Cytoplasm

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  Subject Areas on Research

  • A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers. 
  • A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2. 
  • A comparative analysis of embryo implantation potential in patients with severe teratozoospermia undergoing in-vitro fertilization with a high insemination concentration or intracytoplasmic sperm injection. 
  • A conserved G₁ regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm. 
  • A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster. 
  • A new stain for systemic fungi in tissue. 
  • A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo. 
  • A region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state. 
  • A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells. 
  • APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export. 
  • ATM binds to beta-adaptin in cytoplasmic vesicles. 
  • ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. 
  • Actin and myosin biochemistry in relation to cytokinesis. 
  • Activation of human B lymphocytes. XIII. Characterization of multiple populations of naturally occurring immunoregulatory cells of polyclonally induced in vitro human B cell function. 
  • Activation of human granulocytes by arachidonic acid: its use and limitations for investigating granulocyte functions. 
  • Acute toxicity of lead particulates on pulmonary alveolar macrophages. Ultrastructural and microanalytical studies. 
  • Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm. 
  • All aboard the cyclin train: subcellular trafficking of cyclins and their CDK partners. 
  • Altered cytoplasmic/nuclear distribution of the c-myc protein in differentiating ML-1 human myeloid leukemia cells. 
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. 
  • An analysis of clinical and laboratory features of acute lymphocytic leukemias with emphasis on 35 children with pre-B leukemia. 
  • An ultrastructural study of C-type virion assembly in mouse cells. 
  • An ultrastructural study of the developing urogenital tract in early human fetuses. 
  • Analysis of cytoplasmic antigens of the yeast and mycelial phases of Candida albicans by two-dimensional electrophoresis. 
  • Analysis of nuclear fiber cell cytoplasmic texture in advanced cataractous lenses from Indian subjects using Debye-Bueche theory. 
  • Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. 
  • Ankyrins. Adaptors between diverse plasma membrane proteins and the cytoplasm. 
  • Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors. 
  • Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton. 
  • Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. 
  • Association between human erythrocyte calmodulin and the cytoplasmic surface of human erythrocyte membranes. 
  • Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein. 
  • Asymmetric distribution of nuclear pore complexes and the cytoplasmic localization of beta2-tubulin mRNA in Chlamydomonas reinhardtii. 
  • Benign vaginal rhabdomyoma: a light and electron microscopic study. 
  • Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling. 
  • Binding of deoxyribonuclease I to actin: a new way to visualize microfilament bundles in nonmuscle cells. 
  • C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. 
  • Cell adhesion protein expression in melanocytic matricoma. 
  • Cell penetration properties of maurocalcine, a natural venom peptide active on the intracellular ryanodine receptor. 
  • Cell-cycle checkpoints that ensure coordination between nuclear and cytoplasmic events in Saccharomyces cerevisiae. 
  • Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus. 
  • Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells. 
  • Characterization of 57 kDa statin as a true marker for growth arrest in tissue by its disappearance from regenerating liver. 
  • Cholecystokinin cells purified by fluorescence-activated cell sorting respond to monitor peptide with an increase in intracellular calcium. 
  • Complexity of cytoplasmic polyadenylated and nonpolyadenylated rat brain ribonucleic acids. 
  • Coupling of a mutated form of the human beta 2-adrenergic receptor to Gi and Gs. Requirement for multiple cytoplasmic domains in the coupling process. 
  • Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. 
  • Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. 
  • Cysteine and glutathione levels in developing rat kidney and liver. 
  • Cytology of 575 young women with prenatal exposure to diethylstilbestrol. 
  • Cytology of clear-cell adenocarcinoma of genital tract in young females: review of 95 cases from the registry. 
  • Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. 
  • Cytoplasmic dynein is required to oppose the force that moves nuclei towards the hyphal tip in the filamentous ascomycete Ashbya gossypii. 
  • Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular components. 
  • Cytoplasmic myosin from Drosophila melanogaster. 
  • Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. 
  • Deep hypothermia markedly activates the small ubiquitin-like modifier conjugation pathway; implications for the fate of cells exposed to transient deep hypothermic cardiopulmonary bypass. 
  • Definition of a consensus transportin-specific nucleocytoplasmic transport signal. 
  • Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated. 
  • Diagnosis of anaplastic large-cell lymphoma, including multifocal osseous KI-1 lymphoma, by fine-needle aspiration biopsy. 
  • Differences in steroid specificity for rat androgen binding protein and the cytoplasmic receptor. 
  • Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells. 
  • Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. 
  • Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. 
  • Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. 
  • Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. 
  • Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. 
  • Dynamic positioning of mitotic spindles in yeast: role of microtubule motors and cortical determinants. 
  • Dynamic shuttling and intranuclear mobility of nuclear hormone receptors. 
  • Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. 
  • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. 
  • Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages. 
  • Effects of electroporation on transmembrane potential induced by defibrillation shocks. 
  • Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line. 
  • Effects of the src gene product on microfilament and microtubule organization in avian and mammalian cells infected with the same temperature-sensitive mutant of Rous sarcoma virus. 
  • Electron microprobe analysis of human labial gland secretory granules in cystic fibrosis. 
  • Electron microscopic virus-like material in systemic lupus erythematosus: with preliminary immunologic observations on presence of measles antigen. 
  • Elemental composition of Na pump inhibited rabbit aorta VSM cells by electron probe X-ray microanalysis. 
  • Elemental composition of polyphosphate-containing vacuoles and cytoplasm of Leishmania major. 
  • Endocytosis of the type III transforming growth factor-beta (TGF-beta) receptor through the clathrin-independent/lipid raft pathway regulates TGF-beta signaling and receptor down-regulation. 
  • Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix. 
  • Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression. 
  • Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. 
  • Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease. 
  • Erythropoietin hypersensitivity in primary familial and congenital polycythemia: role of tyrosines Y285 and Y344 in erythropoietin receptor cytoplasmic domain. 
  • Establishment of three-dimensional cultures of human pancreatic duct epithelial cells. 
  • Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. 
  • Expanded polyglutamine stretches form an 'aggresome'. 
  • Experience with subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) on unfertilized aged human oocytes. 
  • Exposure to hyperoxia induces p53 expression in mouse lung epithelium. 
  • Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms. 
  • Expression of terminin, a senescence-related cytoplasmic protein, in the aging rat brain. 
  • Female fertility is reduced in mice lacking Ca2+/calmodulin-dependent protein kinase IV. 
  • Female steroid hormones and target cell nuclei. 
  • Fine needle aspiration biopsy of metastatic melanoma. A morphologic analysis of 174 cases. 
  • Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: A cytomorphologic study of 139 cases with statistical analysis. 
  • Fine-needle aspiration cytology findings in a case of aggressive angiomyxoma: a case report and review of the literature. 
  • Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin. 
  • Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. 
  • Fourier analysis of cytoplasmic texture in nuclear fiber cells from transparent and cataractous human and animal lenses 
  • FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli. 
  • Function and regulation of calmodulin in endocrine cells. 
  • Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling. 
  • Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells. 
  • Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene. 
  • Giant cell interstitial pneumonia in a hard-metal worker. Cytologic, histologic and analytical electron microscopic investigation. 
  • Gibberellin signaling: biosynthesis, catabolism, and response pathways. 
  • Glycoprotein B of human herpesvirus 8 is a component of the virion in a cleaved form composed of amino- and carboxyl-terminal fragments. 
  • Growth and lability of Chaetopterus oocyte mitotic spindles isolated in the presence of porcine brain tubulin. 
  • Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. 
  • HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172. 
  • HMW-2, the Sertoli cell cytoplasmic dynein from rat testis, is a dimer composed of nearly identical subunits. 
  • Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells. 
  • Human immunodeficiency virus: nuclear RNA export unwound. 
  • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. 
  • Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1. 
  • Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse. 
  • Identification of a somatodendritic targeting signal in the cytoplasmic domain of the transferrin receptor. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis. 
  • IgG-lambda plasma cell myeloma with cytoplasmic azurophilic inclusion bodies. 
  • Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression. 
  • Immunohistochemical differentiation of sarcomatoid mesotheliomas from other spindle cell neoplasms. 
  • Immunoreaction at 43 kDa with anti-ubiquitin antibody in breast neoplasms. 
  • Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy. 
  • In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail. 
