Dengue Virus

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  Subject Areas on Research

  • A physical interaction network of dengue virus and human proteins. 
  • A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection. 
  • ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. 
  • Adaptive immune responses to primary and secondary dengue virus infections. 
  • Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection. 
  • An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target. 
  • Analysis of Dengue Serotype 4 in Sri Lanka during the 2012-2013 Dengue Epidemic. 
  • BPIFB3 Regulates Endoplasmic Reticulum Morphology To Facilitate Flavivirus Replication. 
  • Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis. 
  • Case series of fatal Leptospira spp./dengue virus co-infections-Puerto Rico, 2010-2012. 
  • Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania. 
  • Clinical features of patients with Zika and dengue virus co-infection in Singapore. 
  • Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage. 
  • Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages. 
  • DNA bioassay-on-chip using SERS detection for dengue diagnosis. 
  • Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis. 
  • Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication. 
  • Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B. 
  • Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors. 
  • Dengue virus and autophagy. 
  • Dengue virus infection modifies mosquito blood-feeding behavior to increase transmission to the host. 
  • Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. 
  • Dengue virus-elicited tryptase induces endothelial permeability and shock. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Distribution of Aedes mosquitoes in the Kilimanjaro Region of northern Tanzania. 
  • Drivers of Inter-individual Variation in Dengue Viral Load Dynamics. 
  • Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy. 
  • Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka. 
  • Evaluation of the WHO 2009 classification for diagnosis of acute dengue in a large cohort of adults and children in Sri Lanka during a dengue-1 epidemic. 
  • Evolutionary relationships of endemic/epidemic and sylvatic dengue viruses. 
  • Flavivirus RNA transactions from viral entry to genome replication. 
  • Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells. 
  • Functional genomics approach for the identification of human host factors supporting dengue viral propagation. 
  • Genetic variation in the 3' non-coding region of dengue viruses. 
  • Host cell transcriptome profile during wild-type and attenuated dengue virus infection. 
  • Identification and comparative analysis of hepatitis C virus-host cell protein interactions. 
  • Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication. 
  • Immune correlates of protection for dengue: State of the art and research agenda. 
  • Immune responses to dengue virus in the skin. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immune synapses between mast cells and γδ T cells limit viral infection. 
  • Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice. 
  • Individual and Spatial Risk of Dengue Virus Infection in Puerto Maldonado, Peru. 
  • Influence of mast cells on dengue protective immunity and immune pathology. 
  • Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage. 
  • Maternal Immunity and Vaccination Influence Disease Severity in Progeny in a Novel Mast Cell-Deficient Mouse Model of Severe Dengue. 
  • Maternal immunity and antibodies to dengue virus promote infection and Zika virus-induced microcephaly in fetuses. 
  • Microbes increase thermal sensitivity in the mosquito Aedes aegypti, with the potential to change disease distributions. 
  • Molecular determinants of plaque size as an indicator of dengue virus attenuation. 
  • Outcomes among children and adults at risk of severe dengue in Sri Lanka: Opportunity for outpatient case management in countries with high disease burden. 
  • Peripheral serotonin causes dengue virus-induced thrombocytopenia through 5HT2 receptors. 
  • Pervasive tertiary structure in the dengue virus RNA genome. 
  • Probable and possible transfusion-transmitted dengue associated with NS1 antigen-negative but RNA confirmed-positive red blood cells. 
  • Risk factors and biomarkers of severe dengue. 
  • Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. 
  • Seroprevalence of antibodies against chikungunya virus in Singapore resident adult population. 
  • Serum chymase levels correlate with severe dengue warning signs and clinical fluid accumulation in hospitalized pediatric patients. 
  • Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection. 
  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. 
  • Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability. 
  • Thermal biology of mosquito-borne disease. 
  • Transcriptional Profiling Confirms the Therapeutic Effects of Mast Cell Stabilization in a Dengue Disease Model. 
  • Unsuspected Dengue as a Cause of Acute Febrile Illness in Children and Adults in Western Nicaragua. 
  • Unsuspected dengue and acute febrile illness in rural and semi-urban southern Sri Lanka. 
  • ZIKV-Specific NS1 Epitopes as Serological Markers of Acute Zika Virus Infection.