Critical Care

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  Subject Areas on Research

  • 30-Day risk-standardized mortality and readmission rates after ischemic stroke in critical access hospitals. 
  • A 39-year-old man with hip pain and respiratory failure. 
  • A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit. 
  • A Comparative Analysis of Pulmonary and Critical Care Medicine Guideline Development Methodologies. 
  • A comparison of 3% hypertonic saline and mannitol for brain relaxation during elective supratentorial brain tumor surgery. 
  • A few of our favorite unconfirmed ideas. 
  • A multi-institutional high-fidelity simulation "boot camp" orientation and training program for first year pediatric critical care fellows. 
  • A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation. 
  • A new forum for health services research in critical care medicine. 
  • A new surgical monitoring and resuscitation cart. 
  • A noninvasive hemoglobin monitor in the pediatric intensive care unit. 
  • A randomized evaluation of bispectral index-augmented sedation assessment in neurological patients. 
  • A randomized, open-label study of the safety and tolerability of fospropofol for patients requiring intubation and mechanical ventilation in the intensive care unit. 
  • A reliable and cost-effective neonatal aminoglycoside administration system. 
  • ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). 
  • ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). 
  • ATS Core Curriculum 2014: Part II. Adult critical care medicine. 
  • Accuracy of references in three critical care nursing journals. 
  • Acquired thrombotic risk factors in the critical care setting. 
  • Acute decompensated heart failure patients admitted to critical care units: insights from ASCEND-HF. 
  • Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance. 
  • Acute pancreatitis and fulminant hepatic failure. 
  • Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care. 
  • Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study. 
  • Altruism, incentives, and organ donation: attitudes of the transplant community. 
  • Alveolar-arterial oxygen gradients before extracorporeal life support for severe pediatric respiratory failure: improved outcome for extracorporeal life support-managed patients? 
  • American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock. 
  • An Official American Thoracic Society/European Respiratory Society Workshop Report: Evaluation of Respiratory Mechanics and Function in the Pediatric and Neonatal Intensive Care Units. 
  • An analysis of time and staff utilization for open versus percutaneous tracheostomies. 
  • An official American Thoracic Society statement: Treatment of fungal infections in adult pulmonary and critical care patients. 
  • Analgesia in the surgical intensive care unit. 
  • Are pediatric critical care medicine fellowships teaching and evaluating communication and professionalism? 
  • Are we creating survivors…or victims in critical care? Delivering targeted nutrition to improve outcomes. 
  • Assessing and improving safety climate in a large cohort of intensive care units. 
  • Assessing the comparative value of sedatives in the intensive care unit. 
  • Assessment of out-of-hospital resuscitation. 
  • Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants With Hypoplastic Left Heart Syndrome Who Underwent Stage I Palliation (from the Single Ventricle Reconstruction Trial). 
  • Attitudes and knowledge of nurses regarding organ procurement. 
  • Benzodiazepines in the intensive care unit. 
  • Biases in the measurement of arterial pressure. 
  • Brain resuscitation in the drowning victim. 
  • Brainstem dysfunction as a predictor of death in the nonneurologically injured. 
  • COCATS 4 Task Force 13: Training in Critical Care Cardiology. 
  • Cardiology and the critical care crisis: a perspective. 
  • Case 6-2011: Aortic valve replacement in a patient with aortic stenosis, dilated cardiomyopathy, and renal dysfunction. 
  • Case study: heart transplantation--increased incidence of acute rejection in female recipients. 
  • Cerebral aneurysms: mechanisms of injury and critical care interventions. 
  • Changes in Payment Regulation and Acute Care Use for Total Hip Replacement: Trends in Length of Stay, Costs, and Discharge, 1997-2012. 
  • Changing physician behavior: a review of patient safety in critical care medicine. 
  • Choice of fluid in acute illness: what should be given? An international consensus. 
  • Chronic critical illness. 
  • Chronic critical illness: the growing challenge to health care. 
  • Cimetidine versus antacids in the prevention of stress erosions in critically ill patients. 
  • Clinical course and outcome predictors of critically ill infants with complete DiGeorge anomaly following thymus transplantation. 
  • Clinical practice guidelines for the maintenance of patient physical safety in the intensive care unit: use of restraining therapies--American College of Critical Care Medicine Task Force 2001-2002. 
  • Clinical review: Optimizing enteral nutrition for critically ill patients--a simple data-driven formula. 
