Diffusion

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  Subject Areas on Research

  • A chimeric kinesin-1 head/kinesin-5 tail motor switches between diffusive and processive motility. 
  • A comment on the water permeability through planar lipid bilayers. 
  • A new view of convective-diffusive transport processes in the arterial intima. 
  • A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures. 
  • A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. 
  • Adjacent tissues (cartilage, bone) affect the functional integration of engineered calf cartilage in vitro. 
  • Advances and challenges in programming pattern formation using living cells. 
  • An N-terminal truncation of the ncd motor protein supports diffusional movement of microtubules in motility assays. 
  • An equivalent length model of microdialysis sampling. 
  • Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue. 
  • Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue. 
  • Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder. 
  • Anastral spindle assembly: a mathematical model. 
  • Applied electric fields accelerate the diffusion rate and increase the diffusion distance of DiI in fixed tissue. 
  • Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin. 
  • Available space and extracellular transport of macromolecules: effects of pore size and connectedness. 
  • Avidin-biotin interactions at vesicle surfaces: adsorption and binding, cross-bridge formation, and lateral interactions. 
  • Biochemistry. Friction in motor proteins. 
  • Boundary layer model for air pollutant concentrations due to highway traffic. 
  • CT perfusion parameter values in regions of diffusion abnormalities. 
  • Calmodulin activation by calcium transients in the postsynaptic density of dendritic spines. 
  • Carbon monoxide diffusion capacity: how low can you go for hematopoietic cell transplantation eligibility? 
  • Cell-specific constraints to the lateral diffusion of a membrane glycoprotein. 
  • Cerebral abscesses: investigation using apparent diffusion coefficient maps. 
  • Characterization of restricted diffusion in uni- and multi-lamellar vesicles using short distance iMQCs. 
  • Chemical waves in cell and developmental biology. 
  • Combining diffusion and perfusion differentiates tumor from bevacizumab-related imaging abnormality (bria). 
  • Comparison of muscle O(2) dynamics at different sites of the forearm flexor muscles during incremental handgrip exercise. 
  • Compartmental transport model of microbicide delivery by an intravaginal ring. 
  • Composition and transport properties of human ankle and knee cartilage. 
  • Control of osteoblast regeneration by a train of Erk activity waves. 
  • Controlled release of ethacrynic acid from poly(lactide-co-glycolide) films for glaucoma treatment. 
  • Convection-enhanced delivery of therapeutics for brain disease, and its optimization. 
  • Cortical depth dependence and implications on the neuronal specificity of the functional apparent diffusion coefficient contrast. 
  • Cortical depth dependence of the diffusion anisotropy in the human cortical gray matter in vivo. 
  • Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique. 
  • Deposition of aggregated nanoparticles--a theoretical and experimental study on the effect of aggregation state on the affinity between nanoparticles and a collector surface. 
  • Diffusion model for ultrasound-modulated light. 
  • Diffusion of low density lipoprotein-receptor complex on human fibroblasts. 
  • Diffusion tensor imaging: background, potential, and utility in psychiatric research. 
  • Diffusion weighted fMRI at 1.5 T. 
  • Diffusion-weighted MR imaging in acute stroke: theoretic considerations and clinical applications. 
  • Diffusion-weighted MR microscopy with fast spin-echo. 
  • Diffusion/microcirculation MRI in the rat brain. 
  • Diffusional anisotropy in collagenous tissues: fluorescence imaging of continuous point photobleaching. 
  • Direct in vivo measurement of targeted binding in a human tumor xenograft. 
  • Dose response of angiogenesis to basic fibroblast growth factor in rat corneal pocket assay: II. Numerical simulations. 
  • Dynamic adhesion of umbilical cord blood endothelial progenitor cells under laminar shear stress. 
  • Effect of cytoskeletal geometry on intracellular diffusion. 
  • Effects of humic acid and electrolytes on photocatalytic reactivity and transport of carbon nanoparticle aggregates in water. 
  • Effects of myocardial infarction on the distribution and transport of nutrients and oxygen in porcine myocardium. 
  • Efficiency, selectivity, and robustness of nucleocytoplasmic transport. 
  • Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties. 
  • Enhanced oxygen delivery induced by perfluorocarbon emulsions in capillary tube oxygenators. 
  • Enhanced spatial localization of neuronal activation using simultaneous apparent-diffusion-coefficient and blood-oxygenation functional magnetic resonance imaging. 