  • Increased expression of p130 in Alzheimer disease. 
  • Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. 
  • Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1. 
  • Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. 
  • Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release. 
  • Intrinsic and cyclin-dependent kinase-dependent control of spindle pole body duplication in budding yeast. 
  • Involvement of R-cadherin in the early stage of glomerulogenesis. 
  • Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies. 
  • L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro. 
  • LOCALIZATION OF IMMUNOGLOBULINS IN CHRONIC THYROIDITIS. 
  • Late intracytoplasmic sperm injection in unexpected failed fertilization in vitro: diagnostic or therapeutic? 
  • Leprosy in a mangabey monkey--naturally acquired infection. 
  • Leukocyte rolling on P-selectin: a three-dimensional numerical study of the effect of cytoplasmic viscosity. 
  • Lipid-rich variant of a pancreatic endocrine neoplasm in an endoscopic ultrasound-guided fine needle aspiration biopsy. 
  • Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. 
  • Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. 
  • Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes. 
  • Mapping the ankyrin-binding site of the human erythrocyte anion exchanger. 
  • Mechanisms regulating SHORT-ROOT intercellular movement. 
  • Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. 
  • Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14. 
  • Metabolism of levulinate in perfused rat livers and live rats: conversion to the drug of abuse 4-hydroxypentanoate. 
  • Mitochondrial localization and characterization of 99Tc-SESTAMIBI in heart cells by electron probe X-ray microanalysis and 99Tc-NMR spectroscopy. 
  • Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor. 
  • Molecular basis of disease susceptibility in the Texas cytoplasm of maize. 
  • Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae. 
  • Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny. 
  • Morphogenesis of Candida albicans and cytoplasmic proteins associated with differences in morphology, strain, or temperature. 
  • Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. 
  • Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding. 
  • Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. 
  • NDRG4 is required for cell cycle progression and survival in glioblastoma cells. 
  • Negative regulation of Armadillo, a Wingless effector in Drosophila. 
  • New insights into Chlamydia intracellular survival mechanisms. 
  • Nonsense mediated decay induced by tethered human UPF3B is restricted to the cytoplasm. 
  • Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. 
  • Nuclear export of mammalian PERIOD proteins. 
  • Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells. 
  • Nuclear protein localization. 
  • Nuclear repulsion enables division autonomy in a single cytoplasm. 
  • Nucleo-cytoplasmic interactions that control nuclear envelope breakdown and entry into mitosis in the sea urchin zygote. 
  • Nucleocytoplasmic shuttling by protein nuclear import factors. 
  • Nucleocytoplasmic trafficking of G2/M regulators in yeast. 
  • OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis. 
  • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. 
  • Oncogenic activation of c-ABL by mutation within its last exon. 
  • One-dimensional crystals of (Na+ + K+)-ATPase dimers. 
  • Onset of feedback reactions underlying vertebrate rod photoreceptor light adaptation. 
  • Parc-ing p53 in the cytoplasm. 
  • Pathologic quiz case: pituitary mass in a 48-year-old woman. 
  • Percutaneous epididymal sperm aspiration and intracytoplasmic sperm injection in the management of infertility due to obstructive azoospermia. 
  • Polyspecific reactivity of a murine monoclonal antibody that binds to nuclear matrix-associated, chromatin-bound autoantigens. 
  • Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro. 
  • Posttranslational regulation of TCR Valpha allelic exclusion during T cell differentiation. 
  • Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin. 
  • Principles that govern competition or co-existence in Rho-GTPase driven polarization. 
  • Probing bacterial gene expression within host cells. 
  • Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control. 
  • Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. 
  • Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. 
  • Quantitative laser scanning confocal autofluorescence microscopy of normal, premalignant, and malignant colonic tissues. 
  • RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses. 
  • RNA interference in human cells is restricted to the cytoplasm. 
  • Rapid flow of passive neutrophils into a 4 microns pipet and measurement of cytoplasmic viscosity. 
  • Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and beta-arrestin 2 during homologous desensitization of the substance P receptor. 
  • Reconstitution of Ca(2+)-dependent K+ transport in erythrocyte membrane vesicles requires a cytoplasmic protein. 
  • Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. 
  • Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19. 
  • Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. 
  • Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes. 
