Cyclobutanes

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  Subject Areas on Research

  • (+/-)-cis-2-acetoxycyclobutyltrimethylammonium iodide: a semirigid analogue of acetylcholine. 
  • (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterization. 
  • Catatonia and psychosis associated with sibutramine: a case report and pathophysiologic correlation. 
  • Clinical trial issues in weight-loss therapy. 
  • Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis. 
  • Effect of moderate weight loss on health-related quality of life: an analysis of combined data from 4 randomized trials of sibutramine vs placebo. 
  • Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. 
  • Mechanically induced scission and subsequent thermal remending of perfluorocyclobutane polymers. 
  • Stress-responsive polymers containing cyclobutane core mechanophores: reactivity and mechanistic insights. 
  • The clinical treatment of childhood obesity. 
  • The first synthetic studies on pestalotiopsin A. A stereocontrolled approach to the functionalised bicyclic core.