Cotinine

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  Subject Areas on Research

  • 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. 
  • A whole blood gene expression-based signature for smoking status. 
  • An animal model of adolescent nicotine exposure: effects on gene expression and macromolecular constituents in rat brain regions. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD. 
  • Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. 
  • Does Extended Pre Quit Bupropion Aid in Extinguishing Smoking Behavior? 
  • EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence. 
  • Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms. 
  • Effect of Smoking Cessation on the Pharmacokinetics and Pharmacodynamics of Clopidogrel after PCI: The Smoking Cessation Paradox Study. 
  • Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. 
  • Exposure to environmental tobacco smoke during pregnancy in rats yields less effect on indices of brain cell number and size than does postnatal exposure. 
  • Human papillomavirus type 16 infection and squamous cell carcinoma of the head and neck in never-smokers: a matched pair analysis. 
  • Identifying the Best Questions for Rapid Screening of Secondhand Smoke Exposure Among Children. 
  • Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States. 
  • In vivo regulation of [3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs. 
  • Increases in impulsivity following smoking abstinence are related to baseline nicotine intake and boredom susceptibility. 
  • Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. 
  • Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice. 
  • Neighborhood Deprivation is Associated with Increased Risk of Prenatal Smoke Exposure. 
  • Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers. 
  • Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. 
  • Oral nicotine solution for smoking cessation: a pilot tolerability study. 
  • Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/Hyperactivity Disorder. 
  • Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers. 
  • Saliva nicotine as an index of plasma levels in nicotine skin patch users. 
  • Secondhand Smoke Exposure is Associated with Prevalent Heart Failure: Longitudinal Examination of the National Health and Nutrition Examination Survey. 
  • Secondhand smoke exposure is associated with abnormal P-wave axis. 
  • Secondhand smoke is associated with more frequent hospitalizations in children with sickle cell disease. 
  • Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. 
  • Serum cotinine concentration and wound complications in head and neck reconstruction. 
  • Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype. 
  • Smoking is associated with an age-related decline in exhaled nitric oxide. 
  • Smoking prevalence in early pregnancy: comparison of self-report and anonymous urine cotinine testing. 
  • Squamous cell carcinoma of the head and neck in never smoker-never drinkers: a descriptive epidemiologic study. 
  • Strain-specific altered nicotine metabolism in 3,3'-diindolylmethane (DIM) exposed mice. 
  • Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish. 
  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. 
  • The effect of laboratory-verified smoking on SARS-CoV-2 infection: results from the Troina sero-epidemiological survey. 
  • Tobacco Retail Outlets, Neighborhood Deprivation and the Risk of Prenatal Smoke Exposure. 
  • Tobacco exposure in adults and children with proteinuric glomerulopathies: a NEPTUNE cohort study. 
  • Tobacco exposure-related alterations in DNA methylation and gene expression in human monocytes: the Multi-Ethnic Study of Atherosclerosis (MESA). 
  • Transdermal nicotine replacement in pregnancy: maternal pharmacokinetics and fetal effects. 
  • Utility of biochemical verification of tobacco cessation in the Department of Veterans Affairs. 
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  Keywords of People

  • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society