  • Evaluation of serum immunoglobulin concentrations in the perinatal period by use of a standardized method of measurement. 
  • Evaluation of the oxidation of organic compounds by aqueous suspensions of photosensitized hydroxylated-C60 fullerene aggregates. 
  • Experimental characterization of intermolecular multiple-quantum coherence pumping efficiency in solution NMR. 
  • Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific interactions in EcoRI catalysis. 
  • Factors controlling oxygen utilization. 
  • Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus. 
  • Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media. 
  • Fluorescence recovery kinetic analysis of gamma-tubulin binding to the mitotic spindle. 
  • Gene delivery through cell culture substrate adsorbed DNA complexes 
  • Glycolipid depletion using a ceramide analogue (PDMP) alters growth, adhesion, and membrane lipid organization in human A431 cells. 
  • Graph fission in an evolving voter model. 
  • Growth Kinetics of Single Polymer Particles in Solution via Active-Feedback 3D Tracking. 
  • Hyperpolarized helium-3 MR imaging of pulmonary function. 
  • Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data. 
  • In vitro evaluation of diffusion of lidocaine and alkalinized lidocaine through the polyurethane membrane of the endotracheal tube. 
  • In vivo lysis of L5178Y cells in the establishment of the tumor-dormant state in DBA/2 mice. 
  • In vivo measurement of proton diffusion in the presence of coherent motion. 
  • Increased brain apparent diffusion coefficient in children with neurofibromatosis type 1. 
  • Increasing the computational efficiency of a bidomain model of defibrillation using a time-dependent activating function. 
  • Infarct volume on apparent diffusion coefficient maps correlates with length of stay and outcome after middle cerebral artery stroke. 
  • Influence of Sulfide Nanoparticles on Dissolved Mercury and Zinc Quantification by Diffusive Gradient in Thin-Film Passive Samplers. 
  • Interpretive criteria and quality control parameters for testing bacterial susceptibility to the fluoroquinolone PD131628. 
  • Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin. 
  • Knee-loading modality drives molecular transport in mouse femur. 
  • Label-Free Measurements of Tenofovir Diffusion Coefficients in a Microbicide Gel Using Raman Spectroscopy. 
  • Laser-induced heating in optical traps. 
  • Lateral diffusion in planar lipid bilayers. 
  • Leukocyte chemoattraction by 1,2-diacylglycerol. 
  • Lifetime enhancement of ultrasmall fluorescent liquid polymeric film based optodes by diffusion-induced self-recovery after photobleaching. 
  • Light-driven translocation of signaling proteins in vertebrate photoreceptors. 
  • Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics. 
  • Mass transfer in the dissolution of a multicomponent liquid droplet in an immiscible liquid environment. 
  • Mathematical modeling of Erk activity waves in regenerating zebrafish scales. 
  • Maximization of contrast-to-noise ratio to distinguish diffusion and microcirculatory flow. 
  • Measurement and modulation of nonoxynol-9 diffusion and bioactivity against spermatozoa in human cervical mucus. 
  • Measuring macrodiffusion coefficients in microbicide hydrogels via postphotoactivation scanning. 
  • Mechanism of detection of acute cerebral ischemia in rats by diffusion-weighted magnetic resonance microscopy. 
  • Mechanisms of apparent affinity variation of guarded receptors. 
  • Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores. 
  • Microscale diffusion properties of the cartilage pericellular matrix measured using 3D scanning microphotolysis. 
  • Microtubule cross-linking triggers the directional motility of kinesin-5. 
  • Modeling the relative impact of capsular tissue effects on implanted glucose sensor time lag and signal attenuation. 
  • Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. 
  • Molecular mobility on the cell surface. 
  • Multiple-particle tracking and two-point microrheology in cells. 
  • Multiscale photoacoustic tomography using reversibly switchable thermochromics. 
  • New sensitive micro-measurements of dynamic surface tension and diffusion coefficients: Validated and tested for the adsorption of 1-Octanol at a microscopic air-water interface and its dissolution into water. 
  • Noise reduction by diffusional dissipation in a minimal quorum sensing motif. 
  • Non-invasive thermometry using magnetic resonance diffusion imaging: potential for application in hyperthermic oncology. 
  • Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion? 
  • Nonischemic causes of hyperintense signals on diffusion-weighted magnetic resonance images: a pictorial essay. 
  • Numerical simulations of ethacrynic acid transport from precorneal region to trabecular meshwork. 
  • On the complementary relationship between marginal nitrogen and water-use efficiencies among Pinus taeda leaves grown under ambient and CO2-enriched environments. 