  • Regulation of the Saccharomyces cerevisiae Slt2 kinase pathway by the stress-inducible Sdp1 dual specificity phosphatase. 
  • Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. 
  • Response of bone marrow to MC29 avian leukosis virus in vitro. 
  • Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes. 
  • Rheological properties of living cytoplasm: a preliminary investigation of squid axoplasm (Loligo pealei). 
  • Rheological properties of living cytoplasm: endoplasm of Physarum plasmodium. 
  • Role of the cytoplasmic tails of CXCR1 and CXCR2 in mediating leukocyte migration, activation, and regulation. 
  • Selective regulation of expression of protein kinase C beta isoenzymes occurs via alternative splicing. 
  • Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling. 
  • Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. 
  • Speciation Matters: Bioavailability of Silver and Silver Sulfide Nanoparticles to Alfalfa (Medicago sativa). 
  • Spectrin-based membrane skeleton: a multipotential adaptor between plasma membrane and cytoplasm. 
  • Spectrin: a structural mediator between diverse plasma membrane proteins and the cytoplasm. 
  • Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. 
  • Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. 
  • Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex. 
  • Structural characterization of ordered arrays of sn-glycerol-3-phosphate acyltransferase from Escherichia coli. 
  • Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. 
  • Structural requirements for association of neurofascin with ankyrin. 
  • Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. 
  • Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation. 
  • Subcellular changes in capillary endothelial cells during repair of hyperoxic lung injury. 
  • Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus. 
  • Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. 
  • Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. 
  • Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. 
  • Tau deficiency leads to the upregulation of BAF-57, a protein involved in neuron-specific gene repression. 
  • Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs. 
  • The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. 
  • The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. 
  • The Cth2 ARE-binding protein recruits the Dhh1 helicase to promote the decay of succinate dehydrogenase SDH4 mRNA in response to iron deficiency. 
  • The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression. 
  • The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. 
  • The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis. 
  • The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. 
  • The bushy cells in the anteroventral cochlear nucleus of the cat. A study with the electron microscope. 
  • The carbohydrates in frog retinal rod outer segments. 
  • The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. 
  • The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. 
  • The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. 
  • The dishevelled protein is modified by wingless signaling in Drosophila. 
  • The effect of cell size on the pathologic diagnosis of small and large cell carcinomas of the lung. 
  • The effects of local progesterone on stilbestrol-associated vaginal adenosis. 
  • The final touches make perfect the peptide-MHC class I repertoire. 
  • The genetics of sex ratio distortion by cytoplasmic infection under maternal and contagious transmission: an epidemiological study. 
  • The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. 
  • The human cytokine I-309 is a monocyte chemoattractant. 
  • The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking. 
  • The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localization. 
  • The phosphorylation state of the FIGQY tyrosine of neurofascin determines ankyrin-binding activity and patterns of cell segregation. 
  • The prevalence of abnormal cilia in normal pediatric lungs. 
  • The products of gene I and the overlapping in-frame gene XI are required for filamentous phage assembly. 
  • The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy. 
  • The role of the L3T4 molecule in mitogen and antigen-activated signal transduction. 
  • The soluble metalloendoprotease required in myoblast fusion remains intracellular. 
  • The subcellular localization of syntaxin 17 varies among different cell types and is altered in some malignant cells. 
  • Transcription and processing of human microRNA precursors. 
  • Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. 
  • Ultrastructural changes accompanying secretion and cell death in the molting glands of an insect (Oncopeltus). 
  • Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model. 
  • Ultrastructure and x-ray microanalysis of macrophages exposed to cadmium chloride. 
  • Unidirectional dominance of cytoplasmic inheritance in two genetic crosses of Plasmodium falciparum. 
  • Virus-induced genitourinary malignancy. Macromolecular identity. 
  • Viscosity of passive human neutrophils undergoing small deformations. 
  • Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. 
  • alpha(1)-adrenergic receptors mediate LH-releasing hormone secretion through phospholipases C and A(2) in immortalized hypothalamic neurons. 
  • cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. 
  • zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Juvvadi, Praveen Rao, Assistant Professor in Pediatrics, Pediatrics, Infectious Diseases
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Steinbach, William J., Professor of Pediatrics, Molecular Genetics and Microbiology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology