Cytotoxicity, Immunologic
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Subject Areas on Research
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1 alpha,25 Dihydroxyvitamin D3 and mononuclear phagocytes: enhancement of mouse macrophage and human monocyte hydrogen peroxide production without alteration of tumor cytolysis.
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2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.
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A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.
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A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model.
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A cytotoxic proteinase isolated from human lymphocytes.
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A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo.
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A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
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A monoclonal antibody reactive with a second epitope of the 67,000-dalton human T cell antigen.
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A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes.
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A synthetic peptide homologous to the envelope proteins of retroviruses inhibits monocyte-mediated killing by inactivating interleukin 1.
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Abrogation of baboon natural xenoantibody to pig splenocytes by DL-penicillamine.
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Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen-specific T-cell responses.
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Activated lymphocytes promote endothelial cell detachment from matrix: a role for modulation of endothelial cell beta 1 integrin affinity.
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Active immunization using dendritic cells mixed with tumor cells inhibits the growth of primary breast cancer.
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Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer.
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Age-related development of human anti-pig xenoantibody.
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Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma.
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Alpha-glycosylceramides enhance the antitumor cytotoxicity of hepatic lymphocytes obtained from cancer patients by activating CD3-CD56+ NK cells in vitro.
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Analysis of the relationship between stage of differentiation and NK/LAK susceptibility of colon carcinoma cells.
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Anti-glycoprotein D monoclonal antibody protects against herpes simplex virus type 1-induced diseases in mice functionally depleted of selected T-cell subsets or asialo GM1+ cells.
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Anti-self HLA may be clonally expressed.
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Antibody-dependent enhancement of human immunodeficiency virus type 1 (HIV-1) infection in vitro by serum from HIV-1-infected and passively immunized chimpanzees.
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Association of chronic thromboxane inhibition with reduced in situ cytotoxic T cell activity in rejecting rat renal allografts.
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Astrocyte cytolysis by MHC class II-specific mouse T cell clones.
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Autologous bone marrow transplantation in acute myelogenous leukemia: in vitro treatment with myeloid-specific monoclonal antibodies and drugs in combination.
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Autologous lymph node cell-derived tumor-specific cytotoxic T-cells for use in adoptive immunotherapy of human melanoma.
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B cell-ablative therapy for the treatment of autoimmune diseases.
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CD2-mediated IL-12-dependent signals render human gamma delta-T cells resistant to mitogen-induced apoptosis, permitting the large-scale ex vivo expansion of functionally distinct lymphocytes: implications for the development of adoptive immunotherapy strategies.
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CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells.
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CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver.
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CD86 (B7-2) can function to drive MHC-restricted antigen-specific CTL responses in vivo.
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Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides.
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Carbohydrate changes in pre- and peri-implantation mouse embryos as detected by a monoclonal antibody.
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Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation.
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Cell surface F1Fo ATP synthase: a new paradigm?
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Cell surface reactive human monoclonal antibody directed to human melanoma-associated gangliosides.
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Cell-mediated cytotoxicity of murine cytomegalovirus-infected target cells allows for release of residual infectious virus.
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Cells treated with TAP-2 antisense oligonucleotides are potent antigen-presenting cells in vitro and in vivo.
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Cellular immune response to cryptic epitopes during therapeutic gene transfer.
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Cerebrospinal fluid macrophage response to experimental cryptococcal meningitis: relationship between in vivo and in vitro measurements of cytotoxicity.
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Characterization of T cells expressing the gamma/delta antigen receptor in human renal allografts.
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Characterization of cytotoxic cells generated from in vitro cultures of murine bone marrow cells.
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Characterization of the effects of endotoxin on macrophage tumor cell killing.
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Characterization of tumor-specific cytotoxic effector cells with a novel CD3-/Thy-1+ phenotype.
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Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens.
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Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression.
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Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers.
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Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines.
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Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation.
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Combined total lymphoid irradiation and cyclosporine promote xenograft survival.
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Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.
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Comparison of the relative cytotoxic effector cell capabilities and the proportions of cells bearing various surface markers in human tonsil and peripheral blood mononuclear cells.
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Complement sensitivity of paroxysmal nocturnal hemoglobinuria bone marrow cells.
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Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses.
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Correlation between interferon- gamma secretion and cytotoxicity, in virus-specific memory T cells.
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Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity.
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Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses.
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Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state.
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Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity.
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Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity.
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DNA array-based gene profiling in tumor immunology.
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Defective antitumor responses in CX3CR1-deficient mice.
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Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3.
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Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.
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Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?
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Detection of pyroptosis by measuring released lactate dehydrogenase activity.
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Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.
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Discordant complement systems as a factor in hyperacute xenograft rejection.
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Effector mechanisms of cytolytically activated macrophages. II. Secretion of a cytolytic factor by activated macrophages and its relationship to secreted neutral proteases.
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Effects of antifungal agents and gamma interferon on macrophage cytotoxicity for fungi and tumor cells.
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Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
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Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules.
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Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.
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Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model.
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Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection.
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Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates.
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Enhancement of macrophage-mediated tumor cell killing by bacterial outer membrane proteins (porins).
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Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus.
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Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors.
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Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7. Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation.
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Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gammadelta-T cells: implications in the design of gammadelta-T-cell-based immunotherapies for pancreatic cancer.
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Extended evaluation of a phase 1/2 trial on dosing, safety, immunogenicity, and overall survival after immunizations with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine in late-stage colorectal cancer.
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Failure of monoclonal antibodies against tumor associated antigens to improve tumor targeting of LAK cells in a model of rat colon carcinoma.
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Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.
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Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice.
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Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.
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Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.
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Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells.
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Genome-scale screens identify factors regulating tumor cell responses to natural killer cells.
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Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo.
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Graft hyporeactivity induced by donor-derived dendritic cell progenitors.
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Graft-versus-host disease: the viewpoint from the donor T cell.
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HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes.
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HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection.
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Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses.
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Hepatic transplantation into sensitized recipients. Demonstration of hyperacute rejection.
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Human T cells specifically activated against autologous malignant melanoma.
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Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack.
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Human cytotoxic T cells specific for autologous melanoma cells: successful generation from lymph node cells in seven consecutive cases.
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Human dendritic cells transfected with RNA encoding prostate-specific antigen stimulate prostate-specific CTL responses in vitro.
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Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1.
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Human natural killer cells do not inhibit growth of Cryptococcus neoformans in the absence of antibody.
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Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
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Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells.
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IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection.
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Identification and functional analysis of human natural anti-pig xenoantibodies.
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Identification of a tumor associated antigen that can induce tumor specific cytotoxicity.
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Immune responses of human lymphocytes in vitro.
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Immune-inflammation gene signatures in endometriosis patients.
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Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity.
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Immunogenic determinants of a neuropathogenic murine leukemia virus.
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Immunologic and virologic analyses of an acutely HIV type 1-infected patient with extremely rapid disease progression.
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Immunologic control of the ascites form of murine adenocarcinoma 755. II. Tumor immunity associated with a Friend--Moloney--Ra,scher-type virus.
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Immunologic control of the ascites form of murine adenocarcinoma 755. V. Antibody-directed macrophages mediate tumor cell destruction.
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Immunologic targeting of FOXP3 in inflammatory breast cancer cells.
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Immunological memory induced by genetically transduced tumor cells.
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Immunology. Outwitted by viral RNAs.
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Immunotherapy Gone Viral: Bortezomib and oHSV Enhance Antitumor NK-Cell Activity.
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Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.
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Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon gamma.
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Implications of leukoregulin to autologous tumor-specific human T-cell populations.
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In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia.
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In situ and systemic cellular immunity associated with orthotopic rat liver allograft acceptance or rejection.
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In vitro function of indium-111 oxine-labeled human monocytes.
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In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides.
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In vitro modulation of macrophage tumoricidal activity: partial characterization of a macrophage-activating factor(s) in supernatants of NaIO4-treated peritoneal cells.
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In vivo lysis of L5178Y cells in the establishment of the tumor-dormant state in DBA/2 mice.
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In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate.
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Induction in vitro of primary cytotoxic T-lymphocyte responses with DNA encoding herpes simplex virus proteins.
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Induction of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T lymphocyte responses in seronegative adults by a nonreplicating, host-range-restricted canarypox vector (ALVAC) carrying the HIV-1MN env gene.
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Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA.
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Induction of primary, antiviral cytotoxic, and proliferative responses with antigens administered via dendritic cells.
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Induction of protective CTL responses in newborn mice by a murine retrovirus.
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Inhibition of T cell costimulation by VCAM-1 prevents murine graft-versus-host disease across minor histocompatibility barriers.
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Inhibition of human natural killer cell activity by a synthetic peptide homologous to a conserved region in the retroviral protein, p15E.
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Innate anti-breast cancer immunity of apoptosis-resistant human gammadelta-T cells.
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Interferon-mediated protection of B16 melanoma cells from cytotoxicity by activated macrophages.
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Intracellular adhesion molecule-1 modulates beta-chemokines and directly costimulates T cells in vivo.
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Involvement of histo-blood-group antigens in the susceptibility of colon carcinoma cells to natural killer-mediated cytotoxicity.
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Kinetics of expansion of SIV Gag-specific CD8+ T lymphocytes following challenge of vaccinated macaques.
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Leishmania species: mechanisms of complement activation by five strains of promastigotes.
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Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells.
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Leukocyte composition of human breast cancer.
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Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.
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Loss of tumorigenicity following in vitro MuLV infection is associated with induction of peritoneal natural killer cell activity.
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Ly49-dependent NK cell licensing and effector inhibition involve the same interaction site on MHC ligands.
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Lymphokine-activated killer cell activity after cryopreservation.
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M-HIFU inhibits tumor growth, suppresses STAT3 activity and enhances tumor specific immunity in a transplant tumor model of prostate cancer.
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Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity.
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Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV.
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Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases.
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Mechanisms of the antioxidant effects of nitric oxide.
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Melanoma-specific cytotoxic T cells generated from peripheral blood lymphocytes. Implications of a renewable source of precursors for adoptive cellular immunotherapy.
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Metastatic colorectal cancer cells from patients previously treated with chemotherapy are sensitive to T-cell killing mediated by CEA/CD3-bispecific T-cell-engaging BiTE antibody.
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Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice.
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Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens.
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Modulation of in vitro autologous melanoma-specific cytotoxic T-cell responses by phorbol dibutyrate and ionomycin.
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Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s).
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Monensin enhances the cytotoxic effect of antitransferrin receptor immunotoxin on cultured RPE cells.
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Monolayer absorption of human cytotoxic T cells: evidence for clonality.
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Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
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Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA.
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Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity.
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NK and LAK susceptibility varies inversely with target cell MHC class I antigen expression in a rat epithelial tumour system.
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NK susceptibility varies inversely with target cell class I HLA antigen expression.
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NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway.
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NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.
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Natural antipig xenoantibody is absent in neonatal human serum.
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Natural killer cell infection and inactivation in vitro by the human immunodeficiency virus.
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Natural killer cell-endothelial cell interactions in xenotransplantation.
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Natural killing target antigens as inducers of interferon: studies with an immunoselected, natural killing-resistant human T lymphoblastoid cell line.
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Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection.
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Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors.
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New approaches to HIV vaccine development.
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Newborn baboon serum anti-alpha galactosyl antibody levels and cytotoxicity to cultured pig kidney (PK15) cells.
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Noncytolytic CD8 T cell-mediated suppression of HIV replication.
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Oncolytic immunotherapy through tumor-specific translation and cytotoxicity of poliovirus.
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Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
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Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.
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Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
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Orphan nuclear receptors in T lymphocyte development.
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Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells.
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Overlapping epitopes in human immunodeficiency virus type 1 gp120 presented by HLA A, B, and C molecules: effects of viral variation on cytotoxic T-lymphocyte recognition.
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Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity.
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Perforin knockout mice, but not mice with MAIDS, show protection against experimental cytomegalovirus retinitis after adoptive transfer of immune cells with a functional perforin cytotoxic pathway.
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Phagocytosis and killing of Cryptococcus neoformans by rat alveolar macrophages in the absence of serum.
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Phase I studies of recombinant interferon-gamma.
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Phase I trial of interleukin-2 plus doxorubicin.
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Phenotype and function of T cells propagated from donor-specific blood transfusion enhanced and autologous blood transfused rejecting rat renal allografts.
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Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.
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Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.
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Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture.
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Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.
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Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs.
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Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination.
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Priming for virus-specific CD8+ but not CD4+ cytotoxic T lymphocytes with synthetic lipopeptide is influenced by acylation units and liposome encapsulation.
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Prophylactic use of human leukocyte interferon after allogeneic marrow transplantation.
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Protection of mice from Semliki Forest virus infection by lymphocytes treated with low levels of interferon.
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Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.
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RNA-Based Vaccines in Cancer Immunotherapy.
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Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells.
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Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line.
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Recombinant leukocyte A interferon for the treatment of serious viral infections after marrow transplant: a phase I study.
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Recombinant rubella vectors elicit SIV Gag-specific T cell responses with cytotoxic potential in rhesus macaques.
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Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1.
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Relationship between sensitivity to natural killer cells and MHC class-I antigen expression in colon carcinoma cell lines.
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Removal of fibroblasts from human epithelial cell cultures with use of a complement fixing monoclonal antibody reactive with human fibroblasts and monocytes/macrophages.
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Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity.
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Role for hedgehog pathway in regulating growth and function of invariant NKT cells.
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Role of LAT in the granule-mediated cytotoxicity of CD8 T cells.
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Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer.
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Season and size of urban particulate matter differentially affect cytotoxicity and human immune responses to Mycobacterium tuberculosis.
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Selective inhibition of natural killer activity by the monoclonal antibodies OKT10 and VEP10 at the single cell level.
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Self-discrepancy and natural killer cell activity: immunological consequences of negative self-evaluation.
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Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response.
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Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation.
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Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.
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Spontaneous tumor cell killing by human blood monocytes and human peritoneal macrophages: lack of alteration by endotoxin or quenchers of reactive oxygen species.
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Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.
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T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase.
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T-bet:Eomes balance, effector function, and proliferation of cytomegalovirus-specific CD8+ T cells during primary infection differentiates the capacity for durable immune control.
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TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.
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Targeting the Leukemia Antigen PR1 with Immunotherapy for the Treatment of Multiple Myeloma.
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The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes.
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The effect of 15-deoxyspergualin on hamster-to-rat cardiac xenograft survival.
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The effect of soluble complement receptor type 1 on hyperacute xenograft rejection.
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The effects of donor-specific blood transfusion enhancement of rat renal allografts on cytotoxic activity and phenotypes of peripheral blood lymphocytes, splenocytes, and graft-infiltrating cells.
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The effects of leukemosuppressive immunotherapy on thymic infectious cell centers in AKR mice.
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The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness.
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The immunologic constant of rejection.
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The impact of HIV-1 infection on phenotypic and functional parameters of cellular immunity in chimpanzees.
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The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.
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The macrophage as an antineoplastic surveillance cell: biological perspectives.
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The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling.
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The role of transmethylation reactions in regulating the binding of BCG-activated murine macrophages to neoplastic target cells.
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The tumor dormant state. Comparison of L5178Y cells used to establish dormancy with those that emerge after its termination.
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The tumor dormant state. Quantitation of L5178Y cells and host immune responses during the establishment and course of dormancy in syngeneic DBA/2 mice.
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Tumor cell killing by phorbol ester--differentiated human leukemia cells.
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Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor.
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Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells.
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Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning.
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Ultraviolet light exposure suppresses contact hypersensitivity by abrogating endothelial intercellular adhesion molecule-1 up-regulation at the elicitation site.
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Ultraviolet-light-inactivated Cas-Br-M murine leukemia virus induces a protective CD8+ cytotoxic T lymphocyte response in newborn mice.
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Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors.
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Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles.
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Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge.
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Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge.
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Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules.
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XVIII. Effective treatment of AKR leukemia with antibody to gp7 1 eliminates the neonatal burst of ecotropic AKR virus producing cells.
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Keywords of People
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Cianciolo, George James,
Associate Professor Emeritus of Pathology,
Pathology
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
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Palmer, Gregory M.,
Associate Professor of Radiation Oncology,
Radiation Oncology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Shinohara, Mari L.,
Associate Professor of Immunology,
Cell Biology
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Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Immunology
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Zennadi, Rahima,
Associate Professor in Medicine,
Pathology