Deoxyguanosine
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Subject Areas on Research
- Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress.
- Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons.
- Biochemical and immunological abnormalities in purine nucleoside phosphorylase deficient mice.
- Boron-containing oligodeoxyribonucleotide 14mer duplexes: enzymatic synthesis and melting studies.
- Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
- Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair.
- Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru.
- Cr(VI)-induced methylation and down-regulation of DNA repair genes and its association with markers of genetic damage in workers and 16HBE cells.
- Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots.
- Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model.
- Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site.
- Effects of personal air pollutant exposure on oxidative stress: Potential confounding by natural variation in melatonin levels.
- Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase.
- In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers.
- Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.
- Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine.
- Molecular analysis of genetic instability caused by chronic inflammation.
- Nitrated Polycyclic Aromatic Hydrocarbons and Arachidonic Acid Metabolisms Relevant to Cardiovascular Pathophysiology: Findings from a Panel Study in Healthy Adults.
- O6-3-[125I]iodobenzyl-2'-deoxyguanosine ([125I]IBdG): synthesis and evaluation of its usefulness as an agent for quantification of alkylguanine-DNA alkyltransferase (AGT).
- Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase.
- Oxidative DNA damage during night shift work.
- Oxidative DNA damage during sleep periods among nightshift workers.
- Oxidative stress impact on barrier function of porcine angular aqueous plexus cell monolayers.
- PM2.5 constituents and oxidative DNA damage in humans.
- Personal exposure to particulate PAHs and anthraquinone and oxidative DNA damages in humans.
- Rapid mtDNA deletion by oxidants in rat liver mitochondria after hemin exposure.
- Simultaneous quantification of urinary 6‑sulfatoxymelatonin and 8‑hydroxy‑2'‑deoxyguanosine using liquid chromatography-tandem mass spectrometry.
- The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa.
- The synthesis and anti-neoplastic activity of N2-isobutyryl-2'-deoxyguanosine-N7-cyanoborane derivatives.
- Urinary biomarkers of oxidative status.