Detergents

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  Subject Areas on Research

  • Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes. 
  • Activation of protein kinase C by oleic acid. Determination and analysis of inhibition by detergent micelles and physiologic membranes: requirement for free oleate. 
  • Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells. 
  • Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation. 
  • Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton. 
  • Aquatic risk assessment of a polycarboxylate dispersant polymer used in laundry detergents. 
  • Biogeochemistry of nonylphenol ethoxylates in urban estuarine sediments. 
  • Comparison of the efficacy of IGIV-C, 10% (caprylate/chromatography) and IGIV-SD, 10% as replacement therapy in primary immune deficiency. A randomized double-blind trial. 
  • Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus. 
  • Concentration-dependent behavior of nisin interaction with supported bilayer lipid membrane. 
  • Corneal toxicity secondary to inadvertent use of benzalkonium chloride preserved viscoelastic material in cataract surgery. 
  • Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular components. 
  • Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents. 
  • Cytosolic delivery of macromolecules. 3. Synthesis and characterization of acid-sensitive bis-detergents. 
  • Degradation of nonylphenol ethoxylates in estuarine sediment under aerobic and anaerobic conditions 
  • Detergents linked to polysaccharides: preparation and effects on membranes and cells. 
  • Differential extraction and enrichment of human sperm surface proteins in a proteome: identification of immunocontraceptive candidates. 
  • Effect of detergents on the thermal behavior of elastin-like polypeptides. 
  • Effective inactivation of human immunodeficiency virus with chlorhexidine antiseptics containing detergents and alcohol. 
  • Endoplasmic reticulum chaperone GRP94 subunit assembly is regulated through a defined oligomerization domain. 
  • Evidence that the src gene product of Rous sarcoma virus is membrane associated. 
  • Extrinsic pathway proteolytic activity. 
  • Generation of ramoplanin-resistant Staphylococcus aureus. 
  • Hepatic sulfite oxidase. The nature and function of the heme prosthetic groups. 
  • Jumping to rafts: gatekeeper role of bilayer elasticity. 
  • Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct. 
  • Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. 
  • Localization and characterization of the src-gene product of Rous sarcoma virus. 
  • Mammalian protein geranylgeranyltransferase. Subunit composition and metal requirements. 
  • Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis. 
  • Method for decellularizing skeletal muscle without detergents or proteolytic enzymes. 
  • Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22. 
  • Phosphorylation of telokin by cyclic nucleotide kinases and the identification of in vivo phosphorylation sites in smooth muscle. 
  • Purification and chemical characterization of melittin and acetylated derivatives. 
  • Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides. 
  • Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner. 
  • Reconstitution of secretory protein translocation from detergent-solubilized rough microsomes. 
  • Revisiting the mystery of fibronectin multimers: the fibronectin matrix is composed of fibronectin dimers cross-linked by non-covalent bonds. 
  • Ribosome-independent regulation of translocon composition and Sec61alpha conformation. 
  • Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. 
  • Solvent-detergent-treated fresh frozen plasma: a superior alternative to standard fresh frozen plasma? 
  • Sorting of lens aquaporins and connexins into raft and nonraft bilayers: role of protein homo-oligomerization. 
  • Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts. 
  • Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. 
  • Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts. 
  • Studies on photosystem I. I. Relationship of plastocyanin, cytochrome f and P700. 
  • Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system. 
  • Synaptic vesicle membrane proteins interact to form a multimeric complex. 
  • Temperature-modulated physiological characteristics of Candida albicans. 
  • The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19. 
  • The effect of detergents on the reduction of tetrazolium salts. 
  • The effect of plasmin on the subunit structure of human fibrinogen. 
  • The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes. 
  • The subunit structures of human plasma and platelet factor XIII (fibrin-stabilizing factor). 
  • Toxicity of a formulation of the insecticide indoxacarb to the tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), and the big-eyed bug, Geocoris punctipes (Hemiptera: Lygaeidae). 
  • Transbilayer peptide sorting between raft and nonraft bilayers: comparisons of detergent extraction and confocal microscopy. 
  • Trypanosoma brucei gambiense: partitioning of glycopeptides of bloodstream and procyclic forms in Triton X-114. 
  • Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. 
  • Unsaturated fatty acid requirement in Escherichia coli: mechanism of palmitate-induced inhibition of growth of strain WN1. 
  • Wound healing and treating wounds: Chronic wound care and management. 
  • X-ray diffraction to determine the thickness of raft and nonraft bilayers. 
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  Keywords of People

  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Biomedical Engineering
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic