Coumarins

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  Subject Areas on Research

  • Analysis of medaka cytochrome P450 3A homotropic and heterotropic cooperativity. 
  • Anti-AIDS agents 82: synthesis of seco-(3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives as novel anti-HIV agents. 
  • Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activity. 
  • Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs. 
  • Anti-AIDS agents. 42. Synthesis and anti-HIV activity of disubstituted (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone analogues. 
  • Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors. 
  • Flavonoids. 8. Synthesis and antifertility and estrogen receptor binding activities of coumarins and delta3-isoflavenes. 
  • Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. 
  • Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH. 
  • Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives. 
  • Molecular Damage Detection in an Elastomer Nanocomposite with a Coumarin Dimer Mechanophore. 
  • Optical sensor for the detection of caspase-9 activity in a single cell. 
  • Single-dose disulfiram does not inhibit CYP2A6 activity. 
  • Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity. 
  • Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop. 
  • Stereoselective synthesis of 2,6-trans-tetrahydropyran via primary diamine-catalyzed oxa-conjugate addition reaction of α,β-unsaturated ketone: total synthesis of psymberin. 
  • Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides. 
  • The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. 
  • The field ionization spectra of some natural coumarins. 
  • The pharmacogenetics of coumarin therapy. 
  • Tissue plasminogen activator and thrombin generation measurements using the Thrombinoscope. 
  • Trout liver slices for metabolism and toxicity studies. 
  • Use of common antiplatelet drugs for vascular diseases.