  • Cognitive and physical rehabilitation of intensive care unit survivors: results of the RETURN randomized controlled pilot investigation. 
  • Comparison of Pediatric Severe Sepsis Managed in U.S. and European ICUs. 
  • Comparison of the response of saline tonometry and an automated gas tonometry device to a change in CO2. 
  • Consensus statement on continuous EEG in critically ill adults and children, part I: indications. 
  • Consensus statement on continuous EEG in critically ill adults and children, part II: personnel, technical specifications, and clinical practice. 
  • Consideration of adult critical care training for emergency physicians. 
  • Continuous High-Frequency Oscillation Therapy in Invasively Ventilated Pediatric Subjects in the Critical Care Setting. 
  • Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study. 
  • Continuous arteriovenous hemodialysis: effect of dialyzer geometry. 
  • Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. 
  • Conventional and Unconventional Lifesaving Therapies in an Adolescent With Amlodipine Ingestion. 
  • Converting i.v. nitroglycerin therapy to nitroglycerin ointment therapy: a comparison of two methods. 
  • Coping as a Multifaceted Construct: Associations With Psychological Outcomes Among Family Members of Mechanical Ventilation Survivors. 
  • Cost analysis of aprotinin for coronary artery bypass patients: analysis of the randomized trials. 
  • Counterpoint: Are the best patient outcomes achieved when ICU bundles are rigorously adhered to? No. 
  • Critical Care Air Transport Team severe traumatic brain injury short-term outcomes during flight for Operation Iraqi Freedom/Operation Enduring Freedom. 
  • Critical care aspects of lung transplantation. 
  • Critical care cardiology research: a call to action. 
  • Critical care nursing education at the baccalaureate level. 
  • Critical care nursing education at the baccalaureate level: study of employment and job satisfaction. 
  • Critical care perspective on immunotherapy in lung transplantation. 
  • Critical research on biomarkers: what's new? 
  • Critical thinking, critical practice. 
  • Current teaching and evaluation methods in critical care medicine: has the Accreditation Council for Graduate Medical Education affected how we practice and teach in the intensive care unit? 
  • Defining the Role of Dexmedetomidine in the Prevention of Delirium in the Intensive Care Unit. 
  • Delirium monitoring and patient outcomes in a general intensive care unit. 
  • Demand-flow airway pressure release ventilation as a partial ventilatory support mode: comparison with synchronized intermittent mandatory ventilation and pressure support ventilation. 
  • Developing a Research Agenda for Integrating Palliative Care into Critical Care and Pulmonary Practice To Improve Patient and Family Outcomes. 
  • Developing a Tool to Assess Placement of Central Venous Catheters in Pediatrics Patients. 
  • Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research. 
  • Development and Validation of a Mortality Prediction Model for Patients Receiving 14 Days of Mechanical Ventilation. 
  • Development and preliminary assessment of a critical care ultrasound course in an adult pulmonary and critical care fellowship program. 
  • Development of a web-based, specialty specific portfolio. 
  • Dexmedetomidine for the treatment of alcohol withdrawal syndrome: rationale and current status of research. 
  • Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. 
  • Discrepant attitudes about teamwork among critical care nurses and physicians. 
  • Economic Outcomes of Extracorporeal Membrane Oxygenation With and Without Ambulation as a Bridge to Lung Transplantation. 
  • Effective cohorting and "superisolation" in a single intensive care unit in response to an outbreak of diverse multi-drug-resistant organisms. 
  • Effectiveness of a critical care nursing course: preparing students for practice in critical care. 
  • Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial. 
  • Elevation of pulmonary artery pressure as a sign of pulmonary barotrauma (pneumothorax). 
  • End-stage renal disease and intensive care unit prognosis: are current tools good enough? 
  • Engaging Survivors of Critical Illness in Health Care Assessment and Policy Development. Ethical and Practical Complexities. 
  • Engaging nurses in patient safety. 
  • Engaging research partners to advance clinical inquiry. 
  • Enterovirus D68 Infection in an Adult. 
  • Epidemiology and Characteristics of Neurosurgical Conditions at Mbarara Regional Referral Hospital. 
  • Epidemiology, pathophysiology and clinical presentation of gram-negative sepsis. 
  • Evaluation and management of the atrial fibrillation patient: a report from the Society of Cardiovascular Patient Care. 
  • Evaluation of a life support module used for air transport of critically ill infants. 
  • Evaluation of an evidence-based, nurse-driven checklist to prevent hospital-acquired catheter-associated urinary tract infections in intensive care units. 
  • Evaluation of the effect of the modified early warning system on the nurse-led activation of the rapid response system. 
  • Evidence-based assessments in the ventilator discontinuation process. 
  • Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association. 
  • Exploring the impact of augmenting sedation assessment with physiologic monitors. 
  • Facilitating palliative care referrals in the intensive care unit: a pilot project. 
  • Family Presence During Pediatric Tracheal Intubations. 
  • Finding the optimal combination therapy for the treatment of newly diagnosed AML in older patients unfit for intensive therapy. 
  • From Coronary Care Units to Cardiac Intensive Care Units: Recommendations for Organizational, Staffing, and Educational Transformation. 
  • Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. 
  • Glutamine Supplementation in Parenteral Nutrition and Intensive Care Unit Patients: Are We Throwing the Baby Out With the Bathwater? 
  • Health Care Professionals' Responses to Religious or Spiritual Statements by Surrogate Decision Makers During Goals-of-Care Discussions. 
  • Healthcare Resource Availability, Quality of Care, and Acute Ischemic Stroke Outcomes. 
  • Heart sound simulation: how useful for critical care nurses? 
  • Heat loss prevention for preterm infants in the delivery room. 
  • Heliox administration in the pediatric intensive care unit: an evidence-based review. 
  • Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial. 
  • Hemodynamic monitoring in critically ill patients. 
  • Hemodynamic monitoring in the critically ill patient: overview of symposium. 
  • High-frequency oscillatory ventilation in pediatric respiratory failure: a multicenter experience. 
  • High-frequency ventilation. 
  • How to assess critical thinking in clinical practice. 
  • Hyperammonemia in the ICU. 
  • Impact of restarting home neuropsychiatric medications on sedation outcomes in medical intensive care unit patients. 
  • Implementation of antibiotic rotation protocol improves antibiotic susceptibility profile in a surgical intensive care unit. 
  • Improvements in pulmonary and general critical care reduces mortality following ventilator-associated pneumonia. 
  • In reply. 
  • Incidence and Risk Factors for Intensive Care Unit-related Post-traumatic Stress Disorder in Veterans and Civilians. 
  • Incorporating Interprofessional Evidenced-Based Sepsis Simulation Education for Certified Nursing Assistants (CNAs) and Licensed Care Providers Within Long-term Care Settings for Process and Quality Improvement. 
  • Indications for tracheotomy in the pediatric intensive care unit population: a pilot study. 
  • Infections caused by multidrug resistant organisms are not associated with overall, all-cause mortality in the surgical intensive care unit: the 20,000 foot view. 
  • Infective Endocarditis. 
  • Insights in pediatric ventilation: timing of intubation, ventilatory strategies, and weaning. 
  • Intensification of Medication Therapy for Cardiorenal Syndrome in Acute Decompensated Heart Failure. 
  • Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes. 
  • Intensive management and treatment of severe Guillain-Barré syndrome. 
  • Intensive management of severe head injury. 
  • Interdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis. 
  • Intravenous fluids in sepsis: what to use and what to avoid. 
  • Intravenous ziprasidone for treatment of delirium in the intensive care unit. 
  • Introduction to "A Compendium of Strategies To Prevent Healthcare-Associated Infections in Acute Care Hospitals: 2014 updates". 
  • Invasive Mechanical Ventilation and Mortality in Pediatric Hematopoietic Stem Cell Transplantation: A Multicenter Study. 
  • Invited commentary. 
  • Job satisfaction among critical care preceptors. 
  • Management of cardiogenic shock. 
  • Managing new oral anticoagulants in the perioperative and intensive care unit setting. 
  • Measurement of quality and assurance of safety in the critically ill. 
  • Medical and economic implications of prolonged mechanical ventilation and expedited post-acute care. 
  • Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation. 
  • Moderate-to-Severe Traumatic Brain Injury in Children: Complications and Rehabilitation Strategies. 
  • Muscle mass and physical recovery in ICU: innovations for targeting of nutrition and exercise. 
  • Near-infrared spectroscopy. Clinical applications. 
  • Neonatal and pediatric respiratory care: what does the future hold? 
  • Neural Control of Inflammation: Implications for Perioperative and Critical Care. 
  • Neurocritical care monitoring correlates with neuropathology in a swine model of pediatric traumatic brain injury. 
  • Neurologic intensive care unit monitoring. 
  • New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance. 
  • Not by the books. 
  • Nutritional pharmacology in surgery and critical care: 'you must unlearn what you have learned'. 
  • Nutritional support in the critically ill elderly patient. 
  • Operationalizing the Measuring What Matters Spirituality Quality Metric in a Population of Hospitalized, Critically Ill Patients and Their Family Members. 
  • Organ donation and treatment of the multi-organ donor. 
  • Orthopaedic trauma for the general orthopaedist: avoiding problems and pitfalls in treatment. 
  • Our favorite unproven ideas for future critical care. 
  • Parenteral glutamine supplementation in critical illness: a systematic review. 
  • Pediatric acute respiratory failure: areas of debate in the pediatric critical care setting. 
  • Pediatric postoperative cardiac care. 
  • Performance of Consultative Palliative Care Model in Achieving Quality Metrics in the ICU 
  • Performance of Consultative Palliative Care Model in Achieving Quality Metrics in the ICU. 
  • Performance-enhancing sports supplements: role in critical care. 
  • Perioperative anesthetic management for Cesarean section of a parturient with gestational diabetes insipidus. 
  • Pharmacological considerations in human immunodeficiency virus-infected adults in the intensive care unit. 
  • Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning. 
  • Precision diagnosis: a view of the clinical decision support systems (CDSS) landscape through the lens of critical care. 
  • Predicting proper endotracheal tube placement in underexposed radiographs: tangent line of the aortic arch. 
  • Predictors of extraventricular drain-associated bacterial ventriculitis. 
  • Professionalism and Communication Education in Pediatric Critical Care Medicine: The Learner Perspective. 
  • Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit. 
  • Project CAPE: a high-fidelity, in situ simulation program to increase Critical Access Hospital Emergency Department provider comfort with seriously ill pediatric patients. 
  • Pulmonary embolism complicating barbiturate overdose. 
  • Pulse oximetry in critical care scoring systems. 
  • Quiet time: a nursing intervention to promote sleep in neurocritical care units. 
  • Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial. 
  • Racial differences in hospice use and patterns of care after enrollment in hospice among Medicare beneficiaries with heart failure. 
  • Racial variation in initial stroke severity. 
  • Radiographic and Clinical Predictors of Cardiac Dysfunction Following Isolated Traumatic Brain Injury. 
  • Radiographic recognition of pneumothorax in the intensive care unit. 
  • Real-time application of continuous 12-lead ST-segment monitoring: 3 case studies. 
  • Rebuttal from Dr Marik et al. 
  • Reforming nursing education for future practice. 
  • Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000-2007. 
  • Respiratory controversies in the critical care setting. Conference summary. 
  • Respiratory controversies in the critical care setting. Part I. 
  • Respiratory therapies in the critical care setting. Should every mechanically ventilated patient be monitored with capnography from intubation to extubation? 
  • Risk factors for nosocomial pneumonia: comparing adult critical-care populations. 
  • Role of L-glutamine in critical illness: new insights. 
  • Satisfaction with a new model of professional practice in critical care. 
  • Searching for "the dying point:" providers' experiences with palliative care in pediatric acute care. 
  • Sepsis-induced disseminated intravascular coagulation, symmetrical peripheral gangrene, and amputations. 
  • Setting the vision: applied patient-reported outcomes and smart, connected digital healthcare systems to improve patient-centered outcomes prediction in critical illness. 
  • Simulation for Skills-based Education in Pulmonary and Critical Care Medicine. 
  • Spiritual Care Providers and Goals-of-Care Discussions--Reply. 
  • Spirituality, Palliative Care, and the Intensive Care Unit. A New Approach. 
  • Standard subcutaneous dosing of unfractionated heparin for venous thromboembolism prophylaxis in surgical ICU patients leads to subtherapeutic factor Xa inhibition. 
  • Statins and delirium during critical illness: a multicenter, prospective cohort study. 
  • Strategies to prevent central line-associated bloodstream infections in acute care hospitals. 
  • Strategies to prevent clostridium difficile infections in acute care hospitals. 
  • Strategies to prevent surgical site infections in acute care hospitals. 
  • Strategies to prevent ventilator-associated pneumonia in acute care hospitals. 
