Cryptococcus

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  Subject Areas on Research

  • 5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus. 
  • A High-Resolution Map of Meiotic Recombination in Cryptococcus deneoformans Demonstrates Decreased Recombination in Unisexual Reproduction. 
  • A chronological history of the International Conference on Cryptococcus and Cryptococcosis (ICCC), an invaluable forum for growth of the cryptococcal research field and clinical practice. 
  • A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients. 
  • Binding of purified and radioiodinated capsular polysaccharides from Cryptococcus neoformans serotype A strains to capsule-free mutants. 
  • Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings. 
  • Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions. 
  • Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. 
  • Clonality and recombination in genetically differentiated subgroups of Cryptococcus gattii. 
  • Combined activity of amphotericin B and 5-fluorocytosine against Cryptococcus neoformans in vitro and in vivo in mice. 
  • Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. 
  • Cryptococcal Antigen in Serum and Cerebrospinal Fluid for Detecting Cryptococcal Meningitis in Adults Living With Human Immunodeficiency Virus: Systematic Review and Meta-Analysis of Diagnostic Test Accuracy Studies. 
  • Cryptococcosis diagnosis and treatment: What do we know now. 
  • Cryptococcosis. 
  • Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States. 
  • Cryptococcus gattii with bimorphic colony types in a dog in western Oregon: additional evidence for expansion of the Vancouver Island outbreak. 
  • Cryptococcus transmission through solid organ transplantation in the United States: A report from the Ad Hoc Disease Transmission Advisory Committee. 
  • Cryptococcus-like changes in the setting of vasculitis. 
  • Discovery of a modified tetrapolar sexual cycle in Cryptococcus amylolentus and the evolution of MAT in the Cryptococcus species complex. 
  • Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans. 
  • E Pluribus Unum: The Fungal Kingdom as a Rosetta Stone for Biology and Medicine. 
  • Epidemiology and outcome of invasive fungal infections in solid organ transplant recipients. 
  • Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex. 
  • Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection. 
  • First contemporary case of human infection with Cryptococcus gattii in Puget Sound: evidence for spread of the Vancouver Island outbreak. 
  • First reported case of Cryptococcus gattii in the Southeastern USA: implications for travel-associated acquisition of an emerging pathogen. 
  • Fungal diagnosis: how do we do it and can we do better? 
  • Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination. 
  • Gene Network Polymorphism Illuminates Loss and Retention of Novel RNAi Silencing Components in the Cryptococcus Pathogenic Species Complex. 
  • Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Cryptococcus Pathogens. 
  • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. 
  • Host defenses against cryptococcosis. 
  • Human natural killer cells do not inhibit growth of Cryptococcus neoformans in the absence of antibody. 
  • In vitro phagocytosis and intracellular fate of variously encapsulated strains of Cryptococcus neoformans. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • Killing of Cryptococcus neoformans by rat alveolar macrophages. 
  • Know your enemy: how to build and vanquish a global fungal scourge. 
  • Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity. 
  • Macrophage-mediated fungistasis: requirement for a macromolecular component in serum. 
  • Method for the purification of Filobasidiella neoformans basidiospores by flow cytometry. 
  • Mitotic Recombination and Adaptive Genomic Changes in Human Pathogenic Fungi. 
  • Molecular and genetic evidence for a tetrapolar mating system in the basidiomycetous yeast Kwoniella mangrovensis and two novel sibling species. 
  • Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States. 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii. 
  • Nitrogen source-dependent capsule induction in human-pathogenic cryptococcus species. 
  • Opsonic activity of cerebrospinal fluid in experimental cryptococcal meningitis. 
  • Phagocytosis and killing of Cryptococcus neoformans by rat alveolar macrophages in the absence of serum. 
  • Phagocytosis of Cryptococcus neoformans by rat alveolar macrophages. 
  • Phylogenetic analysis of phenotypically characterized Cryptococcus laurentii isolates reveals high frequency of cryptic species. 
  • Phylogeny and phenotypic characterization of pathogenic Cryptococcus species and closely related saprobic taxa in the Tremellales. 
  • Plants promote mating and dispersal of the human pathogenic fungus Cryptococcus. 
  • Prevalence of clinical isolates of Cryptococcus gattii serotype C among patients with AIDS in Sub-Saharan Africa. 
  • Production of the hexitol D-mannitol by Cryptococcus neoformans in vitro and in rabbits with experimental meningitis. 
  • RNAi is a critical determinant of centromere evolution in closely related fungi. 
  • Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species. 
  • Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. 
  • Separation of chromosomes of Cryptococcus neoformans by pulsed field gel electrophoresis. 
  • Sex and virulence of human pathogenic fungi. 
  • Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages. 
  • Strain variation in antiphagocytic activity of capsular polysaccharides from Cryptococcus neoformans serotype A. 
  • Strain variation in composition and molecular size of the capsular polysaccharide of Cryptococcus neoformans serotype A. 
  • Successful treatment of cryptococcal ventriculoatrial shunt infection with systemic therapy alone. 
  • Successful treatment of disseminated cryptococcal infection in a pediatric acute lymphoblastic leukemia patient during induction. 
  • The Evolution of Sexual Reproduction and the Mating-Type Locus: Links to Pathogenesis of Cryptococcus Human Pathogenic Fungi. 
  • The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. 
  • The mating type locus (MAT) and sexual reproduction of Cryptococcus heveanensis: insights into the evolution of sex and sex-determining chromosomal regions in fungi. 
  • The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. 
  • Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target. 
  • Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans. 
  • Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients. 
  • Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. 
  • Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. 
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  Keywords of People

  • Yadav, Vikas, Postdoctoral Associate, Molecular Genetics and Microbiology