardial blood flow. 
  • The effect of cardiac tamponade on coronary haemodynamics in the awake dog. 
  • The effect of chemical ablation of the endocardium on ventricular fibrillation threshold. 
  • The effect of coronary collateral circulation on experimental aorto-coronary bypass. 
  • The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses. 
  • The effect of nitroglycerin on response to tracheal intubation. Assessment by radionuclide angiography. 
  • The effects of atrial fibrillation on myocardial blood flow and energetics. 
  • The effects of atrial fibrillation on regional blood flow in the awake dog. 
  • The effects of dopamine on myocardial functional recovery after reversible ischemic injury. 
  • The electrophysiological effects of calcium channel blockade during standard hyperkalemic hypothermic cardioplegic arrest. 
  • The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial. 
  • The incidence and functional consequences of RT-associated cardiac perfusion defects. 
  • The influence of angiographically demonstrated coronary collaterals on the results of stress echocardiography. 
  • The initial electrocardiographic pattern in acute myocardial infarction: correlation with infarct size. 
  • The relationship between the myocardial kinetics of meperidine and its effect on myocardial contractility: model-independent analysis and optimal regional model. 
  • The relationship of transmural myocardial blood flow to midwall function. 
  • The safety of induced ventricular fibrillation during cardiopulmonary bypass in nonhypertrophied hearts. 
  • The use of tomographic myocardial perfusion scanning to evaluate an electrocardiographic salvage estimation method in patients with acute myocardial infarction: an AMISTAD substudy. Acute Myocardial Infarction Study Adenosine. 
  • The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs. 
  • Theophylline produces an adverse effect on myocardial lactate metabolism at a therapeutic serum concentration: an effect blocked by verapamil. 
  • Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts. 
  • Transesophageal echocardiographic evaluation of native aortic valve area: utility of the double-envelope technique. 
  • Transluminal catheter reperfusion: a new technique to reestablish blood flow after coronary occlusion during percutaneous transluminal coronary angioplasty. 
  • Transluminal intracoronary reperfusion catheter: a device to maintain coronary perfusion between failed coronary angioplasty and emergency coronary bypass surgery. 
  • Transmural myocardial blood flow in a canine model of coronary artery bridging. 
  • Transmyocardial laser revascularization for inoperable coronary artery disease. 
  • Trial of abciximab with and without low-dose reteplase for acute myocardial infarction. Strategies for Patency Enhancement in the Emergency Department (SPEED) Group. 
  • Type 2 myocardial infarction due to supply-demand mismatch. 
  • Unstable angina pectoris: National Cooperative Study Group to Compare Surgical and Medical Therapy. 
  • Use of an isolated heart model to test the utilization of substrates for inclusion in cardioplegic solutions. 
  • Use of the 12-lead ECG to detect myocardial reperfusion and salvage during acute myocardial infarction. 
  • Validation of 19F-magnetic resonance determination of myocardial blood volume. 
  • Validation of haemodialysis recirculation and access blood flow measured by thermodilution. 
  • Value of cardiovascular magnetic resonance stress perfusion testing for the detection of coronary artery disease in women. 
  • Vascular remodeling: mechanisms and implications. 
  • Ventricular arrhythmias during reperfusion. 
  • When is angina good? Preconditioning in acute myocardial infarction. 
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  Keywords of People

  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology
  • Turkington, Timothy Garvey, Associate Professor in Radiology, Radiology