Corticosterone

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  Subject Areas on Research

  • A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. 
  • A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding. 
  • Acute and chronic stress effects on open field activity in the rat: implications for a model of depression. 
  • Adipogenic and lipolytic effects of chronic glucocorticoid exposure. 
  • Adrenomedullary function in the neonatal rat: responses to acute hypoxia. 
  • Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. 
  • Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats. 
  • Alterations in the hypothalamic-pituitary-adrenal axis in a proposed animal model of depression with genetic muscarinic supersensitivity. 
  • Anterior and posterior, but not cheek, intraoral cannulation procedures elevate serum corticosterone levels in neonatal rat pups. 
  • Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. 
  • Behavioral manipulation of the diabetic phenotype in ob/ob mice. 
  • Blunted stress responses in delayed type hypersensitivity in mice lacking the neuronal isoform of nitric oxide synthase. 
  • CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. 
  • Central elevation of phenylethanolamine N-methyltransferase activity following stress. 
  • Central epinergic inhibition of corticosterone release in rat. 
  • Central immune overactivation in the presence of reduced plasma corticosterone contributes to swim stress-induced hyperalgesia. 
  • Characterization of the effect of cocaine on catecholamine uptake by pregnant myometrium. 
  • Chronic administration of U50,488H fails to produce hypothalamo-pituitary-adrenal axis tolerance in neonatal rats. 
  • Chronic cocaine administration sensitizes behavioral but not neuroendocrine responses. 
  • Cloned mice have an obese phenotype not transmitted to their offspring. 
  • Cocaine sensitization in periadolescent and adult rats. 
  • Comparative analysis of ACTH and corticosterone sampling methods in rats. 
  • Comparison of brainstem and adrenal circadian patterns of epinephrine synthesis. 
  • Comparison of plasma cortisol and corticosterone in the dexamethasone suppression test for melancholia. 
  • Corticosteroids in brain tissue. 
  • Corticosterone hypersecretion in preweanling rats exposed neonatally to trimethyltin. 
  • Corticotropin releasing factor stimulates growth hormone secretion in neonatal rats. 
  • D1 and D2 dopamine receptors stimulate hypothalamo-pituitary-adrenal activity in rats. 
  • Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice. 
  • Desacyl Ghrelin Decreases Anxiety-like Behavior in Male Mice. 
  • Development, maintenance, and function of the adrenal gland in early postnatal proopiomelanocortin-null mutant mice. 
  • Diet-induced type II diabetes in C57BL/6J mice. 
  • Differential anxiogenic, aversive, and locomotor effects of THC in adolescent and adult rats. 
  • Differential ontogeny of opioid, dopaminergic and serotonergic regulation of prolactin secretion. 
  • Differential sensitivity to dexamethasone suppression in an animal model of the DST. 
  • Early ethanol consumption predicts relapse-like behavior in adolescent male rats. 
  • Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. 
  • Effect of chronic methadone administration on neuroendocrine function in developing rats. 
  • Effect of ether stress on growth hormone during development in the neonatal rat. 
  • Effect of ovarian hormones and estrous cycle on stimulation of the hypothalamo-pituitary-adrenal axis by cocaine. 
  • Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats. 
  • Effects of cadmium ingestion and food restriction on energy metabolism and tissue metal concentrations in mallard ducks (Anas platyrhynchos). 
  • Effects of chronic mild stress on serum complement activity, saccharin preference, and corticosterone levels in Flinders lines of rats. 
  • Effects of fenbendazole administration on hematology, clinical chemistries and selected hormones in the white Pekin duck. 
  • Effects of immobilization restraint on Syrian golden hamsters. 
  • Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat. 
  • Endocrine effects of methadone in rats; acute effects in adults. 
  • Endocrine responses to mother-infant separation in developing rats. 
  • Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus. 
  • Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation. 
  • Extraction of corticosterone from cell homogenates and subcellular fractions of the rat adrenal cortex. III. ACTH-induced temporal subcellular redistributions of steroid precursors to corticosterone. 
  • Facilitation of cocaine kindling by glucocorticoids in rats. 
  • Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors. 
  • Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice. 
  • Glucocorticoid metabolism in proximal tubules modulates angiotensin II-induced electrolyte transport. 
  • Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection. 
  • Hepatic cyclic AMP generation and ornithine decarboxylase induction by glucagon and beta adrenergic agonists. 
  • Induction of immune activation by a novel immunomodulatory oligonucleotide without thymocyte apoptosis. 
  • Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents. 
  • Lack of annexin 1 results in an increase in corticotroph number in male but not female mice. 
  • Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy. 
  • Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: a putative role for corticotropin-releasing factor. 
  • Metabolic effects of voluntary wheel running in young and old Syrian golden hamsters. 
  • Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. 
  • Mouse handling limits the impact of stress on metabolic endpoints. 
  • Neural adaptation in imipramine-treated rats processed in forced swim test: assessment of time course, handling, rat strain and amine uptake. 
  • Neurotransmitter studies of neuroendocrine pathology in depression. 
  • Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. 
  • Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. 
  • Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. 
  • Olanzapine increases allopregnanolone in the rat cerebral cortex. 
  • Ontogenetic studies of tolerance development: effects of chronic morphine on the hypothalamic-pituitary-adrenal axis. 
  • Ontogeny of endocrine responses to methadone in rats. 
  • Ontogeny of mu- and kappa-opiate receptor control of the hypothalamo-pituitary-adrenal axis in rats. 
  • Plasma corticosterone in dexamethasone suppression test on depressed patients. 
  • Positive effects of tactile versus kinesthetic or vestibular stimulation on neuroendocrine and ODC activity in maternally-deprived rat pups. 
  • Preliminary studies of 6 beta-hydroxydexamethasone and its importance in the DST. 
  • Reduction of spinal PGE2 concentrations prevents swim stress-induced thermal hyperalgesia. 
  • Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus. 
  • Relative ontogeny of opioid and catecholaminergic regulation of thyrotropin secretion in the rat. 
  • Role of central glucagon-like peptide-1 in hypothalamo-pituitary-adrenocortical facilitation following chronic stress. 
  • Seasonality, sociality, and reproduction: Long-term stressors of ring-tailed lemurs (Lemur catta). 
  • Selective activation of mesoamygdaloid dopamine neurons by conditioned stress: attenuation by diazepam. 
  • Stressor-specific alterations in corticosterone and immune responses in mice. 
  • Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. 
  • The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat. 
  • The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. 
  • Vmat2 heterozygous mutant mice display a depressive-like phenotype. 
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  Keywords of People

  • Bradford, Daniel William, Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Social and Community Psychiatry
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology