Dengue

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  Subject Areas on Research

  • A physical interaction network of dengue virus and human proteins. 
  • A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection. 
  • A prospective case-control study to investigate retinal microvascular changes in acute dengue infection. 
  • Acute Dengue fever causes false-positive reactivity in OraQuick rapid HIV-1/2 antibody test. 
  • Adaptive immune responses to primary and secondary dengue virus infections. 
  • Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection. 
  • An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target. 
  • Analysis of Dengue Serotype 4 in Sri Lanka during the 2012-2013 Dengue Epidemic. 
  • Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis. 
  • Case series of fatal Leptospira spp./dengue virus co-infections-Puerto Rico, 2010-2012. 
  • Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania. 
  • Clinical evaluation of the BioFire Global Fever Panel for the identification of malaria, leptospirosis, chikungunya, and dengue from whole blood: a prospective, multicentre, cross-sectional diagnostic accuracy study. 
  • Clinical features of patients with Zika and dengue virus co-infection in Singapore. 
  • Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages. 
  • DNA bioassay-on-chip using SERS detection for dengue diagnosis. 
  • Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis. 
  • Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication. 
  • Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B. 
  • Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors. 
  • Dengue virus and autophagy. 
  • Dengue virus infection modifies mosquito blood-feeding behavior to increase transmission to the host. 
  • Dengue virus-elicited tryptase induces endothelial permeability and shock. 
  • Direct and indirect costs for hospitalized patients with dengue in Southern Sri Lanka. 
  • Drivers of Inter-individual Variation in Dengue Viral Load Dynamics. 
  • Economic Burden of Dengue Virus Infection at the Household Level Among Residents of Puerto Maldonado, Peru. 
  • Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka. 
  • Evaluation of the WHO 2009 classification for diagnosis of acute dengue in a large cohort of adults and children in Sri Lanka during a dengue-1 epidemic. 
  • Functional genomics approach for the identification of human host factors supporting dengue viral propagation. 
  • Geospatial analysis of dengue emergence in rural areas in the Southern Province of Sri Lanka. 
  • Global infections: recognition, management, and prevention. 
  • IL-10 levels in Dengue patients: some findings from the exceptional epidemiological conditions in Cuba. 
  • Immune correlates of protection for dengue: State of the art and research agenda. 
  • Immune responses to dengue virus in the skin. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immune synapses between mast cells and γδ T cells limit viral infection. 
  • Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice. 
  • Individual and Spatial Risk of Dengue Virus Infection in Puerto Maldonado, Peru. 
  • Influence of mast cells on dengue protective immunity and immune pathology. 
  • Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage. 
  • Peripheral serotonin causes dengue virus-induced thrombocytopenia through 5HT2 receptors. 
  • Probable and possible transfusion-transmitted dengue associated with NS1 antigen-negative but RNA confirmed-positive red blood cells. 
  • Rapid identification of dengue virus by reverse transcription-polymerase chain reaction using field-deployable instrumentation. 
  • Recent Advances in Dengue: Relevance to Puerto Rico. 
  • Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection. 
  • Telemedicine: climate change and mosquito-borne disease: a historical perspective. 
  • Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability. 
  • Transcriptional Profiling Confirms the Therapeutic Effects of Mast Cell Stabilization in a Dengue Disease Model. 
  • Unsuspected Dengue as a Cause of Acute Febrile Illness in Children and Adults in Western Nicaragua. 
  • Unsuspected dengue and acute febrile illness in rural and semi-urban southern Sri Lanka. 
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  Keywords of People

  • Pan, William Kuang-Yao, Elizabeth Brooks Reid and Whitelaw Reid Associate Professor, Environmental Sciences and Policy