Demyelinating Diseases

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  Subject Areas on Research

  • A differential diagnosis of central nervous system demyelination: beyond multiple sclerosis. 
  • Anti-N-Methyl-d-Aspartate Receptor Encephalitis Presenting With Features of Kleine-Levin Syndrome and Demyelination. 
  • Association between cell-mediated demyelination and astrocyte stimulation. 
  • CT and MR imaging of Canavan disease. 
  • Chronic inflammatory demyelinating polyradiculoneuropathy of childhood: treatment with high-dose intravenous immunoglobulin. 
  • Circulating adhesion molecules and inflammatory mediators in demyelination: a review. 
  • Conduction block and continuous motor unit activity in chronic acquired demyelinating polyneuropathy. 
  • Diffusion tensor imaging for evaluation of the childhood brain and pediatric white matter disorders. 
  • Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. 
  • Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERα signaling on astrocytes but not through ERβ signaling on astrocytes or neurons. 
  • Estrogen receptor-β ligand treatment after disease onset is neuroprotective in the multiple sclerosis model. 
  • Familial aggregation of multiple myeloma and central nervous system diseases. 
  • High-field (9.4 T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility. 
  • Induction of anti-myelin antibodies in EAE and their possible role in demyelination. 
  • Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats. 
  • Lhermitte's sign in cobalamin (vitamin B12) deficiency. 
  • Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases. 
  • Methylphenidate in neuropsychological sequelae of radiotherapy and chemotherapy of childhood brain tumors and leukemia. 
  • Neuromuscular Disease in the Neurointensive Care Unit. 
  • Neuroradiology case of the day. Multifocal inflammatory leukoencephalopathy due to treatment with 5-fluorouracil and levamisole. 
  • Ocular toxicity following high dose chemotherapy and autologous transplant. 
  • Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. 
  • Purkinje cell loss in experimental autoimmune encephalomyelitis. 
  • Recurrent acute inflammatory demyelinating polyradiculitis after allogeneic bone marrow transplantation. 
  • Schwann cell vulnerability to demyelination is associated with internodal length in tellurium neuropathy. 
  • Small lymphocytic lymphoma presenting as a paraneoplastic syndrome with acute central nervous system demyelination. 
  • Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion. 
  • Structural brain changes revealed by MRI. 
  • Tensor diffusion imaging in B12 leukoencephalopathy. 
  • The development of Lhermitte's sign during cisplatin chemotherapy. Possible drug-induced toxicity causing spinal cord demyelination. 
  • The role of fractalkine (CX3CL1) in regulation of CD4(+) cell migration to the central nervous system in patients with relapsing-remitting multiple sclerosis. 
  • Trichothiodystrophy with dysmyelination and central osteosclerosis. 
  • Very-late-onset adrenoleukodystrophy: possible precipitation of demyelination by cerebral contusion. 
  • When tumefactive demyelination is truly a tumor: case report of a radiographic misdiagnosis. 
  • White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. 
  • Widespread effects of hyperintense lesions on cerebral white matter structure. 
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  Keywords of People

  • McLendon, Roger Edwin, Professor of Pathology, Pathology