Dehydroepiandrosterone

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  Subject Areas on Research

  • A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development. 
  • A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. II. Preliminary clinical application--the dehydroepiandrosterone loading test. 
  • A radioimmunoassay for the estimation of serum dehydroepiandrosterone sulphate in normal and pathological sera. 
  • Adolescent depression, cortisol and DHEA. 
  • Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm. 
  • An exploratory pilot investigation of neurosteroids and self-reported pain in female Iraq/Afghanistan-era Veterans. 
  • Androgens and endometrium: new lessons from the corpus luteum via the adrenal cortex? 
  • Association of DHEA, DHEAS, and cortisol with childhood trauma exposure and post-traumatic stress disorder. 
  • Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage. 
  • Cortisol, estradiol, and androgens in acutely ill paranoid schizophrenics. 
  • DHEA enhances emotion regulation neurocircuits and modulates memory for emotional stimuli. 
  • DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action. 
  • Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. 
  • Diagnosing Rhodococcus equi infections in a setting where tuberculosis is highly endemic: a double challenge. 
  • Do dehydroepiandrosterone, progesterone, and testosterone influence women's depression and anxiety levels? Evidence from hair-based hormonal measures of 2105 rural Indian women. 
  • Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. 
  • Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. 
  • Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder. 
  • Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. 
  • High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status. 
  • High, usual and impaired functioning in community-dwelling older men and women: findings from the MacArthur Foundation Research Network on Successful Aging. 
  • Mechanisms and methods in glucose metabolism and cell death. 
  • Modulation of progestin secretion in ovarian cells by 17beta-hydroxy-5alpha-androstan-3-one (dihydrotestosterone): a direct demonstration in monolayer culture. 
  • Neuroactive steroids and PTSD treatment. 
  • Neuroactive steroids and suicidality in posttraumatic stress disorder. 
  • Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia. 
  • Neurosteroid transport by the organic solute transporter OSTα-OSTβ. 
  • Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001. 
  • Phylogenetic comparisons implicate sex hormone-binding globulin in "masculinization" of the female spotted hyena (Crocuta crocuta). 
  • Plasma concentrations of 11-deoxycorticosterone in women during the menstrual cycle. 
  • Precipitous Dehydroepiandrosterone Declines Reflect Decreased Physical Vitality and Function. 
  • Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers. 
  • Puberty and depression. 
  • Reproductive hormone levels in gynecologic oncology patients undergoing surgical castration after spontaneous menopause. 
  • Salmeterol enhances the cardiac response to gene therapy in Pompe disease. 
  • Serum dehydroepiandrosterone (DHA) and sulphate (DHAS) after acute growth hormone therapy. 
  • The association of dehydroepiandrosterone and dehydroepiandrosterone sulfate with anxiety sensitivity and electronic diary negative affect among smokers with and without posttraumatic stress disorder. 
  • The dehydroepiandrosterone loading test. III. A possible placental function test. 
  • The dehydroepiandrosterone loading test. IV. Evaluation of clinical utility. 
  • The effect of leuprolide acetate on ovulation induction with human menopausal gonadotropins in polycystic ovary syndrome. 
  • The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. 
  • The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting-state amygdala connectivity. 
  • The steroid profile of a virilizing ovarian tumor. 
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  Keywords of People

  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology