Dimethylallyltranstransferase

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  Subject Areas on Research

  • Biochemistry of protein prenylation. 
  • Caged protein prenyltransferase substrates: tools for understanding protein prenylation. 
  • Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells. 
  • Identification of a cysteine residue essential for activity of protein farnesyltransferase. Cys299 is exposed only upon removal of zinc from the enzyme. 
  • In vitro processing of recombinant G protein gamma subunits. Requirements for assembly of an active beta gamma complex. 
  • Long-Chain Polyprenols Promote Spore Wall Formation in Saccharomyces cerevisiae. 
  • Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: implications for virulence. 
  • The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. 
  • cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.