Cytosine

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  Subject Areas on Research

  • A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression. 
  • A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. 
  • Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC-->TT transitions. 
  • Analysis of the mouse transcriptome for genes involved in the function of the nervous system. 
  • Bacterial infection remodels the DNA methylation landscape of human dendritic cells. 
  • Base modifications in plasmid DNA caused by potassium permanganate. 
  • Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. 
  • Bisulfite pyrosequencing. 
  • Brincidofovir (CMX001) Toxicity Associated With Epithelial Apoptosis and Crypt Drop Out in a Hematopoietic Cell Transplant Patient: Challenges in Distinguishing Drug Toxicity From GVHD. 
  • Brincidofovir for Asymptomatic Adenovirus Viremia in Pediatric and Adult Allogeneic Hematopoietic Cell Transplant Recipients: A Randomized Placebo-Controlled Phase II Trial. 
  • Callipyge mutation affects gene expression in cis: a potential role for chromatin structure. 
  • Characterizing the protonation state of cytosine in transient G·C Hoogsteen base pairs in duplex DNA. 
  • Cocaine shapes chromatin landscapes via Tet1. 
  • Combined activity of amphotericin B and 5-fluorocytosine against Cryptococcus neoformans in vitro and in vivo in mice. 
  • Combined therapy with amphotericin B and 5-fluorocytosine for Candida meningitis. 
  • Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA. 
  • Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance. 
  • Cytosine deaminase MX cassettes as positive/negative selectable markers in Saccharomyces cerevisiae. 
  • Cytosine deamination in mismatched base pairs. 
  • Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts. 
  • DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs. 
  • DNA methylation atlas of the mouse brain at single-cell resolution. 
  • Direct evidence for (G)O6···H2-N4(C)+ hydrogen bonding in transient G(syn)-C+ and G(syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance R1ρ relaxation dispersion measurements. 
  • Early de novo DNA methylation and prolonged demethylation in the muscle lineage. 
  • Echinomycin, a bis-intercalating agent, induces C-->T mutations via cytosine deamination. 
  • Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction. 
  • Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression. 
  • Free radicals formed by exposure of pyrimidine solids to sodium atoms: an electron spin resonance study. 
  • HDV ribozyme activity in monovalent cations. 
  • HDV ribozymes. 
  • Hepatic candidiasis: persistent pyrexia in a patient with acute myeloid leukaemia after recovery from consolidation therapy-induced neutropenia. 
  • Hydrolysis of N3-methyl-2'-deoxycytidine: model compound for reactivity of protonated cytosine residues in DNA. 
  • Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme. 
  • Incorporation of CC steps into Z-DNA: interplay between B-Z junction and Z-DNA helical formation. 
  • Infrared Spectroscopic Observation of a G-C+ Hoogsteen Base Pair in the DNA:TATA-Box Binding Protein Complex Under Solution Conditions. 
  • Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage. 
  • Kinetics of bisulfite-induced cytosine deamination in single-stranded DNA. 
  • Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. 
  • Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine. 
  • Ocular penetration of 5-fluorocytosine. 
  • Phase II study of troxacitabine (BCH-4556) in patients with advanced non-small-cell lung cancer. 
  • Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS. 
  • Progressive multifocal leukoencephalopathy following heightened immunosuppression after lung transplant. 
  • Recovery from disseminated candidiasis in a premature neonate. 
  • Revisiting the Hole Size in Double Helical DNA with Localized Orbital Scaling Corrections. 
  • Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. 
  • Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation. 
  • Site-specific methylases induce the SOS DNA repair response in Escherichia coli. 
  • Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children. 
  • Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia. 
  • Susceptibility of Aspergillus to 5-fluorocytosine and amphotericin B alone and in combination. 
  • The exon A (C77G) mutation is a common cause of abnormal CD45 splicing in humans. 
  • The human T-cell leukemia virus-1 transcriptional activator Tax enhances cAMP-responsive element-binding protein (CREB) binding activity through interactions with the DNA minor groove. 
  • The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. 
  • Three Pyrimidine Decarboxylations in the Absence of a Catalyst. 
  • Transposon Tn5 target specificity: preference for insertion at G/C pairs. 
  • Treatment of experimental cryptococcal meningitis with amphotericin B, 5-fluorocytosine, and ketoconazole. 
  • Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. 
  • Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization.