Cross Reactions

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  Subject Areas on Research

  • A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques. 
  • A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein. 
  • A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. 
  • A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. 
  • A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design. 
  • A retrospective analysis of cross-reacting cetuximab IgE antibody and its association with severe infusion reactions. 
  • A soluble inhibitor of T lymphocyte function induced by HIV-1 infection of CD4+ T cells: characterization of a cellular protein and its relationship to p15E. 
  • Absence of neutralizing antibodies against influenza A/H5N1 virus among children in Kamphaeng Phet, Thailand. 
  • Algorithm for the early diagnosis and treatment of patients with cross reactive immunologic material-negative classic infantile pompe disease: a step towards improving the efficacy of ERT. 
  • Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals. 
  • An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates. 
  • An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains. 
  • An isoform of ankyrin is localized at nodes of Ranvier in myelinated axons of central and peripheral nerves. 
  • Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates. 
  • Ancestral and consensus envelope immunogens for HIV-1 subtype C. 
  • Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. 
  • Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors. 
  • Antibody to native human immunodeficiency virus type 1 envelope glycoproteins induced by IIIB and MN recombinant gp120 vaccines. The NIAID AIDS Vaccine Evaluation Group. 
  • Antibody-dependent enhancement of SIV infection: further characterization and cross reactivity between macaque and sooty mangabey isolates. 
  • Antibody-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes. 
  • Antigen-binding repertoire and Ig H chain gene usage among B cell hybridomas from normal and autoimmune mice. 
  • Antigenic difference between viral strains causing classical and mild types of epidemic hemorrhagic fever with renal syndrome in China. 
  • Antigenic relationships between murine, feline and primate RNA tumor viruses and membrane antigens of human leukemic cells. 
  • Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1. 
  • Antigens shared by rat schwannomas, neuroblastomas, and a testicular interstitial cell carcinoma. 
  • Antiinflammatory proteins associated with human and murine neoplasms. 
  • Assembly of a chemically synthesized peptide of Escherichia coli type 1 fimbriae into fimbria-like antigenic structures. 
  • Atypical immunologic response in a patient with CRIM-negative Pompe disease. 
  • Bactericidal antibody after colonization with Neisseria meningitidis. 
  • Biochemical and immunological properties of dog brain isorenin. 
  • Brain ankyrin. Purification of a 72,000 Mr spectrin-binding domain. 
  • Broadly Neutralizing Antibody Responses in a Subset of HIV-1-Infected Individuals in Chennai, India. 
  • CD8 CTL responses in vaccines: emerging patterns of HLA restriction and epitope recognition. 
  • CRIM-negative infantile Pompe disease: characterization of immune responses in patients treated with ERT monotherapy. 
  • Ca2+/calmodulin-dependent protein kinase II from hen brain. Purification and characterization. 
  • Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. 
  • Characterization and idiotypic analysis of an anti-RNP monoclonal antibody. 
  • Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. 
  • Characterization of antibodies to canine renal renin. Studies of interspecies homology of renin using antibodies as probe. 
  • Characterization of chimpanzee leukocyte alloantisera. 
  • Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L. 
  • Characterization of prostate-tissue-directed monoclonal antibody, alpha-Pro 13. 
  • Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. II. Response in C57BL/6 mice. 
  • Chromosome mapping of human cell surface molecules: monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11. 
  • Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers. 
  • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. 
  • Cold agglutinins and cold-agglutinin disease. 
  • Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10. 
  • Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques. 
  • Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. 
  • Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity. 
  • Cross-clade human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte responses in HIV-infected Zambians. 
  • Cross-linking of neurofilament proteins of rat spinal cord in vivo after administration of 2,5-hexanedione. 
  • Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state. 
  • Cross-reaction to maprotiline. 
  • Cross-reactions of virally and chemically induced mouse sarcomas: surface expression of a common viral antigen. 
  • Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies. 
  • Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. 
  • Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. 
  • Cross-reactive idiotypes in the sera of patients with bullous pemphigoid express anti-basement-membrane-zone activity. 
  • Cross-reactive immunologic material status affects treatment outcomes in Pompe disease infants. 
  • Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins. 
  • Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection. 
  • Cross-reactivity of HIV vaccine responses and the microbiome. 
  • Cross-reactivity of primate alloantigens: absorption of anti-HL-A reactivity from human alloantisera by chimpanzee lymphocytes. 
  • Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers. 
  • Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. 
  • Cytokeratin 12 in human ocular surface epithelia is the antigen reactive with a commercial anti-Galpha q antibody. 
  • Cytotoxicity reactions of chimpanzee antisera with human lymphocyte donors phenotyped or genotyped for HL-A. 
  • Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. 
  • Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor. 
  • Detection of cross-reactive idiotypes in the serum of patients with bullous pemphigoid. 