  • On the down-sampling of diffusion MRI data along the angular dimension. 
  • Optimized isotropic diffusion weighting. 
  • Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain. 
  • Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging. 
  • Pigmentation pattern formation in butterflies: experiments and models. 
  • Potential landscape and flux framework of nonequilibrium networks: robustness, dissipation, and coherence of biochemical oscillations. 
  • Pre- and postmortem diffusion coefficients in rat neural and muscle tissues. 
  • Preorganized secondary structure as an important determinant of fast protein folding. 
  • Probabilistic pharmacokinetic models of decompression sickness in humans: Part 2, coupled perfusion-diffusion models. 
  • Protein folding dynamics: quantitative comparison between theory and experiment. 
  • Pulmonary gas exchange in diving. 
  • Pulmonary gas exchange in humans exercising at sea level and simulated altitude. 
  • Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem. 
  • Quantitative assessment of diffusion abnormalities in posterior reversible encephalopathy syndrome. 
  • Rate of buthionine sulfoximine entry into brain and xenotransplanted human gliomas. 
  • Renewal Reward Perspective on Linear Switching Diffusion Systems in Models of Intracellular Transport. 
  • Retinitis pigmentosa: clinical management based on current concepts. 
  • Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro. 
  • Sensing of molecules using quantum dynamics. 
  • Simulation of electron transfer between cytochrome C2 and the bacterial photosynthetic reaction center: Brownian dynamics analysis of the native proteins and double mutants. 
  • Single-lead f-wave extraction using diffusion geometry. 
  • Site-specific effects of compression on macromolecular diffusion in articular cartilage. 
  • Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching. 
  • Small molecule delivery across a perforated artificial membrane by thermoreversible hydrogel poloxamer 407. 
  • Spatiotemporal distribution modeling of PET tracer uptake in solid tumors. 
  • Spectral diffusion: an algorithm for robust material decomposition of spectral CT data. 
  • Spectrophotometric analysis of molecular transport in gels. 
  • Spherical Caps in Cell Polarization. 
  • Spinal cord neural anatomy in rats examined by in vivo magnetic resonance microscopy. 
  • Squeezing flows of vaginal gel formulations relevant to microbicide drug delivery. 
  • Study of diffusion in erythrocyte suspension using internal magnetic field inhomogeneity. 
  • The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. 
  • The chemical biology of nitric oxide: implications in cellular signaling. 
  • The effect of advection on the nutrient reservoir in the North Atlantic subtropical gyre. 
  • The effect of aging on the apparent diffusion coefficient of normal-appearing white matter. 
  • The effect of hydrogen bonding on the diffusion of water in n-alkanes and n-alcohols measured with a novel single microdroplet method. 
  • The effect of surface agitation on ultrasound-mediated gene transfer in vitro 
  • The hierarchical assembly of septins revealed by high-speed AFM. 
  • The influence of xenon, nitrous oxide and nitrogen on gas bubble expansion during cardiopulmonary bypass. 
  • The nature of fluorocarbon enhanced cerebral oxygen transport. 
  • The removal of H2S from process air by diffusion into activated sludge. 
  • The use of gradient flow compensation to separate diffusion and microcirculatory flow in MRI. 
  • Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium. 
  • Transport theory for HIV diffusion through in vivo distributions of topical microbicide gels. 
  • Transscleral diffusion of ethacrynic acid and sodium fluorescein. 
  • Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. 
  • Use of decrease in apparent diffusion coefficient values to predict infarct age. 
  • Use of exponential diffusion imaging to determine the age of ischemic infarcts. 
  • Vaginal deployment and tenofovir delivery by microbicide gels. 
  • Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. 
  • Viscosity measurements of methanol-water and acetonitrile-water mixtures at pressures up to 3500 bar using a novel capillary time-of-flight viscometer. 
  • Water mobility within bovine cervical mucus. 
  • Waves in Embryonic Development. 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
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  Keywords of People

  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • Jokerst, Nan Marie, J. A. Jones Distinguished Professor of Electrical and Computer Engineering, Nicholas Institute-Energy Initiative
  • Katz, David F., Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
  • Newell, Richard G., Adjunct Professor, Environmental Sciences and Policy
  • Oas, Terrence Gilbert, Professor of Biochemistry, Biochemistry
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Virgin, Lawrence N., Professor of Mechanical Engineering and Materials Science, Thomas Lord Department of Mechanical Engineering and Materials Science