  • Stress reduction for pediatric intensive care nurses. 
  • Structured Documentation of Home Ventilator Settings in Children: A Quality Improvement Project. 
  • Students' knowledge and perceptions of critical care nursing. 
  • Study of educational experiences, support, and job satisfaction among critical care nurse preceptors. 
  • Survey of anesthesiologists practicing in American neurointensive care units as neurointensivists. 
  • Survey of in-house coverage by pediatric intensivists: characterization of 24/7 in-hospital pediatric critical care faculty coverage*. 
  • Surviving critical illness: acute respiratory distress syndrome as experienced by patients and their caregivers. 
  • Symptomatic Avascular Necrosis: An Understudied Risk Factor for Acute Care Utilization by Patients with SCD. 
  • Take heart: a one-on-one peer-based strategy to improve acute coronary syndrome patient care. 
  • Temperature monitoring. 
  • The "other" intensive care unit. 
  • The Accreditation Council for Graduate Medical Education proposed work hour regulations. 
  • The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States. 
  • The Genesis, Maturation, and Future of Critical Care Cardiology. 
  • The ICU chest film. Cardiopulmonary monitoring and assist devices. 
  • The Voice of Surrogate Decision-Makers. Family Responses to Prognostic Information in Chronic Critical Illness. 
  • The Worldwide End-of-Life Practice for Patients in Intensive Care Units Study: Adding Africa. 
  • The authors reply. 
  • The course of psychological distress following threatened and actual conjugal bereavement. 
  • The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. 
  • The evolution of nutrition in critical care: how much, how soon? 
  • The first step toward data reuse: disambiguating concept representation of the locally developed ICU nursing flowsheets. 
  • The glutamine story: where are we now? 
  • The impact of bispectral index monitoring on rates of propofol administration. 
  • The limited reliability of the Ramsay scale. 
  • The structure of critical care transfer networks. 
  • The ventilator discontinuation process: an expanding evidence base. 
  • Therapeutic Alliance between the Caregivers of Critical Illness Survivors and Intensive Care Unit Clinicians. 
  • Third universal definition of myocardial infarction. 
  • To stop or not to stop: how much support should be provided to mechanically ventilated pediatric bone marrow and stem cell transplant patients? 
  • Too much of a good thing? Tracing the history of the propofol infusion syndrome. 
  • Toward Designing Information Display to Support Critical Care. A Qualitative Contextual Evaluation and Visioning Effort. 
  • Toward solving the sedation-assessment conundrum: bi-spectral index monitoring and sedation interruption. 
  • Tracheobronchial trauma associated with airway management in neonates. 
  • Transfusion in Ischemic Heart Disease: Correlation, Confounding, and Confusion. 
  • Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: a randomized controlled trial. 
  • Using ClinicalTrials.gov to understand the state of clinical research in pulmonary, critical care, and sleep medicine. 
  • Utilization of Quantitative EEG Trends for Critical Care Continuous EEG Monitoring: A Survey of Neurophysiologists. 
  • Ventilatory management in critical neurologic illness. 
  • What is the ideal crystalloid? 
  • Working with the family of a critically ill child. 
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  Keywords of People

  • Bettger, Janet Prvu, Associate Professor of Orthopaedic Surgery, School of Nursing
  • Chudgar, Saumil Mahendra, Associate Professor of Medicine, Medicine, General Internal Medicine
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia
  • Jones, Derek, Analyst, IT, Office of Research Informatics
  • Joshi, Sangeeta Prabhakar, Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Krishnamoorthy, Vijay, Assistant Professor of Anesthesiology, Anesthesiology, Critical Care Medicine
  • Kussin, Peter Samuel, Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Lee, Walter T, Associate Professor of Surgery, Radiation Oncology
  • Levy, Jerrold Henry, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • McConnell, Eleanor Schildwachter, Associate Professor in the School of Nursing, with tenure, School of Nursing
  • Moody, James, Professor in the Department of Sociology, Social Science Research Institute
  • Moretti, Eugene William, Professor of Anesthesiology, School of Nursing
  • Olson, Steven Arthur, Professor of Orthopaedic Surgery, Orthopaedics
  • Turner, David Ashley, Associate Professor of Pediatrics, Pediatrics, Critical Care Medicine
  • Wischmeyer, Paul Edmund, Professor of Anesthesiology, Anesthesiology, Critical Care Medicine