  • Detection of oncornavirus antigenic activity in human urothelial tissues. 
  • Development of a monoclonal antibody specific for serotype 3 rotavirus strains. 
  • Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals. 
  • Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women. 
  • Diversity considerations in HIV-1 vaccine selection. 
  • Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade. 
  • Estrogen induction of plasma vitellogenin in the cockerel: studies with a phosvitin antibody. 
  • Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. 
  • Expression of apolipoprotein E during nerve degeneration and regeneration. 
  • Expression of cross-reactive idiotypes at the basement membrane zone in patients with bullous pemphigoid. 
  • Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001. 
  • GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates. 
  • Gastrin/cholecystokinin-like immunoreactive peptides in the Dungeness crab, Cancer magister (Dana): immunochemical and biological characterization. 
  • Generation of human IgG, IgA, and IgM anti-melanoma monoclonal antibodies utilizing lymphocytes of an actively immunized melanoma patient. 
  • Generation of species cross-reactive aptamers using "toggle" SELEX. 
  • Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies. 
  • H-2K-, H-21- and H-2D-restricted hybridoma contact sensitivity effector cells. 
  • H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. 
  • HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques. 
  • HIV vaccine rationale, design and testing. 
  • HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism. 
  • HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. 
  • HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. 
  • HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria. 
  • HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies. 
  • Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. 
  • Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses. 
  • High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass. 
  • High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination. 
  • Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus. 
  • Human T-cell leukemia/lymphoma virus: studies of host-virus interaction. 
  • Human epidermal plasminogen activator. Characterization, localization, and modulation. 
  • Human erythrocyte myosin: identification and purification. 
  • Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection. 
  • Human melanoma and leukemia associated antigens difined by nonhuman primate antisera. 
  • Human sulfite oxidase deficiency. Characterization of the molecular defect in a multicomponent system. 
  • IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria. 
  • Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody. 
  • Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120. 
  • Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models. 
  • Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. 
  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. 
  • Idiotypes, anti-idiotypes, and autoimmunity. 
  • Idiotypic cross-reaction between MRL autoantibodies and a BALB/c myeloma. 
  • Idiotypic cross-reaction between MRL monoclonal autoantibodies with different antigen specificity. 
  • IgG antinuclear antibodies with cross-reactive rheumatoid factor activity. 
  • IgG binding of monoclonal anti-nuclear antibodies from MRL-lpr/lpr mice. 
  • Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization. 
  • Immunoblot analyses of Candida albicans-associated antigens and antibodies in human sera. 
  • Immunochemical properties of anti-DNA antibodies in the sera of patients with Escherichia coli bacteremia. 
  • Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians. 
  • Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes. 
  • Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on surfaces of virus-producing murine and other mammalian species cell lines. 
  • Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140. 
  • Immunological comparison of lipoxygenase isozymes-1 and -2 with soybean seedling lipoxygenases. 
  • Immunological correspondence between arthropod hemocyanin subunits. II. Xiphosuran (Limulus) and spider (Eurypelma, Cupiennius) hemocyanin. 
  • Immunotherapy for malignant melanoma with a tumor cell vaccine. 
  • In vitro RNA selection of an autoimmune epitope on stem-loop II of U1 RNA. 
  • In vitro selection of RNA epitopes using autoimmune patient serum. 
  • Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice. 
  • Increased brain-type creatine phosphokinase in marathon runners. 
  • Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Induction of immune responses with anti-idiotypic antibodies: implications for the induction of protective immunity. 
  • Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques. 
  • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA. 
  • Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations. 
  • Interspecies reactivity of type C and D retrovirus p 15E and p 15C proteins. 
  • Isolation of novel EGFR-specific VHH domains. 
  • Lack of specificity of cyclosporine immunoassays. Results of a College of American Pathologists Study. 
  • Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection. 
  • Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. 
  • Microtubule-associated protein 2, a microtubule-associated protein from brain, is immunologically related to the alpha subunit of erythrocyte spectrin. 
  • Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications. 
  • Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors. 
  • Monoclonal antibodies reactive with human T cell lymphotropic virusI (HTLVI) p19 internal core protein: cross-reactivity with normal tissues and differential reactivity with HTLV types I and II. 
  • Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains. 
  • Multiple assay characterization of murine monoclonal antimelanoma antibodies. 
  • Multiple-analyte fluoroimmunoassay using an integrated optical waveguide sensor. 
  • Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens. 
  • Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. 
  • Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus. 
  • Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. 
  • New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency. 
  • Normal chicken cells (chf-) express a surface antigen which cross-reacts with determinants of the major envelope glycoprotein (gp85) of avian myeloblastosis virus. 
  • Novel Monoclonal Antibodies for Studies of Human and Rhesus Macaque Secretory Component and Human J-Chain. 
  • Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies. 
  • Penicillin allergy: A practical guide for clinicians. 
  • Pharmacokinetics of radiolabeled monoclonal antibody B6.2 in patients with metastatic breast cancer. 
  • Phenytoin overview--metabolite interference in some immunoassays could be clinically important: results of a College of American Pathologists study. 
  • Polypeptides of mammalian oncornaviruses. II Characterization of murine leukemia virus polypeptide (p 15) bearing interspecies reactivity. 
  • Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA. 
  • Potential pathogenicity of deglycosylated IgG cross reactive with streptokinase and fibronectin in the serum of patients with rheumatoid arthritis. 
  • Predicting cross-reactive immunological material (CRIM) status in Pompe disease using GAA mutations: lessons learned from 10 years of clinical laboratory testing experience. 
  • Predicting tuberculosis: does the IGRA tell the tale? 
  • Profiles of neutralizing antibody response in chronically human immunodeficiency virus type 1 clade B'-infected former plasma donors from China naive to antiretroviral therapy. 
  • Prospective study of avian influenza virus infections among rural Thai villagers. 
  • Pseudotyped viruses permit rapid detection of neutralizing antibodies in human and equine serum against Venezuelan equine encephalitis virus. 
  • Pulsing of dendritic cells with cell lysates from either B16 melanoma or MCA-106 fibrosarcoma yields equally effective vaccines against B16 tumors in mice. 
  • Purification and identification of two serine class proteinases from dog mast biochemically and immunologically similar to human proteinases tryptase and chymase. 
  • Purification and properties of sulfite oxidase from human liver. 
  • Purification and serological characterization of the major envelope glycoprotein from AKR murine leukemia virus and its reactivity with autogenous immune sera from mice. 
  • Q Fever, Scrub Typhus, and Rickettsial Diseases in Children, Kenya, 2011-2012. 
  • RNA surfaces as functional mimetics of proteins. 
  • Rapid bacterial antigen detection is not clinically useful. 
  • Rat sulfite oxidase antibodies cross-react with two gene family-related proteins: albumin and vitamin D-binding protein. 
  • Reactions of human HL-A sera with orangutan and gorilla lymphocytes. 
  • Rearrangement and expression of the human psi C lambda 6 gene segment results in a surface Ig receptor with a truncated light chain constant region. 
  • Relationships between membrane antigens of human leukemic cells and oncogenic RNA virus structural components. 
  • Reverse transcription-PCR-enzyme-linked immunosorbent assay for rapid detection and differentiation of alphavirus infections. 
  • Safety and Immunogenicity of a Single Low Dose or High Dose of Clade 2 Influenza A(H5N1) Inactivated Vaccine in Adults Previously Primed With Clade 1 Influenza A(H5N1) Vaccine. 
  • Selenium-dependent glutathione peroxidase protein and activity: immunological investigations on cellular and plasma enzymes. 
  • Sequential adsorption analysis of antibodies to neuroectodermal cells by an indirect quantitative method. 
  • Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. 
  • Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity. 
  • Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant. 
  • Specificity of autoantibodies for recombinant 60-kd and 52-kd Ro autoantigens. 
  • Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine. 
  • Specificity, cross-reactivity, and affinity of 125I-labeled antiglioma antibodies for monolayers of cultured glioma cells. 
  • Stevens-Johnson syndrome induced by the cross-reactivity between teicoplanin and vancomycin. 
  • Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein. 
  • Studies on the biosynthesis of laminin by murine parietal endoderm cells. 
  • Synapsin I is a spectrin-binding protein immunologically related to erythrocyte protein 4.1. 
  • Temporal correlation of antibody responses to different epitopes of the human La autoantigen. 
  • The ability of certain SIV vaccines to provoke reactions against normal cells. 
  • The antibody response in Lyme disease. 
  • The antigenic properties of bacterial DNA in normal and aberrant immunity. 
  • The binding of sera of patients with SLE to bacterial and mammalian DNA. 
  • The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells. 
  • The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies. 
  • The responses of atrial natriuretic factor concentrations to acute volume changes in conscious rats. 
  • The unique identity of rat hepatoma phenylalanine hydroxylase 
  • Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism. 
  • Toward an HIV type 1 vaccine that generates potent, broadly cross-reactive neutralizing antibodies. 
  • Viral glycoprotein synthesis studies in an established line of Japanese quail embryo cells infected with the Bryan high-titer strain of Rous sarcoma virus. 
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  Keywords of People

  • Ferrari, Guido, Associate Professor of Surgery, Molecular Genetics and Microbiology
  • McClain, Micah Thomas, Associate Professor of Medicine, Medicine, Infectious Diseases
  • Patz Jr., Edward F., James and Alice Chen Professor of Radiology, Pathology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology